Click here to switch to the map view.

The map label for this gene is qor [H]

Identifier: 158422114

GI number: 158422114

Start: 548141

End: 549289

Strand: Reverse

Name: qor [H]

Synonym: AZC_0490

Alternate gene names: 158422114

Gene position: 549289-548141 (Counterclockwise)

Preceding gene: 158422117

Following gene: 158422113

Centisome position: 10.23

GC content: 68.76

Gene sequence:

>1149_bases
GTGCTCCGGCATTTTCACCCGAGGCCGGATGGGTTACCAGAGCGCCGAAGGCCGACATCCACCGGCCAGCCGCCGCGCGC
CAGCGCGGAAGGCGCCTCAGGCGCACGGCATCATCCCTCGCCTTCCCCTTTTCGAGGAGCCGCCATGACCACGCCCCTGC
CCGCCACCATGACCGCCATCACCATCCCGACCCCCGGCGGCCCGGAGGCCCTTGTGCCGGGCGAGCGTCCGGTGCCGCAG
CCGGTGAAGGGTGAATTGCTGGTGAAGGTGAAAGCGGCCGGCGTGAATCGTCCGGACGTGATGCAGAGGAAGGGCCTCTA
TCCGCCGCCGGCCGGCGCCTCCGACATTCCCGGTCTCGAGATCGCCGGCACGGTGGTCGCGACGGGCCCGGAGACGCAGC
GCTTCAAGGTGGGCGACCGCGTGTGCGCCCTCGTCACCGGGGGCGGCTATGCGGAATATTGCACCACCTCCGCCCTCACG
GCCCTGCCCATTCCGGACGGCCTGTCCGCCACTGAGGCCGCGGCCCTGCCGGAAACCTTCTTCACGGTCTGGAGCAACGT
GTTCGACCGCGGCCGCCTGCAGCCGGGCGAAGTGCTCCTCGTCCATGGCGGCACCAGCGGCATCGGCACGACGGCGATCC
AGCTCGCCAAGGCCTTTGGTTCGAAGGTCTTCGTCACCGTGGGCTCGCCGGAGAAGTGCGAGGCGGCCCGCAAGCTCGGC
GCGGATCTCGCCATCGACTACAACACCCAGGACTTCGTGGCCGAGGTGAAGAGCGCCACCGGCGGCAAGGGCGCCGACGT
CATCCTCGACATGGTGGCCGGCGATTATATCGCCCGCAATTACGAGGCCGCGGCGGTGGATGGGCGCATCGTGCAGATCG
CCTTCCAGAAGGGCTCGAAGGCCCAGGTGGACTTCATGCGCGTCATGCTGAAGCGCCTCACCCACACCGGCTCGACCCTG
CGTTCCCGCCCCGTGGCCGACAAGGCCCTCATCGCACAGGCGCTGGAAGAGAAGGTGTGGCCGCTCATCGCCAAGGGCAG
CGTGAAGCCGCTGATCGATGCCACCTTCCCGCTGAAGGAGGCGGCTGCCGCCCACGCGCACATGGAAGGCAGCACCCACA
TCGGCAAGATCGTTCTCACGATCGGGTGA

Upstream 100 bases:

>100_bases
CTCGGACAGACGGCTCACGTCCGCGCCCGGCGCGATCGGCGAAGGCGGCGGCGCGGGGCGATCGTCATCCATGTGAAATC
TCCTGTGGGCCGGCGATCCG

Downstream 100 bases:

>100_bases
ACGAACCGCCCCCGGCTGGCCGAAGTGCCGCTTGGTCATGTGGAAAGCCGCTGGCAGGGCGGGCGCGAAGCCTTATGATG
CCAGCGGCGGATGCCTTGCT

Product: zinc-binding dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MLRHFHPRPDGLPERRRPTSTGQPPRASAEGASGARHHPSPSPFRGAAMTTPLPATMTAITIPTPGGPEALVPGERPVPQ
PVKGELLVKVKAAGVNRPDVMQRKGLYPPPAGASDIPGLEIAGTVVATGPETQRFKVGDRVCALVTGGGYAEYCTTSALT
ALPIPDGLSATEAAALPETFFTVWSNVFDRGRLQPGEVLLVHGGTSGIGTTAIQLAKAFGSKVFVTVGSPEKCEAARKLG
ADLAIDYNTQDFVAEVKSATGGKGADVILDMVAGDYIARNYEAAAVDGRIVQIAFQKGSKAQVDFMRVMLKRLTHTGSTL
RSRPVADKALIAQALEEKVWPLIAKGSVKPLIDATFPLKEAAAAHAHMEGSTHIGKIVLTIG

Sequences:

>Translated_382_residues
MLRHFHPRPDGLPERRRPTSTGQPPRASAEGASGARHHPSPSPFRGAAMTTPLPATMTAITIPTPGGPEALVPGERPVPQ
PVKGELLVKVKAAGVNRPDVMQRKGLYPPPAGASDIPGLEIAGTVVATGPETQRFKVGDRVCALVTGGGYAEYCTTSALT
ALPIPDGLSATEAAALPETFFTVWSNVFDRGRLQPGEVLLVHGGTSGIGTTAIQLAKAFGSKVFVTVGSPEKCEAARKLG
ADLAIDYNTQDFVAEVKSATGGKGADVILDMVAGDYIARNYEAAAVDGRIVQIAFQKGSKAQVDFMRVMLKRLTHTGSTL
RSRPVADKALIAQALEEKVWPLIAKGSVKPLIDATFPLKEAAAAHAHMEGSTHIGKIVLTIG
>Mature_382_residues
MLRHFHPRPDGLPERRRPTSTGQPPRASAEGASGARHHPSPSPFRGAAMTTPLPATMTAITIPTPGGPEALVPGERPVPQ
PVKGELLVKVKAAGVNRPDVMQRKGLYPPPAGASDIPGLEIAGTVVATGPETQRFKVGDRVCALVTGGGYAEYCTTSALT
ALPIPDGLSATEAAALPETFFTVWSNVFDRGRLQPGEVLLVHGGTSGIGTTAIQLAKAFGSKVFVTVGSPEKCEAARKLG
ADLAIDYNTQDFVAEVKSATGGKGADVILDMVAGDYIARNYEAAAVDGRIVQIAFQKGSKAQVDFMRVMLKRLTHTGSTL
RSRPVADKALIAQALEEKVWPLIAKGSVKPLIDATFPLKEAAAAHAHMEGSTHIGKIVLTIG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=39.6969696969697, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=39.6969696969697, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=30.3030303030303, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=30.3030303030303, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=30.5732484076433, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI24308257, Length=342, Percent_Identity=27.4853801169591, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=27.7439024390244, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI41872631, Length=308, Percent_Identity=30.8441558441558, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI47519420, Length=382, Percent_Identity=28.0104712041885, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI28557745, Length=270, Percent_Identity=31.8518518518519, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI197927207, Length=192, Percent_Identity=28.125, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790485, Length=330, Percent_Identity=32.4242424242424, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787863, Length=346, Percent_Identity=28.9017341040462, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081918, Length=305, Percent_Identity=25.9016393442623, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=330, Percent_Identity=26.0606060606061, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=306, Percent_Identity=29.0849673202614, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562584, Length=307, Percent_Identity=26.3843648208469, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=359, Percent_Identity=24.5125348189415, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=311, Percent_Identity=26.3665594855305, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71987554, Length=220, Percent_Identity=30.4545454545455, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=338, Percent_Identity=28.1065088757396, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323961, Length=307, Percent_Identity=28.3387622149837, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324486, Length=283, Percent_Identity=27.9151943462898, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=331, Percent_Identity=25.9818731117825, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=310, Percent_Identity=24.8387096774194, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24581345, Length=338, Percent_Identity=28.4023668639053, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19920632, Length=300, Percent_Identity=29, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221330659, Length=300, Percent_Identity=29, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 39993; Mature: 39993

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRHFHPRPDGLPERRRPTSTGQPPRASAEGASGARHHPSPSPFRGAAMTTPLPATMTAI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
TIPTPGGPEALVPGERPVPQPVKGELLVKVKAAGVNRPDVMQRKGLYPPPAGASDIPGLE
EECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCE
IAGTVVATGPETQRFKVGDRVCALVTGGGYAEYCTTSALTALPIPDGLSATEAAALPETF
EECEEEECCCCCCEEECCCEEEEEEECCCHHHHHHHHCEEEECCCCCCCHHHHHHHHHHH
FTVWSNVFDRGRLQPGEVLLVHGGTSGIGTTAIQLAKAFGSKVFVTVGSPEKCEAARKLG
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCC
ADLAIDYNTQDFVAEVKSATGGKGADVILDMVAGDYIARNYEAAAVDGRIVQIAFQKGSK
CCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCCC
AQVDFMRVMLKRLTHTGSTLRSRPVADKALIAQALEEKVWPLIAKGSVKPLIDATFPLKE
CHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCEEECCCCCCHHCCCCCHHH
AAAAHAHMEGSTHIGKIVLTIG
HHHHHHHCCCCCCEEEEEEEEC
>Mature Secondary Structure
MLRHFHPRPDGLPERRRPTSTGQPPRASAEGASGARHHPSPSPFRGAAMTTPLPATMTAI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
TIPTPGGPEALVPGERPVPQPVKGELLVKVKAAGVNRPDVMQRKGLYPPPAGASDIPGLE
EECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCE
IAGTVVATGPETQRFKVGDRVCALVTGGGYAEYCTTSALTALPIPDGLSATEAAALPETF
EECEEEECCCCCCEEECCCEEEEEEECCCHHHHHHHHCEEEECCCCCCCHHHHHHHHHHH
FTVWSNVFDRGRLQPGEVLLVHGGTSGIGTTAIQLAKAFGSKVFVTVGSPEKCEAARKLG
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCC
ADLAIDYNTQDFVAEVKSATGGKGADVILDMVAGDYIARNYEAAAVDGRIVQIAFQKGSK
CCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCCC
AQVDFMRVMLKRLTHTGSTLRSRPVADKALIAQALEEKVWPLIAKGSVKPLIDATFPLKE
CHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCEEECCCCCCHHCCCCCHHH
AAAAHAHMEGSTHIGKIVLTIG
HHHHHHHCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]