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The map label for this gene is kpsF

Identifier: 15836057

GI number: 15836057

Start: 607027

End: 608016

Strand: Reverse

Name: kpsF

Synonym: CPj0526

Alternate gene names: 15836057

Gene position: 608016-607027 (Counterclockwise)

Preceding gene: 15836058

Following gene: 15836052

Centisome position: 49.57

GC content: 41.11

Gene sequence:

>990_bases
ATGCCTTCCCCGATGATTTCTACTGACGTATGCCAAGACATTCTAGGTAAGCAAAAAGAAGCTGTAGATTTTTTTTTCCA
AGCCTTTCAACCCAAAGAGGCAATGCAATTAGCAGAAAAAATACTCGGTCATTCGGGATGGGTATTTTTTTCTGGTGTAG
GGAAAAGTGGATGTGTAGCACGAAAATTAGTGGCTACACTCCAATCTTTAAGTGAACGTGCTCTGTTCTTTTCTCCTGTG
GATCTTCTGCACGGGGATCTTGGTCTTGTGAGTCCTGGAGACATTGTATGTTTATTTTCTAAAAGTGGTGAAACCCAAGA
GTTACTAGATACGGTTCCTCATCTAAAGAGTCGAAGGGCGATTCTTGTCGCGATTACTTCCATGCCTTATTCTAATTTAG
CGGCTCTCTCGGACTTAGTCGTTATTTTACCCTCTGTTGCTGAATTAGATCCTTTTAATTTAATCCCTACAAATTCTACG
ACATGCCAAATGATCTTTGGAGATTTTTTAGCTATGCTCCTTTTTCATAGTCGTGGTGTTTCTTTATCTACGTACGGCAA
AAACCATCCTAGTGGGCAGGTTGGGATGAAGGCTAATGGTAAGGTTAAAGATTTTATGTTCCCAAAGACAGAGGTACCTT
TCTGTCATCTTGGAGATAAAGTGAGTTTTTCTTTAGAGGTCTTTTCTGCTTACGGTTGTGGTTGTGTTTGTATAGTAGAT
CCTCAATTCCGACTTATGGGAATTTTTACAGACGGAGATTTACGGCGTTCTTTAGCTTCCTATGGGGGGGAGGTGCTTTC
GTTATCTTTGGAGAAGGTGATGACGGCAAATCCTCGATGTATTACTGAAGATTCGGATATTGCCATTGCTTTGCAACTTA
TGGAATCTAGTAGTCCTGTAGCTGTTCTTCCTGTTTTAGATAACGAGGAGAACCGACATGTGACTGGCTTGTTGCATATG
CACACTTTAGCCAAAGCTGGTCTACTTTGA

Upstream 100 bases:

>100_bases
TATTGGATGGTATTTACGGCAGTGAGTTTTTAACCTCATTGAAAAATCGTTTGGAGTCTGTTACGATGGGCTAAAGTGTA
GCCAATCCAAAGAGAACCGA

Downstream 100 bases:

>100_bases
GAATATGAGAAAAATATCGGAAGAGAGGGTAAGCTGGATTCTGTCTATAAGATAGCTCTTGCGAACTATCCTAAGGGCAA
CCATTCATCTAGGGGAGCTA

Product: GutQ/KpsF family sugar-P isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPSPMISTDVCQDILGKQKEAVDFFFQAFQPKEAMQLAEKILGHSGWVFFSGVGKSGCVARKLVATLQSLSERALFFSPV
DLLHGDLGLVSPGDIVCLFSKSGETQELLDTVPHLKSRRAILVAITSMPYSNLAALSDLVVILPSVAELDPFNLIPTNST
TCQMIFGDFLAMLLFHSRGVSLSTYGKNHPSGQVGMKANGKVKDFMFPKTEVPFCHLGDKVSFSLEVFSAYGCGCVCIVD
PQFRLMGIFTDGDLRRSLASYGGEVLSLSLEKVMTANPRCITEDSDIAIALQLMESSSPVAVLPVLDNEENRHVTGLLHM
HTLAKAGLL

Sequences:

>Translated_329_residues
MPSPMISTDVCQDILGKQKEAVDFFFQAFQPKEAMQLAEKILGHSGWVFFSGVGKSGCVARKLVATLQSLSERALFFSPV
DLLHGDLGLVSPGDIVCLFSKSGETQELLDTVPHLKSRRAILVAITSMPYSNLAALSDLVVILPSVAELDPFNLIPTNST
TCQMIFGDFLAMLLFHSRGVSLSTYGKNHPSGQVGMKANGKVKDFMFPKTEVPFCHLGDKVSFSLEVFSAYGCGCVCIVD
PQFRLMGIFTDGDLRRSLASYGGEVLSLSLEKVMTANPRCITEDSDIAIALQLMESSSPVAVLPVLDNEENRHVTGLLHM
HTLAKAGLL
>Mature_328_residues
PSPMISTDVCQDILGKQKEAVDFFFQAFQPKEAMQLAEKILGHSGWVFFSGVGKSGCVARKLVATLQSLSERALFFSPVD
LLHGDLGLVSPGDIVCLFSKSGETQELLDTVPHLKSRRAILVAITSMPYSNLAALSDLVVILPSVAELDPFNLIPTNSTT
CQMIFGDFLAMLLFHSRGVSLSTYGKNHPSGQVGMKANGKVKDFMFPKTEVPFCHLGDKVSFSLEVFSAYGCGCVCIVDP
QFRLMGIFTDGDLRRSLASYGGEVLSLSLEKVMTANPRCITEDSDIAIALQLMESSSPVAVLPVLDNEENRHVTGLLHMH
TLAKAGLL

Specific function: Unknown

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1789588, Length=291, Percent_Identity=35.3951890034364, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082151, Length=295, Percent_Identity=32.8813559322034, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y526_CHLPN (Q9Z826)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B86556
- PIR:   E72068
- RefSeq:   NP_224722.1
- RefSeq:   NP_300581.1
- RefSeq:   NP_444777.1
- RefSeq:   NP_876819.1
- ProteinModelPortal:   Q9Z826
- GeneID:   1467226
- GeneID:   895418
- GeneID:   919278
- GeneID:   962944
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0226
- KEGG:   cpj:CPj0526
- KEGG:   cpn:CPn0526
- KEGG:   cpt:CpB0547
- TIGR:   CP_0226
- HOGENOM:   HBG754974
- OMA:   MLAMGDA
- PhylomeDB:   Q9Z826
- ProtClustDB:   CLSK871357
- BioCyc:   CPNE115711:CP_0226-MONOMER
- BioCyc:   CPNE115713:CPN0526-MONOMER
- BioCyc:   CPNE138677:CPJ0526-MONOMER
- BioCyc:   CPNE182082:CPB0547-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR004800
- InterPro:   IPR001347
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00116
- TIGRFAMs:   TIGR00393

Pfam domain/function: PF00571 CBS; PF01380 SIS

EC number: NA

Molecular weight: Translated: 35651; Mature: 35520

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS51371 CBS; PS51464 SIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPMISTDVCQDILGKQKEAVDFFFQAFQPKEAMQLAEKILGHSGWVFFSGVGKSGCVA
CCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHH
RKLVATLQSLSERALFFSPVDLLHGDLGLVSPGDIVCLFSKSGETQELLDTVPHLKSRRA
HHHHHHHHHHHHHHEEECCHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCE
ILVAITSMPYSNLAALSDLVVILPSVAELDPFNLIPTNSTTCQMIFGDFLAMLLFHSRGV
EEEEEECCCCHHHHHHHHHHHHHCCHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCC
SLSTYGKNHPSGQVGMKANGKVKDFMFPKTEVPFCHLGDKVSFSLEVFSAYGCGCVCIVD
EEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCEEEEEEEEECCCCCEEEEEC
PQFRLMGIFTDGDLRRSLASYGGEVLSLSLEKVMTANPRCITEDSDIAIALQLMESSSPV
CCEEEEEEEECHHHHHHHHHCCCCEEEEEHHHHHCCCCCEECCCCCEEEEEEEECCCCCE
AVLPVLDNEENRHVTGLLHMHTLAKAGLL
EEEEEECCCCCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSPMISTDVCQDILGKQKEAVDFFFQAFQPKEAMQLAEKILGHSGWVFFSGVGKSGCVA
CCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHH
RKLVATLQSLSERALFFSPVDLLHGDLGLVSPGDIVCLFSKSGETQELLDTVPHLKSRRA
HHHHHHHHHHHHHHEEECCHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCE
ILVAITSMPYSNLAALSDLVVILPSVAELDPFNLIPTNSTTCQMIFGDFLAMLLFHSRGV
EEEEEECCCCHHHHHHHHHHHHHCCHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCC
SLSTYGKNHPSGQVGMKANGKVKDFMFPKTEVPFCHLGDKVSFSLEVFSAYGCGCVCIVD
EEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCEEEEEEEEECCCCCEEEEEC
PQFRLMGIFTDGDLRRSLASYGGEVLSLSLEKVMTANPRCITEDSDIAIALQLMESSSPV
CCEEEEEEEECHHHHHHHHHCCCCEEEEEHHHHHCCCCCEECCCCCEEEEEEEECCCCCE
AVLPVLDNEENRHVTGLLHMHTLAKAGLL
EEEEEECCCCCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362