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The map label for this gene is ruvA

Identifier: 158422139

GI number: 158422139

Start: 572376

End: 572996

Strand: Direct

Name: ruvA

Synonym: AZC_0515

Alternate gene names: 158422139

Gene position: 572376-572996 (Clockwise)

Preceding gene: 158422138

Following gene: 158422142

Centisome position: 10.66

GC content: 69.4

Gene sequence:

>621_bases
ATGATCGGCAAGTTGAAGGGGACCGTGGACAGCTTCGGCGAGGACCACCTCATCCTCGATGTCCATGGGGTCGGCTATCT
CGTCCATTGCTCCGGACGTACGTTGCAGGCGCTGCCGCGCGTGGGCGAGGCGGCGGTGCTGTTCATCGAGACCCATGTCC
GCGAGGATCAGATCCGGCTGTTCGGCTTCGTCACCGAGGCGGAGCGCGAGTGGTTCCGGCTGCTTCAGGGCATTCAGGGC
ATCGGAACGAAGACCGCGCTCGCCATCCTCTCCACGCTCAAGCCCTCCGACCTCGCGCAGGCGGTGGCGCTGGGCGACAA
GACGGCGCTCGCCCGGGCCAATGGCGTCGGCCCCCGCGTCGCCACCCGCATCGTGACCGAGCTGAAGGACAAGGTGCCCG
CCTTCACCGCCGCCGATCCGGGCCTTGCCCGCCTTGCAGCGGATGTGGAGGCGACGGAAGCGGCCGGCGGGGCGCTCGCC
GATGCGGTCTCGGCCCTCGTCAATCTCGGCTATGGGCAGGCGCAGGCGCACACCGCCATCGCCGCTGCCGGCCGCAAGGC
GGGCGAGGACGCCACCACCGAGACCCTCATCCGCCTCGGGCTGAAGGAACTGGCGAAGTAG

Upstream 100 bases:

>100_bases
GTGGGGCCAGTTGCACATGGTGCGCACGGGCCTTGGCCTGCTCGCCACCCTCATTTTCCTCTGGGGCACGCTCGGCTGAG
GCCGGGCCGGACAGGACGCG

Downstream 100 bases:

>100_bases
GCTCAGCCCGGCAGGGGCAGTTCCGTGAGCGGCAGCAGCCGCGAATCCGCCAGCGCGGCCGTGCGGTGGCCCATGACCTT
TCGATAGGCCGGACCGTTGG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIGKLKGTVDSFGEDHLILDVHGVGYLVHCSGRTLQALPRVGEAAVLFIETHVREDQIRLFGFVTEAEREWFRLLQGIQG
IGTKTALAILSTLKPSDLAQAVALGDKTALARANGVGPRVATRIVTELKDKVPAFTAADPGLARLAADVEATEAAGGALA
DAVSALVNLGYGQAQAHTAIAAAGRKAGEDATTETLIRLGLKELAK

Sequences:

>Translated_206_residues
MIGKLKGTVDSFGEDHLILDVHGVGYLVHCSGRTLQALPRVGEAAVLFIETHVREDQIRLFGFVTEAEREWFRLLQGIQG
IGTKTALAILSTLKPSDLAQAVALGDKTALARANGVGPRVATRIVTELKDKVPAFTAADPGLARLAADVEATEAAGGALA
DAVSALVNLGYGQAQAHTAIAAAGRKAGEDATTETLIRLGLKELAK
>Mature_206_residues
MIGKLKGTVDSFGEDHLILDVHGVGYLVHCSGRTLQALPRVGEAAVLFIETHVREDQIRLFGFVTEAEREWFRLLQGIQG
IGTKTALAILSTLKPSDLAQAVALGDKTALARANGVGPRVATRIVTELKDKVPAFTAADPGLARLAADVEATEAAGGALA
DAVSALVNLGYGQAQAHTAIAAAGRKAGEDATTETLIRLGLKELAK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=206, Percent_Identity=36.4077669902913, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_AZOC5 (A8IM99)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001523431.1
- ProteinModelPortal:   A8IM99
- SMR:   A8IM99
- GeneID:   5688026
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_0515
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   ACAU438753:AZC_0515-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21501; Mature: 21501

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLKGTVDSFGEDHLILDVHGVGYLVHCSGRTLQALPRVGEAAVLFIETHVREDQIRL
CCCCCCCCHHHCCCCEEEEEEECCEEEEEECCCHHHHHCCCCCEEEEEEEECCCCCHHHH
FGFVTEAEREWFRLLQGIQGIGTKTALAILSTLKPSDLAQAVALGDKTALARANGVGPRV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCHHH
ATRIVTELKDKVPAFTAADPGLARLAADVEATEAAGGALADAVSALVNLGYGQAQAHTAI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHH
AAAGRKAGEDATTETLIRLGLKELAK
HHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLKGTVDSFGEDHLILDVHGVGYLVHCSGRTLQALPRVGEAAVLFIETHVREDQIRL
CCCCCCCCHHHCCCCEEEEEEECCEEEEEECCCHHHHHCCCCCEEEEEEEECCCCCHHHH
FGFVTEAEREWFRLLQGIQGIGTKTALAILSTLKPSDLAQAVALGDKTALARANGVGPRV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCHHH
ATRIVTELKDKVPAFTAADPGLARLAADVEATEAAGGALADAVSALVNLGYGQAQAHTAI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHH
AAAGRKAGEDATTETLIRLGLKELAK
HHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA