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The map label for this gene is cysJ [H]

Identifier: 158422304

GI number: 158422304

Start: 750547

End: 752160

Strand: Reverse

Name: cysJ [H]

Synonym: AZC_0680

Alternate gene names: 158422304

Gene position: 752160-750547 (Counterclockwise)

Preceding gene: 158422305

Following gene: 158422303

Centisome position: 14.01

GC content: 69.95

Gene sequence:

>1614_bases
ATGACCCTCCAGACGCGAACCCCTCTGGTGCCCTTCCTGCCGGAAAGCGCCCCTTTCTCGGCCGAGCAGCGGGCCTGGCT
CAACGGCTTCTTCGCCGGCATTTTCTCCGGCGAGGCGCCGGCCGGCGCCACCGTCCTGTCTCCGGCCGAGGGCGCGGCCC
TCATGGCCCCGCCCGCGAGTGCTGAGGAAGACGACGGTGCGCCCTGGCATGATGCCTCGATGCCGCTCGACGAGCGCATG
AAGCTCGCCGAAGGCAAGCCGCTCGCCCGGCGGATGATGGCGGCCATGGCGCAGCAGGACTGCGGCCAGTGCGGCTATAT
CTGCGACAGCTATTCCAAGGCGCTCGCCTCGGGCGCCGAGACCAAGCTCAATCTCTGCGCCCCCGGCGGCAAGGAGACGC
TGCGGATGCTGAAGCAGCTCGCCACCGAGCTGGATGGCGCACCCGCACCGGCGCCCACCGCGCCCGGTGCCGAGGCCGCA
ACCGCCCCGGCCGCCGCTGCGCCGAGGGGCACGCGCGACAATCCCGCCGAAGTCACCTTCCTCGGCCGCTTCCGCCTCAA
CAAGGACGGCTCCGAGAAGGAGACGTGGCACGTGGATTTCGACCTCGAAGGCTCGGGGCTCGACTACAAGGCGGGCGACA
GCTTCGGCCTGTTCCCGGTGAATGATCCCGGCCTCGTGGCGGACGTTCTCGCCGCTTTGCATGCCCCTGCCGACTTCCCC
ATCGGCGAGAAGACGCTGGAGCAGGTGCTCACCAAGGAGGTGTGCCTGAAATCGCCCCCCGACACGCTCTTCACCCTCAT
CTCCTACATCACCGGCGGGGCCCGCAAGGACAACGCGAAGGCGCTGGCGGCGGGCGAGGACCCGGATGGCGATGCGGCAA
CGCTCGACGTGCTGGCGGCGCTGGAGAAATTCCCCGGCATCCGGCCGGACCCGGAGGCCTTCGTGGAGTGCCTGGAGCCG
CTCCAGCCGCGCCTTTATTCCATCTCTTCCAGCCCCGCCGCCACCCCCGGCCGGCTCTCGCTGACGGTGGATGCGGTGCG
CTACGACCATCAGGGCCGCACGCGGCTCGGGGTGTGCTCCACCTTCCTCGGCGGGCGCGTGGCGCCAGGCACGCGGATGA
AGGCCTATGTGCAGAAGGCCCACGGCTTCGGCCTGCCGACGGATGCGGCGCGGCCCGTCGTCATGGTCGGCCCCGGCACG
GGCATCGCCCCCTTCCGCGCCTTCCTGCATGAGCGCATGGCGACGAAAGCGCCGGGTCGCAACTGGCTGTTCTTCGGCCA
CCAGCGCTCGGCCACCGACTTCTTCTATGAAGACGAACTCGCCGGAATGCAGGCCGCGGGCGTGCTCTCGCGGCTCGACA
CCGCATGGTCCCGCGAGGGCGGGGAGAAGGTCTATGTGCAGGATCGCATCCGCGCCGCAGGCCCCGAACTTTGGGCGTGG
TTCGAGGAAGGCGCGCACTTCTATGTCTGCGGCGATGCCAAGCGCATGGCCAAGGATGTGGAGGCCGCCGTCGCGGATGT
GGCCGCCACCCATGGCGGCCTCGGGGCCGAGGGCGGTGCCCGCTTCGTGGCGGAACTGAAGAAGGCCGGCCGCTATCAGG
CGGACGTCTACTGA

Upstream 100 bases:

>100_bases
CTGCGCAAAGGCTGCCGGGCGAGACCTTCGCCGCCTTCACCCGCCGCCTTGGCCCCGCCGCCCTGAAATCCCTCGTCGAG
ACCGCCATGGAGCGCGCCGA

Downstream 100 bases:

>100_bases
GCGCAGGAAAACCGGAGACAGCGCCTCATGAACGCCCCGCTTTCCTCGCCTCAGGCGACATCGACCACCTGTCCCTATTG
CGGCGTCGGCTGCGGCGTGA

Product: sulfite reductase

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MTLQTRTPLVPFLPESAPFSAEQRAWLNGFFAGIFSGEAPAGATVLSPAEGAALMAPPASAEEDDGAPWHDASMPLDERM
KLAEGKPLARRMMAAMAQQDCGQCGYICDSYSKALASGAETKLNLCAPGGKETLRMLKQLATELDGAPAPAPTAPGAEAA
TAPAAAAPRGTRDNPAEVTFLGRFRLNKDGSEKETWHVDFDLEGSGLDYKAGDSFGLFPVNDPGLVADVLAALHAPADFP
IGEKTLEQVLTKEVCLKSPPDTLFTLISYITGGARKDNAKALAAGEDPDGDAATLDVLAALEKFPGIRPDPEAFVECLEP
LQPRLYSISSSPAATPGRLSLTVDAVRYDHQGRTRLGVCSTFLGGRVAPGTRMKAYVQKAHGFGLPTDAARPVVMVGPGT
GIAPFRAFLHERMATKAPGRNWLFFGHQRSATDFFYEDELAGMQAAGVLSRLDTAWSREGGEKVYVQDRIRAAGPELWAW
FEEGAHFYVCGDAKRMAKDVEAAVADVAATHGGLGAEGGARFVAELKKAGRYQADVY

Sequences:

>Translated_537_residues
MTLQTRTPLVPFLPESAPFSAEQRAWLNGFFAGIFSGEAPAGATVLSPAEGAALMAPPASAEEDDGAPWHDASMPLDERM
KLAEGKPLARRMMAAMAQQDCGQCGYICDSYSKALASGAETKLNLCAPGGKETLRMLKQLATELDGAPAPAPTAPGAEAA
TAPAAAAPRGTRDNPAEVTFLGRFRLNKDGSEKETWHVDFDLEGSGLDYKAGDSFGLFPVNDPGLVADVLAALHAPADFP
IGEKTLEQVLTKEVCLKSPPDTLFTLISYITGGARKDNAKALAAGEDPDGDAATLDVLAALEKFPGIRPDPEAFVECLEP
LQPRLYSISSSPAATPGRLSLTVDAVRYDHQGRTRLGVCSTFLGGRVAPGTRMKAYVQKAHGFGLPTDAARPVVMVGPGT
GIAPFRAFLHERMATKAPGRNWLFFGHQRSATDFFYEDELAGMQAAGVLSRLDTAWSREGGEKVYVQDRIRAAGPELWAW
FEEGAHFYVCGDAKRMAKDVEAAVADVAATHGGLGAEGGARFVAELKKAGRYQADVY
>Mature_536_residues
TLQTRTPLVPFLPESAPFSAEQRAWLNGFFAGIFSGEAPAGATVLSPAEGAALMAPPASAEEDDGAPWHDASMPLDERMK
LAEGKPLARRMMAAMAQQDCGQCGYICDSYSKALASGAETKLNLCAPGGKETLRMLKQLATELDGAPAPAPTAPGAEAAT
APAAAAPRGTRDNPAEVTFLGRFRLNKDGSEKETWHVDFDLEGSGLDYKAGDSFGLFPVNDPGLVADVLAALHAPADFPI
GEKTLEQVLTKEVCLKSPPDTLFTLISYITGGARKDNAKALAAGEDPDGDAATLDVLAALEKFPGIRPDPEAFVECLEPL
QPRLYSISSSPAATPGRLSLTVDAVRYDHQGRTRLGVCSTFLGGRVAPGTRMKAYVQKAHGFGLPTDAARPVVMVGPGTG
IAPFRAFLHERMATKAPGRNWLFFGHQRSATDFFYEDELAGMQAAGVLSRLDTAWSREGGEKVYVQDRIRAAGPELWAWF
EEGAHFYVCGDAKRMAKDVEAAVADVAATHGGLGAEGGARFVAELKKAGRYQADVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=399, Percent_Identity=31.328320802005, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI24041029, Length=392, Percent_Identity=33.9285714285714, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI10835173, Length=404, Percent_Identity=32.1782178217822, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI40254422, Length=396, Percent_Identity=33.0808080808081, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI169790956, Length=418, Percent_Identity=28.7081339712919, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI169790958, Length=418, Percent_Identity=28.7081339712919, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7657393, Length=373, Percent_Identity=30.2949061662198, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI221316705, Length=382, Percent_Identity=29.5811518324607, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI221316709, Length=375, Percent_Identity=29.3333333333333, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI221316707, Length=330, Percent_Identity=29.3939393939394, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1789123, Length=400, Percent_Identity=40, Blast_Score=286, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17554134, Length=393, Percent_Identity=30.2798982188295, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17566446, Length=470, Percent_Identity=25.1063829787234, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17531441, Length=250, Percent_Identity=28, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321143, Length=376, Percent_Identity=27.9255319148936, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6321832, Length=414, Percent_Identity=25.8454106280193, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6325305, Length=247, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24582192, Length=448, Percent_Identity=31.0267857142857, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI17137192, Length=448, Percent_Identity=31.4732142857143, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI78706872, Length=377, Percent_Identity=34.2175066312997, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24583543, Length=377, Percent_Identity=34.2175066312997, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI78706876, Length=377, Percent_Identity=34.2175066312997, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24660907, Length=232, Percent_Identity=31.8965517241379, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24660903, Length=232, Percent_Identity=31.8965517241379, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 56962; Mature: 56831

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQTRTPLVPFLPESAPFSAEQRAWLNGFFAGIFSGEAPAGATVLSPAEGAALMAPPAS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCCCC
AEEDDGAPWHDASMPLDERMKLAEGKPLARRMMAAMAQQDCGQCGYICDSYSKALASGAE
CCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
TKLNLCAPGGKETLRMLKQLATELDGAPAPAPTAPGAEAATAPAAAAPRGTRDNPAEVTF
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
LGRFRLNKDGSEKETWHVDFDLEGSGLDYKAGDSFGLFPVNDPGLVADVLAALHAPADFP
EEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCC
IGEKTLEQVLTKEVCLKSPPDTLFTLISYITGGARKDNAKALAAGEDPDGDAATLDVLAA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
LEKFPGIRPDPEAFVECLEPLQPRLYSISSSPAATPGRLSLTVDAVRYDHQGRTRLGVCS
HHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHH
TFLGGRVAPGTRMKAYVQKAHGFGLPTDAARPVVMVGPGTGIAPFRAFLHERMATKAPGR
HHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCC
NWLFFGHQRSATDFFYEDELAGMQAAGVLSRLDTAWSREGGEKVYVQDRIRAAGPELWAW
CEEEECCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHH
FEEGAHFYVCGDAKRMAKDVEAAVADVAATHGGLGAEGGARFVAELKKAGRYQADVY
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TLQTRTPLVPFLPESAPFSAEQRAWLNGFFAGIFSGEAPAGATVLSPAEGAALMAPPAS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCCCC
AEEDDGAPWHDASMPLDERMKLAEGKPLARRMMAAMAQQDCGQCGYICDSYSKALASGAE
CCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
TKLNLCAPGGKETLRMLKQLATELDGAPAPAPTAPGAEAATAPAAAAPRGTRDNPAEVTF
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
LGRFRLNKDGSEKETWHVDFDLEGSGLDYKAGDSFGLFPVNDPGLVADVLAALHAPADFP
EEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCC
IGEKTLEQVLTKEVCLKSPPDTLFTLISYITGGARKDNAKALAAGEDPDGDAATLDVLAA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
LEKFPGIRPDPEAFVECLEPLQPRLYSISSSPAATPGRLSLTVDAVRYDHQGRTRLGVCS
HHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHH
TFLGGRVAPGTRMKAYVQKAHGFGLPTDAARPVVMVGPGTGIAPFRAFLHERMATKAPGR
HHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCC
NWLFFGHQRSATDFFYEDELAGMQAAGVLSRLDTAWSREGGEKVYVQDRIRAAGPELWAW
CEEEECCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHH
FEEGAHFYVCGDAKRMAKDVEAAVADVAATHGGLGAEGGARFVAELKKAGRYQADVY
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA