Click here to switch to the map view.

The map label for this gene is ygcA

Identifier: 15836418

GI number: 15836418

Start: 1008751

End: 1009956

Strand: Reverse

Name: ygcA

Synonym: CPj0885

Alternate gene names: 15836418

Gene position: 1009956-1008751 (Counterclockwise)

Preceding gene: 15836419

Following gene: 15836417

Centisome position: 82.34

GC content: 40.71

Gene sequence:

>1206_bases
ATGTCTACCATGCAAAATTGTCCACATTTTGGTGTATGTGGAGGATGCTCGTTTCCTCAGTCCAATTATTCTGACTCCTT
AAAGAAAAAGGAAGAACTCCTTCATCAGTTATTCGCTCCTTTAGTTCCCTCGGATATGATTGCTCCTATCATCCCATGTT
CTCCCTCTTTAAGAGGAAGAAATAAAATGGAATTCTCCTTTTTTCAAACTTATGAAGGAGAAAAAAGTTTAGGATTCATC
AGCTCTACAAAACCAAAGAAAGGAATTCCAGTGACTACATGTCTGCTTATCCATGAGCAGACTATGGATATTTTAAAACT
CACTCGCGAATGGTGGGATAAGCACCCAGAGCTTATGGCGTACTTCCCCCCTAAAAACAAAGGCTCGTTATGCACACTCA
CCGTCCGTACGGGGAGCCCGCAGCAAAACTTTATGGTGATCCTAACAACATCAGGAACTCCAGAATATAGGGTAAACGAA
GCCTGTATAGATGAATGGAAAGAGATTCTCCTATCGTCTTCTCTAAACATAGCATCGATCTATTGGGAAGAAAAGGTAGC
TGCACGTGGGATTTCTACATATTATGAAACTAAACTGCTATACGGAGCCCCCTCGATACAGCAAAAACTGTCCTTACCTA
GTGACGGTAACTCTGCCTCTTTTAGTTTGCGTCCCAGAAGTTTCTTCCAACCTCAGATTACTCAGGCAGCGAAAATTATA
GAAACTGCGAAAGAGTTTATAAACCCCGAGGGTTCGGAAACGCTTCTTGATCTCTATTGTGGAGCAGGAACTATAGGGAT
TATGCTCTCTCCCTATGTCAAAAATGTGATTGGCGTTGAGATTATTCCTGATGCTGTAGCTTCGGCTCAGGAGAACATCA
AAGCGAATAACAAAGAAGATTGCGTAGAAGTCTATTTAGAAGATGCGAAAGCGTTCTGCAAAAGGAATGAAAATTGTAAA
GCTCCTGATGTCATTATTATTGATCCCCCACGTTGTGGTATGCAAAGTAAAGTACTTAAATATATTTTACGTATAGGATC
TCCAAAAATTGTCTATATCTCTTGCAACCCTAAAACACAGTTTCAAGAGTGCGCGGACCTAATCTCTGGGGGATATCGCA
TAAAAAAGATGCAGCCTATTGACCAATTTCCCTATTCGACGCACCTAGAAAATATTATTTTACTAGAAAGAGAGATCGAT
CTCTAG

Upstream 100 bases:

>100_bases
TTCAAGTATCTCATCTAGGGATTCGAAATGAAGGTCCTTGTGAATTGTTGTCTAGTTCTCAGATTACCTCTCTAACAAAA
ACTAAGCTTCTATCTTAACT

Downstream 100 bases:

>100_bases
GAAAAGCATTGAATGCTCGCTTCCTATTATGATAATCTTACTTCGAATTAACCCAAGTTAAGGTGATTGCATGCTTTCTC
GTATAGTGACATGTTTTCTA

Product: rRNA methyltransferse

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSTMQNCPHFGVCGGCSFPQSNYSDSLKKKEELLHQLFAPLVPSDMIAPIIPCSPSLRGRNKMEFSFFQTYEGEKSLGFI
SSTKPKKGIPVTTCLLIHEQTMDILKLTREWWDKHPELMAYFPPKNKGSLCTLTVRTGSPQQNFMVILTTSGTPEYRVNE
ACIDEWKEILLSSSLNIASIYWEEKVAARGISTYYETKLLYGAPSIQQKLSLPSDGNSASFSLRPRSFFQPQITQAAKII
ETAKEFINPEGSETLLDLYCGAGTIGIMLSPYVKNVIGVEIIPDAVASAQENIKANNKEDCVEVYLEDAKAFCKRNENCK
APDVIIIDPPRCGMQSKVLKYILRIGSPKIVYISCNPKTQFQECADLISGGYRIKKMQPIDQFPYSTHLENIILLEREID
L

Sequences:

>Translated_401_residues
MSTMQNCPHFGVCGGCSFPQSNYSDSLKKKEELLHQLFAPLVPSDMIAPIIPCSPSLRGRNKMEFSFFQTYEGEKSLGFI
SSTKPKKGIPVTTCLLIHEQTMDILKLTREWWDKHPELMAYFPPKNKGSLCTLTVRTGSPQQNFMVILTTSGTPEYRVNE
ACIDEWKEILLSSSLNIASIYWEEKVAARGISTYYETKLLYGAPSIQQKLSLPSDGNSASFSLRPRSFFQPQITQAAKII
ETAKEFINPEGSETLLDLYCGAGTIGIMLSPYVKNVIGVEIIPDAVASAQENIKANNKEDCVEVYLEDAKAFCKRNENCK
APDVIIIDPPRCGMQSKVLKYILRIGSPKIVYISCNPKTQFQECADLISGGYRIKKMQPIDQFPYSTHLENIILLEREID
L
>Mature_400_residues
STMQNCPHFGVCGGCSFPQSNYSDSLKKKEELLHQLFAPLVPSDMIAPIIPCSPSLRGRNKMEFSFFQTYEGEKSLGFIS
STKPKKGIPVTTCLLIHEQTMDILKLTREWWDKHPELMAYFPPKNKGSLCTLTVRTGSPQQNFMVILTTSGTPEYRVNEA
CIDEWKEILLSSSLNIASIYWEEKVAARGISTYYETKLLYGAPSIQQKLSLPSDGNSASFSLRPRSFFQPQITQAAKIIE
TAKEFINPEGSETLLDLYCGAGTIGIMLSPYVKNVIGVEIIPDAVASAQENIKANNKEDCVEVYLEDAKAFCKRNENCKA
PDVIIIDPPRCGMQSKVLKYILRIGSPKIVYISCNPKTQFQECADLISGGYRIKKMQPIDQFPYSTHLENIILLEREIDL

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family

Homologues:

Organism=Homo sapiens, GI34222389, Length=370, Percent_Identity=27.2972972972973, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI51173878, Length=370, Percent_Identity=27.2972972972973, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI269784680, Length=389, Percent_Identity=24.4215938303342, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI269784676, Length=389, Percent_Identity=24.4215938303342, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI20149688, Length=389, Percent_Identity=24.4215938303342, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI269784678, Length=285, Percent_Identity=24.9122807017544, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789148, Length=400, Percent_Identity=25.25, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790403, Length=401, Percent_Identity=25.1870324189526, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787083, Length=193, Percent_Identity=25.9067357512953, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71997438, Length=213, Percent_Identity=29.5774647887324, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666579, Length=431, Percent_Identity=25.5220417633411, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y885_CHLPN (Q9Z721)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   A72023
- PIR:   C86601
- RefSeq:   NP_225080.1
- RefSeq:   NP_300942.1
- RefSeq:   NP_445518.1
- RefSeq:   NP_877186.1
- ProteinModelPortal:   Q9Z721
- SMR:   Q9Z721
- GeneID:   1467593
- GeneID:   895438
- GeneID:   919649
- GeneID:   963449
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0981
- KEGG:   cpj:CPj0885
- KEGG:   cpn:CPn0885
- KEGG:   cpt:CpB0914
- TIGR:   CP_0981
- HOGENOM:   HBG690163
- OMA:   NEACIDE
- PhylomeDB:   Q9Z721
- ProtClustDB:   CLSK871573
- BioCyc:   CPNE115711:CP_0981-MONOMER
- BioCyc:   CPNE115713:CPN0885-MONOMER
- BioCyc:   CPNE138677:CPJ0885-MONOMER
- BioCyc:   CPNE182082:CPB0914-MONOMER
- InterPro:   IPR010280

Pfam domain/function: PF05958 tRNA_U5-meth_tr

EC number: NA

Molecular weight: Translated: 44971; Mature: 44840

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 355-355 BINDING 230-230 BINDING 259-259 BINDING 280-280 BINDING 328-328

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMQNCPHFGVCGGCSFPQSNYSDSLKKKEELLHQLFAPLVPSDMIAPIIPCSPSLRGR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
NKMEFSFFQTYEGEKSLGFISSTKPKKGIPVTTCLLIHEQTMDILKLTREWWDKHPELMA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEEE
YFPPKNKGSLCTLTVRTGSPQQNFMVILTTSGTPEYRVNEACIDEWKEILLSSSLNIASI
ECCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
YWEEKVAARGISTYYETKLLYGAPSIQQKLSLPSDGNSASFSLRPRSFFQPQITQAAKII
EHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCCEEEECCHHHCCHHHHHHHHHH
ETAKEFINPEGSETLLDLYCGAGTIGIMLSPYVKNVIGVEIIPDAVASAQENIKANNKED
HHHHHHHCCCCCHHHHHHHCCCCHHHEEECHHHHHHHCCEECCHHHHHHHHHHCCCCHHH
CVEVYLEDAKAFCKRNENCKAPDVIIIDPPRCGMQSKVLKYILRIGSPKIVYISCNPKTQ
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHH
FQECADLISGGYRIKKMQPIDQFPYSTHLENIILLEREIDL
HHHHHHHHHCCEEEEECCCHHCCCCHHCCCEEEEEEEECCC
>Mature Secondary Structure 
STMQNCPHFGVCGGCSFPQSNYSDSLKKKEELLHQLFAPLVPSDMIAPIIPCSPSLRGR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
NKMEFSFFQTYEGEKSLGFISSTKPKKGIPVTTCLLIHEQTMDILKLTREWWDKHPELMA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEEE
YFPPKNKGSLCTLTVRTGSPQQNFMVILTTSGTPEYRVNEACIDEWKEILLSSSLNIASI
ECCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
YWEEKVAARGISTYYETKLLYGAPSIQQKLSLPSDGNSASFSLRPRSFFQPQITQAAKII
EHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCCEEEECCHHHCCHHHHHHHHHH
ETAKEFINPEGSETLLDLYCGAGTIGIMLSPYVKNVIGVEIIPDAVASAQENIKANNKED
HHHHHHHCCCCCHHHHHHHCCCCHHHEEECHHHHHHHCCEECCHHHHHHHHHHCCCCHHH
CVEVYLEDAKAFCKRNENCKAPDVIIIDPPRCGMQSKVLKYILRIGSPKIVYISCNPKTQ
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHH
FQECADLISGGYRIKKMQPIDQFPYSTHLENIILLEREIDL
HHHHHHHHHCCEEEEECCCHHCCCCHHCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362