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The map label for this gene is 158422125

Identifier: 158422125

GI number: 158422125

Start: 558484

End: 559509

Strand: Reverse

Name: 158422125

Synonym: AZC_0501

Alternate gene names: NA

Gene position: 559509-558484 (Counterclockwise)

Preceding gene: 158422126

Following gene: 158422124

Centisome position: 10.42

GC content: 68.03

Gene sequence:

>1026_bases
ATGAACGCTGAACTCGAGACGATCGCGCAGAAGATGGTGTCCGACGGCAAGGGCATTCTTGCCGCTGACGAGAGCACCAG
CACGATCAAGAAGCGGTTCGACGCCATCGGTGTCGAGTCCACCGAGGAAAACCGTCGCGATTACCGCGAGTTGCTGTTCC
GTTCGGACGAGGCGATGAAGGAGTACATCTCCGGCGTCATCCTGTTCGACGAGACCCTGCGCCAGAAGGCCAAGGACGGC
ACCCCGCTCGTCAGCCTCATCCAGCAGGCCGGCTCCATCCCCGGCATCAAGGTGGACGCCGGTGCCAAGCCCATGGCGCT
GTTCCCGGGCGAGACCATCACGGAAGGCCTCGACGGCCTCGCCGGCCGCCTGAAGGAGTATTACGACCTCGGCGCCCGCT
TCGCGAAGTGGCGCGCGGTGATCGATATCGGCGCCGGTATCCCCACCCCCGGTGCCGTTGCCGCCAACGCGCACGCCCTG
GCCCGCTATGCGGCCCTGTGCCAGGAAGCCAACATCGTCCCGATCGTCGAGCCGGAAGTGCTCATGGACGGCGACCACGG
CATCGAGCGCTGCTACGAAGTGACGGAATACGTCCTGCGCGTGGTGTTCGGCGAGCTCTACCAGCAGCGCGTCGCCCTTG
AGGGCATGGTGCTGAAGCCGAACATGGTCGTCCCCGGCAAGAAGGCCCGCACCCAGGCCTCCGTCGCCCAGGTGGCCGAG
CAGACCGTGCGCGTGCTGAAGGCCACCGTCCCGGCGGCGGTGCCTGGCATCGCCTTCCTCTCCGGCGGCCAGTCGGACGA
GGACGCCACCGCCCACCTCGACGCCATGGTGAAGCTCGGCAACCTGCCGTGGAAGCTCACCTATTCCTACGGCCGCGCCC
TCCAGGCCGCGCCGCAGAAGGCGTGGTCCGGCAAGGCCGAGAACGTGGCCGCCGCGCAGGCCGCCTTCACGCACCGCGCC
CGCATGAACTCGCTGGCGGCGCTGGGCCGCTGGAGCGCCGAGCAGGAAGCCAAGAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
CGGGGGTCGAAGCGCTGCGGCGCTGAGACCTCGGTGTTATACTCAACCCATAAAGTGCAGGCATCAGCCGCAGGGGCGGC
TCCAAGGGGATAGGCAGACC

Downstream 100 bases:

>100_bases
TCGGCCCCTTGCGCCTTTATCCGCGTTGAGAGAGCCCGCCGTCCCGCGAGGGACCGGCGGGCTCTTGCGTTCTCCCCCCG
GCCCGCCTAGAGCCTGATGC

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNAELETIAQKMVSDGKGILAADESTSTIKKRFDAIGVESTEENRRDYRELLFRSDEAMKEYISGVILFDETLRQKAKDG
TPLVSLIQQAGSIPGIKVDAGAKPMALFPGETITEGLDGLAGRLKEYYDLGARFAKWRAVIDIGAGIPTPGAVAANAHAL
ARYAALCQEANIVPIVEPEVLMDGDHGIERCYEVTEYVLRVVFGELYQQRVALEGMVLKPNMVVPGKKARTQASVAQVAE
QTVRVLKATVPAAVPGIAFLSGGQSDEDATAHLDAMVKLGNLPWKLTYSYGRALQAAPQKAWSGKAENVAAAQAAFTHRA
RMNSLAALGRWSAEQEAKKAA

Sequences:

>Translated_341_residues
MNAELETIAQKMVSDGKGILAADESTSTIKKRFDAIGVESTEENRRDYRELLFRSDEAMKEYISGVILFDETLRQKAKDG
TPLVSLIQQAGSIPGIKVDAGAKPMALFPGETITEGLDGLAGRLKEYYDLGARFAKWRAVIDIGAGIPTPGAVAANAHAL
ARYAALCQEANIVPIVEPEVLMDGDHGIERCYEVTEYVLRVVFGELYQQRVALEGMVLKPNMVVPGKKARTQASVAQVAE
QTVRVLKATVPAAVPGIAFLSGGQSDEDATAHLDAMVKLGNLPWKLTYSYGRALQAAPQKAWSGKAENVAAAQAAFTHRA
RMNSLAALGRWSAEQEAKKAA
>Mature_341_residues
MNAELETIAQKMVSDGKGILAADESTSTIKKRFDAIGVESTEENRRDYRELLFRSDEAMKEYISGVILFDETLRQKAKDG
TPLVSLIQQAGSIPGIKVDAGAKPMALFPGETITEGLDGLAGRLKEYYDLGARFAKWRAVIDIGAGIPTPGAVAANAHAL
ARYAALCQEANIVPIVEPEVLMDGDHGIERCYEVTEYVLRVVFGELYQQRVALEGMVLKPNMVVPGKKARTQASVAQVAE
QTVRVLKATVPAAVPGIAFLSGGQSDEDATAHLDAMVKLGNLPWKLTYSYGRALQAAPQKAWSGKAENVAAAQAAFTHRA
RMNSLAALGRWSAEQEAKKAA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=339, Percent_Identity=53.0973451327434, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI34577110, Length=339, Percent_Identity=53.0973451327434, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI4557305, Length=339, Percent_Identity=53.0973451327434, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI193794814, Length=339, Percent_Identity=53.0973451327434, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI4885063, Length=339, Percent_Identity=51.0324483775811, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI40354205, Length=330, Percent_Identity=51.5151515151515, Blast_Score=322, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI25150450, Length=331, Percent_Identity=51.6616314199396, Blast_Score=340, Evalue=9e-94,
Organism=Caenorhabditis elegans, GI71983985, Length=330, Percent_Identity=52.4242424242424, Blast_Score=334, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI71983990, Length=231, Percent_Identity=50.2164502164502, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI221459619, Length=334, Percent_Identity=52.3952095808383, Blast_Score=335, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24650288, Length=334, Percent_Identity=52.3952095808383, Blast_Score=335, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24650282, Length=332, Percent_Identity=52.4096385542169, Blast_Score=333, Evalue=8e-92,
Organism=Drosophila melanogaster, GI24650280, Length=332, Percent_Identity=52.4096385542169, Blast_Score=333, Evalue=8e-92,
Organism=Drosophila melanogaster, GI24650278, Length=332, Percent_Identity=52.4096385542169, Blast_Score=333, Evalue=8e-92,
Organism=Drosophila melanogaster, GI45553577, Length=332, Percent_Identity=52.4096385542169, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24650304, Length=333, Percent_Identity=44.1441441441441, Blast_Score=300, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36702; Mature: 36702

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAELETIAQKMVSDGKGILAADESTSTIKKRFDAIGVESTEENRRDYRELLFRSDEAMK
CCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHH
EYISGVILFDETLRQKAKDGTPLVSLIQQAGSIPGIKVDAGAKPMALFPGETITEGLDGL
HHHCCCCEEHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCCEEECCCCHHHHHHHHH
AGRLKEYYDLGARFAKWRAVIDIGAGIPTPGAVAANAHALARYAALCQEANIVPIVEPEV
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHH
LMDGDHGIERCYEVTEYVLRVVFGELYQQRVALEGMVLKPNMVVPGKKARTQASVAQVAE
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEECCCCHHHHHHHHHHHHH
QTVRVLKATVPAAVPGIAFLSGGQSDEDATAHLDAMVKLGNLPWKLTYSYGRALQAAPQK
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
AWSGKAENVAAAQAAFTHRARMNSLAALGRWSAEQEAKKAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MNAELETIAQKMVSDGKGILAADESTSTIKKRFDAIGVESTEENRRDYRELLFRSDEAMK
CCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHH
EYISGVILFDETLRQKAKDGTPLVSLIQQAGSIPGIKVDAGAKPMALFPGETITEGLDGL
HHHCCCCEEHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCCCCEEECCCCHHHHHHHHH
AGRLKEYYDLGARFAKWRAVIDIGAGIPTPGAVAANAHALARYAALCQEANIVPIVEPEV
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHH
LMDGDHGIERCYEVTEYVLRVVFGELYQQRVALEGMVLKPNMVVPGKKARTQASVAQVAE
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEECCCCHHHHHHHHHHHHH
QTVRVLKATVPAAVPGIAFLSGGQSDEDATAHLDAMVKLGNLPWKLTYSYGRALQAAPQK
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
AWSGKAENVAAAQAAFTHRARMNSLAALGRWSAEQEAKKAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]