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The map label for this gene is lrp [H]

Identifier: 158421890

GI number: 158421890

Start: 310618

End: 311082

Strand: Reverse

Name: lrp [H]

Synonym: AZC_0266

Alternate gene names: 158421890

Gene position: 311082-310618 (Counterclockwise)

Preceding gene: 158421892

Following gene: 158421888

Centisome position: 5.79

GC content: 65.16

Gene sequence:

>465_bases
ATGGACGAAACGCTCGACCGGATCGACCTCAAGATCCTGCGCCTCCTGCAGGCGAACGGGCGCATGTCCAATGCGGATCT
CGCCGAGGCCGTGGCGGTGAGCCCCGCCACCTGCCACCGCCGCACCCAGCGCCTGTTCGAGCAGGGCTATCTCTCCGGCG
TGCGGGCGCAGGTGAACCCGCACAAGGTGGAGCGCGGCACACTGGTGATGGTGGGCGTGGTGCTGGACCGATCGACGCCC
GAAAGCTTCGGCGAGTTCGAGCGCGCGGTGGCGAAGCTGAAATTCGTGCTCGACTGCCATCTGGTGGCGGGCGACTTCGA
CTATTTCCTCAAGATCCGGGTGGGCGACATGGCGGACTTCAACCGCATCCACGCCCAGCAGCTCATCGCTCTGCCCAGCG
TGCGCCAGACCCGCACCTTCTTCGTGATGAAAGAAGTGGTCGACAACGCGCCGCTGGAGTTTTGA

Upstream 100 bases:

>100_bases
GCTTTCAAAGTTGACGGCGGAACTGCCGCATCTATCTTGCCAGATCGGCCATTTCGTGGAATTTCTTCAGCTCTGACGCA
ATTTTTCGGAAGATTCTTCC

Downstream 100 bases:

>100_bases
GCCGGCCCGCCCTCTTCGCCGCACAGGCCCAGAACACCGAATGAAGCGGGAGGCCCCGCTCACCCCTCGGCCAGTGACAA
CACGATGTCCCATTCCTCGT

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MDETLDRIDLKILRLLQANGRMSNADLAEAVAVSPATCHRRTQRLFEQGYLSGVRAQVNPHKVERGTLVMVGVVLDRSTP
ESFGEFERAVAKLKFVLDCHLVAGDFDYFLKIRVGDMADFNRIHAQQLIALPSVRQTRTFFVMKEVVDNAPLEF

Sequences:

>Translated_154_residues
MDETLDRIDLKILRLLQANGRMSNADLAEAVAVSPATCHRRTQRLFEQGYLSGVRAQVNPHKVERGTLVMVGVVLDRSTP
ESFGEFERAVAKLKFVLDCHLVAGDFDYFLKIRVGDMADFNRIHAQQLIALPSVRQTRTFFVMKEVVDNAPLEF
>Mature_154_residues
MDETLDRIDLKILRLLQANGRMSNADLAEAVAVSPATCHRRTQRLFEQGYLSGVRAQVNPHKVERGTLVMVGVVLDRSTP
ESFGEFERAVAKLKFVLDCHLVAGDFDYFLKIRVGDMADFNRIHAQQLIALPSVRQTRTFFVMKEVVDNAPLEF

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=142, Percent_Identity=46.4788732394366, Blast_Score=139, Evalue=6e-35,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=29.1390728476821, Blast_Score=80, Evalue=6e-17,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=24.4755244755245, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17420; Mature: 17420

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETLDRIDLKILRLLQANGRMSNADLAEAVAVSPATCHRRTQRLFEQGYLSGVRAQVNP
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
HKVERGTLVMVGVVLDRSTPESFGEFERAVAKLKFVLDCHLVAGDFDYFLKIRVGDMADF
CEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCHHH
NRIHAQQLIALPSVRQTRTFFVMKEVVDNAPLEF
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDETLDRIDLKILRLLQANGRMSNADLAEAVAVSPATCHRRTQRLFEQGYLSGVRAQVNP
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
HKVERGTLVMVGVVLDRSTPESFGEFERAVAKLKFVLDCHLVAGDFDYFLKIRVGDMADF
CEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCHHH
NRIHAQQLIALPSVRQTRTFFVMKEVVDNAPLEF
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]