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The map label for this gene is yggV

Identifier: 15836308

GI number: 15836308

Start: 872732

End: 873352

Strand: Reverse

Name: yggV

Synonym: CPj0775

Alternate gene names: 15836308

Gene position: 873352-872732 (Counterclockwise)

Preceding gene: 15836312

Following gene: 15836305

Centisome position: 71.2

GC content: 41.38

Gene sequence:

>621_bases
ATGAAAATTGTGATTGCTAGTTCTCATGGTTATAAAATACGAGAAACCAAGACTTTTTTAAAGCGTTTAGGTGATTTCGA
TATTTTTTCTCTTTCTGATTTTCCTGACTATAAACTTCCCCAAGAACAGGAAGATTCTATAACGGCGAACGCCCTTACTA
AAGGGATTCACGCTGCCAATCATTTGGGTTGCTGGGTCATTGCGGATGATACGATGTTACGCGTCCCCGCTTTAAATGGT
CTTCCGGGTCCTTTATCTGCGAACTTTGCTGGTGTAGGTGCGTATGATAAAGATCATCGAAAAAAGCTGCTTGATCTTAT
GTCGTCTTTGGAAAGCCTCGTAGACCGTTCTGCGTACTTCGAGTGTTGTGTAGTTTTAGTCTCCCCTAATCAGGAGATTT
TTAAAACGTATGGGATATGCGAGGGCTACATCAGCCATCAAGAAAAAGGTTCTTCAGGGTTCGGCTACGACCCTATCTTT
GTAAAATATGATTACAAACAAACATTTGCCGAGCTTAGTGAAGATGTGAAAAATCAAGTTTCTCACAGAGCAAAGGCATT
GCAAAAACTCGCCCCTCACCTGCAAAGCTTATTTGAAAAACACCTACTCACTAGGGACTAG

Upstream 100 bases:

>100_bases
ACTTTAACTACAAAGATTTTCATCGGCTAATAATTGCGCATTACGCTTGCTGACTCTATCTTGTTAAAACTTTATAATTT
CAAAAGATTAAGAAAGATTC

Downstream 100 bases:

>100_bases
TGTTCGCAAAGATTGCTCCAAGCAACCACGAATTTCTCGCATTTCTGCTAACAGAGCTTCTGCTCGTAAAAAATCCGCTT
CCAAATTAGCAACCGAGGGC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQEDSITANALTKGIHAANHLGCWVIADDTMLRVPALNG
LPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYFECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIF
VKYDYKQTFAELSEDVKNQVSHRAKALQKLAPHLQSLFEKHLLTRD

Sequences:

>Translated_206_residues
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQEDSITANALTKGIHAANHLGCWVIADDTMLRVPALNG
LPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYFECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIF
VKYDYKQTFAELSEDVKNQVSHRAKALQKLAPHLQSLFEKHLLTRD
>Mature_206_residues
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQEDSITANALTKGIHAANHLGCWVIADDTMLRVPALNG
LPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYFECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIF
VKYDYKQTFAELSEDVKNQVSHRAKALQKLAPHLQSLFEKHLLTRD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=202, Percent_Identity=32.6732673267327, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31657144, Length=167, Percent_Identity=34.1317365269461, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789324, Length=199, Percent_Identity=33.6683417085427, Blast_Score=98, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17556833, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=201, Percent_Identity=30.3482587064677, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920712, Length=160, Percent_Identity=35.625, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_CHLPN (Q9Z7D1)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B72036
- PIR:   E86587
- RefSeq:   NP_224970.1
- RefSeq:   NP_300832.1
- RefSeq:   NP_445634.1
- RefSeq:   NP_877075.1
- ProteinModelPortal:   Q9Z7D1
- SMR:   Q9Z7D1
- GeneID:   1467482
- GeneID:   895062
- GeneID:   919544
- GeneID:   963585
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP1097
- KEGG:   cpj:CPj0775
- KEGG:   cpn:CPn0775
- KEGG:   cpt:CpB0802
- TIGR:   CP_1097
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- PhylomeDB:   Q9Z7D1
- ProtClustDB:   PRK00120
- BioCyc:   CPNE115711:CP_1097-MONOMER
- BioCyc:   CPNE115713:CPN0775-MONOMER
- BioCyc:   CPNE138677:CPJ0775-MONOMER
- BioCyc:   CPNE182082:CPB0802-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 23136; Mature: 23136

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQEDSITANALTKGIHAAN
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HLGCWVIADDTMLRVPALNGLPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYF
HCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIFVKYDYKQTFAELSEDVKNQV
HEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
SHRAKALQKLAPHLQSLFEKHLLTRD
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQEDSITANALTKGIHAAN
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HLGCWVIADDTMLRVPALNGLPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYF
HCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIFVKYDYKQTFAELSEDVKNQV
HEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
SHRAKALQKLAPHLQSLFEKHLLTRD
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362