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The map label for this gene is yfjP [H]

Identifier: 158421995

GI number: 158421995

Start: 425901

End: 426554

Strand: Reverse

Name: yfjP [H]

Synonym: AZC_0371

Alternate gene names: 158421995

Gene position: 426554-425901 (Counterclockwise)

Preceding gene: 158421997

Following gene: 158421994

Centisome position: 7.94

GC content: 73.09

Gene sequence:

>654_bases
ATGATGGGCGAGGTTCACCTGAGCGACCAAGCGACCTTCGAGGCGGCGCTCGACCGGCTTCTGTCGCTGGACGACCGCCT
GCATGCGCTGGTGGCGGAGGCCGGTCGGCCGCCGTTGCGGCGGCGGGCGCCGGACTTCGCGGGGCTGGTCAACATCATCA
TCGCCCAGCAGCTCTCCGTCGCCGCCGCCCGCGCCATCTCCGCGCGCACGGAGCAGGTGCTCGGCGGCCCGCCGACGGTC
GAGGCGCTGTTGAACGCCTCGCCGGAGACGCTGAAGGCCGGCGGCCTTTCCGCGCCGAAGATCCGCACCCTCACCCGTAT
TGCTCGCGCGCTCGCCGACGGGGTGGTGGACCTCGCCCATGTGGAGGCGATGGAAGCGGACGCGGCGGCCGACTATCTGA
CCCGCCTGCCCGGCATCGGCCGCTGGACGGCGGACATCTATCTTCTCTTCTGCCTCGGCCGCAGCGACGCCTTCCCCGAG
GGCGACCTTGCCCTCCAGGTGGCGGCCGCCGATGCCTTCGGCCTGCCGGGCCGGGCCTCGGCGCTGGGCCTTAAGGCGAT
CGCGGAGGACTGGCGGCCCTATCGCGGCGTGGCGGCCCATCTGCTCTGGGCCTATTATGGCGCCCGCCGCGCCCGTCTTG
GCGCCCCCGCCTGA

Upstream 100 bases:

>100_bases
TGGGGCTTGGGGCGAAGCGGCAGACGATGGTCATGGCAGGCCATGTCATCGCATGACCGCCGCTCCGGCGCGAGAGGGCA
AAAGGGCAAGGAGGCGCGGC

Downstream 100 bases:

>100_bases
TCCCGGATTTTCCGAATGTCCCTCACCGAAGGTCCCCGCCTCGCCCCGTCTGCGGGCGGTCCCGCCGATTCGCTCGTGGT
GCTGGTGCACGGTTATGGCG

Product: HhH-GPD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MMGEVHLSDQATFEAALDRLLSLDDRLHALVAEAGRPPLRRRAPDFAGLVNIIIAQQLSVAAARAISARTEQVLGGPPTV
EALLNASPETLKAGGLSAPKIRTLTRIARALADGVVDLAHVEAMEADAAADYLTRLPGIGRWTADIYLLFCLGRSDAFPE
GDLALQVAAADAFGLPGRASALGLKAIAEDWRPYRGVAAHLLWAYYGARRARLGAPA

Sequences:

>Translated_217_residues
MMGEVHLSDQATFEAALDRLLSLDDRLHALVAEAGRPPLRRRAPDFAGLVNIIIAQQLSVAAARAISARTEQVLGGPPTV
EALLNASPETLKAGGLSAPKIRTLTRIARALADGVVDLAHVEAMEADAAADYLTRLPGIGRWTADIYLLFCLGRSDAFPE
GDLALQVAAADAFGLPGRASALGLKAIAEDWRPYRGVAAHLLWAYYGARRARLGAPA
>Mature_217_residues
MMGEVHLSDQATFEAALDRLLSLDDRLHALVAEAGRPPLRRRAPDFAGLVNIIIAQQLSVAAARAISARTEQVLGGPPTV
EALLNASPETLKAGGLSAPKIRTLTRIARALADGVVDLAHVEAMEADAAADYLTRLPGIGRWTADIYLLFCLGRSDAFPE
GDLALQVAAADAFGLPGRASALGLKAIAEDWRPYRGVAAHLLWAYYGARRARLGAPA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 22967; Mature: 22967

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGEVHLSDQATFEAALDRLLSLDDRLHALVAEAGRPPLRRRAPDFAGLVNIIIAQQLSV
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHH
AAARAISARTEQVLGGPPTVEALLNASPETLKAGGLSAPKIRTLTRIARALADGVVDLAH
HHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEAMEADAAADYLTRLPGIGRWTADIYLLFCLGRSDAFPEGDLALQVAAADAFGLPGRAS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHCCCCCCHH
ALGLKAIAEDWRPYRGVAAHLLWAYYGARRARLGAPA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMGEVHLSDQATFEAALDRLLSLDDRLHALVAEAGRPPLRRRAPDFAGLVNIIIAQQLSV
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHH
AAARAISARTEQVLGGPPTVEALLNASPETLKAGGLSAPKIRTLTRIARALADGVVDLAH
HHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEAMEADAAADYLTRLPGIGRWTADIYLLFCLGRSDAFPEGDLALQVAAADAFGLPGRAS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHCCCCCCHH
ALGLKAIAEDWRPYRGVAAHLLWAYYGARRARLGAPA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]