Click here to switch to the map view.

The map label for this gene is mreB

Identifier: 15836383

GI number: 15836383

Start: 964614

End: 965714

Strand: Direct

Name: mreB

Synonym: CPj0850

Alternate gene names: 15836383

Gene position: 964614-965714 (Clockwise)

Preceding gene: 15836382

Following gene: 15836384

Centisome position: 78.64

GC content: 43.23

Gene sequence:

>1101_bases
ATGAGTCCACATCGCAATCTGTTTAAACTTAAGAATTTTTCCAATCGCCTTTACAACAGGGCTTTGGGTCGTTTCGACAA
GGTCTTTAATTTTTTTTCTGGTAATGTTGGCATTGATTTAGGCACTGCAAACACTTTGGTTTATGTCCGAGGTCGGGGTA
TTGTTCTTAGTGAACCTTCTGTAGTTGCTGTGGATGCACAGACGCATGCAGTGCTTGCTGTAGGGCATAAGGCGAAAGCG
ATGTTGGGTAAGACGCCCAGAAAGATTATGGCAGTGCGTCCTATGAAGGATGGGGTAATTGCTGATTTTGAGATTGCTGA
GGGCATGTTAAAGGCTTTAATTAAACGTGTAACTCCTTCTCGTAGTGTTTTTCGCCCAAGAATTTTAATTGCTGTTCCTT
CTGGGATTACTGGAGTAGAAAAACGTGCTGTTGAAGATTCTGCATTACATGCTGGGGCTCAGGAAGTAATCTTAATTGAA
GAACCTATGGCTGCTGCGATAGGTGTGGATCTGCCTGTTCATGAGCCTGCAGCGAGTATGATTATTGATATTGGAGGAGG
CACTACCGAGATTGCTATTATTTCTTTGGGAGGAATTGTTGAATCTCGTTCCTTGCGTATTGCTGGGGACGAATTTGATG
AGTGTATCATTAACTACATGCGTCGTACGTACAATTTAATGATAGGTCCTCGTACTGCTGAAGAAATCAAGATTACCATT
GGCTCGGCCTATCCTTTAGGGGATCAGGAGTTGGAGATGGAAGTTCGAGGTCGTGATCAGGTGGCGGGCTTGCCGATTAC
CAAGCGTATTAATTCTGTGGAGATTAGAGAGTGTTTGGCTGAACCTATTCAGCAGATCATAGAATGTGTACGTTTGACAT
TAGAGAAGTGTCCACCAGAACTTTCTGCTGATTTAGTAGAACGTGGTATGGTTTTAGCTGGAGGGGGCGCTTTAATTAAG
GGATTAGATAAGGCTTTGAGTAAGAACACAGGACTTTCTGTGATTACAGCACCGCATCCTTTGCTGGCAGTTTGTTTAGG
AACCGGGAAAGCTTTGGAACATTTAGATCAGTTTAAGAAGCGTAAAGGGAATTTGGTATAG

Upstream 100 bases:

>100_bases
AGGAAAAAGAGCCTTGTAAAGAAAGTGATTAACTCTGATGATGAGGTTGTATCCAAGTTAACTTGGGAAGAAGTATTGGA
ATTGCTGCAGATATGATTTT

Downstream 100 bases:

>100_bases
TCATGGTATGGAGCACCAACATCAAGCATGAAGGTCTGAAATCTTGGATTGATGAGGTTGCTAAATTAACGACTCCGAAG
GACATACGTCTTTGTGATGG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSPHRNLFKLKNFSNRLYNRALGRFDKVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPSVVAVDAQTHAVLAVGHKAKA
MLGKTPRKIMAVRPMKDGVIADFEIAEGMLKALIKRVTPSRSVFRPRILIAVPSGITGVEKRAVEDSALHAGAQEVILIE
EPMAAAIGVDLPVHEPAASMIIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPELSADLVERGMVLAGGGALIK
GLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQFKKRKGNLV

Sequences:

>Translated_366_residues
MSPHRNLFKLKNFSNRLYNRALGRFDKVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPSVVAVDAQTHAVLAVGHKAKA
MLGKTPRKIMAVRPMKDGVIADFEIAEGMLKALIKRVTPSRSVFRPRILIAVPSGITGVEKRAVEDSALHAGAQEVILIE
EPMAAAIGVDLPVHEPAASMIIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPELSADLVERGMVLAGGGALIK
GLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQFKKRKGNLV
>Mature_365_residues
SPHRNLFKLKNFSNRLYNRALGRFDKVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPSVVAVDAQTHAVLAVGHKAKAM
LGKTPRKIMAVRPMKDGVIADFEIAEGMLKALIKRVTPSRSVFRPRILIAVPSGITGVEKRAVEDSALHAGAQEVILIEE
PMAAAIGVDLPVHEPAASMIIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITIG
SAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPELSADLVERGMVLAGGGALIKG
LDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQFKKRKGNLV

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=338, Percent_Identity=57.1005917159763, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI1788875, Length=228, Percent_Identity=28.0701754385965, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 39540; Mature: 39409

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPHRNLFKLKNFSNRLYNRALGRFDKVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCEEEEECCC
VVAVDAQTHAVLAVGHKAKAMLGKTPRKIMAVRPMKDGVIADFEIAEGMLKALIKRVTPS
EEEEECCCEEEEEECCHHHHHHCCCCCCEEEECCCCCCCEECHHHHHHHHHHHHHHCCCC
RSVFRPRILIAVPSGITGVEKRAVEDSALHAGAQEVILIEEPMAAAIGVDLPVHEPAASM
CHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCCCCCCE
IIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
EEECCCCCEEEEEEEECCEEECCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEE
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPE
ECCCCCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSADLVERGMVLAGGGALIKGLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQFKK
CHHHHHHCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCCEEHHHHCCCHHHHHHHHHHH
RKGNLV
HCCCCC
>Mature Secondary Structure 
SPHRNLFKLKNFSNRLYNRALGRFDKVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCEEEEECCC
VVAVDAQTHAVLAVGHKAKAMLGKTPRKIMAVRPMKDGVIADFEIAEGMLKALIKRVTPS
EEEEECCCEEEEEECCHHHHHHCCCCCCEEEECCCCCCCEECHHHHHHHHHHHHHHCCCC
RSVFRPRILIAVPSGITGVEKRAVEDSALHAGAQEVILIEEPMAAAIGVDLPVHEPAASM
CHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCCCCCCE
IIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
EEECCCCCEEEEEEEECCEEECCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEE
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPE
ECCCCCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSADLVERGMVLAGGGALIKGLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQFKK
CHHHHHHCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCCEEHHHHCCCHHHHHHHHHHH
RKGNLV
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]