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The map label for this gene is yfmD [H]

Identifier: 158421808

GI number: 158421808

Start: 218506

End: 219558

Strand: Direct

Name: yfmD [H]

Synonym: AZC_0184

Alternate gene names: 158421808

Gene position: 218506-219558 (Clockwise)

Preceding gene: 158421807

Following gene: 158421809

Centisome position: 4.07

GC content: 73.31

Gene sequence:

>1053_bases
GTGACGCTGGTGCTTTCCGCGCCCCGGCTGGCGCAACCACTGCGGCTCGCCGGTCTGGTGGGCGTCGTCGCCTTGCTGTT
TGTGGTGTCGCTGTTGCATCTCGGCTTCGGCGCGCGGCCCATTGCGCCGCGTGTGGTGCTTGAAGCGTTCCTAGCATTCG
ACCCGGCAAGCTTCGACCACAGGGTGGTGCGGGATCTGCGCCTGCCGCGCCTGTGCGCCGGCCTCATGGTGGGGGCGGCC
CTCGGCGTGTGCGGCGCGCTGTTGCAGGCCGTGACCCGCAATCCTTTGGGCGAACCGCACGTGCTCGGGCTCAATGCCGG
GGCGACGTTCGCCGTCGTCACCACCCTCACGCTTGGCCCCTGGTTGGGGCGCGCCGGCGTGCCCGTGCCGGCGCCGGCGA
CGCTGCTCGCCGCCCGTCCGCTGGTGGCGGCGCTGGGGGCGGGGGTCATGTTCGCCGCGGTCATGACGATCGGCGCGGCT
GGGCGCCTCGGTGCGACGCCGCTCAAGATGACCCTGTGCGGGGTGGCCCTGTCCGGCTTTGCGGCAGCGCTCACCTCGGC
CCAGCTGATCCTCGACGATCAGACGCTGGCGACGCTCCGGCTCTGGCTGGCGGGCGATCTCTCCGGCGTGTCGCGCACCG
CAGTTTGGGGCGTGCTGCCCTGGTTCGCGGCCGGTCTCGGCCTCGCCTTCGCTTTGTCCGGACGGCTGAACGTGCTTGGG
CTCGGCGACGACGTGGCGCGTGGGCTCGGGGTGAACCTCACCCGCACGCGCGGGGCGGCGCTGGTGGCGGCCGGCGTGCT
CTGCGGGGCGGCGGTCTCGCTGGCCGGTCCCGTGGGCTTCGTCGGTCTCCTTGTCCCGCACGTGGCGCGCACCCTGTTCT
CGCGCGATCACCGCCTGCTGCTGCCGCTGTGCGCGATGCTTGGGGCGAGCCTGCTTCTGGCCGCCGACCTGGCTGCGCGG
GCGCTGGCGGCGCCGCGCGAATTCGCCACCGGCGTCGTCACCGCGCTGATCGGCGTGCCGGTGTTTCTCCTGCTTGCGGC
GCGGAGCCGGTGA

Upstream 100 bases:

>100_bases
CCGTGCGCGAGGTCTATGGTCTTGCCGTCACGCGTGTCTCGCACCCGATCACCGGCGCGCCGGTGTTTCTGCCGCTGCCC
TCTACGGTGGGAGGCGCCCC

Downstream 100 bases:

>100_bases
TGGTCGGGCTCGCCGGCTATCGGCACGTCCGGCTCGGGCCGCTGGCGGTGCGGGTGCGGCCGCGCGCGGTGAGCGTCGGC
CTCGGGCTTCTGCTGCTCCT

Product: iron compound permease of ABC transporter

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTLVLSAPRLAQPLRLAGLVGVVALLFVVSLLHLGFGARPIAPRVVLEAFLAFDPASFDHRVVRDLRLPRLCAGLMVGAA
LGVCGALLQAVTRNPLGEPHVLGLNAGATFAVVTTLTLGPWLGRAGVPVPAPATLLAARPLVAALGAGVMFAAVMTIGAA
GRLGATPLKMTLCGVALSGFAAALTSAQLILDDQTLATLRLWLAGDLSGVSRTAVWGVLPWFAAGLGLAFALSGRLNVLG
LGDDVARGLGVNLTRTRGAALVAAGVLCGAAVSLAGPVGFVGLLVPHVARTLFSRDHRLLLPLCAMLGASLLLAADLAAR
ALAAPREFATGVVTALIGVPVFLLLAARSR

Sequences:

>Translated_350_residues
MTLVLSAPRLAQPLRLAGLVGVVALLFVVSLLHLGFGARPIAPRVVLEAFLAFDPASFDHRVVRDLRLPRLCAGLMVGAA
LGVCGALLQAVTRNPLGEPHVLGLNAGATFAVVTTLTLGPWLGRAGVPVPAPATLLAARPLVAALGAGVMFAAVMTIGAA
GRLGATPLKMTLCGVALSGFAAALTSAQLILDDQTLATLRLWLAGDLSGVSRTAVWGVLPWFAAGLGLAFALSGRLNVLG
LGDDVARGLGVNLTRTRGAALVAAGVLCGAAVSLAGPVGFVGLLVPHVARTLFSRDHRLLLPLCAMLGASLLLAADLAAR
ALAAPREFATGVVTALIGVPVFLLLAARSR
>Mature_349_residues
TLVLSAPRLAQPLRLAGLVGVVALLFVVSLLHLGFGARPIAPRVVLEAFLAFDPASFDHRVVRDLRLPRLCAGLMVGAAL
GVCGALLQAVTRNPLGEPHVLGLNAGATFAVVTTLTLGPWLGRAGVPVPAPATLLAARPLVAALGAGVMFAAVMTIGAAG
RLGATPLKMTLCGVALSGFAAALTSAQLILDDQTLATLRLWLAGDLSGVSRTAVWGVLPWFAAGLGLAFALSGRLNVLGL
GDDVARGLGVNLTRTRGAALVAAGVLCGAAVSLAGPVGFVGLLVPHVARTLFSRDHRLLLPLCAMLGASLLLAADLAARA
LAAPREFATGVVTALIGVPVFLLLAARSR

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=339, Percent_Identity=38.0530973451327, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790740, Length=323, Percent_Identity=37.1517027863777, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786805, Length=315, Percent_Identity=40.9523809523809, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=37.6760563380282, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=35.4166666666667, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786804, Length=316, Percent_Identity=35.7594936708861, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35445; Mature: 35314

Theoretical pI: Translated: 12.00; Mature: 12.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVLSAPRLAQPLRLAGLVGVVALLFVVSLLHLGFGARPIAPRVVLEAFLAFDPASFDH
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHH
RVVRDLRLPRLCAGLMVGAALGVCGALLQAVTRNPLGEPHVLGLNAGATFAVVTTLTLGP
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHH
WLGRAGVPVPAPATLLAARPLVAALGAGVMFAAVMTIGAAGRLGATPLKMTLCGVALSGF
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AAALTSAQLILDDQTLATLRLWLAGDLSGVSRTAVWGVLPWFAAGLGLAFALSGRLNVLG
HHHHHHHHHEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LGDDVARGLGVNLTRTRGAALVAAGVLCGAAVSLAGPVGFVGLLVPHVARTLFSRDHRLL
CCHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPLCAMLGASLLLAADLAARALAAPREFATGVVTALIGVPVFLLLAARSR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLVLSAPRLAQPLRLAGLVGVVALLFVVSLLHLGFGARPIAPRVVLEAFLAFDPASFDH
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHH
RVVRDLRLPRLCAGLMVGAALGVCGALLQAVTRNPLGEPHVLGLNAGATFAVVTTLTLGP
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHH
WLGRAGVPVPAPATLLAARPLVAALGAGVMFAAVMTIGAAGRLGATPLKMTLCGVALSGF
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AAALTSAQLILDDQTLATLRLWLAGDLSGVSRTAVWGVLPWFAAGLGLAFALSGRLNVLG
HHHHHHHHHEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LGDDVARGLGVNLTRTRGAALVAAGVLCGAAVSLAGPVGFVGLLVPHVARTLFSRDHRLL
CCHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPLCAMLGASLLLAADLAARALAAPREFATGVVTALIGVPVFLLLAARSR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]