Click here to switch to the map view.

The map label for this gene is yoeB [H]

Identifier: 158422163

GI number: 158422163

Start: 597240

End: 597506

Strand: Direct

Name: yoeB [H]

Synonym: AZC_0539

Alternate gene names: 158422163

Gene position: 597240-597506 (Clockwise)

Preceding gene: 158422162

Following gene: 158422164

Centisome position: 11.12

GC content: 66.29

Gene sequence:

>267_bases
GTGAAGCTGGTGTTCGCCACCCGCGCCTGGGAGGATTATCTCCATTGGGTGGATGCGGACCGCAACGTGCTGGAGCGGCT
GAACGCCTTGATCGAGGAATGCCGCCGCACGCCCTTTTCCGGCACCGGCCGGCCCGAGCCGCTGAAGGGCGACCTCTCTG
GCTGGTGGTCGCGGCGCATCACCTTGCAGGACCGTCTCGTCTATCGGGTCGCGGGCAAGCCGCCGCACCAGAGCCTGGAG
ATCGCCCAGTGCCGCTATCATTACTGA

Upstream 100 bases:

>100_bases
CGCTGCATCTGCTCTCCTCCCCCGCCAATGCGGCGCGGCTGCGCGAAGGCGTGGCCGAGCTTGAGGCCGGTGGCGGCAGC
GAACGCGACCTTGTGGTGCC

Downstream 100 bases:

>100_bases
GCGCGGGCCGGGCCGCGATCATGAGGACCGCATGACCGAAGTCCTCTTCTACCATCTGGAGCGCCGGCCGCTGGAGGATG
CGCTGCCGGTGCTGCTGGAG

Product: addiction module toxin

Products: NA

Alternate protein names: Endoribonuclease YoeB; Putative mRNA interferase YoeB [H]

Number of amino acids: Translated: 88; Mature: 88

Protein sequence:

>88_residues
MKLVFATRAWEDYLHWVDADRNVLERLNALIEECRRTPFSGTGRPEPLKGDLSGWWSRRITLQDRLVYRVAGKPPHQSLE
IAQCRYHY

Sequences:

>Translated_88_residues
MKLVFATRAWEDYLHWVDADRNVLERLNALIEECRRTPFSGTGRPEPLKGDLSGWWSRRITLQDRLVYRVAGKPPHQSLE
IAQCRYHY
>Mature_88_residues
MKLVFATRAWEDYLHWVDADRNVLERLNALIEECRRTPFSGTGRPEPLKGDLSGWWSRRITLQDRLVYRVAGKPPHQSLE
IAQCRYHY

Specific function: Part of a toxin-antitoxin (TA) module. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides [H]

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=88, Percent_Identity=53.4090909090909, Blast_Score=103, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10441; Mature: 10441

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVFATRAWEDYLHWVDADRNVLERLNALIEECRRTPFSGTGRPEPLKGDLSGWWSRRI
CCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCE
TLQDRLVYRVAGKPPHQSLEIAQCRYHY
EHHHHEEEEECCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MKLVFATRAWEDYLHWVDADRNVLERLNALIEECRRTPFSGTGRPEPLKGDLSGWWSRRI
CCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCE
TLQDRLVYRVAGKPPHQSLEIAQCRYHY
EHHHHEEEEECCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10517584; 12000953 [H]