Click here to switch to the map view.

The map label for this gene is exuT [H]

Identifier: 158421731

GI number: 158421731

Start: 127075

End: 128340

Strand: Reverse

Name: exuT [H]

Synonym: AZC_0107

Alternate gene names: 158421731

Gene position: 128340-127075 (Counterclockwise)

Preceding gene: 158421737

Following gene: 158421730

Centisome position: 2.39

GC content: 68.17

Gene sequence:

>1266_bases
ATGGCGCCGACAAGATACCGCTGGTTCGTGATCTTCCTGCTCTTCGCCATCACGGTGGTGAACTATATCGACCGCGCCGC
CATCGCTTATGCCATCACTGCCATGGAGCGCGATCTCGGCCTCTCGCCTGCCGCCGCGGGCAGCATCCTCGGCGCGTTCG
GCGTCGGCTATGCGATCACCACCCTGCTCGGCGGCTTCGCGGTGGATCGCTACGGCGCCCGCCTCGTGCTCACCATCTCC
GCCGTGCTGTGGAGCCTGTCCATCGGCGGCACCGCCATGGCCACCGGCTTTGCCAGCCTCTATGCGGCCCGCGTGCTGCT
CGGCGTGTCCGAGGGGCCGAACTTCCCGGCGCTGACCGGGGCGGTGAGCCGCTGGCTCGCGCCCAACGAGCGGGCCACCG
CGCTCGGCAACGCTCTGGTGGCGGTGCCAGTGGCCCTCGCCATCGGCGGGCCCATCGTCACGCAGCTTCTGGCCCATCTG
GACTGGCGCACGGCCTTCGGCGTCCTGTTCGCGCTCTCCATCATGTGGGTGCCGCTCTGGCTGGTCTTCTTCCGCAACCG
GCCGGAAGACTCCCGCTTCGTGAACGCTGCGGAACTCGCCCACATCCGCACGCCCGATGCGACTGGGCCCGCCAAGCCTG
CGGCGGGACACGGCCCCGGCCTCGCGCGGCTGCTGCTGACCAATCCCACGCTGGTGTCCAATTACTGGGCCTTCTTCGTC
TTCGGCTATTTCCTGTTCTTCTTCATGACCTGGCTGCCCAGCTATCTGGAGCAGGCCTATCATCTCAACCTGAAGCAGGT
CGGCCTGTTCACCGTGCTGCCCTGGCTGGCAGCGGCGGTCGCCCTGTGGTCCATGGGCCGCTGGTCGGACCATCTGCTGC
GCACCACGGGTCGCCTGCGGGTGGCGCGCTCCTATCTCATCGCCGGCTCGCAACTGGTGGCGGCGCTCGCCATCGTGCCG
GTCGCACTCACGGACAATCTCGCGGTGGCTATCACCGGCATCACGGTGGCGGTGGCCGCCTCCATGGGATCTAACGCCGC
TTATTATGCGGTGAATGTGGATGTGGTCCCTGAACGGGCGGCCTCGGCGCTCGGCATCATGGACTTCGCCTTCGCGCTTG
CCGGCTTCCTCGCCCCCGCCATCACCGGCTGGGTGCTGGCGCTGCGGGGCTCCTTCACCGACGGCTTCGCGCTCATGGCG
GCGCTGGCTCTATCCTCGGTCGTGGTCGTGCTGCTCTTCCACCATCCCGACCGCCACCGGGCCTGA

Upstream 100 bases:

>100_bases
CATGCCGTCCGCCGCTGGTCCATGGCTGGCGCCCGCAACGTGCGACTGTTGCGCGCACGCCAGCTGTCCTATGGTGGCGC
CGTGCGTAGGGGAGCGTTCG

Downstream 100 bases:

>100_bases
GGCATCAGGCCGGACGGCCATGCGGAGGGGTGAGTTGAATCGCGGGGGCGAATCGCTATGACTGGTCCCTCGCATTCGAT
GGTCAAGGCAAAGCGCAGGC

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAPTRYRWFVIFLLFAITVVNYIDRAAIAYAITAMERDLGLSPAAAGSILGAFGVGYAITTLLGGFAVDRYGARLVLTIS
AVLWSLSIGGTAMATGFASLYAARVLLGVSEGPNFPALTGAVSRWLAPNERATALGNALVAVPVALAIGGPIVTQLLAHL
DWRTAFGVLFALSIMWVPLWLVFFRNRPEDSRFVNAAELAHIRTPDATGPAKPAAGHGPGLARLLLTNPTLVSNYWAFFV
FGYFLFFFMTWLPSYLEQAYHLNLKQVGLFTVLPWLAAAVALWSMGRWSDHLLRTTGRLRVARSYLIAGSQLVAALAIVP
VALTDNLAVAITGITVAVAASMGSNAAYYAVNVDVVPERAASALGIMDFAFALAGFLAPAITGWVLALRGSFTDGFALMA
ALALSSVVVVLLFHHPDRHRA

Sequences:

>Translated_421_residues
MAPTRYRWFVIFLLFAITVVNYIDRAAIAYAITAMERDLGLSPAAAGSILGAFGVGYAITTLLGGFAVDRYGARLVLTIS
AVLWSLSIGGTAMATGFASLYAARVLLGVSEGPNFPALTGAVSRWLAPNERATALGNALVAVPVALAIGGPIVTQLLAHL
DWRTAFGVLFALSIMWVPLWLVFFRNRPEDSRFVNAAELAHIRTPDATGPAKPAAGHGPGLARLLLTNPTLVSNYWAFFV
FGYFLFFFMTWLPSYLEQAYHLNLKQVGLFTVLPWLAAAVALWSMGRWSDHLLRTTGRLRVARSYLIAGSQLVAALAIVP
VALTDNLAVAITGITVAVAASMGSNAAYYAVNVDVVPERAASALGIMDFAFALAGFLAPAITGWVLALRGSFTDGFALMA
ALALSSVVVVLLFHHPDRHRA
>Mature_420_residues
APTRYRWFVIFLLFAITVVNYIDRAAIAYAITAMERDLGLSPAAAGSILGAFGVGYAITTLLGGFAVDRYGARLVLTISA
VLWSLSIGGTAMATGFASLYAARVLLGVSEGPNFPALTGAVSRWLAPNERATALGNALVAVPVALAIGGPIVTQLLAHLD
WRTAFGVLFALSIMWVPLWLVFFRNRPEDSRFVNAAELAHIRTPDATGPAKPAAGHGPGLARLLLTNPTLVSNYWAFFVF
GYFLFFFMTWLPSYLEQAYHLNLKQVGLFTVLPWLAAAVALWSMGRWSDHLLRTTGRLRVARSYLIAGSQLVAALAIVPV
ALTDNLAVAITGITVAVAASMGSNAAYYAVNVDVVPERAASALGIMDFAFALAGFLAPAITGWVLALRGSFTDGFALMAA
LALSSVVVVLLFHHPDRHRA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=406, Percent_Identity=24.8768472906404, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI9945322, Length=353, Percent_Identity=24.3626062322946, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI6912666, Length=402, Percent_Identity=22.636815920398, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI21322234, Length=385, Percent_Identity=21.038961038961, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI9966811, Length=385, Percent_Identity=21.8181818181818, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI148743791, Length=388, Percent_Identity=23.4536082474227, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4885441, Length=394, Percent_Identity=23.6040609137056, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367379, Length=391, Percent_Identity=28.1329923273657, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87082320, Length=409, Percent_Identity=28.1173594132029, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789515, Length=420, Percent_Identity=27.8571428571429, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789152, Length=423, Percent_Identity=26.9503546099291, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI2367193, Length=413, Percent_Identity=26.634382566586, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082071, Length=431, Percent_Identity=25.9860788863109, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=421, Percent_Identity=23.9904988123515, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17554148, Length=372, Percent_Identity=21.7741935483871, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193205400, Length=338, Percent_Identity=23.6686390532544, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533556, Length=352, Percent_Identity=21.875, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=358, Percent_Identity=21.7877094972067, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554962, Length=345, Percent_Identity=21.1594202898551, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532009, Length=391, Percent_Identity=21.4833759590793, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=239, Percent_Identity=22.5941422594142, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193208223, Length=361, Percent_Identity=22.1606648199446, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=253, Percent_Identity=25.6916996047431, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561502, Length=352, Percent_Identity=23.8636363636364, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32567120, Length=352, Percent_Identity=23.8636363636364, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573708, Length=372, Percent_Identity=23.6559139784946, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI28573707, Length=372, Percent_Identity=23.6559139784946, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24639764, Length=425, Percent_Identity=25.1764705882353, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648416, Length=415, Percent_Identity=23.3734939759036, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356189, Length=415, Percent_Identity=23.3734939759036, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658658, Length=412, Percent_Identity=25.9708737864078, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19920686, Length=415, Percent_Identity=23.3734939759036, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24584153, Length=363, Percent_Identity=23.9669421487603, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24580790, Length=389, Percent_Identity=21.8508997429306, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45550495, Length=421, Percent_Identity=24.2280285035629, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573299, Length=395, Percent_Identity=23.0379746835443, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45552797, Length=421, Percent_Identity=26.1282660332542, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24658689, Length=442, Percent_Identity=26.0180995475113, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129235, Length=374, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24658666, Length=420, Percent_Identity=25, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24654215, Length=424, Percent_Identity=23.3490566037736, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922400, Length=424, Percent_Identity=23.3490566037736, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20130167, Length=397, Percent_Identity=22.1662468513854, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550460, Length=414, Percent_Identity=23.1884057971014, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641682, Length=426, Percent_Identity=23.0046948356808, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653727, Length=373, Percent_Identity=22.7882037533512, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24658674, Length=417, Percent_Identity=22.7817745803357, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655255, Length=363, Percent_Identity=23.4159779614325, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583789, Length=379, Percent_Identity=23.2189973614776, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45550364, Length=442, Percent_Identity=23.3031674208145, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI62484226, Length=370, Percent_Identity=23.7837837837838, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24655271, Length=410, Percent_Identity=21.219512195122, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130135, Length=411, Percent_Identity=21.4111922141119, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24658696, Length=338, Percent_Identity=22.7810650887574, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44928; Mature: 44797

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTRYRWFVIFLLFAITVVNYIDRAAIAYAITAMERDLGLSPAAAGSILGAFGVGYAIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TLLGGFAVDRYGARLVLTISAVLWSLSIGGTAMATGFASLYAARVLLGVSEGPNFPALTG
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AVSRWLAPNERATALGNALVAVPVALAIGGPIVTQLLAHLDWRTAFGVLFALSIMWVPLW
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFFRNRPEDSRFVNAAELAHIRTPDATGPAKPAAGHGPGLARLLLTNPTLVSNYWAFFV
HHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEHEECCCHHHHHHHHHHH
FGYFLFFFMTWLPSYLEQAYHLNLKQVGLFTVLPWLAAAVALWSMGRWSDHLLRTTGRLR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VARSYLIAGSQLVAALAIVPVALTDNLAVAITGITVAVAASMGSNAAYYAVNVDVVPERA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEEEECCHHH
ASALGIMDFAFALAGFLAPAITGWVLALRGSFTDGFALMAALALSSVVVVLLFHHPDRHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
A
C
>Mature Secondary Structure 
APTRYRWFVIFLLFAITVVNYIDRAAIAYAITAMERDLGLSPAAAGSILGAFGVGYAIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TLLGGFAVDRYGARLVLTISAVLWSLSIGGTAMATGFASLYAARVLLGVSEGPNFPALTG
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AVSRWLAPNERATALGNALVAVPVALAIGGPIVTQLLAHLDWRTAFGVLFALSIMWVPLW
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFFRNRPEDSRFVNAAELAHIRTPDATGPAKPAAGHGPGLARLLLTNPTLVSNYWAFFV
HHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEHEECCCHHHHHHHHHHH
FGYFLFFFMTWLPSYLEQAYHLNLKQVGLFTVLPWLAAAVALWSMGRWSDHLLRTTGRLR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VARSYLIAGSQLVAALAIVPVALTDNLAVAITGITVAVAASMGSNAAYYAVNVDVVPERA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEEEECCHHH
ASALGIMDFAFALAGFLAPAITGWVLALRGSFTDGFALMAALALSSVVVVLLFHHPDRHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]