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The map label for this gene is putA [H]

Identifier: 158421655

GI number: 158421655

Start: 32599

End: 35883

Strand: Reverse

Name: putA [H]

Synonym: AZC_0031

Alternate gene names: 158421655

Gene position: 35883-32599 (Counterclockwise)

Preceding gene: 158421659

Following gene: 158421651

Centisome position: 0.67

GC content: 69.28

Gene sequence:

>3285_bases
TTGAAGGATCTGGAGGATTTTTTTGTCAGTGCGGTCCAGCGCGCTCATGTTTCACGGTCACGTCACGGTCTCTCCGTGAA
AGATAAGGCAGAATGGCGAAAAGAGCCATCGAAGCGCGGCCGTTCGTGGATTACGCAAACATATCCGCCGGAGAGTGCCA
TGCCTGCCCCCACATCCCCCGTTTCCGCCTCCCTCCCGCCGTCGCCCATGCCGCCCTTCGAGGCGCCGTTCGCGCCCGAC
GACGTGGCCCTTGCCCGGCCGCTGCTCGCGCAGGGCACGCTGGCGCCGGAAGCCGAGGCCCGTATCGACGCCCTCGCCGC
CCGGCTCATCACCGCCATCCGCAAGGGCAGCAATGCGGGTGGCGTCGGCGGCATCGAGGAGGTGCTGCGCGAATACGCCC
TGTCCACCAAGGAGGGGCTGGCGCTGATGACGCTGGCGGAAGCGCTGCTGCGGGTCCCCGATTCCGCCACCGCCGACCGG
CTGATCGAGGACAAGCTGGCGCAGGGCGACTTCCTGAACCACGATTCGCGATCGAGCGCCCTGCTGGTGAATGCCTCGTC
CTGGGCGCTCGGCGTCACCGCCCGCGTCATCCAGCCGGGCGAGACGCCGGAAGGCGTGCTGGGCAAGCTCGCCAAGCGCA
TCGGCCTTCCGGCGGTGCGCACCGCCACGCGGCAGGCCATGAAGGTGCTGGGCAATCACTTCGTGCTCGGCCAGACCATC
CATGCGGCCCTCGACCGGGCGGAATCCGCGAGCGGACGGGCCTATCGCTATTCCTTCGACATGCTGGGCGAGGGCGCGCG
TACCTTCACCGATGCCAAGCGCTATTTCGACAGCTACGCCACCGCCATCGACGACATCGGCCGCCGCGCCGGCAACATGA
AGCTGCCCGACCGGCCCGGCATCTCGGTGAAGCTCTCCGCCCTCCACCCGCGCTATGACGCGGTGAACCGGGAGCGCGTC
CTCATCGAACTGGTGCCGCAGGTCATCGAGCTCGCCCGCAAGGCGAAGGCCTATGACCTCAATTTCACCATTGATGCGGA
GGAGGCCGACCGGCTCGAACTCTCCCTCGACGTGATCGACGCGGTTCTCGCCGATCCCGGCCTTGCGGGCTGGGACGGCT
TCGGCCTGGCCATCCAGGCCTATCAGAAGCGCGCGGCGGCGGTGATCGACCATATGGCGGCGCTGGCCGAGCGGCTGGAC
CGCCGGCTGATGCTGCGCCTCGTGAAGGGTGCCTATTGGGATACGGAAGTTAAGCGCGCGCAGGAGCGCGGGCTCGACGA
CTACCCCGTCTTCACCCGCAAGGCGATGACGGACCTCAATTACATGGCCTGCGCCCGCAAGCTCCTGGCGCTGCGGCCGC
GCATCTTCCCGCAGTTCGCCACCCACAATGCGCTGACCATCGCCACCATCACCGAACTCTCCGGCGGCACCGGCGGCTTC
GAGTTCCAGCGCCTGCACGGCATGGGCGATGCAGCCCATGGGGAGCGGCTCGCTGCCCATCCGGATGTGGGCTGCCGCAC
CTATGCCCCCGTGGGCGGGCATCGCGACCTGCTCGCCTATCTGGTGCGCCGCCTGCTGGAGAACGGCGCCAATTCCTCCT
TCGTCTCCGTGGCCGGCGATCCGGACGTGCCGGTGAGCGATCTCCTGCGCCGCCCGGCCACCCTCATCGGCAATGCGGAG
GAAGCCCGCAACCGCCACATCCCGTTGCCGCCGGATCTGTTCGGCCCCGGCCGCCGCAACTCGCACGGGGTGGAACTGGG
CTGCCGGTCGGTGCTGGCCGCGACGCTGACGGACATCGCGGGCCACCGCCGCGAGGTCACGGCATCAACGCTCATTGATG
GTGTGGCCCATGCGGGCGCGACCCGTACGGTGGTCAGCCCCATCGACGGAAGCGCCATCGGCCGCGTGGTGGAGGCGGAT
GCGGCCACGGCGGATGCGGCAGTCGCCGCCGCGCTGAAGGGCTTTGTGGCCTGGGACCGCACGCCGGCAAGCGAGCGCTC
CGCCCGGCTGCGCCGCGCGGCAGACCTTTTGGAGGCCCGGCAGGCAGCCTTCCTCGCGCTCCTTCAGGACGAGGCGGGCA
AGACGCTGGATGACGGCATCTCCGAGGTGCGGGAAGCCGTAGACTTCCTGCGCTATTACGCGGGCGAGGCCGAGCGTCTG
TGTGGCGCGGGCGAGACGCTGCCCGGCCCCACCGGCGAGAGCAACGTGCTGCGCCTGCGCGGGCGCGGCGTCTTTGTCGC
CATCTCGCCCTGGAACTTCCCGCTGGCCATCTTCCTCGGGCAGGTGTCCGCCGCGCTTGCCGCCGGCAATGCCGTGGTGG
CCAAGCCCGCCGAACAGACGCCCCTCATCGCCTTCGAAGCGGTGCGGCTGCTGCATGAGGCCGGCGTCCCCGCCTCTGCC
CTGCATCTCGTCACCGGCGACGGCCTCATCGGTGCGCGGCTCGTGGAGGCGCCCAAGGTGGCGGGCGTGGTCTTCACCGG
CTCCACCGAGGTGGCCCGCATCATCAACCGCACGCTTGCCGGCAAGGACGGCCCCATCGTGCCGCTGATCGCGGAGACGG
GTGGCATCAACGCCATGATCGTGGATGCCACGGCCCTGCCGGAACAGGTGTCCGATGACGTGGTGACCTCCGCCTTCCGC
TCCGCCGGCCAGCGCTGCTCGGCCCTGCGCATCCTGTTCGTGCAGGAGGACGTGGCGGACAAGATGATCGAGATGATCGT
CGGCGCCGCCGATGCGCTGAAGGTGGGCGATCCGCGCGACGCCTCGGTGCATGTGGGGCCGGTGATCGATGCCGAGGCCA
AGGCCAAGCTGGAGGCGCACATCCGGGCACTGACTGGCACCGCTCGTGTCCATTATGCCGGCACCGCGCCGACGCGCGGC
ACCTATGTGGCCCCGCACGTCTTCGAGCTGAAGCAGGCGGCGGACCTGAAGGACGAGGTCTTCGGCCCCGTCCTCCACGT
GGTGCGCTTCAAGGCGGGCGGCATCGACGGCGTGCTCGATGCCATCGCCGCCACCGGCTACGGCCTCACGCTCGGCCTCC
ACACCCGCATCGACAGCCTGGTGGAGAAGGTCACGGAGCGCCTGCCGGTGGGCAATGTCTATGTGAACCGCAACATCATC
GGTGCGGTGGTGGGGGTGCAGCCCTTCGGCGGCCACGGCCTTTCCGGCACCGGCCCGAAGGCCGGCGGACCGCACTATCT
GCTGCGCTTCGCCAGCGAGCAGACCGTGACCATCAACACGTCCGCCGCCGGCGGCAATGCGGCGCTGATGACGCAAGGCG
AGTAA

Upstream 100 bases:

>100_bases
CGAAGCCGTCCCGCTGGAGCCGCTTCAGCCGCTCGCCGGCGCTGGTGGGCGAAAGCCCCACCTGCTCCGCCAGCTCGACG
CCGGAAATGCGCCCATCCTT

Downstream 100 bases:

>100_bases
GCCCGAACTGACGGAGTATCGCGGCCGGAGCATTCCGGCCGCCGCTTTGCGGCTCGTGTCCCGAAACGGGACGCGGTCCC
GGCCGACGGTGAACGGGCGG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1094; Mature: 1094

Protein sequence:

>1094_residues
MKDLEDFFVSAVQRAHVSRSRHGLSVKDKAEWRKEPSKRGRSWITQTYPPESAMPAPTSPVSASLPPSPMPPFEAPFAPD
DVALARPLLAQGTLAPEAEARIDALAARLITAIRKGSNAGGVGGIEEVLREYALSTKEGLALMTLAEALLRVPDSATADR
LIEDKLAQGDFLNHDSRSSALLVNASSWALGVTARVIQPGETPEGVLGKLAKRIGLPAVRTATRQAMKVLGNHFVLGQTI
HAALDRAESASGRAYRYSFDMLGEGARTFTDAKRYFDSYATAIDDIGRRAGNMKLPDRPGISVKLSALHPRYDAVNRERV
LIELVPQVIELARKAKAYDLNFTIDAEEADRLELSLDVIDAVLADPGLAGWDGFGLAIQAYQKRAAAVIDHMAALAERLD
RRLMLRLVKGAYWDTEVKRAQERGLDDYPVFTRKAMTDLNYMACARKLLALRPRIFPQFATHNALTIATITELSGGTGGF
EFQRLHGMGDAAHGERLAAHPDVGCRTYAPVGGHRDLLAYLVRRLLENGANSSFVSVAGDPDVPVSDLLRRPATLIGNAE
EARNRHIPLPPDLFGPGRRNSHGVELGCRSVLAATLTDIAGHRREVTASTLIDGVAHAGATRTVVSPIDGSAIGRVVEAD
AATADAAVAAALKGFVAWDRTPASERSARLRRAADLLEARQAAFLALLQDEAGKTLDDGISEVREAVDFLRYYAGEAERL
CGAGETLPGPTGESNVLRLRGRGVFVAISPWNFPLAIFLGQVSAALAAGNAVVAKPAEQTPLIAFEAVRLLHEAGVPASA
LHLVTGDGLIGARLVEAPKVAGVVFTGSTEVARIINRTLAGKDGPIVPLIAETGGINAMIVDATALPEQVSDDVVTSAFR
SAGQRCSALRILFVQEDVADKMIEMIVGAADALKVGDPRDASVHVGPVIDAEAKAKLEAHIRALTGTARVHYAGTAPTRG
TYVAPHVFELKQAADLKDEVFGPVLHVVRFKAGGIDGVLDAIAATGYGLTLGLHTRIDSLVEKVTERLPVGNVYVNRNII
GAVVGVQPFGGHGLSGTGPKAGGPHYLLRFASEQTVTINTSAAGGNAALMTQGE

Sequences:

>Translated_1094_residues
MKDLEDFFVSAVQRAHVSRSRHGLSVKDKAEWRKEPSKRGRSWITQTYPPESAMPAPTSPVSASLPPSPMPPFEAPFAPD
DVALARPLLAQGTLAPEAEARIDALAARLITAIRKGSNAGGVGGIEEVLREYALSTKEGLALMTLAEALLRVPDSATADR
LIEDKLAQGDFLNHDSRSSALLVNASSWALGVTARVIQPGETPEGVLGKLAKRIGLPAVRTATRQAMKVLGNHFVLGQTI
HAALDRAESASGRAYRYSFDMLGEGARTFTDAKRYFDSYATAIDDIGRRAGNMKLPDRPGISVKLSALHPRYDAVNRERV
LIELVPQVIELARKAKAYDLNFTIDAEEADRLELSLDVIDAVLADPGLAGWDGFGLAIQAYQKRAAAVIDHMAALAERLD
RRLMLRLVKGAYWDTEVKRAQERGLDDYPVFTRKAMTDLNYMACARKLLALRPRIFPQFATHNALTIATITELSGGTGGF
EFQRLHGMGDAAHGERLAAHPDVGCRTYAPVGGHRDLLAYLVRRLLENGANSSFVSVAGDPDVPVSDLLRRPATLIGNAE
EARNRHIPLPPDLFGPGRRNSHGVELGCRSVLAATLTDIAGHRREVTASTLIDGVAHAGATRTVVSPIDGSAIGRVVEAD
AATADAAVAAALKGFVAWDRTPASERSARLRRAADLLEARQAAFLALLQDEAGKTLDDGISEVREAVDFLRYYAGEAERL
CGAGETLPGPTGESNVLRLRGRGVFVAISPWNFPLAIFLGQVSAALAAGNAVVAKPAEQTPLIAFEAVRLLHEAGVPASA
LHLVTGDGLIGARLVEAPKVAGVVFTGSTEVARIINRTLAGKDGPIVPLIAETGGINAMIVDATALPEQVSDDVVTSAFR
SAGQRCSALRILFVQEDVADKMIEMIVGAADALKVGDPRDASVHVGPVIDAEAKAKLEAHIRALTGTARVHYAGTAPTRG
TYVAPHVFELKQAADLKDEVFGPVLHVVRFKAGGIDGVLDAIAATGYGLTLGLHTRIDSLVEKVTERLPVGNVYVNRNII
GAVVGVQPFGGHGLSGTGPKAGGPHYLLRFASEQTVTINTSAAGGNAALMTQGE
>Mature_1094_residues
MKDLEDFFVSAVQRAHVSRSRHGLSVKDKAEWRKEPSKRGRSWITQTYPPESAMPAPTSPVSASLPPSPMPPFEAPFAPD
DVALARPLLAQGTLAPEAEARIDALAARLITAIRKGSNAGGVGGIEEVLREYALSTKEGLALMTLAEALLRVPDSATADR
LIEDKLAQGDFLNHDSRSSALLVNASSWALGVTARVIQPGETPEGVLGKLAKRIGLPAVRTATRQAMKVLGNHFVLGQTI
HAALDRAESASGRAYRYSFDMLGEGARTFTDAKRYFDSYATAIDDIGRRAGNMKLPDRPGISVKLSALHPRYDAVNRERV
LIELVPQVIELARKAKAYDLNFTIDAEEADRLELSLDVIDAVLADPGLAGWDGFGLAIQAYQKRAAAVIDHMAALAERLD
RRLMLRLVKGAYWDTEVKRAQERGLDDYPVFTRKAMTDLNYMACARKLLALRPRIFPQFATHNALTIATITELSGGTGGF
EFQRLHGMGDAAHGERLAAHPDVGCRTYAPVGGHRDLLAYLVRRLLENGANSSFVSVAGDPDVPVSDLLRRPATLIGNAE
EARNRHIPLPPDLFGPGRRNSHGVELGCRSVLAATLTDIAGHRREVTASTLIDGVAHAGATRTVVSPIDGSAIGRVVEAD
AATADAAVAAALKGFVAWDRTPASERSARLRRAADLLEARQAAFLALLQDEAGKTLDDGISEVREAVDFLRYYAGEAERL
CGAGETLPGPTGESNVLRLRGRGVFVAISPWNFPLAIFLGQVSAALAAGNAVVAKPAEQTPLIAFEAVRLLHEAGVPASA
LHLVTGDGLIGARLVEAPKVAGVVFTGSTEVARIINRTLAGKDGPIVPLIAETGGINAMIVDATALPEQVSDDVVTSAFR
SAGQRCSALRILFVQEDVADKMIEMIVGAADALKVGDPRDASVHVGPVIDAEAKAKLEAHIRALTGTARVHYAGTAPTRG
TYVAPHVFELKQAADLKDEVFGPVLHVVRFKAGGIDGVLDAIAATGYGLTLGLHTRIDSLVEKVTERLPVGNVYVNRNII
GAVVGVQPFGGHGLSGTGPKAGGPHYLLRFASEQTVTINTSAAGGNAALMTQGE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=487, Percent_Identity=32.8542094455852, Blast_Score=202, Evalue=2e-51,
Organism=Homo sapiens, GI25777736, Length=504, Percent_Identity=31.547619047619, Blast_Score=200, Evalue=5e-51,
Organism=Homo sapiens, GI25777734, Length=504, Percent_Identity=31.547619047619, Blast_Score=200, Evalue=5e-51,
Organism=Homo sapiens, GI153266822, Length=472, Percent_Identity=32.6271186440678, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI25777730, Length=476, Percent_Identity=34.6638655462185, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI238859541, Length=468, Percent_Identity=32.2649572649573, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI21361176, Length=507, Percent_Identity=32.1499013806706, Blast_Score=193, Evalue=1e-48,
Organism=Homo sapiens, GI238814322, Length=478, Percent_Identity=33.2635983263598, Blast_Score=189, Evalue=9e-48,
Organism=Homo sapiens, GI25777724, Length=474, Percent_Identity=32.0675105485232, Blast_Score=187, Evalue=6e-47,
Organism=Homo sapiens, GI21614513, Length=459, Percent_Identity=32.244008714597, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI25777728, Length=424, Percent_Identity=31.8396226415094, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI115387104, Length=460, Percent_Identity=28.695652173913, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI12007648, Length=477, Percent_Identity=29.1404612159329, Blast_Score=157, Evalue=8e-38,
Organism=Homo sapiens, GI4507229, Length=463, Percent_Identity=30.0215982721382, Blast_Score=156, Evalue=9e-38,
Organism=Homo sapiens, GI25777726, Length=473, Percent_Identity=29.8097251585624, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI25777721, Length=476, Percent_Identity=28.9915966386555, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI188035924, Length=477, Percent_Identity=28.5115303983228, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI310128093, Length=382, Percent_Identity=29.3193717277487, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI310128103, Length=382, Percent_Identity=29.3193717277487, Blast_Score=136, Evalue=9e-32,
Organism=Homo sapiens, GI11095441, Length=423, Percent_Identity=27.1867612293144, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI4502043, Length=419, Percent_Identity=27.9236276849642, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI238814371, Length=419, Percent_Identity=27.9236276849642, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI310128091, Length=344, Percent_Identity=30.8139534883721, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI71773324, Length=331, Percent_Identity=28.3987915407855, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI25952152, Length=466, Percent_Identity=27.4678111587983, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI73695881, Length=321, Percent_Identity=28.6604361370716, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI73695879, Length=321, Percent_Identity=28.6604361370716, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI310128087, Length=281, Percent_Identity=28.4697508896797, Blast_Score=97, Evalue=9e-20,
Organism=Homo sapiens, GI206597441, Length=325, Percent_Identity=25.5384615384615, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI206597439, Length=325, Percent_Identity=25.5384615384615, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI22907049, Length=325, Percent_Identity=25.5384615384615, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI310128101, Length=220, Percent_Identity=28.6363636363636, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI310128099, Length=220, Percent_Identity=28.6363636363636, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI301500698, Length=291, Percent_Identity=28.1786941580756, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI73466520, Length=322, Percent_Identity=22.6708074534161, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4557303, Length=322, Percent_Identity=22.6708074534161, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI310128089, Length=246, Percent_Identity=28.8617886178862, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI310128095, Length=234, Percent_Identity=28.6324786324786, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI310128097, Length=171, Percent_Identity=32.1637426900585, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI1787250, Length=1058, Percent_Identity=46.3137996219282, Blast_Score=860, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=464, Percent_Identity=36.2068965517241, Blast_Score=208, Evalue=2e-54,
Organism=Escherichia coli, GI87081896, Length=483, Percent_Identity=32.9192546583851, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1787684, Length=466, Percent_Identity=31.5450643776824, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1787715, Length=466, Percent_Identity=33.2618025751073, Blast_Score=168, Evalue=2e-42,
Organism=Escherichia coli, GI1788042, Length=460, Percent_Identity=30, Blast_Score=162, Evalue=1e-40,
Organism=Escherichia coli, GI1787558, Length=470, Percent_Identity=30, Blast_Score=160, Evalue=5e-40,
Organism=Escherichia coli, GI1786504, Length=463, Percent_Identity=28.9416846652268, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI87082295, Length=482, Percent_Identity=27.5933609958506, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI87081926, Length=457, Percent_Identity=26.0393873085339, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1787653, Length=389, Percent_Identity=24.6786632390745, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=465, Percent_Identity=32.4731182795699, Blast_Score=191, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI133930964, Length=472, Percent_Identity=32.6271186440678, Blast_Score=190, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI115532534, Length=389, Percent_Identity=33.9331619537275, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25144435, Length=479, Percent_Identity=30.8977035490605, Blast_Score=169, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25143874, Length=470, Percent_Identity=29.3617021276596, Blast_Score=169, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=482, Percent_Identity=30.0829875518672, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25143876, Length=470, Percent_Identity=29.3617021276596, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=472, Percent_Identity=30.9322033898305, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17534119, Length=459, Percent_Identity=29.6296296296296, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI32564736, Length=429, Percent_Identity=31.002331002331, Blast_Score=146, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17551164, Length=472, Percent_Identity=28.3898305084746, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI32564151, Length=397, Percent_Identity=30.7304785894207, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71995606, Length=452, Percent_Identity=29.4247787610619, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71995613, Length=409, Percent_Identity=28.8508557457213, Blast_Score=126, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71986308, Length=443, Percent_Identity=28.2167042889391, Blast_Score=123, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71990744, Length=297, Percent_Identity=28.956228956229, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25146391, Length=436, Percent_Identity=24.0825688073394, Blast_Score=93, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=339, Percent_Identity=26.2536873156342, Blast_Score=93, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=436, Percent_Identity=24.0825688073394, Blast_Score=93, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=460, Percent_Identity=23.2608695652174, Blast_Score=83, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=457, Percent_Identity=32.1663019693654, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6324950, Length=453, Percent_Identity=28.9183222958057, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323822, Length=458, Percent_Identity=28.82096069869, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6319478, Length=480, Percent_Identity=28.9583333333333, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323821, Length=459, Percent_Identity=28.7581699346405, Blast_Score=160, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6325196, Length=466, Percent_Identity=28.755364806867, Blast_Score=157, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6321826, Length=442, Percent_Identity=30.0904977375566, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321828, Length=484, Percent_Identity=25.8264462809917, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6323757, Length=325, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362580, Length=485, Percent_Identity=32.5773195876289, Blast_Score=206, Evalue=8e-53,
Organism=Drosophila melanogaster, GI62472918, Length=485, Percent_Identity=32.5773195876289, Blast_Score=206, Evalue=8e-53,
Organism=Drosophila melanogaster, GI62472926, Length=485, Percent_Identity=32.5773195876289, Blast_Score=206, Evalue=8e-53,
Organism=Drosophila melanogaster, GI62472936, Length=485, Percent_Identity=32.5773195876289, Blast_Score=206, Evalue=8e-53,
Organism=Drosophila melanogaster, GI21356737, Length=485, Percent_Identity=32.5773195876289, Blast_Score=206, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24668425, Length=457, Percent_Identity=30.1969365426696, Blast_Score=189, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24668417, Length=457, Percent_Identity=30.1969365426696, Blast_Score=189, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24668413, Length=457, Percent_Identity=30.1969365426696, Blast_Score=189, Evalue=8e-48,
Organism=Drosophila melanogaster, GI20129399, Length=490, Percent_Identity=32.0408163265306, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24650465, Length=484, Percent_Identity=30.7851239669421, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24585660, Length=498, Percent_Identity=27.710843373494, Blast_Score=163, Evalue=5e-40,
Organism=Drosophila melanogaster, GI28571798, Length=448, Percent_Identity=29.6875, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571796, Length=448, Percent_Identity=29.6875, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571794, Length=448, Percent_Identity=29.6875, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571802, Length=448, Percent_Identity=29.6875, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571800, Length=448, Percent_Identity=29.6875, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571806, Length=448, Percent_Identity=29.6875, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24666674, Length=478, Percent_Identity=27.1966527196653, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574525, Length=492, Percent_Identity=24.7967479674797, Blast_Score=136, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24638876, Length=448, Percent_Identity=26.7857142857143, Blast_Score=105, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24638878, Length=448, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281360303, Length=324, Percent_Identity=26.8518518518519, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45552499, Length=328, Percent_Identity=26.8292682926829, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360301, Length=324, Percent_Identity=27.1604938271605, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360299, Length=328, Percent_Identity=27.1341463414634, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360297, Length=328, Percent_Identity=27.1341463414634, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360295, Length=328, Percent_Identity=27.1341463414634, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586250, Length=328, Percent_Identity=27.1341463414634, Blast_Score=93, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 116233; Mature: 116233

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLEDFFVSAVQRAHVSRSRHGLSVKDKAEWRKEPSKRGRSWITQTYPPESAMPAPTSP
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCC
VSASLPPSPMPPFEAPFAPDDVALARPLLAQGTLAPEAEARIDALAARLITAIRKGSNAG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GVGGIEEVLREYALSTKEGLALMTLAEALLRVPDSATADRLIEDKLAQGDFLNHDSRSSA
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCE
LLVNASSWALGVTARVIQPGETPEGVLGKLAKRIGLPAVRTATRQAMKVLGNHFVLGQTI
EEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEHHHHH
HAALDRAESASGRAYRYSFDMLGEGARTFTDAKRYFDSYATAIDDIGRRAGNMKLPDRPG
HHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ISVKLSALHPRYDAVNRERVLIELVPQVIELARKAKAYDLNFTIDAEEADRLELSLDVID
CEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHH
AVLADPGLAGWDGFGLAIQAYQKRAAAVIDHMAALAERLDRRLMLRLVKGAYWDTEVKRA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QERGLDDYPVFTRKAMTDLNYMACARKLLALRPRIFPQFATHNALTIATITELSGGTGGF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHHCCCCEEEEEEEECCCCCCCC
EFQRLHGMGDAAHGERLAAHPDVGCRTYAPVGGHRDLLAYLVRRLLENGANSSFVSVAGD
CHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
PDVPVSDLLRRPATLIGNAEEARNRHIPLPPDLFGPGRRNSHGVELGCRSVLAATLTDIA
CCCCHHHHHHCCHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GHRREVTASTLIDGVAHAGATRTVVSPIDGSAIGRVVEADAATADAAVAAALKGFVAWDR
CCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
TPASERSARLRRAADLLEARQAAFLALLQDEAGKTLDDGISEVREAVDFLRYYAGEAERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
CGAGETLPGPTGESNVLRLRGRGVFVAISPWNFPLAIFLGQVSAALAAGNAVVAKPAEQT
CCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
PLIAFEAVRLLHEAGVPASALHLVTGDGLIGARLVEAPKVAGVVFTGSTEVARIINRTLA
CHHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHC
GKDGPIVPLIAETGGINAMIVDATALPEQVSDDVVTSAFRSAGQRCSALRILFVQEDVAD
CCCCCEEEEEECCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHH
KMIEMIVGAADALKVGDPRDASVHVGPVIDAEAKAKLEAHIRALTGTARVHYAGTAPTRG
HHHHHHHCCHHHHCCCCCCCCCEEECCEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCC
TYVAPHVFELKQAADLKDEVFGPVLHVVRFKAGGIDGVLDAIAATGYGLTLGLHTRIDSL
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEHHHHHHHH
VEKVTERLPVGNVYVNRNIIGAVVGVQPFGGHGLSGTGPKAGGPHYLLRFASEQTVTINT
HHHHHHHCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEE
SAAGGNAALMTQGE
CCCCCCEEEEECCC
>Mature Secondary Structure
MKDLEDFFVSAVQRAHVSRSRHGLSVKDKAEWRKEPSKRGRSWITQTYPPESAMPAPTSP
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCC
VSASLPPSPMPPFEAPFAPDDVALARPLLAQGTLAPEAEARIDALAARLITAIRKGSNAG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GVGGIEEVLREYALSTKEGLALMTLAEALLRVPDSATADRLIEDKLAQGDFLNHDSRSSA
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCE
LLVNASSWALGVTARVIQPGETPEGVLGKLAKRIGLPAVRTATRQAMKVLGNHFVLGQTI
EEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEHHHHH
HAALDRAESASGRAYRYSFDMLGEGARTFTDAKRYFDSYATAIDDIGRRAGNMKLPDRPG
HHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ISVKLSALHPRYDAVNRERVLIELVPQVIELARKAKAYDLNFTIDAEEADRLELSLDVID
CEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHH
AVLADPGLAGWDGFGLAIQAYQKRAAAVIDHMAALAERLDRRLMLRLVKGAYWDTEVKRA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QERGLDDYPVFTRKAMTDLNYMACARKLLALRPRIFPQFATHNALTIATITELSGGTGGF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHHCCCCEEEEEEEECCCCCCCC
EFQRLHGMGDAAHGERLAAHPDVGCRTYAPVGGHRDLLAYLVRRLLENGANSSFVSVAGD
CHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
PDVPVSDLLRRPATLIGNAEEARNRHIPLPPDLFGPGRRNSHGVELGCRSVLAATLTDIA
CCCCHHHHHHCCHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GHRREVTASTLIDGVAHAGATRTVVSPIDGSAIGRVVEADAATADAAVAAALKGFVAWDR
CCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
TPASERSARLRRAADLLEARQAAFLALLQDEAGKTLDDGISEVREAVDFLRYYAGEAERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
CGAGETLPGPTGESNVLRLRGRGVFVAISPWNFPLAIFLGQVSAALAAGNAVVAKPAEQT
CCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
PLIAFEAVRLLHEAGVPASALHLVTGDGLIGARLVEAPKVAGVVFTGSTEVARIINRTLA
CHHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHC
GKDGPIVPLIAETGGINAMIVDATALPEQVSDDVVTSAFRSAGQRCSALRILFVQEDVAD
CCCCCEEEEEECCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHH
KMIEMIVGAADALKVGDPRDASVHVGPVIDAEAKAKLEAHIRALTGTARVHYAGTAPTRG
HHHHHHHCCHHHHCCCCCCCCCEEECCEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCC
TYVAPHVFELKQAADLKDEVFGPVLHVVRFKAGGIDGVLDAIAATGYGLTLGLHTRIDSL
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEHHHHHHHH
VEKVTERLPVGNVYVNRNIIGAVVGVQPFGGHGLSGTGPKAGGPHYLLRFASEQTVTINT
HHHHHHHCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEE
SAAGGNAALMTQGE
CCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]