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The map label for this gene is dnaB [H]

Identifier: 158422154

GI number: 158422154

Start: 587437

End: 588915

Strand: Direct

Name: dnaB [H]

Synonym: AZC_0530

Alternate gene names: 158422154

Gene position: 587437-588915 (Clockwise)

Preceding gene: 158422153

Following gene: 158422155

Centisome position: 10.94

GC content: 65.99

Gene sequence:

>1479_bases
ATGCTCGATCTTGCCGCGTCGAAGGAGGACCTGCCCGCCTATCGCCAGCCGCCCCACAATGTGGAGGCCGAGCAGGCGCT
GCTGGGCGCGATCCTCGTCAATAACGAGGCCTTCTATCGCGTCTCCGACTTCCTGAAGGCGGAGCATTTCTACGAGCCCC
TGCACGGCCGCATCTATGATCTGACCGGTTCGCTGATCCGCGCCGGCAAGATCGCGACGCCCATCACGCTGAAGACCTTC
CTCCCGGCGGACCTGGACGTCGGCGGCCTCAACGGCCCGCAATATCTCGCCCGCCTCGCGGCGGAGGCGACCACCATCAT
CAATGCCGAGGACTACGGCCGGGCCATCTATGACCTCTCGGTGCGGCGCGAGCTGATCCGTATCGGCGAGGAGATCGTCA
ACGATGCCTATGACGCGCCCATCGAGGCGCAGCCGCAGGACCAGATCGAGGAAGCGGAAAAGCGCCTCTACGCCATCGCC
GAATCCGGCCGCTACGACGGCGGCTTCGTGCGCTTCGGCGATGCACTGCGCGAATCGGTGGACATGGCGAGCCGCGCCTT
CCAGCGCGAGGGCCACCTCTCCGGCATCGCCTCCGGGCTCGACGATCTCGATGCCCAGATGGGCGGCCTCCAGCCCTCGG
ATTTGATCATCCTCGCGGGGCGCCCGGCCATGGGCAAGACCTCGCTCGCCACCAACATCGCCTACAACATCGCCTCCGCC
TATCGCGGCGAGCAGAAGCCGGACGGCTCCATCGAGGCGGTGTCCGGCGGCGTGGTGGGCTTCTTCTCGCTCGAAATGTC
GTCCGAGCAGCTCGCCACCCGTATCCTGGCCGAGCAGGCGGAGATCGCCTCCTACAAGATCCGCCGCGGCGACATCTCGG
AAAGCGAGTTCTCCAAGCTCGCCGCCGCCGCCCAGTCCATGCAGGTAGTGCCGCTGTATATCGACGACACCGGCGGCATC
TCCATCGCCCAGCTCGTGGCCCGCGCCCGCCGCCTCAAGCGCCAGCGCGGCCTCGACTTCATGGTGGTGGACTATCTCCA
GCTGCTGTCGGGCTCGGGCAAGGCCAGCTCCAACCGCGTGCAGGAAATCACCGAGATCACCACCGGCCTCAAGGCGCTGG
CCAAGGAGCTGAACGTGCCCATCATGGCGCTGTCCCAGCTCTCCCGTCAGGTGGAAAGCCGCGACGACAAGCGCCCCCAG
CTCTCGGACCTTCGCGAATCCGGCTCCATCGAGCAGGACGCCGACGTGGTCATGTTCGTGTATCGCGAGGAATATTACCT
CAAGAGCCGCGAGCCCAAGCCCGGAACCGAGGAATGGTTCAAGTGGGAGACCGACATGAAGGCCTGCGAGGCGATGGCTG
AGATCATCGTGGGCAAGCAGCGTCACGGTCCCACGGGCACGGTGAAGGTGCACTTCGAGGCGCAGTTCACCCGCTTCGGC
AATCTCGCCCGCGAGGACCGCTTCCCCGACCGTCACTGA

Upstream 100 bases:

>100_bases
CCCACAATTCTTCACACGGGACGGCAGGCGCATCTCGTCCGCAAAAGCCGGCTACGATCTGGTACATCTGGGAGCCGCCC
ACCCAGACAGAACGTGACCG

Downstream 100 bases:

>100_bases
CGCGGCGCCGCGCCCGGCCCGCCGGGTGCGACAGAGTGAATCAGATGGCGGTTGCGGTGAGGCAAGGCTCGACAGCGGCG
GCGCGGCGCAGCGATGATTC

Product: DnaB helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLDLAASKEDLPAYRQPPHNVEAEQALLGAILVNNEAFYRVSDFLKAEHFYEPLHGRIYDLTGSLIRAGKIATPITLKTF
LPADLDVGGLNGPQYLARLAAEATTIINAEDYGRAIYDLSVRRELIRIGEEIVNDAYDAPIEAQPQDQIEEAEKRLYAIA
ESGRYDGGFVRFGDALRESVDMASRAFQREGHLSGIASGLDDLDAQMGGLQPSDLIILAGRPAMGKTSLATNIAYNIASA
YRGEQKPDGSIEAVSGGVVGFFSLEMSSEQLATRILAEQAEIASYKIRRGDISESEFSKLAAAAQSMQVVPLYIDDTGGI
SIAQLVARARRLKRQRGLDFMVVDYLQLLSGSGKASSNRVQEITEITTGLKALAKELNVPIMALSQLSRQVESRDDKRPQ
LSDLRESGSIEQDADVVMFVYREEYYLKSREPKPGTEEWFKWETDMKACEAMAEIIVGKQRHGPTGTVKVHFEAQFTRFG
NLAREDRFPDRH

Sequences:

>Translated_492_residues
MLDLAASKEDLPAYRQPPHNVEAEQALLGAILVNNEAFYRVSDFLKAEHFYEPLHGRIYDLTGSLIRAGKIATPITLKTF
LPADLDVGGLNGPQYLARLAAEATTIINAEDYGRAIYDLSVRRELIRIGEEIVNDAYDAPIEAQPQDQIEEAEKRLYAIA
ESGRYDGGFVRFGDALRESVDMASRAFQREGHLSGIASGLDDLDAQMGGLQPSDLIILAGRPAMGKTSLATNIAYNIASA
YRGEQKPDGSIEAVSGGVVGFFSLEMSSEQLATRILAEQAEIASYKIRRGDISESEFSKLAAAAQSMQVVPLYIDDTGGI
SIAQLVARARRLKRQRGLDFMVVDYLQLLSGSGKASSNRVQEITEITTGLKALAKELNVPIMALSQLSRQVESRDDKRPQ
LSDLRESGSIEQDADVVMFVYREEYYLKSREPKPGTEEWFKWETDMKACEAMAEIIVGKQRHGPTGTVKVHFEAQFTRFG
NLAREDRFPDRH
>Mature_492_residues
MLDLAASKEDLPAYRQPPHNVEAEQALLGAILVNNEAFYRVSDFLKAEHFYEPLHGRIYDLTGSLIRAGKIATPITLKTF
LPADLDVGGLNGPQYLARLAAEATTIINAEDYGRAIYDLSVRRELIRIGEEIVNDAYDAPIEAQPQDQIEEAEKRLYAIA
ESGRYDGGFVRFGDALRESVDMASRAFQREGHLSGIASGLDDLDAQMGGLQPSDLIILAGRPAMGKTSLATNIAYNIASA
YRGEQKPDGSIEAVSGGVVGFFSLEMSSEQLATRILAEQAEIASYKIRRGDISESEFSKLAAAAQSMQVVPLYIDDTGGI
SIAQLVARARRLKRQRGLDFMVVDYLQLLSGSGKASSNRVQEITEITTGLKALAKELNVPIMALSQLSRQVESRDDKRPQ
LSDLRESGSIEQDADVVMFVYREEYYLKSREPKPGTEEWFKWETDMKACEAMAEIIVGKQRHGPTGTVKVHFEAQFTRFG
NLAREDRFPDRH

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=471, Percent_Identity=38.8535031847134, Blast_Score=299, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 54420; Mature: 54420

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLAASKEDLPAYRQPPHNVEAEQALLGAILVNNEAFYRVSDFLKAEHFYEPLHGRIYD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCEEEE
LTGSLIRAGKIATPITLKTFLPADLDVGGLNGPQYLARLAAEATTIINAEDYGRAIYDLS
CHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEECCHHHCHHHHHHH
VRRELIRIGEEIVNDAYDAPIEAQPQDQIEEAEKRLYAIAESGRYDGGFVRFGDALRESV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
DMASRAFQREGHLSGIASGLDDLDAQMGGLQPSDLIILAGRPAMGKTSLATNIAYNIASA
HHHHHHHHHCCCHHHHHHCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YRGEQKPDGSIEAVSGGVVGFFSLEMSSEQLATRILAEQAEIASYKIRRGDISESEFSKL
HCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHH
AAAAQSMQVVPLYIDDTGGISIAQLVARARRLKRQRGLDFMVVDYLQLLSGSGKASSNRV
HHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHH
QEITEITTGLKALAKELNVPIMALSQLSRQVESRDDKRPQLSDLRESGSIEQDADVVMFV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEEE
YREEYYLKSREPKPGTEEWFKWETDMKACEAMAEIIVGKQRHGPTGTVKVHFEAQFTRFG
EEHHHHHCCCCCCCCCHHHHEECHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHC
NLAREDRFPDRH
CHHHHCCCCCCC
>Mature Secondary Structure
MLDLAASKEDLPAYRQPPHNVEAEQALLGAILVNNEAFYRVSDFLKAEHFYEPLHGRIYD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCEEEE
LTGSLIRAGKIATPITLKTFLPADLDVGGLNGPQYLARLAAEATTIINAEDYGRAIYDLS
CHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEECCHHHCHHHHHHH
VRRELIRIGEEIVNDAYDAPIEAQPQDQIEEAEKRLYAIAESGRYDGGFVRFGDALRESV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
DMASRAFQREGHLSGIASGLDDLDAQMGGLQPSDLIILAGRPAMGKTSLATNIAYNIASA
HHHHHHHHHCCCHHHHHHCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YRGEQKPDGSIEAVSGGVVGFFSLEMSSEQLATRILAEQAEIASYKIRRGDISESEFSKL
HCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHH
AAAAQSMQVVPLYIDDTGGISIAQLVARARRLKRQRGLDFMVVDYLQLLSGSGKASSNRV
HHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHH
QEITEITTGLKALAKELNVPIMALSQLSRQVESRDDKRPQLSDLRESGSIEQDADVVMFV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEEE
YREEYYLKSREPKPGTEEWFKWETDMKACEAMAEIIVGKQRHGPTGTVKVHFEAQFTRFG
EEHHHHHCCCCCCCCCHHHHEECHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHC
NLAREDRFPDRH
CHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA