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The map label for this gene is yflS [H]

Identifier: 158421879

GI number: 158421879

Start: 298002

End: 299525

Strand: Direct

Name: yflS [H]

Synonym: AZC_0255

Alternate gene names: 158421879

Gene position: 298002-299525 (Clockwise)

Preceding gene: 158421878

Following gene: 158421886

Centisome position: 5.55

GC content: 65.09

Gene sequence:

>1524_bases
ATGTGCCGGGGTTTTGAGATGATCGAACGCGTGCGTGGTCTGTTTGCCTATTTTGCCAGGGTGGTGCCCTTCCGCATCAA
GCCGGCCATCATCACCACGCTGGTGCTCTTCACCCTGCTGCTGCTGCCCGTTCCGGCCGGCCTGACGCCGAAGGCGTGGG
CGCTGGTGGCCATCTTCCTCACCACCATCGTCGCCATCATCCTCAAGGTGATGCCCATCGGCGTGATGGCCATGATGGCG
ATGACCATCGTGGCGCTCTCGCAGGTCACCGCCACCTCGTCCAAGGCCGCCATCGCTGACGCCCTTGCCAGCCTGTCCAA
TCCGCTCATCTGGCTGATCGTGGTGGCCATCTTCATTTCGCGGGGGCTCAAGAAGACGGGGCTGGGCAGCCGCATCGGCC
TCCTCTTCATCGCGCTGCTGGGGCGGCGGACCATCGGCATCGGCTATGGCCTTGCGGTCTGCGAGCTGGTGCTTGCGCCC
TTCACGCCCAGCAACACGGCGCGCGGTGGCGGCATCGTCCACCCCATCATGAAGTCCATCGCCGGCGCCTTCGGCTCCGA
CCCGGCCAAGGGCACCGAGCGCAAGATGGGCACCTATCTGGCGCTGGTGAACATGCATGCCAATCCCATCACCTCGGGCA
TGTTCATCACCGCCACCGCGCCCAATCCGCTGGTGGTGGACTATGTGGCGAAGGTCACCAACCAGAGCTTCCACCTCACC
TGGACGTCCTGGGCGCTCTACATGCTGCTGCCGGGTCTCGTCTGCCTGCTGCTGATGCCGCTCGCCATCGCCCTCCTGTC
CCCGCCGGAGGTGAAGGCGACCCCCGACGCGGTGGATTATGCTCGCGGCGAGCTGAAGCGCATGGGCGCGCTCTCCGGCG
GCGAGTGGGTGATGATCGGCACCTTCCTGCTGCTGCTGGTGCTGTGGGCGAACGTGCCCGCCATGATCTTCGGCAAGGCC
TTCGAGCTCGACCCGACCGCCGTCGCCTTCCTCGGCCTGTTCGCCCTCATCATCACCGGCACCATCGACTGGGACGACGT
GCTCTCCGAGAAGAGCGCATGGGACACGCTGATCTGGTTCGGCGCGCTGGTGATGATGGCCGAGCAGCTCAACAAGACCG
GCGTCATCGCCTGGTTCTCCAACCTGCTGAAGAGCGGCATCCTGGCGTCCGGCATGGGCTGGCAGCCGGCGGCGGCGCTG
CTGGTGCTGTGCTTCGTCTTCTCGCACTACTTCTTTGCCAGCACGACCGCCCACATCAGCGCCATGATGCTGGCCTTCCT
CACGGTGGGCCTGCAGATCGTGCCGCCGGACTTCCACATCCCCTTCCTGCTGATGATGGCGTCGGGCTCGGCCATCATGA
TGACGCTCACCCATTATGCCACCGGCACCTCGCCCATCATCTTCGGCTCGGGCTATGTGGGCCTCGGCCTGTGGTGGCGG
GTCGGCTTCGTCATGTGCGTGATCGAGCTGCTGATCTATGCGGTGGTCGGCAATCTCTGGTGGAAGGTGCTGGGCCTCTG
GTGA

Upstream 100 bases:

>100_bases
TGCATGGTTTGCGCTGTGAAAATTGACGCAGGCCTTGGCGCCCCGCCGTGAGAGATGAAAACCTGAGACTGCAACGAGCG
TTGCCGATCATCGGCGCGCG

Downstream 100 bases:

>100_bases
GAAGCGCGGCACAGCCGCCCGCCGCGGCTGCGCCGTGATCTTTCAATCGCACCGACTTCAGGCGGCGACGCCGAACAGCA
CGCCGATGCCGGCGGTCGCC

Product: sodium/sulphate symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MCRGFEMIERVRGLFAYFARVVPFRIKPAIITTLVLFTLLLLPVPAGLTPKAWALVAIFLTTIVAIILKVMPIGVMAMMA
MTIVALSQVTATSSKAAIADALASLSNPLIWLIVVAIFISRGLKKTGLGSRIGLLFIALLGRRTIGIGYGLAVCELVLAP
FTPSNTARGGGIVHPIMKSIAGAFGSDPAKGTERKMGTYLALVNMHANPITSGMFITATAPNPLVVDYVAKVTNQSFHLT
WTSWALYMLLPGLVCLLLMPLAIALLSPPEVKATPDAVDYARGELKRMGALSGGEWVMIGTFLLLLVLWANVPAMIFGKA
FELDPTAVAFLGLFALIITGTIDWDDVLSEKSAWDTLIWFGALVMMAEQLNKTGVIAWFSNLLKSGILASGMGWQPAAAL
LVLCFVFSHYFFASTTAHISAMMLAFLTVGLQIVPPDFHIPFLLMMASGSAIMMTLTHYATGTSPIIFGSGYVGLGLWWR
VGFVMCVIELLIYAVVGNLWWKVLGLW

Sequences:

>Translated_507_residues
MCRGFEMIERVRGLFAYFARVVPFRIKPAIITTLVLFTLLLLPVPAGLTPKAWALVAIFLTTIVAIILKVMPIGVMAMMA
MTIVALSQVTATSSKAAIADALASLSNPLIWLIVVAIFISRGLKKTGLGSRIGLLFIALLGRRTIGIGYGLAVCELVLAP
FTPSNTARGGGIVHPIMKSIAGAFGSDPAKGTERKMGTYLALVNMHANPITSGMFITATAPNPLVVDYVAKVTNQSFHLT
WTSWALYMLLPGLVCLLLMPLAIALLSPPEVKATPDAVDYARGELKRMGALSGGEWVMIGTFLLLLVLWANVPAMIFGKA
FELDPTAVAFLGLFALIITGTIDWDDVLSEKSAWDTLIWFGALVMMAEQLNKTGVIAWFSNLLKSGILASGMGWQPAAAL
LVLCFVFSHYFFASTTAHISAMMLAFLTVGLQIVPPDFHIPFLLMMASGSAIMMTLTHYATGTSPIIFGSGYVGLGLWWR
VGFVMCVIELLIYAVVGNLWWKVLGLW
>Mature_507_residues
MCRGFEMIERVRGLFAYFARVVPFRIKPAIITTLVLFTLLLLPVPAGLTPKAWALVAIFLTTIVAIILKVMPIGVMAMMA
MTIVALSQVTATSSKAAIADALASLSNPLIWLIVVAIFISRGLKKTGLGSRIGLLFIALLGRRTIGIGYGLAVCELVLAP
FTPSNTARGGGIVHPIMKSIAGAFGSDPAKGTERKMGTYLALVNMHANPITSGMFITATAPNPLVVDYVAKVTNQSFHLT
WTSWALYMLLPGLVCLLLMPLAIALLSPPEVKATPDAVDYARGELKRMGALSGGEWVMIGTFLLLLVLWANVPAMIFGKA
FELDPTAVAFLGLFALIITGTIDWDDVLSEKSAWDTLIWFGALVMMAEQLNKTGVIAWFSNLLKSGILASGMGWQPAAAL
LVLCFVFSHYFFASTTAHISAMMLAFLTVGLQIVPPDFHIPFLLMMASGSAIMMTLTHYATGTSPIIFGSGYVGLGLWWR
VGFVMCVIELLIYAVVGNLWWKVLGLW

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786829, Length=490, Percent_Identity=34.8979591836735, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1789444, Length=479, Percent_Identity=35.4906054279749, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1786986, Length=470, Percent_Identity=34.468085106383, Blast_Score=250, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 54654; Mature: 54654

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRGFEMIERVRGLFAYFARVVPFRIKPAIITTLVLFTLLLLPVPAGLTPKAWALVAIFL
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TTIVAIILKVMPIGVMAMMAMTIVALSQVTATSSKAAIADALASLSNPLIWLIVVAIFIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RGLKKTGLGSRIGLLFIALLGRRTIGIGYGLAVCELVLAPFTPSNTARGGGIVHPIMKSI
CCCCCCCCCHHHHHHHHHHHCCCHHCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AGAFGSDPAKGTERKMGTYLALVNMHANPITSGMFITATAPNPLVVDYVAKVTNQSFHLT
HHHCCCCCCCCHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEE
WTSWALYMLLPGLVCLLLMPLAIALLSPPEVKATPDAVDYARGELKRMGALSGGEWVMIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHH
TFLLLLVLWANVPAMIFGKAFELDPTAVAFLGLFALIITGTIDWDDVLSEKSAWDTLIWF
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHH
GALVMMAEQLNKTGVIAWFSNLLKSGILASGMGWQPAAALLVLCFVFSHYFFASTTAHIS
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMMLAFLTVGLQIVPPDFHIPFLLMMASGSAIMMTLTHYATGTSPIIFGSGYVGLGLWWR
HHHHHHHHCCCEEECCCCCHHHHHHHHCCCEEEEEHHHHCCCCCCEEECCCCHHHHHHHH
VGFVMCVIELLIYAVVGNLWWKVLGLW
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCRGFEMIERVRGLFAYFARVVPFRIKPAIITTLVLFTLLLLPVPAGLTPKAWALVAIFL
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TTIVAIILKVMPIGVMAMMAMTIVALSQVTATSSKAAIADALASLSNPLIWLIVVAIFIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RGLKKTGLGSRIGLLFIALLGRRTIGIGYGLAVCELVLAPFTPSNTARGGGIVHPIMKSI
CCCCCCCCCHHHHHHHHHHHCCCHHCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AGAFGSDPAKGTERKMGTYLALVNMHANPITSGMFITATAPNPLVVDYVAKVTNQSFHLT
HHHCCCCCCCCHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEE
WTSWALYMLLPGLVCLLLMPLAIALLSPPEVKATPDAVDYARGELKRMGALSGGEWVMIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHH
TFLLLLVLWANVPAMIFGKAFELDPTAVAFLGLFALIITGTIDWDDVLSEKSAWDTLIWF
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHH
GALVMMAEQLNKTGVIAWFSNLLKSGILASGMGWQPAAALLVLCFVFSHYFFASTTAHIS
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMMLAFLTVGLQIVPPDFHIPFLLMMASGSAIMMTLTHYATGTSPIIFGSGYVGLGLWWR
HHHHHHHHCCCEEECCCCCHHHHHHHHCCCEEEEEHHHHCCCCCCEEECCCCHHHHHHHH
VGFVMCVIELLIYAVVGNLWWKVLGLW
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]