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The map label for this gene is plp [H]

Identifier: 158421935

GI number: 158421935

Start: 361213

End: 362157

Strand: Direct

Name: plp [H]

Synonym: AZC_0311

Alternate gene names: 158421935

Gene position: 361213-362157 (Clockwise)

Preceding gene: 158421931

Following gene: 158421937

Centisome position: 6.73

GC content: 67.3

Gene sequence:

>945_bases
GTGGATCACATGATGCGTCCCGCTCCCACCGCCGCGCTCGCGGTTGCTCTCACCGCCTTCGCCTTCGGCGGCCAGGCGTT
CGCCCAGACGGCGGCGCCGGGCGCCACCCCGCCGGCGGCGGCAGCCCCGGCCAGGCCGGCCGACAGCGATCCGGTGGTTG
AGACGGTGAACGGCGCGCCCATCCGCGCCAGCGAACTCGCCATCGCGGAAGACGACATCGGCCCCGGCCTGCCGCAGGTG
CAGGGCGCCGCGCGTCAGGAATACATCCTGTCCTTCCTGACTGACATGACCCTGCTGGCTCAGGCCGCGCAGGCGCAGAA
GCTCGACCAGAGCCCGGAATTCGCGGCCAAGATGAACTATCTGCGCACCAAGGCGCTGATGGAGACCCTCATGGCTGCCG
AGGCCAAGAAGGCTGTGACCGAGGACGCCAAGCGCAAGACCTATGACGAGTTCGTCAAGCAGACGAAGCCGGAGACCGAG
GTCCACGCTCGCCATATCCTCGTGGACAGCGAGGCCAAGGCCAAGGAAATCGCCGCCAAGGCCAAGGCCGGCGCCGATTT
TGCCAAGCTTGCCAAGGAAAACTCCAAGGACAGCGCCGAGGATGGCGGCGATCTCGGCTACTTCACCAAGGACCAGATGG
TGCCGGAATTCGCGGACGCCGCCTTCAAGCTGGACAAGGGCCAGGTCTCCGATCCGGTGAAGACCCAGTTTGGCTGGCAC
GTCATCAAGGTCGAGGACAAGCGCCAGAAGCCGATCCCGACCTATGAGCAGGTCTCCGACCAGATCGACCAGTATCTCAT
CCGCAAGGCGCAGTCCGATCTCGTGACCAAGCTGCGCTCCGATGCGAAGGTCGAGAAGACCTCGGCCGCGCCCTCCGCCG
CCCCGGCTGCGCCCGCGACCCCTGCGGCTCCGGCCGGCGCTGCGCCTGCGGCCCCGAAGAACTGA

Upstream 100 bases:

>100_bases
CCTCCGCGGGTGTGGTGCCTCAAGAATGCCCCCTTGTCAGCGAATGTGACCTGGGCAAGGGTGCCGCCGCAACGGACGAC
CCGTTACAGCTTCAAGGACA

Downstream 100 bases:

>100_bases
CGTTTCTTGATCCGGGCGGTTCTCCGTCCGCATGGAGAAGGCCCGGCCGCTCGCGCGCGCCGGGCCTTTTCTTTGGGCCT
CAGGCGGCGCCCTTGAGGAT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase precursor

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase plp; Rotamase plp [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDHMMRPAPTAALAVALTAFAFGGQAFAQTAAPGATPPAAAAPARPADSDPVVETVNGAPIRASELAIAEDDIGPGLPQV
QGAARQEYILSFLTDMTLLAQAAQAQKLDQSPEFAAKMNYLRTKALMETLMAAEAKKAVTEDAKRKTYDEFVKQTKPETE
VHARHILVDSEAKAKEIAAKAKAGADFAKLAKENSKDSAEDGGDLGYFTKDQMVPEFADAAFKLDKGQVSDPVKTQFGWH
VIKVEDKRQKPIPTYEQVSDQIDQYLIRKAQSDLVTKLRSDAKVEKTSAAPSAAPAAPATPAAPAGAAPAAPKN

Sequences:

>Translated_314_residues
MDHMMRPAPTAALAVALTAFAFGGQAFAQTAAPGATPPAAAAPARPADSDPVVETVNGAPIRASELAIAEDDIGPGLPQV
QGAARQEYILSFLTDMTLLAQAAQAQKLDQSPEFAAKMNYLRTKALMETLMAAEAKKAVTEDAKRKTYDEFVKQTKPETE
VHARHILVDSEAKAKEIAAKAKAGADFAKLAKENSKDSAEDGGDLGYFTKDQMVPEFADAAFKLDKGQVSDPVKTQFGWH
VIKVEDKRQKPIPTYEQVSDQIDQYLIRKAQSDLVTKLRSDAKVEKTSAAPSAAPAAPATPAAPAGAAPAAPKN
>Mature_314_residues
MDHMMRPAPTAALAVALTAFAFGGQAFAQTAAPGATPPAAAAPARPADSDPVVETVNGAPIRASELAIAEDDIGPGLPQV
QGAARQEYILSFLTDMTLLAQAAQAQKLDQSPEFAAKMNYLRTKALMETLMAAEAKKAVTEDAKRKTYDEFVKQTKPETE
VHARHILVDSEAKAKEIAAKAKAGADFAKLAKENSKDSAEDGGDLGYFTKDQMVPEFADAAFKLDKGQVSDPVKTQFGWH
VIKVEDKRQKPIPTYEQVSDQIDQYLIRKAQSDLVTKLRSDAKVEKTSAAPSAAPAAPATPAAPAGAAPAAPKN

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=94, Percent_Identity=43.6170212765958, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786238, Length=102, Percent_Identity=50, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790211, Length=83, Percent_Identity=46.9879518072289, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537235, Length=96, Percent_Identity=47.9166666666667, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356303, Length=102, Percent_Identity=42.156862745098, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33255; Mature: 33255

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHMMRPAPTAALAVALTAFAFGGQAFAQTAAPGATPPAAAAPARPADSDPVVETVNGAP
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCC
IRASELAIAEDDIGPGLPQVQGAARQEYILSFLTDMTLLAQAAQAQKLDQSPEFAAKMNY
CCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LRTKALMETLMAAEAKKAVTEDAKRKTYDEFVKQTKPETEVHARHILVDSEAKAKEIAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEECCCHHHHHHHHH
AKAGADFAKLAKENSKDSAEDGGDLGYFTKDQMVPEFADAAFKLDKGQVSDPVKTQFGWH
HHCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHCCCCCCCCCCHHHCCCEE
VIKVEDKRQKPIPTYEQVSDQIDQYLIRKAQSDLVTKLRSDAKVEKTSAAPSAAPAAPAT
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
PAAPAGAAPAAPKN
CCCCCCCCCCCCCC
>Mature Secondary Structure
MDHMMRPAPTAALAVALTAFAFGGQAFAQTAAPGATPPAAAAPARPADSDPVVETVNGAP
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCC
IRASELAIAEDDIGPGLPQVQGAARQEYILSFLTDMTLLAQAAQAQKLDQSPEFAAKMNY
CCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LRTKALMETLMAAEAKKAVTEDAKRKTYDEFVKQTKPETEVHARHILVDSEAKAKEIAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEECCCHHHHHHHHH
AKAGADFAKLAKENSKDSAEDGGDLGYFTKDQMVPEFADAAFKLDKGQVSDPVKTQFGWH
HHCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHCCCCCCCCCCHHHCCCEE
VIKVEDKRQKPIPTYEQVSDQIDQYLIRKAQSDLVTKLRSDAKVEKTSAAPSAAPAAPAT
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
PAAPAGAAPAAPKN
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA