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Identifier: 15836294

GI number: 15836294

Start: 857025

End: 857699

Strand: Direct

Name: Not Available

Synonym: CPj0761

Alternate gene names: NA

Gene position: 857025-857699 (Clockwise)

Preceding gene: 15836293

Following gene: 15836300

Centisome position: 69.87

GC content: 38.81

Gene sequence:

>675_bases
ATGACATCCTGGATAGAATTACTTGATAAGCAAATTGAAGATCAACATATGTTAAAGCACGAATTTTATCAGCGTTGGTC
TGAAGGAAAGTTAGAAAAACAACAACTTCAAGCTTATGCCAAAGATTACTATTTACATATTAAAGCATTTCCTTGTTACC
TTTCAGCGCTGCATGCTCGCTGTGATGACTTGCAGATTCGTAGACAAATTCTTGAGAATCTCATGGATGAAGAAGCTGGA
AATCCTAATCACATAGATTTATGGAGACAGTTTGCTTTATCTCTTGGAGTTTCTGAAGAGGAGCTTGCCAATCATGAATT
CAGTCAGGCTGCTCAAGATATGGTAGCGACATTTCGCCGCTTATGCGACATGCCACAACTTGCCGTGGGTTTAGGCGCTC
TCTATACTTATGAGATTCAGATTCCTCAAGTCTGTGTAGAGAAAATCCGTGGTTTGAAAGAATATTTTGGAGTTTCTGCT
CGAGGCTATGCATACTTTACTGTACATCAAGAAGCTGATATTAAACATGCCAGCGAAGAGAAAGAAATGCTACAAACTTT
GGTAGGCAGAGAGAATCCTGATGCTGTTTTGCAAGGATCACAAGAAGTTTTAGATACTCTATGGAACTTTTTGAGCTCTT
TTATTAATTCAACGGAGCCTTGTTCTTGTAAGTAG

Upstream 100 bases:

>100_bases
AGATATGAGCACTTTAGCAATCGCTGAGGATGAAGATTTATATGGTCCTCTGCTACAATCTATGGCATGGGAAACTCCCG
CACCAACCTCCTGAGGTATT

Downstream 100 bases:

>100_bases
TATCTTGGCAGGTCTAGAATTTTTGGATCTTATTAGCTTAAAAAATAGGATCATGCATCTGTAAACAGAATCCCCCCTCC
TAAAGTATTAGAAGGGGGGA

Product: hypothetical protein

Products: NA

Alternate protein names: Chlamydia protein associating with death domains; CADD

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTSWIELLDKQIEDQHMLKHEFYQRWSEGKLEKQQLQAYAKDYYLHIKAFPCYLSALHARCDDLQIRRQILENLMDEEAG
NPNHIDLWRQFALSLGVSEEELANHEFSQAAQDMVATFRRLCDMPQLAVGLGALYTYEIQIPQVCVEKIRGLKEYFGVSA
RGYAYFTVHQEADIKHASEEKEMLQTLVGRENPDAVLQGSQEVLDTLWNFLSSFINSTEPCSCK

Sequences:

>Translated_224_residues
MTSWIELLDKQIEDQHMLKHEFYQRWSEGKLEKQQLQAYAKDYYLHIKAFPCYLSALHARCDDLQIRRQILENLMDEEAG
NPNHIDLWRQFALSLGVSEEELANHEFSQAAQDMVATFRRLCDMPQLAVGLGALYTYEIQIPQVCVEKIRGLKEYFGVSA
RGYAYFTVHQEADIKHASEEKEMLQTLVGRENPDAVLQGSQEVLDTLWNFLSSFINSTEPCSCK
>Mature_223_residues
TSWIELLDKQIEDQHMLKHEFYQRWSEGKLEKQQLQAYAKDYYLHIKAFPCYLSALHARCDDLQIRRQILENLMDEEAGN
PNHIDLWRQFALSLGVSEEELANHEFSQAAQDMVATFRRLCDMPQLAVGLGALYTYEIQIPQVCVEKIRGLKEYFGVSAR
GYAYFTVHQEADIKHASEEKEMLQTLVGRENPDAVLQGSQEVLDTLWNFLSSFINSTEPCSCK

Specific function: Chlamydia specific toxin inducing apoptosis in mammalian cell lines

COG id: COG5424

COG function: function code H; Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C

Gene ontology:

Cell location: Secreted. Note=Secreted into the host cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pqqC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PQQCL_CHLPN (Q9Z7E5)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B72040
- PIR:   G86585
- RefSeq:   NP_224956.1
- RefSeq:   NP_300818.1
- RefSeq:   NP_445648.1
- RefSeq:   NP_877061.1
- ProteinModelPortal:   Q9Z7E5
- SMR:   Q9Z7E5
- GeneID:   1467468
- GeneID:   894950
- GeneID:   919532
- GeneID:   963600
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP1111
- KEGG:   cpj:CPj0761
- KEGG:   cpn:CPn0761
- KEGG:   cpt:CpB0789
- TIGR:   CP_1111
- HOGENOM:   HBG293036
- OMA:   KGKSANK
- ProtClustDB:   CLSK871484
- BioCyc:   CPNE115711:CP_1111-MONOMER
- BioCyc:   CPNE115713:CPN0761-MONOMER
- BioCyc:   CPNE138677:CPJ0761-MONOMER
- BioCyc:   CPNE182082:CPB0789-MONOMER
- GO:   GO:0009405
- InterPro:   IPR016084
- InterPro:   IPR004305
- Gene3D:   G3DSA:1.20.910.10

Pfam domain/function: PF03070 TENA_THI-4; SSF48613 Heme_oxygenase

EC number: NA

Molecular weight: Translated: 25972; Mature: 25840

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSWIELLDKQIEDQHMLKHEFYQRWSEGKLEKQQLQAYAKDYYLHIKAFPCYLSALHAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CDDLQIRRQILENLMDEEAGNPNHIDLWRQFALSLGVSEEELANHEFSQAAQDMVATFRR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LCDMPQLAVGLGALYTYEIQIPQVCVEKIRGLKEYFGVSARGYAYFTVHQEADIKHASEE
HHCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHH
KEMLQTLVGRENPDAVLQGSQEVLDTLWNFLSSFINSTEPCSCK
HHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSWIELLDKQIEDQHMLKHEFYQRWSEGKLEKQQLQAYAKDYYLHIKAFPCYLSALHAR
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CDDLQIRRQILENLMDEEAGNPNHIDLWRQFALSLGVSEEELANHEFSQAAQDMVATFRR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LCDMPQLAVGLGALYTYEIQIPQVCVEKIRGLKEYFGVSARGYAYFTVHQEADIKHASEE
HHCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHH
KEMLQTLVGRENPDAVLQGSQEVLDTLWNFLSSFINSTEPCSCK
HHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362