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The map label for this gene is ackA [H]

Identifier: 158421814

GI number: 158421814

Start: 227370

End: 228551

Strand: Direct

Name: ackA [H]

Synonym: AZC_0190

Alternate gene names: 158421814

Gene position: 227370-228551 (Clockwise)

Preceding gene: 158421813

Following gene: 158421815

Centisome position: 4.23

GC content: 66.75

Gene sequence:

>1182_bases
ATGACCGATGCTGTCCTGGTGGTGAATTCCGGCTCGACAAGTCTCAAGTTCGCGGCTTATGCGGCGGGCGCCGACGCTGT
GCCGCCGCTGCTCTGCCGCGGCGTGGTGGACAGCATGACGAGCGATCCCCACTTCATCGCCAAGGCGCCGGACGGCACAC
CGATCGATGCCCATGAATGGGGGGAAGGCCAAAACCTCGGCCATGGTCGGGCGTTGTCCTTCATCATCCAATGGCTGGAG
CAGCACGAGGCCAACATCAAGGTGGTGGCGGCCGGGCACCGGGTGGTGCTGGGCGGCACCCGCTTCGAGGGGCCGGTGCG
CATCACCCCGGAGGTGCTTGACTATCTGGACGGGCTTTCCGCCATGGAGCCGTCCCACCAAGCCTATAACGTGCGGGGCG
CACGTGAACTGGCGCAGGACTTCCCCGGCCTGCCGCAGGTGGCGATGTTCGACACATCGTTCCACCGTTCCATGCCGGAG
GTGGCGCAGGTCTATGCCCTGCCCGCCGAGCTCCGCGACACCGGCGTGCGCCACTGGGGCTATCATGGCATCTCGTACGA
CTACATCAGTCGGCAGGTTCCCAAATACGTGCCGGACGCACGGCGGGTGATCGTCGCCCATCTCGGCGGCGGAGCCTCCA
TGTGCGCCATGCTGGATGGTCGCAGCATGGAGACCACCATGGCCTTCGCCGGCCTCACCGGCCTGCCCATGGCCACGCGC
TCGGGCGACGTGCCCGCCGACGTCCTCTTTTATCTTCTCAAGACGCAGGGCCATGACGTCGCAAGCCTCGAGAAGCTGCT
GTACGGCAAGTCCGGCCTCCTCGGCCTGTCCGGTGTCACCGGCGACATGCGCCAGCTTCAGGACAGCAAGGATCCTGCGG
CGGTGCTGGCGGTGGATGCCTTCGTCTATGCCATGACCAAATTCACGGGCGCCTATGCGGCGGTGCTGGGCGGCCTCGAC
GCCCTCGTCTTCACCGCGGGCATCGGCGAGAACTCGCCCATCGTGCGCGCCGCTCTCTGCGCCCGGCTGGAGTGGCTGGG
CGTGAAGCTCGACCCGGCAGCCAACACCGCGAACGGGCCGCGCATCTCGGCGACCGACAGCCGGGTGGGGGTCTTCGTCA
TCCCCACGAATGAGGAGCTGATGATCGCGCAACACACGCTGGCTCTGTTGCAGACCGCCTGA

Upstream 100 bases:

>100_bases
TCTCTATGCCGACGCTTTGGCCCGCGAGCCCGAGGCCATCCTGCCGGCAACCGCAGACTGAACGCCGCGGCCCGTCCTTC
CCCCGATGAGGAGCAAGCTC

Downstream 100 bases:

>100_bases
GCCAGGCCGCGCTGCCCGCCCGCGCGAATTGCCGCAAATCAATTCGGGTGCGGGTGACACTGTTCACGATGACGCGCCGC
GTGCGCCGCCGGAGCGGCGA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTDAVLVVNSGSTSLKFAAYAAGADAVPPLLCRGVVDSMTSDPHFIAKAPDGTPIDAHEWGEGQNLGHGRALSFIIQWLE
QHEANIKVVAAGHRVVLGGTRFEGPVRITPEVLDYLDGLSAMEPSHQAYNVRGARELAQDFPGLPQVAMFDTSFHRSMPE
VAQVYALPAELRDTGVRHWGYHGISYDYISRQVPKYVPDARRVIVAHLGGGASMCAMLDGRSMETTMAFAGLTGLPMATR
SGDVPADVLFYLLKTQGHDVASLEKLLYGKSGLLGLSGVTGDMRQLQDSKDPAAVLAVDAFVYAMTKFTGAYAAVLGGLD
ALVFTAGIGENSPIVRAALCARLEWLGVKLDPAANTANGPRISATDSRVGVFVIPTNEELMIAQHTLALLQTA

Sequences:

>Translated_393_residues
MTDAVLVVNSGSTSLKFAAYAAGADAVPPLLCRGVVDSMTSDPHFIAKAPDGTPIDAHEWGEGQNLGHGRALSFIIQWLE
QHEANIKVVAAGHRVVLGGTRFEGPVRITPEVLDYLDGLSAMEPSHQAYNVRGARELAQDFPGLPQVAMFDTSFHRSMPE
VAQVYALPAELRDTGVRHWGYHGISYDYISRQVPKYVPDARRVIVAHLGGGASMCAMLDGRSMETTMAFAGLTGLPMATR
SGDVPADVLFYLLKTQGHDVASLEKLLYGKSGLLGLSGVTGDMRQLQDSKDPAAVLAVDAFVYAMTKFTGAYAAVLGGLD
ALVFTAGIGENSPIVRAALCARLEWLGVKLDPAANTANGPRISATDSRVGVFVIPTNEELMIAQHTLALLQTA
>Mature_392_residues
TDAVLVVNSGSTSLKFAAYAAGADAVPPLLCRGVVDSMTSDPHFIAKAPDGTPIDAHEWGEGQNLGHGRALSFIIQWLEQ
HEANIKVVAAGHRVVLGGTRFEGPVRITPEVLDYLDGLSAMEPSHQAYNVRGARELAQDFPGLPQVAMFDTSFHRSMPEV
AQVYALPAELRDTGVRHWGYHGISYDYISRQVPKYVPDARRVIVAHLGGGASMCAMLDGRSMETTMAFAGLTGLPMATRS
GDVPADVLFYLLKTQGHDVASLEKLLYGKSGLLGLSGVTGDMRQLQDSKDPAAVLAVDAFVYAMTKFTGAYAAVLGGLDA
LVFTAGIGENSPIVRAALCARLEWLGVKLDPAANTANGPRISATDSRVGVFVIPTNEELMIAQHTLALLQTA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=391, Percent_Identity=37.5959079283887, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=36.8686868686869, Blast_Score=222, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 41830; Mature: 41699

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAVLVVNSGSTSLKFAAYAAGADAVPPLLCRGVVDSMTSDPHFIAKAPDGTPIDAHEW
CCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
GEGQNLGHGRALSFIIQWLEQHEANIKVVAAGHRVVLGGTRFEGPVRITPEVLDYLDGLS
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCCCEEECHHHHHHHCCHH
AMEPSHQAYNVRGARELAQDFPGLPQVAMFDTSFHRSMPEVAQVYALPAELRDTGVRHWG
HCCCCCHHCCCCHHHHHHHHCCCCCCEEEECCHHHHCCHHHHHHHHCCHHHHHCCCCCCC
YHGISYDYISRQVPKYVPDARRVIVAHLGGGASMCAMLDGRSMETTMAFAGLTGLPMATR
CCCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHEEEEECCCCHHHHHHHHCCCCCCCCCC
SGDVPADVLFYLLKTQGHDVASLEKLLYGKSGLLGLSGVTGDMRQLQDSKDPAAVLAVDA
CCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHCCCCCHHHHHHHH
FVYAMTKFTGAYAAVLGGLDALVFTAGIGENSPIVRAALCARLEWLGVKLDPAANTANGP
HHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCC
RISATDSRVGVFVIPTNEELMIAQHTLALLQTA
EEEECCCCEEEEEEECCCCEEHHHHHHHHHHCC
>Mature Secondary Structure 
TDAVLVVNSGSTSLKFAAYAAGADAVPPLLCRGVVDSMTSDPHFIAKAPDGTPIDAHEW
CCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
GEGQNLGHGRALSFIIQWLEQHEANIKVVAAGHRVVLGGTRFEGPVRITPEVLDYLDGLS
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCCCEEECHHHHHHHCCHH
AMEPSHQAYNVRGARELAQDFPGLPQVAMFDTSFHRSMPEVAQVYALPAELRDTGVRHWG
HCCCCCHHCCCCHHHHHHHHCCCCCCEEEECCHHHHCCHHHHHHHHCCHHHHHCCCCCCC
YHGISYDYISRQVPKYVPDARRVIVAHLGGGASMCAMLDGRSMETTMAFAGLTGLPMATR
CCCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHEEEEECCCCHHHHHHHHCCCCCCCCCC
SGDVPADVLFYLLKTQGHDVASLEKLLYGKSGLLGLSGVTGDMRQLQDSKDPAAVLAVDA
CCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHCCCCCHHHHHHHH
FVYAMTKFTGAYAAVLGGLDALVFTAGIGENSPIVRAALCARLEWLGVKLDPAANTANGP
HHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCC
RISATDSRVGVFVIPTNEELMIAQHTLALLQTA
EEEECCCCEEEEEEECCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA