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The map label for this gene is murG

Identifier: 15836437

GI number: 15836437

Start: 1035647

End: 1036720

Strand: Direct

Name: murG

Synonym: CPj0904

Alternate gene names: 15836437

Gene position: 1035647-1036720 (Clockwise)

Preceding gene: 15836436

Following gene: 15836438

Centisome position: 84.43

GC content: 42.74

Gene sequence:

>1074_bases
ATGATGAAGAAAATTCGAAAAGTAGCCTTGGCTGTAGGAGGTTCAGGAGGCCACATTGTCCCAGCTCTCTCGGTAAAGGA
AGCTTTTTCTCGTGAAGGAATAGACGTATTACTACTAGGGAAAGGTCTCAAGAACCATCCTTCTTTGCAACAGGGAATCA
GCTATCGGGAAATCCCCTCAGGACTTCCTACAGTCCTTAATCCCATAAAGATCATGAGCAGGACCCTTTCTCTATGTTCA
GGATACCTGAAAGCAAGAAAGGAACTTAAAATTTTTGACCCTGACCTGGTCATAGGATTTGGGAGCTACCACTCTCTTCC
CGTGTTGCTCGCAGGACTGTCCCATAAAATTCCCTTATTTCTACACGAACAAAATCTAGTTCCTGGAAAAGTAAATCAAT
TGTTTTCCCGCTATGCTCGAGGTATTGGAGTGAATTTCTCCCCCGTTACTAAACACTTCCGCTGCCCCGCAGAAGAGGTC
TTCCTTCCTAAACGAAGCTTCTCCTTAGGAAGCCCTATGATGAAGCGATGTACAAATCATACCCCTACAATCTGTGTTGT
TGGAGGTTCTCAGGGAGCACAGATATTAAATACTTGTGTTCCCCAAGCTCTTGTCAAGCTAGTCAATAAGTACCCAAATA
TGTACGTCCATCATATTGTAGGACCTAAAAGTGATGTTATGAAGGTGCAACATGTTTACAATCGTGGAGAGGTCCTCTGC
TGTGTGAAGCCGTTCGAAGAGCAACTCCTAGATGTCTTGCTTGCCGCAGATTTGGTCATCAGTAGGGCAGGAGCCACAAT
TTTAGAAGAAATTCTTTGGGCAAAAGTTCCCGGAATTTTAATTCCCTATCCAGGAGCTTATGGACATCAGGAAGTTAATG
CTAAATTCTTTGTAGACGTCTTAGAAGGGGGAACTATGATCCTAGAAAAAGAATTAACAGAGAAGCTATTAGTAGAAAAA
GTAACGTTTGCTTTAGACTCCCATAACAGAGAAAAACAACGCAATTCCCTAGCGGCGTATAGTCAGCAAAGGTCAACAAA
AACATTCCATGCATTCATTTGTGAATGCTTATAG

Upstream 100 bases:

>100_bases
GGCCTGCTTCCTAGTAAAGGAGTCAACCTTCCTTTTTTTAGCCAAGGAGGGTCCTCTCTTATCGCAAATATGTGTGGAGT
CACGTTGTTATTGAAGGTAT

Downstream 100 bases:

>100_bases
GTTCATTATATGAAGGGAACTCCTCAGTATCATTTTATCGGTATCGGTGGTATAGGAATGAGCGCTTTAGCTCATATTTT
GCTTGATCGTGGCTATGAGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MMKKIRKVALAVGGSGGHIVPALSVKEAFSREGIDVLLLGKGLKNHPSLQQGISYREIPSGLPTVLNPIKIMSRTLSLCS
GYLKARKELKIFDPDLVIGFGSYHSLPVLLAGLSHKIPLFLHEQNLVPGKVNQLFSRYARGIGVNFSPVTKHFRCPAEEV
FLPKRSFSLGSPMMKRCTNHTPTICVVGGSQGAQILNTCVPQALVKLVNKYPNMYVHHIVGPKSDVMKVQHVYNRGEVLC
CVKPFEEQLLDVLLAADLVISRAGATILEEILWAKVPGILIPYPGAYGHQEVNAKFFVDVLEGGTMILEKELTEKLLVEK
VTFALDSHNREKQRNSLAAYSQQRSTKTFHAFICECL

Sequences:

>Translated_357_residues
MMKKIRKVALAVGGSGGHIVPALSVKEAFSREGIDVLLLGKGLKNHPSLQQGISYREIPSGLPTVLNPIKIMSRTLSLCS
GYLKARKELKIFDPDLVIGFGSYHSLPVLLAGLSHKIPLFLHEQNLVPGKVNQLFSRYARGIGVNFSPVTKHFRCPAEEV
FLPKRSFSLGSPMMKRCTNHTPTICVVGGSQGAQILNTCVPQALVKLVNKYPNMYVHHIVGPKSDVMKVQHVYNRGEVLC
CVKPFEEQLLDVLLAADLVISRAGATILEEILWAKVPGILIPYPGAYGHQEVNAKFFVDVLEGGTMILEKELTEKLLVEK
VTFALDSHNREKQRNSLAAYSQQRSTKTFHAFICECL
>Mature_357_residues
MMKKIRKVALAVGGSGGHIVPALSVKEAFSREGIDVLLLGKGLKNHPSLQQGISYREIPSGLPTVLNPIKIMSRTLSLCS
GYLKARKELKIFDPDLVIGFGSYHSLPVLLAGLSHKIPLFLHEQNLVPGKVNQLFSRYARGIGVNFSPVTKHFRCPAEEV
FLPKRSFSLGSPMMKRCTNHTPTICVVGGSQGAQILNTCVPQALVKLVNKYPNMYVHHIVGPKSDVMKVQHVYNRGEVLC
CVKPFEEQLLDVLLAADLVISRAGATILEEILWAKVPGILIPYPGAYGHQEVNAKFFVDVLEGGTMILEKELTEKLLVEK
VTFALDSHNREKQRNSLAAYSQQRSTKTFHAFICECL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=350, Percent_Identity=29.1428571428571, Blast_Score=111, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CHLPN (Q9Z702)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C72022
- PIR:   F86603
- RefSeq:   NP_225099.1
- RefSeq:   NP_300961.1
- RefSeq:   NP_445499.1
- RefSeq:   NP_877208.1
- ProteinModelPortal:   Q9Z702
- SMR:   Q9Z702
- GeneID:   1467615
- GeneID:   895672
- GeneID:   919669
- GeneID:   963428
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0962
- KEGG:   cpn:CPn0904
- KEGG:   cpt:CpB0936
- TIGR:   CP_0962
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- ProtClustDB:   PRK00726
- BioCyc:   CPNE115711:CP_0962-MONOMER
- BioCyc:   CPNE115713:CPN0904-MONOMER
- BioCyc:   CPNE138677:CPJ0904-MONOMER
- BioCyc:   CPNE182082:CPB0936-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39421; Mature: 39421

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKIRKVALAVGGSGGHIVPALSVKEAFSREGIDVLLLGKGLKNHPSLQQGISYREIPS
CHHHHHHHHHEECCCCCCEEECHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCHHHCCC
GLPTVLNPIKIMSRTLSLCSGYLKARKELKIFDPDLVIGFGSYHSLPVLLAGLSHKIPLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCHHHHHHHCCCCCCEEE
LHEQNLVPGKVNQLFSRYARGIGVNFSPVTKHFRCPAEEVFLPKRSFSLGSPMMKRCTNH
EECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHCCC
TPTICVVGGSQGAQILNTCVPQALVKLVNKYPNMYVHHIVGPKSDVMKVQHVYNRGEVLC
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEE
CVKPFEEQLLDVLLAADLVISRAGATILEEILWAKVPGILIPYPGAYGHQEVNAKFFVDV
EECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHEEEE
LEGGTMILEKELTEKLLVEKVTFALDSHNREKQRNSLAAYSQQRSTKTFHAFICECL
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MMKKIRKVALAVGGSGGHIVPALSVKEAFSREGIDVLLLGKGLKNHPSLQQGISYREIPS
CHHHHHHHHHEECCCCCCEEECHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCHHHCCC
GLPTVLNPIKIMSRTLSLCSGYLKARKELKIFDPDLVIGFGSYHSLPVLLAGLSHKIPLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCHHHHHHHCCCCCCEEE
LHEQNLVPGKVNQLFSRYARGIGVNFSPVTKHFRCPAEEVFLPKRSFSLGSPMMKRCTNH
EECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHCCC
TPTICVVGGSQGAQILNTCVPQALVKLVNKYPNMYVHHIVGPKSDVMKVQHVYNRGEVLC
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEE
CVKPFEEQLLDVLLAADLVISRAGATILEEILWAKVPGILIPYPGAYGHQEVNAKFFVDV
EECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHEEEE
LEGGTMILEKELTEKLLVEKVTFALDSHNREKQRNSLAAYSQQRSTKTFHAFICECL
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362