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The map label for this gene is yfhC

Identifier: 15836532

GI number: 15836532

Start: 1149832

End: 1150278

Strand: Direct

Name: yfhC

Synonym: CPj1001

Alternate gene names: 15836532

Gene position: 1149832-1150278 (Clockwise)

Preceding gene: 15836529

Following gene: 15836533

Centisome position: 93.74

GC content: 44.52

Gene sequence:

>447_bases
ATGCAACAAGCCTTCAAAGAAGCGCGTAAGGCATATGATCAGGATGAAGTTCCTGTGGGCTGTGTGATTGTCAAAGACGA
TAAGATCATTGCTCGTGCGCATAATTCAGTGGAGAAGCTTAAGGATGCTACAGCCCATGCTGAAATTTTATGTATAGGGT
CTGCGGCCCAAGATTTAGATAATTGGCGTTTGTTGGATACCGTCCTTTACTGTACGTTAGAGCCGTGTTTGATGTGTGCG
GGTGCGATTCAATTGGCTAGAATTCCTAGAATTGTCTGGGCAGCTCCAGACGTGCGTTTAGGAGCAGGAGGAAGTTGGGT
CAATATCTTTACTGAAGAGCATCCTTTCCATACGGTTTCTTGTACTGGGGGCGTGTGTAGCGAGGAGGCAGAGCATCTAA
TGAAAAAATTTTTTGTAGAAAAGCGCAGAGAGAAAAGTGAAAAATAA

Upstream 100 bases:

>100_bases
TTGTTATTTTTTTTGTTTTTAGAACTCATAATGGAATAAATAATATTATTTAGAATTGGGTGGAGAGAAGCTTATCAATA
TGGAAAAAGATATTTTTTTT

Downstream 100 bases:

>100_bases
AATTGTTACATTATTAGATCAGCTCTACGAGGATCAGGAGTCACGACTTCAGAAGTTAGGAGAGGAAATTGTTCCTAACC
TCACTCCTGAAGATTTATTG

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MQQAFKEARKAYDQDEVPVGCVIVKDDKIIARAHNSVEKLKDATAHAEILCIGSAAQDLDNWRLLDTVLYCTLEPCLMCA
GAIQLARIPRIVWAAPDVRLGAGGSWVNIFTEEHPFHTVSCTGGVCSEEAEHLMKKFFVEKRREKSEK

Sequences:

>Translated_148_residues
MQQAFKEARKAYDQDEVPVGCVIVKDDKIIARAHNSVEKLKDATAHAEILCIGSAAQDLDNWRLLDTVLYCTLEPCLMCA
GAIQLARIPRIVWAAPDVRLGAGGSWVNIFTEEHPFHTVSCTGGVCSEEAEHLMKKFFVEKRREKSEK
>Mature_148_residues
MQQAFKEARKAYDQDEVPVGCVIVKDDKIIARAHNSVEKLKDATAHAEILCIGSAAQDLDNWRLLDTVLYCTLEPCLMCA
GAIQLARIPRIVWAAPDVRLGAGGSWVNIFTEEHPFHTVSCTGGVCSEEAEHLMKKFFVEKRREKSEK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=149, Percent_Identity=36.241610738255, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI145693172, Length=149, Percent_Identity=39.5973154362416, Blast_Score=118, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17541138, Length=163, Percent_Identity=33.1288343558282, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=118, Percent_Identity=38.135593220339, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=167, Percent_Identity=28.1437125748503, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=94, Percent_Identity=38.2978723404255, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355527, Length=144, Percent_Identity=36.8055555555556, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16529; Mature: 16529

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQAFKEARKAYDQDEVPVGCVIVKDDKIIARAHNSVEKLKDATAHAEILCIGSAAQDLD
CCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCC
NWRLLDTVLYCTLEPCLMCAGAIQLARIPRIVWAAPDVRLGAGGSWVNIFTEEHPFHTVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCEEEEEECCCCCEEEE
CTGGVCSEEAEHLMKKFFVEKRREKSEK
CCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQAFKEARKAYDQDEVPVGCVIVKDDKIIARAHNSVEKLKDATAHAEILCIGSAAQDLD
CCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCC
NWRLLDTVLYCTLEPCLMCAGAIQLARIPRIVWAAPDVRLGAGGSWVNIFTEEHPFHTVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCEEEEEECCCCCEEEE
CTGGVCSEEAEHLMKKFFVEKRREKSEK
CCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]