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The map label for this gene is cobW [H]

Identifier: 158422189

GI number: 158422189

Start: 624684

End: 625850

Strand: Direct

Name: cobW [H]

Synonym: AZC_0565

Alternate gene names: 158422189

Gene position: 624684-625850 (Clockwise)

Preceding gene: 158422188

Following gene: 158422191

Centisome position: 11.63

GC content: 64.61

Gene sequence:

>1167_bases
GTGCGGCGGCCGTATCCGGAAGGGGTGCGGTCGCCGTTGCATGCGCGGGCAGCGGCCCGCACAGGAGACCCCATGGCTGA
GACCGGCTCTGAAAAAATCCCCGTGACTGTGCTCACCGGCTATCTGGGGGCGGGCAAGACCACCTTGCTCAACCGCATCC
TCTCCGAGCCCCACGGGAAGAAGTACGCCGTCATCGTCAACGAGTTCGGCGAGATCGGCATCGACAACGACCTCGTGGTG
GGCGCCGACGAGGAAGTGTTCGAGATGAACAACGGCTGCATCTGCTGCACCGTGCGCGGCGACCTCATCCGCATCATCGA
CGGCCTGCTGCGTCGCAAGGGCCAGTTCGACGGCATCATCGTCGAGACCACCGGCCTTGCCGATCCCGCCCCGGTGGCCC
AGACCTTCTTCGTGGACGAGGAAGTGGGCGCGAAGACCAAGCTCGATGCGGTCGTGACCGTTGCCGACGCCAAGTGGCTG
AGCGACCGCCTGAAGGACGCGCCCGAGGCGAAGAACCAGATCGCCTTCGCGGACGTGATCCTGCTCAACAAGACGGATCT
CGTGAGTGCCGACGAACTGGCCGAGGTGGAGGGCCGCATCCGCGGCATCAACCCCTATGCCCGGCTCTACCGGACGCAGA
AGTCGCAGATCGAGATCGAGAAGGTGCTGAACCAGGGCGCCTTCGACCTCGACCGCATCCTGGCGCTGGAGCCCGCCTTC
CTCGAAGAGGGTGAGGACCACGACCATGACCACACCTGCGGCCCGGACTGCGGCCACGACCACCATCATCACGATCATGG
CCACCACCATGACCATGGGCACGACCATCACCATGGTCACAGCCATGGCGGGCTGAAGCACTATCACGACGAGGAGATGC
AGTCGGTCTCCTTCTCCACCGACAAGCTGCTGGACCCGGACAAGTTCTTCCCCTGGGTGCAGAACGTGGTGGCGACCGAC
GGCGCGAACATCCTGCGCTCCAAGGGTATCCTTGCCTTCAAGGACGATCCGGACCGCTTCGTCTTCCAGGGCGTGCACAT
GATCCTCGACGGCGACCATCAGCGCCCGTGGAAGCCGGACGAGCCCCAGGTGAGCCGCATCGTCTTCATTGGCCGCCACC
TGCCCACCGAGAAGCTGGAAAGCGGCTTTCTCTCCTGCGTGGCGTGA

Upstream 100 bases:

>100_bases
ACATCGACCTGGTGCGATACAATATCCGCCAGCTCTCGGGGGCGCTGACCAAGTGACCTTGCGGCTGTGACCCGGCGCTC
CGGCGCCGGGATGTTCTGAC

Downstream 100 bases:

>100_bases
GATCAGGTCATTCCGAAATGCAGAAGGCCGGCGCGACGCGCCGGCCTTTTTTGTTCGGCAGCTTTTCCGCCCTCAGATGA
AATAGAGCCAGGTCAGCAGG

Product: CobW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRRPYPEGVRSPLHARAAARTGDPMAETGSEKIPVTVLTGYLGAGKTTLLNRILSEPHGKKYAVIVNEFGEIGIDNDLVV
GADEEVFEMNNGCICCTVRGDLIRIIDGLLRRKGQFDGIIVETTGLADPAPVAQTFFVDEEVGAKTKLDAVVTVADAKWL
SDRLKDAPEAKNQIAFADVILLNKTDLVSADELAEVEGRIRGINPYARLYRTQKSQIEIEKVLNQGAFDLDRILALEPAF
LEEGEDHDHDHTCGPDCGHDHHHHDHGHHHDHGHDHHHGHSHGGLKHYHDEEMQSVSFSTDKLLDPDKFFPWVQNVVATD
GANILRSKGILAFKDDPDRFVFQGVHMILDGDHQRPWKPDEPQVSRIVFIGRHLPTEKLESGFLSCVA

Sequences:

>Translated_388_residues
MRRPYPEGVRSPLHARAAARTGDPMAETGSEKIPVTVLTGYLGAGKTTLLNRILSEPHGKKYAVIVNEFGEIGIDNDLVV
GADEEVFEMNNGCICCTVRGDLIRIIDGLLRRKGQFDGIIVETTGLADPAPVAQTFFVDEEVGAKTKLDAVVTVADAKWL
SDRLKDAPEAKNQIAFADVILLNKTDLVSADELAEVEGRIRGINPYARLYRTQKSQIEIEKVLNQGAFDLDRILALEPAF
LEEGEDHDHDHTCGPDCGHDHHHHDHGHHHDHGHDHHHGHSHGGLKHYHDEEMQSVSFSTDKLLDPDKFFPWVQNVVATD
GANILRSKGILAFKDDPDRFVFQGVHMILDGDHQRPWKPDEPQVSRIVFIGRHLPTEKLESGFLSCVA
>Mature_388_residues
MRRPYPEGVRSPLHARAAARTGDPMAETGSEKIPVTVLTGYLGAGKTTLLNRILSEPHGKKYAVIVNEFGEIGIDNDLVV
GADEEVFEMNNGCICCTVRGDLIRIIDGLLRRKGQFDGIIVETTGLADPAPVAQTFFVDEEVGAKTKLDAVVTVADAKWL
SDRLKDAPEAKNQIAFADVILLNKTDLVSADELAEVEGRIRGINPYARLYRTQKSQIEIEKVLNQGAFDLDRILALEPAF
LEEGEDHDHDHTCGPDCGHDHHHHDHGHHHDHGHDHHHGHSHGGLKHYHDEEMQSVSFSTDKLLDPDKFFPWVQNVVATD
GANILRSKGILAFKDDPDRFVFQGVHMILDGDHQRPWKPDEPQVSRIVFIGRHLPTEKLESGFLSCVA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=388, Percent_Identity=35.3092783505155, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI126722884, Length=371, Percent_Identity=35.5795148247978, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI148727351, Length=371, Percent_Identity=35.5795148247978, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI146231952, Length=371, Percent_Identity=35.3099730458221, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI223941776, Length=360, Percent_Identity=34.1666666666667, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI223941779, Length=198, Percent_Identity=46.969696969697, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI119120938, Length=133, Percent_Identity=51.1278195488722, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI87082430, Length=356, Percent_Identity=31.7415730337079, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788499, Length=163, Percent_Identity=34.3558282208589, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324356, Length=228, Percent_Identity=33.7719298245614, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 43101; Mature: 43101

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPYPEGVRSPLHARAAARTGDPMAETGSEKIPVTVLTGYLGAGKTTLLNRILSEPHGK
CCCCCCHHHCCCHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCC
KYAVIVNEFGEIGIDNDLVVGADEEVFEMNNGCICCTVRGDLIRIIDGLLRRKGQFDGII
EEEEEEECCCCCCCCCCEEECCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEE
VETTGLADPAPVAQTFFVDEEVGAKTKLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVI
EEECCCCCCCCCHHEEEECHHCCCCEECCEEEEEHHHHHHHHHHHCCCCHHCCEEEEEEE
LLNKTDLVSADELAEVEGRIRGINPYARLYRTQKSQIEIEKVLNQGAFDLDRILALEPAF
EECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHH
LEEGEDHDHDHTCGPDCGHDHHHHDHGHHHDHGHDHHHGHSHGGLKHYHDEEMQSVSFST
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCH
DKLLDPDKFFPWVQNVVATDGANILRSKGILAFKDDPDRFVFQGVHMILDGDHQRPWKPD
HHCCCCHHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHHHHCCCEEEECCCCCCCCCC
EPQVSRIVFIGRHLPTEKLESGFLSCVA
CCCCEEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRRPYPEGVRSPLHARAAARTGDPMAETGSEKIPVTVLTGYLGAGKTTLLNRILSEPHGK
CCCCCCHHHCCCHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCC
KYAVIVNEFGEIGIDNDLVVGADEEVFEMNNGCICCTVRGDLIRIIDGLLRRKGQFDGII
EEEEEEECCCCCCCCCCEEECCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEE
VETTGLADPAPVAQTFFVDEEVGAKTKLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVI
EEECCCCCCCCCHHEEEECHHCCCCEECCEEEEEHHHHHHHHHHHCCCCHHCCEEEEEEE
LLNKTDLVSADELAEVEGRIRGINPYARLYRTQKSQIEIEKVLNQGAFDLDRILALEPAF
EECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHH
LEEGEDHDHDHTCGPDCGHDHHHHDHGHHHDHGHDHHHGHSHGGLKHYHDEEMQSVSFST
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCH
DKLLDPDKFFPWVQNVVATDGANILRSKGILAFKDDPDRFVFQGVHMILDGDHQRPWKPD
HHCCCCHHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHHHHCCCEEEECCCCCCCCCC
EPQVSRIVFIGRHLPTEKLESGFLSCVA
CCCCEEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]