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The map label for this gene is pntB [H]

Identifier: 158422056

GI number: 158422056

Start: 485497

End: 486894

Strand: Direct

Name: pntB [H]

Synonym: AZC_0432

Alternate gene names: 158422056

Gene position: 485497-486894 (Clockwise)

Preceding gene: 158422055

Following gene: 158422059

Centisome position: 9.04

GC content: 66.81

Gene sequence:

>1398_bases
ATGACTGCCAATCTGGCCGCCCTGCTTTATCTCATCGCGGGCATCCTGTTCATCCTGGCGCTGCGGGGCCTCTCGCATCC
CACCACGTCGCGGCAGGGCAACCTGTTCGGCATGGTCGGCATGGGCATCGCCGTGCTCACCACGCTGGCGCTCTCCCCGC
CCGCCGACGCGTTCGGCTGGGTGCTGGTGATCGCGGGCATCGCCATCGGCGCCGGTGTCGGCGCCGTTGTGGCCCGCCGC
ATCGCCATGACCGCCATGCCGCAGCTCGTCGCCGCCTTCCACTCGCTGGTGGGCCTCGCGGCAGTGCTGGTCGCGGCTGC
CGCGCTCTATGCGCCCGCCGCCTTCGGCATCGGTGACTACGGCCACATCCACGGCGCGAGCCTCGTGGAAATGGTGCTCG
GCGTCGCCATCGGCGCCATCACCTTCACCGGTTCGGTGATCGCGTTCGCCAAGCTCAACGGCAACATGTCGGGCAAGCCG
ATCATGCTGCCGGGCCGGCACTACATCAACGGCGGTCTGACGCTGCTGCTGCTGGTGCTGATCGTCGCCTTCGTGATGAC
CGGTTCGTCGGTGCTGTTCTGGCTCATCACCATCCTGTCGCTGGTGCTCGGCGGCCTGCTGATCATCCCGATCGGCGGCG
CCGACATGCCGGTGGTCGTCTCCATGCTCAACTCCTATTCGGGTTGGGCGGCGGCCGGCATCGGCTTCACGCTGGGCAAC
ACCGCGCTCATCATCACCGGCGCGCTGGTCGGCTCCTCCGGCGCCATCCTGTCCTACATCATGTGTAAGGGCATGAACCG
CTCCTTCATCTCGGTCATCCTCGGCGGCTTCGGCGGCGAGGTGGCGGGTGCGGCCGGCGGCGCGGTGGAAGCCCGCCCCG
TGAAGCAGGGCTCGGCGGACGACGCGGCCTACATCATGAAGAACGCCCAGAAGGTCATCATCGTGCCGGGCTACGGCATG
GCGGTGGCGCAGGCCCAGCACGCCTTGCGCGAGATGGCCGACAAGCTGAAGGCGGAAGGCGTCGAGGTGAAGTACGCCAT
CCACCCCGTGGCGGGCCGCATGCCGGGGCATATGAACGTGCTGCTGGCGGAAGCCCAGGTGCCGTACGACGAGGTCTTCG
AGCTCGAGGACATCAACTCGGAGTTCGCCCAGGCGGACGTGGCCTTCGTCATCGGCGCCAACGACGTGACCAACCCCGCC
GCAAAGACGGATCCGGCCTCGCCCATCTTCGGCATGCCGATCCTCGACGTGGAGAAGGCCAAGACCGTTCTCTTCATCAA
GCGCGGCATGGGCTCGGGCTATGCGGGCGTGGAGAACGAACTGTTCTTCCGAGACAACACCCTGATGCTCTTCGGCGACG
CCAAGAAGGTCACCGAGGAAGTGGTGAAGAACCTCTGA

Upstream 100 bases:

>100_bases
TTCATCGCACTGATCTTTGCATCGGTGAACATCTTCGGCGGCTTCCTCGTGACCAGCCGAATGCTCGCCATGTACCAGAA
GAAGAAGTGAGGGCGCACCG

Downstream 100 bases:

>100_bases
TCGGGTTCTTCCCGCAGGATCGAAACGAGAAGGCCCCGGAGCGATGCTCCGGGGCCTTTGTTTTGGCAAGGCGTTGCGGT
TCCGGTCGGGATCGAGCGGT

Product: NAD(P) transhydrogenase subunit beta precursor

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTANLAALLYLIAGILFILALRGLSHPTTSRQGNLFGMVGMGIAVLTTLALSPPADAFGWVLVIAGIAIGAGVGAVVARR
IAMTAMPQLVAAFHSLVGLAAVLVAAAALYAPAAFGIGDYGHIHGASLVEMVLGVAIGAITFTGSVIAFAKLNGNMSGKP
IMLPGRHYINGGLTLLLLVLIVAFVMTGSSVLFWLITILSLVLGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEVAGAAGGAVEARPVKQGSADDAAYIMKNAQKVIIVPGYGM
AVAQAQHALREMADKLKAEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AKTDPASPIFGMPILDVEKAKTVLFIKRGMGSGYAGVENELFFRDNTLMLFGDAKKVTEEVVKNL

Sequences:

>Translated_465_residues
MTANLAALLYLIAGILFILALRGLSHPTTSRQGNLFGMVGMGIAVLTTLALSPPADAFGWVLVIAGIAIGAGVGAVVARR
IAMTAMPQLVAAFHSLVGLAAVLVAAAALYAPAAFGIGDYGHIHGASLVEMVLGVAIGAITFTGSVIAFAKLNGNMSGKP
IMLPGRHYINGGLTLLLLVLIVAFVMTGSSVLFWLITILSLVLGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEVAGAAGGAVEARPVKQGSADDAAYIMKNAQKVIIVPGYGM
AVAQAQHALREMADKLKAEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AKTDPASPIFGMPILDVEKAKTVLFIKRGMGSGYAGVENELFFRDNTLMLFGDAKKVTEEVVKNL
>Mature_464_residues
TANLAALLYLIAGILFILALRGLSHPTTSRQGNLFGMVGMGIAVLTTLALSPPADAFGWVLVIAGIAIGAGVGAVVARRI
AMTAMPQLVAAFHSLVGLAAVLVAAAALYAPAAFGIGDYGHIHGASLVEMVLGVAIGAITFTGSVIAFAKLNGNMSGKPI
MLPGRHYINGGLTLLLLVLIVAFVMTGSSVLFWLITILSLVLGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGNT
ALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEVAGAAGGAVEARPVKQGSADDAAYIMKNAQKVIIVPGYGMA
VAQAQHALREMADKLKAEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAA
KTDPASPIFGMPILDVEKAKTVLFIKRGMGSGYAGVENELFFRDNTLMLFGDAKKVTEEVVKNL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=472, Percent_Identity=45.3389830508475, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI122939153, Length=472, Percent_Identity=45.3389830508475, Blast_Score=372, Evalue=1e-103,
Organism=Escherichia coli, GI1787886, Length=478, Percent_Identity=53.5564853556485, Blast_Score=474, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17550456, Length=468, Percent_Identity=45.9401709401709, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 47940; Mature: 47809

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANLAALLYLIAGILFILALRGLSHPTTSRQGNLFGMVGMGIAVLTTLALSPPADAFGW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
VLVIAGIAIGAGVGAVVARRIAMTAMPQLVAAFHSLVGLAAVLVAAAALYAPAAFGIGDY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GHIHGASLVEMVLGVAIGAITFTGSVIAFAKLNGNMSGKPIMLPGRHYINGGLTLLLLVL
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECCCHHHCCCHHHHHHHH
IVAFVMTGSSVLFWLITILSLVLGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
HHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCHHCCCEECCC
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEVAGAAGGAVEARPVKQGSAD
CEEEEEEEHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DAAYIMKNAQKVIIVPGYGMAVAQAQHALREMADKLKAEGVEVKYAIHPVAGRMPGHMNV
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEE
LLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAKTDPASPIFGMPILDVEKA
EEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHC
KTVLFIKRGMGSGYAGVENELFFRDNTLMLFGDAKKVTEEVVKNL
CEEEEEECCCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
TANLAALLYLIAGILFILALRGLSHPTTSRQGNLFGMVGMGIAVLTTLALSPPADAFGW
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
VLVIAGIAIGAGVGAVVARRIAMTAMPQLVAAFHSLVGLAAVLVAAAALYAPAAFGIGDY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GHIHGASLVEMVLGVAIGAITFTGSVIAFAKLNGNMSGKPIMLPGRHYINGGLTLLLLVL
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEECCCHHHCCCHHHHHHHH
IVAFVMTGSSVLFWLITILSLVLGGLLIIPIGGADMPVVVSMLNSYSGWAAAGIGFTLGN
HHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCHHCCCEECCC
TALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEVAGAAGGAVEARPVKQGSAD
CEEEEEEEHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DAAYIMKNAQKVIIVPGYGMAVAQAQHALREMADKLKAEGVEVKYAIHPVAGRMPGHMNV
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEE
LLAEAQVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAKTDPASPIFGMPILDVEKA
EEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHC
KTVLFIKRGMGSGYAGVENELFFRDNTLMLFGDAKKVTEEVVKNL
CEEEEEECCCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]