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The map label for this gene is 158422322

Identifier: 158422322

GI number: 158422322

Start: 773917

End: 774873

Strand: Direct

Name: 158422322

Synonym: AZC_0698

Alternate gene names: NA

Gene position: 773917-774873 (Clockwise)

Preceding gene: 158422320

Following gene: 158422326

Centisome position: 14.41

GC content: 66.67

Gene sequence:

>957_bases
TTGCCATTCTCCTGTCCAGAGACACGGTCGTCCCGCCACGCAGGCTCCGAGAGCAGCGACGGGAGACCCGGACAGAGGAT
GACGACCATGACCCAAACCACGAACAGTCTCGTGTTTCCCGACACGTTCCAGATCCGCGACATTCCCACCAACGGCACCA
CGCTCCACGTCCGCACGGGCGGGAAGGGGCCGGCCGTCCTGCTACTCCACGGCTATGGCGAGACCGGCGACATGTGGGTG
CCGCTTGCCGCGGATCTCGCCGCCGATCACTTCGTCATCGTCCCGGACCTGCGCGGCATGGGCCGCTCCGCAAAGCCTGA
GGGCGGCTATGACAAAAAGACCCAGGGGCAGGACATGGCCGGGCTGCTCGATGCCCTCGGCATTGCGGCGGTGGATCTCG
TCACCCACGACATCGGCAACATGGTCGGCTTCGCCTTCGCCGCGCAGCATCGCGACCGGGTGCACAGCTTCGTTCTGATC
GACGCGCCCTTGCCCGGCGTGGGGCCATGGGAGGAGATCCTGAAGAACCCGCTGCTGTGGCATTTCCGCTTCGGCGGGCC
GGACATGGAGCGCCTCGTGGCCGGTCGCGAGCGTATCTATCTCGACCGCTTCTGGAACGAGTTCTCGGCCACGCCCGCCC
GCTTCAGCGAGGCCGCGCGGGAGCATTATGCGGCGCTCTATGCGCAGCCCGGCGCCATGCATGCGGGCTTTTCCCAGTTC
GCCGCCTTCGATCAGGACGCCATCGACAATCAGGCCTTCCTGAAGGCGGGCAAGCTGACCATTCCGGTGCTCGCGCTCGG
CGGAGAGAAATCCTTCGGCCTCGGCATGGGGCAGGTGATGGCCTTTGCGGCGGAGGACGTGACGAGCGGCGTGGTGCCGG
ATGCCGGCCACTGGATCATGGAGGAAAACCCCGCCGCCACGGTGGCGCTGGTGCGCGACTTCCTGCCGAAGGCTTGA

Upstream 100 bases:

>100_bases
GCCACCGCCACGAAGGCGGCTACCCCGTCGAGCTTGAGCATTGTTCGAATAATCCGTAAACGGGTTTCGCCTTCTGCCGG
CTAACCCGGACAATGGAGCT

Downstream 100 bases:

>100_bases
AACTGCGGCAAAGGCCCGGCGTCTGCGTGCCGGGCCTTTCGCTATCGGGCGGTCGCCCTCACTCCGCCGCCTGCGCCGGG
GCGACGGGCGGAGTGCGGAA

Product: hydrolase

Products: NA

Alternate protein names: SEH; Cytosolic epoxide hydrolase; cEH; Epoxide hydratase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPFSCPETRSSRHAGSESSDGRPGQRMTTMTQTTNSLVFPDTFQIRDIPTNGTTLHVRTGGKGPAVLLLHGYGETGDMWV
PLAADLAADHFVIVPDLRGMGRSAKPEGGYDKKTQGQDMAGLLDALGIAAVDLVTHDIGNMVGFAFAAQHRDRVHSFVLI
DAPLPGVGPWEEILKNPLLWHFRFGGPDMERLVAGRERIYLDRFWNEFSATPARFSEAAREHYAALYAQPGAMHAGFSQF
AAFDQDAIDNQAFLKAGKLTIPVLALGGEKSFGLGMGQVMAFAAEDVTSGVVPDAGHWIMEENPAATVALVRDFLPKA

Sequences:

>Translated_318_residues
MPFSCPETRSSRHAGSESSDGRPGQRMTTMTQTTNSLVFPDTFQIRDIPTNGTTLHVRTGGKGPAVLLLHGYGETGDMWV
PLAADLAADHFVIVPDLRGMGRSAKPEGGYDKKTQGQDMAGLLDALGIAAVDLVTHDIGNMVGFAFAAQHRDRVHSFVLI
DAPLPGVGPWEEILKNPLLWHFRFGGPDMERLVAGRERIYLDRFWNEFSATPARFSEAAREHYAALYAQPGAMHAGFSQF
AAFDQDAIDNQAFLKAGKLTIPVLALGGEKSFGLGMGQVMAFAAEDVTSGVVPDAGHWIMEENPAATVALVRDFLPKA
>Mature_317_residues
PFSCPETRSSRHAGSESSDGRPGQRMTTMTQTTNSLVFPDTFQIRDIPTNGTTLHVRTGGKGPAVLLLHGYGETGDMWVP
LAADLAADHFVIVPDLRGMGRSAKPEGGYDKKTQGQDMAGLLDALGIAAVDLVTHDIGNMVGFAFAAQHRDRVHSFVLID
APLPGVGPWEEILKNPLLWHFRFGGPDMERLVAGRERIYLDRFWNEFSATPARFSEAAREHYAALYAQPGAMHAGFSQFA
AFDQDAIDNQAFLKAGKLTIPVLALGGEKSFGLGMGQVMAFAAEDVTSGVVPDAGHWIMEENPAATVALVRDFLPKA

Specific function: Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR010497 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF06441 EHN [H]

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 34365; Mature: 34234

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSCPETRSSRHAGSESSDGRPGQRMTTMTQTTNSLVFPDTFQIRDIPTNGTTLHVRTG
CCCCCCCCCCHHCCCCCCCCCCCCCCEEEEECCCCCEECCCCEEEEEECCCCCEEEEEEC
GKGPAVLLLHGYGETGDMWVPLAADLAADHFVIVPDLRGMGRSAKPEGGYDKKTQGQDMA
CCCCEEEEEECCCCCCCEEEEEHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHH
GLLDALGIAAVDLVTHDIGNMVGFAFAAQHRDRVHSFVLIDAPLPGVGPWEEILKNPLLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHCCCEEE
HFRFGGPDMERLVAGRERIYLDRFWNEFSATPARFSEAAREHYAALYAQPGAMHAGFSQF
EEECCCCCHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AAFDQDAIDNQAFLKAGKLTIPVLALGGEKSFGLGMGQVMAFAAEDVTSGVVPDAGHWIM
HHCCHHHCCCHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEE
EENPAATVALVRDFLPKA
CCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PFSCPETRSSRHAGSESSDGRPGQRMTTMTQTTNSLVFPDTFQIRDIPTNGTTLHVRTG
CCCCCCCCCHHCCCCCCCCCCCCCCEEEEECCCCCEECCCCEEEEEECCCCCEEEEEEC
GKGPAVLLLHGYGETGDMWVPLAADLAADHFVIVPDLRGMGRSAKPEGGYDKKTQGQDMA
CCCCEEEEEECCCCCCCEEEEEHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHH
GLLDALGIAAVDLVTHDIGNMVGFAFAAQHRDRVHSFVLIDAPLPGVGPWEEILKNPLLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHCCCEEE
HFRFGGPDMERLVAGRERIYLDRFWNEFSATPARFSEAAREHYAALYAQPGAMHAGFSQF
EEECCCCCHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AAFDQDAIDNQAFLKAGKLTIPVLALGGEKSFGLGMGQVMAFAAEDVTSGVVPDAGHWIM
HHCCHHHCCCHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEE
EENPAATVALVRDFLPKA
CCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9578475 [H]