Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 158422105

GI number: 158422105

Start: 537870

End: 538775

Strand: Reverse

Name: livH [H]

Synonym: AZC_0481

Alternate gene names: 158422105

Gene position: 538775-537870 (Counterclockwise)

Preceding gene: 158422106

Following gene: 158422104

Centisome position: 10.03

GC content: 66.23

Gene sequence:

>906_bases
ATGACCGCCGCGCGGAGAGGGGCCGCGCCGTCCATGCTGACGCAGCAGATCATCAACGGCCTGATGCTCGGTGCCATCTA
CATGCTCGTGGCAGTGGCCTTCACCCTTGCCATCGGCGTCCTGAACTTTCTCAACTTCTCGCTTCCTGGCCTGTTCATGC
TGGGCGGCATGGCGGCCTTCGGCTTCCTGAAGCTCGGCTGGCCCTTTCTGGTAGCGGCGGGCGGCGCGCTGCTGATCGCC
GCCTTCGTGTCCCTGCTGGTGGAGCGCCTCGCCTACCGCCGCATGCAAGGTGGCGATCCGGAAGTGCCGCTCGTCTCCTC
GCTCGGCTTCCTGGTGCTGCTGGAGAACCTCGTCCTCATCCGCTACGGGTCGGACCAACAGGCCTTCCCTGCCTTGTTCC
CCGATATGAACCTGCGCATCGGCGGCCTCGTCGTCGGCATCGCGCAGATGGTGTCGCTCGCCATCTCGCTGGCGCTGGTG
GCCTGGCTCTCCTGGTTCCTGCGCACCACGAATACCGGGCGCCGCATCCGCACGGTGGCGGAGAGCCGCGAGACCGCGCT
GCTCATGGGCATCAACATCCAGAGCCTCGTGCCGCAGCTCTTCGTGGCCAGCGCGCTGCTGGCTGCGCTCGGCGGACTGC
TGTTCGCGGTCAATTACCAGCAGGTGTCGCCCTTCATGGGTGAGGGCATCGGCTTCAAGGGCGTCGCCGCCATGATCATC
GGCGGCATGGGCTCCATCTGGGGCGCGGTCATCGGTGGCCTGCTGATCGGCCTCGCCGAGGTGCTTTCCATCAGTCTCAT
CGGTGCGGATGTGGTGAACATCACTGTGTACGGCTTGCTGCTCGCCATCCTGATCCTGCGACCGCAAGGTCTCTTCGGCC
GGCCGCCGGCGCGGGAGAAGCTGTGA

Upstream 100 bases:

>100_bases
GCCCGTCCCGGAGGCTGAAATCCGCCTGAAATTTCAGCTTGACCGGACGCGACAATTAGCTTTGCTTGTTACCTAAATTA
CTTGCATTCCTGCGGCGGCG

Downstream 100 bases:

>100_bases
TGAGCGGCTATCTCACCGGCGTCCTCGTCGTCCTCTCCTTCAACATCATGGCGGCCTATGCGGTGTATCTGCCGCTCGCC
GCCGGCCAGCTCAATCTCGG

Product: branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTAARRGAAPSMLTQQIINGLMLGAIYMLVAVAFTLAIGVLNFLNFSLPGLFMLGGMAAFGFLKLGWPFLVAAGGALLIA
AFVSLLVERLAYRRMQGGDPEVPLVSSLGFLVLLENLVLIRYGSDQQAFPALFPDMNLRIGGLVVGIAQMVSLAISLALV
AWLSWFLRTTNTGRRIRTVAESRETALLMGINIQSLVPQLFVASALLAALGGLLFAVNYQQVSPFMGEGIGFKGVAAMII
GGMGSIWGAVIGGLLIGLAEVLSISLIGADVVNITVYGLLLAILILRPQGLFGRPPAREKL

Sequences:

>Translated_301_residues
MTAARRGAAPSMLTQQIINGLMLGAIYMLVAVAFTLAIGVLNFLNFSLPGLFMLGGMAAFGFLKLGWPFLVAAGGALLIA
AFVSLLVERLAYRRMQGGDPEVPLVSSLGFLVLLENLVLIRYGSDQQAFPALFPDMNLRIGGLVVGIAQMVSLAISLALV
AWLSWFLRTTNTGRRIRTVAESRETALLMGINIQSLVPQLFVASALLAALGGLLFAVNYQQVSPFMGEGIGFKGVAAMII
GGMGSIWGAVIGGLLIGLAEVLSISLIGADVVNITVYGLLLAILILRPQGLFGRPPAREKL
>Mature_300_residues
TAARRGAAPSMLTQQIINGLMLGAIYMLVAVAFTLAIGVLNFLNFSLPGLFMLGGMAAFGFLKLGWPFLVAAGGALLIAA
FVSLLVERLAYRRMQGGDPEVPLVSSLGFLVLLENLVLIRYGSDQQAFPALFPDMNLRIGGLVVGIAQMVSLAISLALVA
WLSWFLRTTNTGRRIRTVAESRETALLMGINIQSLVPQLFVASALLAALGGLLFAVNYQQVSPFMGEGIGFKGVAAMIIG
GMGSIWGAVIGGLLIGLAEVLSISLIGADVVNITVYGLLLAILILRPQGLFGRPPAREKL

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=305, Percent_Identity=33.4426229508197, Blast_Score=148, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 31774; Mature: 31643

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAARRGAAPSMLTQQIINGLMLGAIYMLVAVAFTLAIGVLNFLNFSLPGLFMLGGMAAF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GFLKLGWPFLVAAGGALLIAAFVSLLVERLAYRRMQGGDPEVPLVSSLGFLVLLENLVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEE
RYGSDQQAFPALFPDMNLRIGGLVVGIAQMVSLAISLALVAWLSWFLRTTNTGRRIRTVA
EECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ESRETALLMGINIQSLVPQLFVASALLAALGGLLFAVNYQQVSPFMGEGIGFKGVAAMII
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHH
GGMGSIWGAVIGGLLIGLAEVLSISLIGADVVNITVYGLLLAILILRPQGLFGRPPAREK
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
L
C
>Mature Secondary Structure 
TAARRGAAPSMLTQQIINGLMLGAIYMLVAVAFTLAIGVLNFLNFSLPGLFMLGGMAAF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GFLKLGWPFLVAAGGALLIAAFVSLLVERLAYRRMQGGDPEVPLVSSLGFLVLLENLVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEE
RYGSDQQAFPALFPDMNLRIGGLVVGIAQMVSLAISLALVAWLSWFLRTTNTGRRIRTVA
EECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ESRETALLMGINIQSLVPQLFVASALLAALGGLLFAVNYQQVSPFMGEGIGFKGVAAMII
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHH
GGMGSIWGAVIGGLLIGLAEVLSISLIGADVVNITVYGLLLAILILRPQGLFGRPPAREK
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]