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The map label for this gene is ruvB

Identifier: 158422143

GI number: 158422143

Start: 574449

End: 575501

Strand: Direct

Name: ruvB

Synonym: AZC_0519

Alternate gene names: 158422143

Gene position: 574449-575501 (Clockwise)

Preceding gene: 158422142

Following gene: 158422144

Centisome position: 10.7

GC content: 70.37

Gene sequence:

>1053_bases
ATGGTGGCACAAGGCGGCATGGCTCCCCGTCTGATGACCGCCGATTCCCGTCCCGAGGACGATGCCGACGCGACCTTGCG
TCCGCAGCGGCTCGCCGATTTCGTCGGGCAGGCGCAAGCCCGCGCCAATCTGGAGGTCTTCATCCAGGCCGCCCGCGCGC
GGGGCGAGGCGCTCGACCATGTGCTGTTCGTTGGCCCGCCCGGCCTCGGCAAGACGACGCTCGCCCAGATCATGGCCCGC
GAGATGGGGGTGGGCTTCCGCTCCACGTCCGGCCCGGTGATCGCGAAGGCCGGCGACCTCGCGGCCATCCTGACCAATCT
CGAAGAGCGCGACGTGCTCTTCATCGACGAGATCCACCGCCTTGCGCCGCAGGTGGAGGAAATCCTCTATCCGGCCATGG
AGGATTACGAGCTCGATCTCGTCATCGGCGAGGGGCCGGCGGCCCGCTCTGTGAAGATCTCGCTGCCGAAGTTCACGCTG
GTGGGCGCCACCACCCGTTCGGGCCTGCTCACCACGCCGCTGCGCGACCGCTTCGGCATTCCCGTGCGGCTGGTCTTCTA
TACGCTGGAAGAGCTGGAATACATCGTCACCCGCGGCGCCCGCCTGCTCGGCATCGGCATCGTGCCGGAAGGCGCGCGGG
AAATCGCCCGCCGGGCGCGCGGCACGCCCCGCATCGCGGGCCGCCTGCTGCGCCGGGTGCGCGACTTCGCCCAGTTCGCC
GGGGCCGAGGCCATCGACCGGGCCATCGCCGATCGGGCGCTGATGGCGCTCGACGTCGACGCCATGGGCCTCGACACCAT
GGACCGGCGCTACCTCACGGTGATCGCGCAGCATTATGGCGGCGGGCCGGTGGGCGTGGAGACGCTGGCCGCCGCGCTCT
CCGAGCCGCGCGACGCCATCGAGGAGATCGTCGAGCCCTATCTGGTGCAGCAGGGTTTCGTGCAGCGCACGCCGCGCGGG
CGGATGCTCACCTCCGGCGCCTTCCGGCATCTGGGCCTTGCCGAGCCGCAGCGCCCGCCGAGCGCCTTGCCCCTGTTTGA
TGAAGGTGATTAG

Upstream 100 bases:

>100_bases
CGCTCTCGGAGCGGCAGGGGCACTGGCTAGCGGCGCTGAAGGCCGAGCGGCTCTGAGGCGCACACGGGCGGCCGTTCAAG
CGACTGGAAACCGGCCGCGC

Downstream 100 bases:

>100_bases
AGACGCGCGAAAAGCGTGAGCTTGAGAACGTGTCCCGCTTGGTGCCTTCCCCCTCCCCAACCCTCCCCTAGCCAAGCGGG
AGAGGGGGCCTGTCGTGATG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MVAQGGMAPRLMTADSRPEDDADATLRPQRLADFVGQAQARANLEVFIQAARARGEALDHVLFVGPPGLGKTTLAQIMAR
EMGVGFRSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPQVEEILYPAMEDYELDLVIGEGPAARSVKISLPKFTL
VGATTRSGLLTTPLRDRFGIPVRLVFYTLEELEYIVTRGARLLGIGIVPEGAREIARRARGTPRIAGRLLRRVRDFAQFA
GAEAIDRAIADRALMALDVDAMGLDTMDRRYLTVIAQHYGGGPVGVETLAAALSEPRDAIEEIVEPYLVQQGFVQRTPRG
RMLTSGAFRHLGLAEPQRPPSALPLFDEGD

Sequences:

>Translated_350_residues
MVAQGGMAPRLMTADSRPEDDADATLRPQRLADFVGQAQARANLEVFIQAARARGEALDHVLFVGPPGLGKTTLAQIMAR
EMGVGFRSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPQVEEILYPAMEDYELDLVIGEGPAARSVKISLPKFTL
VGATTRSGLLTTPLRDRFGIPVRLVFYTLEELEYIVTRGARLLGIGIVPEGAREIARRARGTPRIAGRLLRRVRDFAQFA
GAEAIDRAIADRALMALDVDAMGLDTMDRRYLTVIAQHYGGGPVGVETLAAALSEPRDAIEEIVEPYLVQQGFVQRTPRG
RMLTSGAFRHLGLAEPQRPPSALPLFDEGD
>Mature_350_residues
MVAQGGMAPRLMTADSRPEDDADATLRPQRLADFVGQAQARANLEVFIQAARARGEALDHVLFVGPPGLGKTTLAQIMAR
EMGVGFRSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPQVEEILYPAMEDYELDLVIGEGPAARSVKISLPKFTL
VGATTRSGLLTTPLRDRFGIPVRLVFYTLEELEYIVTRGARLLGIGIVPEGAREIARRARGTPRIAGRLLRRVRDFAQFA
GAEAIDRAIADRALMALDVDAMGLDTMDRRYLTVIAQHYGGGPVGVETLAAALSEPRDAIEEIVEPYLVQQGFVQRTPRG
RMLTSGAFRHLGLAEPQRPPSALPLFDEGD

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=333, Percent_Identity=62.1621621621622, Blast_Score=417, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_AZOC5 (A8IMA7)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001523435.1
- ProteinModelPortal:   A8IMA7
- SMR:   A8IMA7
- GeneID:   5691352
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_0519
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   ACAU438753:AZC_0519-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00819
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38042; Mature: 38042

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAQGGMAPRLMTADSRPEDDADATLRPQRLADFVGQAQARANLEVFIQAARARGEALDH
CCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCE
VLFVGPPGLGKTTLAQIMAREMGVGFRSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHR
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHCCCCCCCHHHHHHHH
LAPQVEEILYPAMEDYELDLVIGEGPAARSVKISLPKFTLVGATTRSGLLTTPLRDRFGI
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEECCCHHHCCC
PVRLVFYTLEELEYIVTRGARLLGIGIVPEGAREIARRARGTPRIAGRLLRRVRDFAQFA
CHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GAEAIDRAIADRALMALDVDAMGLDTMDRRYLTVIAQHYGGGPVGVETLAAALSEPRDAI
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHH
EEIVEPYLVQQGFVQRTPRGRMLTSGAFRHLGLAEPQRPPSALPLFDEGD
HHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVAQGGMAPRLMTADSRPEDDADATLRPQRLADFVGQAQARANLEVFIQAARARGEALDH
CCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCE
VLFVGPPGLGKTTLAQIMAREMGVGFRSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHR
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHCCCCCCCHHHHHHHH
LAPQVEEILYPAMEDYELDLVIGEGPAARSVKISLPKFTLVGATTRSGLLTTPLRDRFGI
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEECCCHHHCCC
PVRLVFYTLEELEYIVTRGARLLGIGIVPEGAREIARRARGTPRIAGRLLRRVRDFAQFA
CHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GAEAIDRAIADRALMALDVDAMGLDTMDRRYLTVIAQHYGGGPVGVETLAAALSEPRDAI
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHH
EEIVEPYLVQQGFVQRTPRGRMLTSGAFRHLGLAEPQRPPSALPLFDEGD
HHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA