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The map label for this gene is cat [H]

Identifier: 158422329

GI number: 158422329

Start: 784491

End: 785126

Strand: Direct

Name: cat [H]

Synonym: AZC_0705

Alternate gene names: 158422329

Gene position: 784491-785126 (Clockwise)

Preceding gene: 158422328

Following gene: 158422330

Centisome position: 14.61

GC content: 66.04

Gene sequence:

>636_bases
ATGAAGAAGCTCGGCCTCGCCCCTCTCATCGACCCCACCGCCAGCGTGAAGGACTCAAGCCTCGGCCGCTATACGGAGGT
GGGCGCGCGGGTGAAGCTGCTGGAAGTGGCGATGGGGGACTATTCCTACATCGAGCATGACAGCGACATGGCCTACACGC
AGGTGGGCAGGTTCTGCTCCATCGCGGCGCTGACGCGCATCAATCCCGGCAACCACCCCATGTGGCGAGCCAGCCAGTCC
CATTTCACCTATCGCGCCTCCACCTATTTCGACGATGCCCAAGACGAGCCGGACTTCTTCCAGTGGCGGCGTGACCATGG
CGTGACGCTTGGTCATGACATCTGGGTCGGGCATGGCGCCGTCATCCTGCCCGGCCGCACCATCGGGACCGGTGCCGTGG
TGGCGGCCGGTGCCGTCGTCACCAAGGACGTCCCGCCCTATGCCATCGTCGCGGGTGTGCCGGCGCGCATCGTGAAATGG
CGCTTTCCCGAGACCATTGCGGAACGCCTTCAGGCGCTCGCCTGGTGGGACTGGGACCATGGGTCGCTGCGCGCCGCGCT
GGAGGATTTCCGCGCACTGCCCGTGGAAGGCTTCCTTGAGAAATACGAGCGGCGGGCGGTCTCCGCCGCGGAGTGA

Upstream 100 bases:

>100_bases
CGAGGCGCGAACGTGGCGGCAGTCCGCCCGGGCCGTCGGACCGTCGTACGGCTGTCATCGGGGCGTCGCATTTTCCGCCG
CCTCCGGAGACAGGACTGTC

Downstream 100 bases:

>100_bases
GGTGGCGCGGCCATCCGCTGGCGCCGGGGGGATATGTCGGGCCGGAAACTCCCCTTGGCCGGCGAACAGTGCTATGGCCT
CGCCATGACTGCCGCTCCCT

Product: acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKKLGLAPLIDPTASVKDSSLGRYTEVGARVKLLEVAMGDYSYIEHDSDMAYTQVGRFCSIAALTRINPGNHPMWRASQS
HFTYRASTYFDDAQDEPDFFQWRRDHGVTLGHDIWVGHGAVILPGRTIGTGAVVAAGAVVTKDVPPYAIVAGVPARIVKW
RFPETIAERLQALAWWDWDHGSLRAALEDFRALPVEGFLEKYERRAVSAAE

Sequences:

>Translated_211_residues
MKKLGLAPLIDPTASVKDSSLGRYTEVGARVKLLEVAMGDYSYIEHDSDMAYTQVGRFCSIAALTRINPGNHPMWRASQS
HFTYRASTYFDDAQDEPDFFQWRRDHGVTLGHDIWVGHGAVILPGRTIGTGAVVAAGAVVTKDVPPYAIVAGVPARIVKW
RFPETIAERLQALAWWDWDHGSLRAALEDFRALPVEGFLEKYERRAVSAAE
>Mature_211_residues
MKKLGLAPLIDPTASVKDSSLGRYTEVGARVKLLEVAMGDYSYIEHDSDMAYTQVGRFCSIAALTRINPGNHPMWRASQS
HFTYRASTYFDDAQDEPDFFQWRRDHGVTLGHDIWVGHGAVILPGRTIGTGAVVAAGAVVTKDVPPYAIVAGVPARIVKW
RFPETIAERLQALAWWDWDHGSLRAALEDFRALPVEGFLEKYERRAVSAAE

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=52, Percent_Identity=61.5384615384615, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786537, Length=52, Percent_Identity=48.0769230769231, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 23445; Mature: 23445

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLGLAPLIDPTASVKDSSLGRYTEVGARVKLLEVAMGDYSYIEHDSDMAYTQVGRFCS
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEHHCCCCEEECCCCHHHHHHHHHHH
IAALTRINPGNHPMWRASQSHFTYRASTYFDDAQDEPDFFQWRRDHGVTLGHDIWVGHGA
HHHHEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEECCEEEECCCE
VILPGRTIGTGAVVAAGAVVTKDVPPYAIVAGVPARIVKWRFPETIAERLQALAWWDWDH
EEECCCCCCCCHHHHHCEEEECCCCCEEEEECCCHHHHEECCCHHHHHHHHHHHCCCCCC
GSLRAALEDFRALPVEGFLEKYERRAVSAAE
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLGLAPLIDPTASVKDSSLGRYTEVGARVKLLEVAMGDYSYIEHDSDMAYTQVGRFCS
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEHHCCCCEEECCCCHHHHHHHHHHH
IAALTRINPGNHPMWRASQSHFTYRASTYFDDAQDEPDFFQWRRDHGVTLGHDIWVGHGA
HHHHEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEECCEEEECCCE
VILPGRTIGTGAVVAAGAVVTKDVPPYAIVAGVPARIVKWRFPETIAERLQALAWWDWDH
EEECCCCCCCCHHHHHCEEEECCCCCEEEEECCCHHHHEECCCHHHHHHHHHHHCCCCCC
GSLRAALEDFRALPVEGFLEKYERRAVSAAE
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA