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The map label for this gene is ubiB [C]

Identifier: 158422071

GI number: 158422071

Start: 500915

End: 502270

Strand: Reverse

Name: ubiB [C]

Synonym: AZC_0447

Alternate gene names: 158422071

Gene position: 502270-500915 (Counterclockwise)

Preceding gene: 158422072

Following gene: 158422070

Centisome position: 9.35

GC content: 68.81

Gene sequence:

>1356_bases
ATGACTTCTCAAGACGATGCCGAACGCAACCGCTTCTCCGCGCGCGCCGCGCGCTATGCCCGTGTGGGCGTGAATGTGGG
GGGCGTTGCCGCGCGCATCGCCGGCGCGCGGCTGATGGGCGGGGCGGGCGCGGGCAACGCGGAAGCGCTGGCGGCGGCGC
TCGGCGGGCTCAAGGGGCCGCTCATGAAGGTGGCGCAGCTCATGGCCACCGTGCCGGACGTGCTGCCGCCGGAATATGCG
AGCGAACTCCAGAAGCTCCAGAGCGATGCCCCGCCCATGGGCTGGAGCTTCGTGCGCCGTCGCATGATGGCCGAGCTGGG
CCGCGACTGGGAAAGCCGCTTCTCCTCCTTCGAGCACAAGCCCGCCGCCGCCGCCTCGCTGGGGCAGGTGCACCGGGCGG
TGGCGCTCGATGGCGACCAGCTCGCCTGCAAGCTCCAGTATCCGGACATGCAGGCCGCCGTGGAGGCGGACCTCAACCAG
TTGGACGTCCTCTTCTCCATTCACCGCCGCATGGACCCGGCCATCGACACGCGGGAGATCGCCACCGAGATCGGCGCCCG
CATCCGCGAGGAACTGGATTACCGGCGCGAGGCCAAGCACGCGAAGCTCTATGCGCGGATGCTCGCCGGCCAGCCCCATG
TGCGCGTGCCCCATGTGCGTGACGACCTTTCCACCGGCCGCCTGCTGACGCTGCAATGGCTGGAAGGCACCAAGATCCTC
GCCTTCAAGGATCACAGCCTCGAGGAGCGCAACCTGCTGGCGCGGGCCATGTTCACCGCCTGGTGGCTGCCCTTCAGCCA
GTATGGCGTCATCCATGGCGACCCCCACCTCGGCAATTATACCGTCTTCACGGATGCGGATGGCGGGCCGCAGGGCATCA
ACCTGCTCGATTACGGCTGCATCCGCATCTTCCCGCCGCGCTTCGTGGCGGGCGTGGTGGACCTCTACCGGGGCCTTGAG
GCGCATGACGAGGCCCGCGTGGTCCATGCCTATGAGACGTGGGGCTTCAACGGCCTCACCCGCGAACTCATCGACACCCT
CAACATCTGGGCGCGCTTCATCTATGGCCCGCTGCTGGACGACCGGGTGCGCACCATCGCCGACGGCGTGGAGCCGGGCC
AGTACGGCCGGAAGGAGGCCTTCCAGGTGCACACCGCCCTGAAGCGCCTCGGCCCCGTGACGGTGCCCCGCGAATTCGTC
TTCATGGACCGGGCCGCCATCGGCCTCGGTGCCGTCTTCCTGCACCTGAGGGCCGAGCAGAATTTCCATGCGCTGTTCGA
GGAGGCCATCGTCGGTTTCTCCCACGAGGCGGTTGCGGCCCGTCAGGCGGAGGCGCTGGCGGAGGCCGGCCTGTGA

Upstream 100 bases:

>100_bases
GACGTGCTGACCCCTCTCTCCCTGCTCGTCCTCCTGGCGCTCACCGTCCGATCCGCACGCAGCTGAGCGGCGTAAAGGGG
GCGAGCAGAAAAGGCGCCCC

Downstream 100 bases:

>100_bases
ACAGGGCGGGATTCGAACCCTTGGCAACGCTCGGGAATTGACATCCGTCCGCGCGCCCCGTATCAGGCGCGCTCCGATCC
ATTCTAATGGCCCGATGAGC

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTSQDDAERNRFSARAARYARVGVNVGGVAARIAGARLMGGAGAGNAEALAAALGGLKGPLMKVAQLMATVPDVLPPEYA
SELQKLQSDAPPMGWSFVRRRMMAELGRDWESRFSSFEHKPAAAASLGQVHRAVALDGDQLACKLQYPDMQAAVEADLNQ
LDVLFSIHRRMDPAIDTREIATEIGARIREELDYRREAKHAKLYARMLAGQPHVRVPHVRDDLSTGRLLTLQWLEGTKIL
AFKDHSLEERNLLARAMFTAWWLPFSQYGVIHGDPHLGNYTVFTDADGGPQGINLLDYGCIRIFPPRFVAGVVDLYRGLE
AHDEARVVHAYETWGFNGLTRELIDTLNIWARFIYGPLLDDRVRTIADGVEPGQYGRKEAFQVHTALKRLGPVTVPREFV
FMDRAAIGLGAVFLHLRAEQNFHALFEEAIVGFSHEAVAARQAEALAEAGL

Sequences:

>Translated_451_residues
MTSQDDAERNRFSARAARYARVGVNVGGVAARIAGARLMGGAGAGNAEALAAALGGLKGPLMKVAQLMATVPDVLPPEYA
SELQKLQSDAPPMGWSFVRRRMMAELGRDWESRFSSFEHKPAAAASLGQVHRAVALDGDQLACKLQYPDMQAAVEADLNQ
LDVLFSIHRRMDPAIDTREIATEIGARIREELDYRREAKHAKLYARMLAGQPHVRVPHVRDDLSTGRLLTLQWLEGTKIL
AFKDHSLEERNLLARAMFTAWWLPFSQYGVIHGDPHLGNYTVFTDADGGPQGINLLDYGCIRIFPPRFVAGVVDLYRGLE
AHDEARVVHAYETWGFNGLTRELIDTLNIWARFIYGPLLDDRVRTIADGVEPGQYGRKEAFQVHTALKRLGPVTVPREFV
FMDRAAIGLGAVFLHLRAEQNFHALFEEAIVGFSHEAVAARQAEALAEAGL
>Mature_450_residues
TSQDDAERNRFSARAARYARVGVNVGGVAARIAGARLMGGAGAGNAEALAAALGGLKGPLMKVAQLMATVPDVLPPEYAS
ELQKLQSDAPPMGWSFVRRRMMAELGRDWESRFSSFEHKPAAAASLGQVHRAVALDGDQLACKLQYPDMQAAVEADLNQL
DVLFSIHRRMDPAIDTREIATEIGARIREELDYRREAKHAKLYARMLAGQPHVRVPHVRDDLSTGRLLTLQWLEGTKILA
FKDHSLEERNLLARAMFTAWWLPFSQYGVIHGDPHLGNYTVFTDADGGPQGINLLDYGCIRIFPPRFVAGVVDLYRGLEA
HDEARVVHAYETWGFNGLTRELIDTLNIWARFIYGPLLDDRVRTIADGVEPGQYGRKEAFQVHTALKRLGPVTVPREFVF
MDRAAIGLGAVFLHLRAEQNFHALFEEAIVGFSHEAVAARQAEALAEAGL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=287, Percent_Identity=29.2682926829268, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI27363457, Length=433, Percent_Identity=24.9422632794457, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI41393593, Length=290, Percent_Identity=30, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI34147522, Length=397, Percent_Identity=23.9294710327456, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI217416386, Length=355, Percent_Identity=25.9154929577465, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI217035081, Length=219, Percent_Identity=29.6803652968037, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI2367309, Length=264, Percent_Identity=26.5151515151515, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565180, Length=392, Percent_Identity=24.234693877551, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17559152, Length=254, Percent_Identity=30.3149606299213, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=266, Percent_Identity=27.8195488721804, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323282, Length=267, Percent_Identity=24.7191011235955, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859849, Length=396, Percent_Identity=25.2525252525253, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24662575, Length=285, Percent_Identity=29.4736842105263, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI22024280, Length=345, Percent_Identity=24.6376811594203, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 49872; Mature: 49740

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQDDAERNRFSARAARYARVGVNVGGVAARIAGARLMGGAGAGNAEALAAALGGLKGP
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHH
LMKVAQLMATVPDVLPPEYASELQKLQSDAPPMGWSFVRRRMMAELGRDWESRFSSFEHK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCC
PAAAASLGQVHRAVALDGDQLACKLQYPDMQAAVEADLNQLDVLFSIHRRMDPAIDTREI
CHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ATEIGARIREELDYRREAKHAKLYARMLAGQPHVRVPHVRDDLSTGRLLTLQWLEGTKIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEE
AFKDHSLEERNLLARAMFTAWWLPFSQYGVIHGDPHLGNYTVFTDADGGPQGINLLDYGC
EEECCCCHHHHHHHHHHHHHHHCCHHHCCCEECCCCCCCEEEEECCCCCCCCCCHHHCCH
IRIFPPRFVAGVVDLYRGLEAHDEARVVHAYETWGFNGLTRELIDTLNIWARFIYGPLLD
HEECCHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DRVRTIADGVEPGQYGRKEAFQVHTALKRLGPVTVPREFVFMDRAAIGLGAVFLHLRAEQ
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NFHALFEEAIVGFSHEAVAARQAEALAEAGL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSQDDAERNRFSARAARYARVGVNVGGVAARIAGARLMGGAGAGNAEALAAALGGLKGP
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHH
LMKVAQLMATVPDVLPPEYASELQKLQSDAPPMGWSFVRRRMMAELGRDWESRFSSFEHK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCC
PAAAASLGQVHRAVALDGDQLACKLQYPDMQAAVEADLNQLDVLFSIHRRMDPAIDTREI
CHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ATEIGARIREELDYRREAKHAKLYARMLAGQPHVRVPHVRDDLSTGRLLTLQWLEGTKIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEE
AFKDHSLEERNLLARAMFTAWWLPFSQYGVIHGDPHLGNYTVFTDADGGPQGINLLDYGC
EEECCCCHHHHHHHHHHHHHHHCCHHHCCCEECCCCCCCEEEEECCCCCCCCCCHHHCCH
IRIFPPRFVAGVVDLYRGLEAHDEARVVHAYETWGFNGLTRELIDTLNIWARFIYGPLLD
HEECCHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DRVRTIADGVEPGQYGRKEAFQVHTALKRLGPVTVPREFVFMDRAAIGLGAVFLHLRAEQ
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NFHALFEEAIVGFSHEAVAARQAEALAEAGL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA