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The map label for this gene is bdlA [H]

Identifier: 158422197

GI number: 158422197

Start: 635017

End: 636510

Strand: Direct

Name: bdlA [H]

Synonym: AZC_0573

Alternate gene names: 158422197

Gene position: 635017-636510 (Clockwise)

Preceding gene: 158422194

Following gene: 158422199

Centisome position: 11.83

GC content: 64.79

Gene sequence:

>1494_bases
GTGAGGCGATCCATGTTCGGTGTCGGCAGCCAGTCCGAGGCACTCCTGAAGCTATCCGCCCTGGATCGGGCACAGGCCAT
CATCGAATTCACCCCAACGGGTGAAATCCTCGACGCCAACCAGAATTTCCTCTCGCTCGTCGGCTACGGGCTCAACGAGA
TCAAGGGCAAGCATCACCGCATGTTTGTCGATCCGCGCGAAGCCGAGAGCGCGGAGTATCGCGCTTTCTGGCAGGCGCTC
GGCAAGGGGCAGTATCAGGAGGCGGTCTACCGCCGCATCGGCAAGGGCGGTGCGGTCGTCTGGATCCGCGCCATCTACAA
TCCGCTGATCGACCGTTCGGGCAAGGTGCTGAAGGTGGTGAAATTCGCCACCGACATCACCGAACAGAAGATGCGCTTTG
CCGAACACGAGAGCTTGTTGGCGGCCATTTCCAAGTCGCAGGCGGTCATCCAGTTCGACCTCAAGGGCAACATTCTCGAG
GCCAATCAGAACTTCCTCGACACCATGGGCTACCGGCTGGACGAGATCGTCGGCCGGCACCATTCGATGTTCGTGCCCGA
GCAGATGCGCCAGTCGCCGCAATATGCGGCCTTCTGGGACAACCTGCGCCGCGGGGAATATCAGGCGGCGGAATACAAGC
GCATCGGCAAGGGCGGCCGCGAGGTCTGGATCCAGGCCACCTACAATCCCGTCCTCGATGCGGACGGGGCGGTGTCCAAG
ATCGTCAAGTTCGCCACCGATGTGACCAAGCGCGTTGTGGTGCGCGAACGCCGGGCCGCGGCCTATCGGGAGATCGACGC
GGGTCTCTCCGACATCTCCAGTGAACTGACCGATACCAATTCGCGCGTCGTCTCCGCCTCGGAGGCCACCCAGACGGCGG
CTCACAACATGCAGTCCGTCGCCACCGGCGCGGGCCAACTGGCCGCCTCGGTCGACGACATCAGCCGGCAGGTGCAGCAG
TCGAGCGAACTCTCCGTCGCTGCCGTGGAACAGGGCAATCGCACCAACGAGATCGTGGCGAGCCTCAGCGGTGCGGCCGA
GAAGATCGGCCATGTGGTGGAACTGATCAATTCCATTGCCGCCCAGACCAACCTGCTCGCGCTCAACGCCACCATCGAGG
CCGCGCGTGCCGGCGAGGCCGGCAAGGGCTTCTCGGTCGTCGCGCAGGAGGTGAAGAGCCTCGCCGGCCAGACCTCGAAG
GCGACGAGCGAGATCGCCGCACAGGTCACCGAGGTCCAGGCCGCCACAGGCCAAGCGGTGACGGCGCTTGCGAGCGTTAC
GGAATTCATCACCCAGCTCAACGCCATCGCGGGCAGCATTGCCGATGCGGTGCAGCGCCAGGCGTCCGTGACGCGGGAGG
TCTCCTCCTCCATGCAGACCGTCGCCCACGGCATCGAGGTGGTGAAGCAGGACATGGGCGTGATCGCCAGCGCCACCAGC
CATGTGGAGGCCGCCGCCCGCAAGGTGCGGGAAGCCTCCGCCGCCATCGCCTGA

Upstream 100 bases:

>100_bases
TATTCTGGAAGGTTGTCTCCGGGCGGACGTCCCGCCTCGCGTCCGATGTCGGCCTGAGAGACGTTCGCGTTCCGTGGCCG
CCTGGCCGCGGTGTTCCTGA

Downstream 100 bases:

>100_bases
TCCCGCCGTTCAGGGCGCGCCGAGAAAGCGCGCCCGAGCCTGCCCCACTTCGGAGGCGATGAAATCCGCCGCCGCCCGTA
CGCGGGCAAGGTCGCGCATG

Product: methyl-accepting chemotaxis receptor

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MRRSMFGVGSQSEALLKLSALDRAQAIIEFTPTGEILDANQNFLSLVGYGLNEIKGKHHRMFVDPREAESAEYRAFWQAL
GKGQYQEAVYRRIGKGGAVVWIRAIYNPLIDRSGKVLKVVKFATDITEQKMRFAEHESLLAAISKSQAVIQFDLKGNILE
ANQNFLDTMGYRLDEIVGRHHSMFVPEQMRQSPQYAAFWDNLRRGEYQAAEYKRIGKGGREVWIQATYNPVLDADGAVSK
IVKFATDVTKRVVVRERRAAAYREIDAGLSDISSELTDTNSRVVSASEATQTAAHNMQSVATGAGQLAASVDDISRQVQQ
SSELSVAAVEQGNRTNEIVASLSGAAEKIGHVVELINSIAAQTNLLALNATIEAARAGEAGKGFSVVAQEVKSLAGQTSK
ATSEIAAQVTEVQAATGQAVTALASVTEFITQLNAIAGSIADAVQRQASVTREVSSSMQTVAHGIEVVKQDMGVIASATS
HVEAAARKVREASAAIA

Sequences:

>Translated_497_residues
MRRSMFGVGSQSEALLKLSALDRAQAIIEFTPTGEILDANQNFLSLVGYGLNEIKGKHHRMFVDPREAESAEYRAFWQAL
GKGQYQEAVYRRIGKGGAVVWIRAIYNPLIDRSGKVLKVVKFATDITEQKMRFAEHESLLAAISKSQAVIQFDLKGNILE
ANQNFLDTMGYRLDEIVGRHHSMFVPEQMRQSPQYAAFWDNLRRGEYQAAEYKRIGKGGREVWIQATYNPVLDADGAVSK
IVKFATDVTKRVVVRERRAAAYREIDAGLSDISSELTDTNSRVVSASEATQTAAHNMQSVATGAGQLAASVDDISRQVQQ
SSELSVAAVEQGNRTNEIVASLSGAAEKIGHVVELINSIAAQTNLLALNATIEAARAGEAGKGFSVVAQEVKSLAGQTSK
ATSEIAAQVTEVQAATGQAVTALASVTEFITQLNAIAGSIADAVQRQASVTREVSSSMQTVAHGIEVVKQDMGVIASATS
HVEAAARKVREASAAIA
>Mature_497_residues
MRRSMFGVGSQSEALLKLSALDRAQAIIEFTPTGEILDANQNFLSLVGYGLNEIKGKHHRMFVDPREAESAEYRAFWQAL
GKGQYQEAVYRRIGKGGAVVWIRAIYNPLIDRSGKVLKVVKFATDITEQKMRFAEHESLLAAISKSQAVIQFDLKGNILE
ANQNFLDTMGYRLDEIVGRHHSMFVPEQMRQSPQYAAFWDNLRRGEYQAAEYKRIGKGGREVWIQATYNPVLDADGAVSK
IVKFATDVTKRVVVRERRAAAYREIDAGLSDISSELTDTNSRVVSASEATQTAAHNMQSVATGAGQLAASVDDISRQVQQ
SSELSVAAVEQGNRTNEIVASLSGAAEKIGHVVELINSIAAQTNLLALNATIEAARAGEAGKGFSVVAQEVKSLAGQTSK
ATSEIAAQVTEVQAATGQAVTALASVTEFITQLNAIAGSIADAVQRQASVTREVSSSMQTVAHGIEVVKQDMGVIASATS
HVEAAARKVREASAAIA

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=238, Percent_Identity=31.9327731092437, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367378, Length=211, Percent_Identity=31.7535545023697, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789453, Length=166, Percent_Identity=36.7469879518072, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788194, Length=249, Percent_Identity=30.1204819277108, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788195, Length=242, Percent_Identity=30.1652892561983, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 53529; Mature: 53529

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSMFGVGSQSEALLKLSALDRAQAIIEFTPTGEILDANQNFLSLVGYGLNEIKGKHHR
CCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCEECCCHHHHHHHHCCHHHHCCCCCE
MFVDPREAESAEYRAFWQALGKGQYQEAVYRRIGKGGAVVWIRAIYNPLIDRSGKVLKVV
EEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCHHHHH
KFATDITEQKMRFAEHESLLAAISKSQAVIQFDLKGNILEANQNFLDTMGYRLDEIVGRH
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHCCC
HSMFVPEQMRQSPQYAAFWDNLRRGEYQAAEYKRIGKGGREVWIQATYNPVLDADGAVSK
CCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHH
IVKFATDVTKRVVVRERRAAAYREIDAGLSDISSELTDTNSRVVSASEATQTAAHNMQSV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHH
ATGAGQLAASVDDISRQVQQSSELSVAAVEQGNRTNEIVASLSGAAEKIGHVVELINSIA
HCCHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTNLLALNATIEAARAGEAGKGFSVVAQEVKSLAGQTSKATSEIAAQVTEVQAATGQAV
HHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHH
TALASVTEFITQLNAIAGSIADAVQRQASVTREVSSSMQTVAHGIEVVKQDMGVIASATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVEAAARKVREASAAIA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRSMFGVGSQSEALLKLSALDRAQAIIEFTPTGEILDANQNFLSLVGYGLNEIKGKHHR
CCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCEECCCHHHHHHHHCCHHHHCCCCCE
MFVDPREAESAEYRAFWQALGKGQYQEAVYRRIGKGGAVVWIRAIYNPLIDRSGKVLKVV
EEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCHHHHH
KFATDITEQKMRFAEHESLLAAISKSQAVIQFDLKGNILEANQNFLDTMGYRLDEIVGRH
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHCCC
HSMFVPEQMRQSPQYAAFWDNLRRGEYQAAEYKRIGKGGREVWIQATYNPVLDADGAVSK
CCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHH
IVKFATDVTKRVVVRERRAAAYREIDAGLSDISSELTDTNSRVVSASEATQTAAHNMQSV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHH
ATGAGQLAASVDDISRQVQQSSELSVAAVEQGNRTNEIVASLSGAAEKIGHVVELINSIA
HCCHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTNLLALNATIEAARAGEAGKGFSVVAQEVKSLAGQTSKATSEIAAQVTEVQAATGQAV
HHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHH
TALASVTEFITQLNAIAGSIADAVQRQASVTREVSSSMQTVAHGIEVVKQDMGVIASATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVEAAARKVREASAAIA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]