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The map label for this gene is accA

Identifier: 15835947

GI number: 15835947

Start: 458878

End: 459852

Strand: Reverse

Name: accA

Synonym: CPj0414

Alternate gene names: 15835947

Gene position: 459852-458878 (Counterclockwise)

Preceding gene: 15835948

Following gene: 15835946

Centisome position: 37.49

GC content: 42.46

Gene sequence:

>975_bases
ATGGAACTTCTTCCACACGAAAAACAAGTAGTTGAATATGAAAAGGCTATAGCCGAATTTAAAGAAAAAAATAAGAAAAA
TTCTCTCTTATCTTCTTCAGAGATTCAGAAATTGGAAAAGCGTTTAGATAAATTAAAAGAAAAGATCTATTCGGATTTGA
CTCCTTGGGAGCGTGTACAAATATGTCGCCACCCTTCGCGTCCCCGTACTGTCAACTATATTGAAGGGATGTGTGAGGAG
TTTGTCGAGCTTTGTGGAGATCGCACCTTCCGAGATGATCCCGCAGTTGTTGGTGGCTTTGTAAAAATCCAGGGTCAGCG
TTTTGTCCTTATTGGCCAAGAAAAGGGATGCGATACAGCGTCACGCCTTCATAGGAACTTCGGTATGTTATGTCCCGAGG
GTTTCAGAAAAGCCCTTCGCTTAGGAAAACTCGCTGAAAAGTTTGGCTTGCCTGTGGTCTTTCTTGTCGATACCCCAGGA
GCATATCCTGGATTGACTGCTGAAGAGAGAGGACAAGGATGGGCAATTGCCAAAAATCTTTTTGAGCTCTCAAGACTTGC
CACTCCCGTGATTATTGTCGTTATCGGTGAGGGATGTTCAGGTGGAGCTTTGGGCATGGCTGTAGGTGATTCTGTAGCTA
TGTTAGAGCATTCCTATTATTCTGTAATTTCCCCAGAAGGATGCGCCTCCATTCTTTGGAAAGATCCTAAGAAAAATAGC
GAAGCAGCTTCCATGTTGAAAATGCATGGAGAAAACTTAAAACAATTTGGCATTATCGATACTGTTATCAAAGAGCCCAT
TGGGGGAGCTCACCACGATCCTGCATTGGTATATAGCAATGTTCGAGAGTTTATCATCCAAGAGTGGTTACGATTAAAAG
ATCTAGCTATAGAAGAGCTGTTGGAGAAACGGTACGAAAAATTTCGCTCTATAGGTCTTTATGAAACTACTTCTGAAAGC
GGTCCTGAGGCATAA

Upstream 100 bases:

>100_bases
GAAGATTCTTTACGAAGATGAATTAATTTTGGGTCTGTAATTGTGTTTAAGAATTGTTTGTATTAAAATGATTCTTTTTA
TACGAGGAGAGCACATTCTA

Downstream 100 bases:

>100_bases
AAATCATCTCGTTATATTAGGCTGTTCTCTACTCGCAATTTTAGGACTTACCTTTTCATCTCAGATGGAGATTTTTTCTT
TAGGGATGATTGCTAAAACA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MELLPHEKQVVEYEKAIAEFKEKNKKNSLLSSSEIQKLEKRLDKLKEKIYSDLTPWERVQICRHPSRPRTVNYIEGMCEE
FVELCGDRTFRDDPAVVGGFVKIQGQRFVLIGQEKGCDTASRLHRNFGMLCPEGFRKALRLGKLAEKFGLPVVFLVDTPG
AYPGLTAEERGQGWAIAKNLFELSRLATPVIIVVIGEGCSGGALGMAVGDSVAMLEHSYYSVISPEGCASILWKDPKKNS
EAASMLKMHGENLKQFGIIDTVIKEPIGGAHHDPALVYSNVREFIIQEWLRLKDLAIEELLEKRYEKFRSIGLYETTSES
GPEA

Sequences:

>Translated_324_residues
MELLPHEKQVVEYEKAIAEFKEKNKKNSLLSSSEIQKLEKRLDKLKEKIYSDLTPWERVQICRHPSRPRTVNYIEGMCEE
FVELCGDRTFRDDPAVVGGFVKIQGQRFVLIGQEKGCDTASRLHRNFGMLCPEGFRKALRLGKLAEKFGLPVVFLVDTPG
AYPGLTAEERGQGWAIAKNLFELSRLATPVIIVVIGEGCSGGALGMAVGDSVAMLEHSYYSVISPEGCASILWKDPKKNS
EAASMLKMHGENLKQFGIIDTVIKEPIGGAHHDPALVYSNVREFIIQEWLRLKDLAIEELLEKRYEKFRSIGLYETTSES
GPEA
>Mature_324_residues
MELLPHEKQVVEYEKAIAEFKEKNKKNSLLSSSEIQKLEKRLDKLKEKIYSDLTPWERVQICRHPSRPRTVNYIEGMCEE
FVELCGDRTFRDDPAVVGGFVKIQGQRFVLIGQEKGCDTASRLHRNFGMLCPEGFRKALRLGKLAEKFGLPVVFLVDTPG
AYPGLTAEERGQGWAIAKNLFELSRLATPVIIVVIGEGCSGGALGMAVGDSVAMLEHSYYSVISPEGCASILWKDPKKNS
EAASMLKMHGENLKQFGIIDTVIKEPIGGAHHDPALVYSNVREFIIQEWLRLKDLAIEELLEKRYEKFRSIGLYETTSES
GPEA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=315, Percent_Identity=44.1269841269841, Blast_Score=292, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_CHLPN (Q9Z8C9)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D86542
- PIR:   E72083
- RefSeq:   NP_224614.1
- RefSeq:   NP_300471.1
- RefSeq:   NP_444889.1
- RefSeq:   NP_876704.1
- ProteinModelPortal:   Q9Z8C9
- SMR:   Q9Z8C9
- PHCI-2DPAGE:   Q9Z8C9
- GeneID:   1467111
- GeneID:   895203
- GeneID:   919155
- GeneID:   963229
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0340
- KEGG:   cpj:CPj0414
- KEGG:   cpn:CPn0414
- KEGG:   cpt:CpB0430
- TIGR:   CP_0340
- HOGENOM:   HBG286557
- OMA:   GSPEPWG
- PhylomeDB:   Q9Z8C9
- ProtClustDB:   PRK05724
- BioCyc:   CPNE115711:CP_0340-MONOMER
- BioCyc:   CPNE115713:CPN0414-MONOMER
- BioCyc:   CPNE138677:CPJ0414-MONOMER
- BioCyc:   CPNE182082:CPB0430-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36347; Mature: 36347

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLPHEKQVVEYEKAIAEFKEKNKKNSLLSSSEIQKLEKRLDKLKEKIYSDLTPWERVQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ICRHPSRPRTVNYIEGMCEEFVELCGDRTFRDDPAVVGGFVKIQGQRFVLIGQEKGCDTA
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEECCCEEEEEECCCCCCHH
SRLHRNFGMLCPEGFRKALRLGKLAEKFGLPVVFLVDTPGAYPGLTAEERGQGWAIAKNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCHHHHHHH
FELSRLATPVIIVVIGEGCSGGALGMAVGDSVAMLEHSYYSVISPEGCASILWKDPKKNS
HHHHHHCCCEEEEEEECCCCCCEEHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCH
EAASMLKMHGENLKQFGIIDTVIKEPIGGAHHDPALVYSNVREFIIQEWLRLKDLAIEEL
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKRYEKFRSIGLYETTSESGPEA
HHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MELLPHEKQVVEYEKAIAEFKEKNKKNSLLSSSEIQKLEKRLDKLKEKIYSDLTPWERVQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ICRHPSRPRTVNYIEGMCEEFVELCGDRTFRDDPAVVGGFVKIQGQRFVLIGQEKGCDTA
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEECCCEEEEEECCCCCCHH
SRLHRNFGMLCPEGFRKALRLGKLAEKFGLPVVFLVDTPGAYPGLTAEERGQGWAIAKNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCHHHHHHH
FELSRLATPVIIVVIGEGCSGGALGMAVGDSVAMLEHSYYSVISPEGCASILWKDPKKNS
HHHHHHCCCEEEEEEECCCCCCEEHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCH
EAASMLKMHGENLKQFGIIDTVIKEPIGGAHHDPALVYSNVREFIIQEWLRLKDLAIEEL
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKRYEKFRSIGLYETTSESGPEA
HHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362