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The map label for this gene is 158422038

Identifier: 158422038

GI number: 158422038

Start: 467673

End: 468602

Strand: Direct

Name: 158422038

Synonym: AZC_0414

Alternate gene names: NA

Gene position: 467673-468602 (Clockwise)

Preceding gene: 158422036

Following gene: 158422040

Centisome position: 8.71

GC content: 68.17

Gene sequence:

>930_bases
ATGACCACCCTGCTCATCACCCATCCCGCGGGCCTTGCCCACGCGACCCCCACCGGCCATCCGGAACGGGCCGACCGGCT
GCGGGCGCTCGATCGCATCTTCGAGCAGGAGCGCTTCGCCAATCTGCTGCGCGATCAGGCGCCGCGCGGGGAGCGGGAGG
ACATCATCCGCGTGCATCCGGCGGACTTCGTGGACGCCTTGGGCGAGGCGACCCCGGCCGAGGGCATCGTGCGCATCGAC
AGCGACACCATCCTCTCTCCCGGCTCGTGGGAAGCGGTGCTCCGCGCCGTGGGCGGCGCGTGTTTTGCCGTGGACGAGGT
GATGGAGAAGCGCGTGGACAACGCCTTCGTCGCCATGCGCCCGCCTGGCCACCATTGCGAGACGCGTCGGCCCATGGGGT
TCTGCCTGCTCAACCAGGCCGCCATCGCCGCCCGCCATGCGCAGGCGAAATACGGCCTCGGCCGGGTGGCGATCATCGAT
TTCGACGTGCATCACGGCAACGGCACGCAGGAGATCTTCTGGGCCGACGACAGCGTGCTCTATGCCTCCACCCACGAGAT
GCCGCTCTATCCCGGCACCGGGGCGGTGGGCGAGGTGGGCATCACCGGCAACATCGTGAATGCACCGCTGCGTTCCGGCG
ATGCGGGCGACAAGTTCAAGGAGGCCTTCGAGAGCCGCATCCTGCCGCGGCTTGAGACCTTCCGGCCCGAGCTCGTCATC
ATCTCCGCCGGTTTCGACGCCCACAAGAACGATCCTCTGGCCTCCCTGCGCCTCGTGGACACGGACTTCGGCTGGGTGAC
GAAGAAGCTGATGGATGTGGCCGACAAGCATTCGGACGGCCGCCTCGTCTCCATTCTGGAGGGCGGCTACGACCTCGAAG
GCCTCGCCCAGTCCGCCGCGGCGCACGTGACGGCGTTGATGCACGGGTGA

Upstream 100 bases:

>100_bases
ACCGGAAAAGCGCGCCATACGGCGCTGGATCAAAGCGGTAGGCGTGGAATAAGGTATATCAGAAGTCGAGGAAACTGCCC
GCCAGAGAGGCCGAACGCCA

Downstream 100 bases:

>100_bases
GGCGCGCGCTGAGGTGAACGGGAGCGGTTGAGCGGGTGCTCGGCCGACGGCGACGGCTTTCGGTGAGCAGGCGCGTGTTT
GGATCACGTTGCCTGTGCGG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTTLLITHPAGLAHATPTGHPERADRLRALDRIFEQERFANLLRDQAPRGEREDIIRVHPADFVDALGEATPAEGIVRID
SDTILSPGSWEAVLRAVGGACFAVDEVMEKRVDNAFVAMRPPGHHCETRRPMGFCLLNQAAIAARHAQAKYGLGRVAIID
FDVHHGNGTQEIFWADDSVLYASTHEMPLYPGTGAVGEVGITGNIVNAPLRSGDAGDKFKEAFESRILPRLETFRPELVI
ISAGFDAHKNDPLASLRLVDTDFGWVTKKLMDVADKHSDGRLVSILEGGYDLEGLAQSAAAHVTALMHG

Sequences:

>Translated_309_residues
MTTLLITHPAGLAHATPTGHPERADRLRALDRIFEQERFANLLRDQAPRGEREDIIRVHPADFVDALGEATPAEGIVRID
SDTILSPGSWEAVLRAVGGACFAVDEVMEKRVDNAFVAMRPPGHHCETRRPMGFCLLNQAAIAARHAQAKYGLGRVAIID
FDVHHGNGTQEIFWADDSVLYASTHEMPLYPGTGAVGEVGITGNIVNAPLRSGDAGDKFKEAFESRILPRLETFRPELVI
ISAGFDAHKNDPLASLRLVDTDFGWVTKKLMDVADKHSDGRLVSILEGGYDLEGLAQSAAAHVTALMHG
>Mature_308_residues
TTLLITHPAGLAHATPTGHPERADRLRALDRIFEQERFANLLRDQAPRGEREDIIRVHPADFVDALGEATPAEGIVRIDS
DTILSPGSWEAVLRAVGGACFAVDEVMEKRVDNAFVAMRPPGHHCETRRPMGFCLLNQAAIAARHAQAKYGLGRVAIIDF
DVHHGNGTQEIFWADDSVLYASTHEMPLYPGTGAVGEVGITGNIVNAPLRSGDAGDKFKEAFESRILPRLETFRPELVII
SAGFDAHKNDPLASLRLVDTDFGWVTKKLMDVADKHSDGRLVSILEGGYDLEGLAQSAAAHVTALMHG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI153085395, Length=246, Percent_Identity=40.2439024390244, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI13128864, Length=298, Percent_Identity=35.9060402684564, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI17158039, Length=327, Percent_Identity=34.5565749235474, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI30795204, Length=327, Percent_Identity=34.5565749235474, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI30795202, Length=327, Percent_Identity=34.5565749235474, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI20070354, Length=307, Percent_Identity=35.1791530944625, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI169234807, Length=246, Percent_Identity=38.6178861788618, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI148539870, Length=246, Percent_Identity=38.6178861788618, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI62750349, Length=251, Percent_Identity=37.8486055776892, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI62750347, Length=251, Percent_Identity=37.8486055776892, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI226529806, Length=307, Percent_Identity=31.5960912052117, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI13128862, Length=305, Percent_Identity=25.2459016393443, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI13128860, Length=256, Percent_Identity=25.390625, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI8923769, Length=210, Percent_Identity=25.7142857142857, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI293336691, Length=254, Percent_Identity=24.8031496062992, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI262073088, Length=184, Percent_Identity=27.1739130434783, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540334, Length=332, Percent_Identity=34.6385542168675, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17540332, Length=312, Percent_Identity=35.2564102564103, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193206283, Length=312, Percent_Identity=35.2564102564103, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193209491, Length=246, Percent_Identity=39.8373983739837, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI25154020, Length=263, Percent_Identity=30.0380228136882, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17537347, Length=298, Percent_Identity=31.5436241610738, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25154022, Length=263, Percent_Identity=29.6577946768061, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17534739, Length=306, Percent_Identity=25.4901960784314, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561978, Length=219, Percent_Identity=28.7671232876712, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=296, Percent_Identity=25.3378378378378, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324307, Length=317, Percent_Identity=31.8611987381703, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325141, Length=327, Percent_Identity=27.82874617737, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321244, Length=256, Percent_Identity=25.78125, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=260, Percent_Identity=26.5384615384615, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=139, Percent_Identity=31.6546762589928, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281360899, Length=305, Percent_Identity=32.7868852459016, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24642146, Length=305, Percent_Identity=32.7868852459016, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24642144, Length=305, Percent_Identity=32.7868852459016, Blast_Score=157, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24642142, Length=305, Percent_Identity=32.7868852459016, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI281360801, Length=348, Percent_Identity=31.6091954022989, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281360799, Length=348, Percent_Identity=31.0344827586207, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24641720, Length=348, Percent_Identity=31.0344827586207, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24644244, Length=309, Percent_Identity=24.2718446601942, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24657891, Length=254, Percent_Identity=27.1653543307087, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33580; Mature: 33449

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLITHPAGLAHATPTGHPERADRLRALDRIFEQERFANLLRDQAPRGEREDIIRVHP
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
ADFVDALGEATPAEGIVRIDSDTILSPGSWEAVLRAVGGACFAVDEVMEKRVDNAFVAMR
HHHHHHHCCCCCCCCEEEECCCCEECCCCHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEC
PPGHHCETRRPMGFCLLNQAAIAARHAQAKYGLGRVAIIDFDVHHGNGTQEIFWADDSVL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEECCCCEE
YASTHEMPLYPGTGAVGEVGITGNIVNAPLRSGDAGDKFKEAFESRILPRLETFRPELVI
EEECCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCHHHHCCCCEEE
ISAGFDAHKNDPLASLRLVDTDFGWVTKKLMDVADKHSDGRLVSILEGGYDLEGLAQSAA
EECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
AHVTALMHG
HHHHHHCCC
>Mature Secondary Structure 
TTLLITHPAGLAHATPTGHPERADRLRALDRIFEQERFANLLRDQAPRGEREDIIRVHP
CEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
ADFVDALGEATPAEGIVRIDSDTILSPGSWEAVLRAVGGACFAVDEVMEKRVDNAFVAMR
HHHHHHHCCCCCCCCEEEECCCCEECCCCHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEC
PPGHHCETRRPMGFCLLNQAAIAARHAQAKYGLGRVAIIDFDVHHGNGTQEIFWADDSVL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEECCCCEE
YASTHEMPLYPGTGAVGEVGITGNIVNAPLRSGDAGDKFKEAFESRILPRLETFRPELVI
EEECCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCHHHHCCCCEEE
ISAGFDAHKNDPLASLRLVDTDFGWVTKKLMDVADKHSDGRLVSILEGGYDLEGLAQSAA
EECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
AHVTALMHG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]