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The map label for this gene is lysR [H]

Identifier: 158422296

GI number: 158422296

Start: 743248

End: 744132

Strand: Direct

Name: lysR [H]

Synonym: AZC_0672

Alternate gene names: 158422296

Gene position: 743248-744132 (Clockwise)

Preceding gene: 158422295

Following gene: 158422300

Centisome position: 13.84

GC content: 70.17

Gene sequence:

>885_bases
ATGACGCTCGATCAGCTCAAGGTCTTCGTGGCGGTCGCGGATCATCTTCACATGACCCGCGCCGCCGAGGCGCTGCACAT
GACGCAATCGGCCGTCAGCGCCTCCATCGCCGCCCTCGAACAGTCCTGCGGACAACCCTTGTTTGACCGGGTCGGCCGGC
GGATCGAACTCACCGCCGCCGGTCGTCTCTTTGTGGGAGAGGCGCAGGCCATCCTGAAGCGGGTGGCACAGGCGCGCGAT
GCGCTCTCGGACCTCGCGGGCCTTGCGCGCGGCACCCTCACTCTCCACGCCAGCCAGACCATCGCCAATTACTGGCTCGC
CCCGCGCATGAATGCCTTCCACGCCGCTCATCCGGGCATCCGGCTGGAGCTCGGCATCGGCAACACCACGCAGGTGGCGG
CGGCGGTGCGGGACGGACTGGCCGATCTCGGCTTCGTCGAGGGCGAGGTGGAGGAGCCGCTGATCGTGCGCCGCCGCGTG
CCGGGCGATGAACTGGTGCTGGTGGCGTCGGCGGACGCGCCCTATGCCGATCTGGACACCCTCTCCGCGCACGACATCGC
CGCCATGCCCTTCGTGCTGCGCGAGCCGGGCTCCGGCACCCGGCAGATGTTCGAGGCCGCCTGCCGCCGGCTGGGGGTGA
AGCCGCAGGCGGTCACCATCGTCTTCGAACTGCCGTCCAACGAGGCGGTGCTGAGCGCGGTGGCGGCCGGGGCAGGGGCG
ACGGTGATCTCGCGGCTGGTGGCGGAGGCGGGCTTGAAGGCGGGGACGCTGAAGGCCCTGCCGCTGGCCCTGCCGCCGCG
CAATTTCTATGTGCTGCATCATGGCGAGCGGGATCGCTCGCGGGCGGCGGAGGCCTTTGTGGGCTTCATCGCGCCGCCCA
AATGA

Upstream 100 bases:

>100_bases
GCCCTCGGCACCGCCTCGTGGCTGTTCATTTCCGCCCTCAGCTTCGGCCTCATCTGGCTGTCGCCCCGGCTGTTCGGGTG
AGGGGCGCGAGAGAGGCGCG

Downstream 100 bases:

>100_bases
AAACGGCCCGCCACCGGGGCGGGCCGTCTGCTCATTGCTGCAACGCGCTCAGGCGAAGGTGACTTCCAGCTCGCCCACGT
TGGCGACGCCGCCCTTCAGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTLDQLKVFVAVADHLHMTRAAEALHMTQSAVSASIAALEQSCGQPLFDRVGRRIELTAAGRLFVGEAQAILKRVAQARD
ALSDLAGLARGTLTLHASQTIANYWLAPRMNAFHAAHPGIRLELGIGNTTQVAAAVRDGLADLGFVEGEVEEPLIVRRRV
PGDELVLVASADAPYADLDTLSAHDIAAMPFVLREPGSGTRQMFEAACRRLGVKPQAVTIVFELPSNEAVLSAVAAGAGA
TVISRLVAEAGLKAGTLKALPLALPPRNFYVLHHGERDRSRAAEAFVGFIAPPK

Sequences:

>Translated_294_residues
MTLDQLKVFVAVADHLHMTRAAEALHMTQSAVSASIAALEQSCGQPLFDRVGRRIELTAAGRLFVGEAQAILKRVAQARD
ALSDLAGLARGTLTLHASQTIANYWLAPRMNAFHAAHPGIRLELGIGNTTQVAAAVRDGLADLGFVEGEVEEPLIVRRRV
PGDELVLVASADAPYADLDTLSAHDIAAMPFVLREPGSGTRQMFEAACRRLGVKPQAVTIVFELPSNEAVLSAVAAGAGA
TVISRLVAEAGLKAGTLKALPLALPPRNFYVLHHGERDRSRAAEAFVGFIAPPK
>Mature_293_residues
TLDQLKVFVAVADHLHMTRAAEALHMTQSAVSASIAALEQSCGQPLFDRVGRRIELTAAGRLFVGEAQAILKRVAQARDA
LSDLAGLARGTLTLHASQTIANYWLAPRMNAFHAAHPGIRLELGIGNTTQVAAAVRDGLADLGFVEGEVEEPLIVRRRVP
GDELVLVASADAPYADLDTLSAHDIAAMPFVLREPGSGTRQMFEAACRRLGVKPQAVTIVFELPSNEAVLSAVAAGAGAT
VISRLVAEAGLKAGTLKALPLALPPRNFYVLHHGERDRSRAAEAFVGFIAPPK

Specific function: Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=294, Percent_Identity=34.3537414965986, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=31.8181818181818, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082132, Length=292, Percent_Identity=27.0547945205479, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=27.536231884058, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789173, Length=283, Percent_Identity=28.2685512367491, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788887, Length=196, Percent_Identity=33.1632653061224, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI145693105, Length=241, Percent_Identity=24.4813278008299, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=262, Percent_Identity=27.8625954198473, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=29.4820717131474, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787806, Length=297, Percent_Identity=26.5993265993266, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788748, Length=295, Percent_Identity=27.7966101694915, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787879, Length=254, Percent_Identity=28.740157480315, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=27.7027027027027, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788296, Length=247, Percent_Identity=26.7206477732794, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=27.2357723577236, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787949, Length=311, Percent_Identity=25.4019292604502, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786401, Length=309, Percent_Identity=24.2718446601942, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787589, Length=169, Percent_Identity=31.9526627218935, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI2367136, Length=279, Percent_Identity=22.9390681003584, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790262, Length=289, Percent_Identity=23.8754325259516, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081978, Length=277, Percent_Identity=27.4368231046931, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788706, Length=126, Percent_Identity=34.1269841269841, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI48994962, Length=145, Percent_Identity=31.7241379310345, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31155; Mature: 31024

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDQLKVFVAVADHLHMTRAAEALHMTQSAVSASIAALEQSCGQPLFDRVGRRIELTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEC
GRLFVGEAQAILKRVAQARDALSDLAGLARGTLTLHASQTIANYWLAPRMNAFHAAHPGI
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHCCCCCHHHCCCCCE
RLELGIGNTTQVAAAVRDGLADLGFVEGEVEEPLIVRRRVPGDELVLVASADAPYADLDT
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCC
LSAHDIAAMPFVLREPGSGTRQMFEAACRRLGVKPQAVTIVFELPSNEAVLSAVAAGAGA
CCCCCHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCHH
TVISRLVAEAGLKAGTLKALPLALPPRNFYVLHHGERDRSRAAEAFVGFIAPPK
HHHHHHHHHCCCCCCCCEECEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLDQLKVFVAVADHLHMTRAAEALHMTQSAVSASIAALEQSCGQPLFDRVGRRIELTAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEC
GRLFVGEAQAILKRVAQARDALSDLAGLARGTLTLHASQTIANYWLAPRMNAFHAAHPGI
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHCCCCCHHHCCCCCE
RLELGIGNTTQVAAAVRDGLADLGFVEGEVEEPLIVRRRVPGDELVLVASADAPYADLDT
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCC
LSAHDIAAMPFVLREPGSGTRQMFEAACRRLGVKPQAVTIVFELPSNEAVLSAVAAGAGA
CCCCCHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCHH
TVISRLVAEAGLKAGTLKALPLALPPRNFYVLHHGERDRSRAAEAFVGFIAPPK
HHHHHHHHHCCCCCCCCEECEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA