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The map label for this gene is yaeL

Identifier: 15835877

GI number: 15835877

Start: 385178

End: 387043

Strand: Reverse

Name: yaeL

Synonym: CPj0343

Alternate gene names: 15835877

Gene position: 387043-385178 (Counterclockwise)

Preceding gene: 15835878

Following gene: 15835872

Centisome position: 31.56

GC content: 40.3

Gene sequence:

>1866_bases
ATGACAATAATCTATTTTATTCTAGCAGCCCTAGCTTTAGGGATTTTAGTGTTAATTCATGAACTTGGTCATCTGGTAGT
AGCAAAAGCTGTAGGAATGGCTGTAGAGAGTTTTAGCATAGGCTTTGGTCCTGCTTTATTTAAAAAGCGTATAGGCGGCA
TAGAATATCGCATTGGATGCATTCCTTTTGGAGGCTATGTTCGTATCAGAGGTATGGAACGTACCAAAGAAAAAGGGGAG
AAGGGGAAGATAGACTCTGTCTATGATATTCCTCAGGGATTTTTTAGTAAGTCTCCTTGGAAACGCATTCTGGTTCTTGT
TGCTGGTCCTCTTGCCAATATTTTATTAGCTGTCTTGGCTTTCAGCATTCTTTACATGAATGGGGGAAGAAGTAAAAATT
ATAGCGACTGTTCTAAAGTGGTAGGTTGGGTCCATCCTGTTTTACAGGCAGAAGGATTGCTCCCTGGAGACGAGATTCTT
ACGTGTAATGGTAAGCCTTATGTGGGAGATAAGGACATGCTAACAACCTCTTTATTAGAGGGGCATCTCAATCTAGAAAT
CAAACGTCCTGGCTATTTGACAGTTCCTAGCAAAGAGTTCGCTATTGATGTTGAGTTTGATCCCACAAAATTCGGGGTTC
CCTGTTCTGGAGCGAGTTATCTTTTGTATGGCAACCAGGTGCCCCTAACGAAGAACTCTCCTATGGAGAATTCAGAGCTA
CGTCCGAATGATCGTTTCGTTTGGATGGATGGCACACTTCTTTTCTCAATGGCTCAGATATCTCAGATACTCAATGAGTC
TTATGCTTTTGTGAAAGTAGCACGGAATGACAAAATCTTCTTTTCTCGTCAACCTAGGGTATTGGCTTCCGTTTTACATT
ACACTCCCTACCTTCGTAATGAGCTTATAGATACGCAGTATGAGGCTGGACTTAAAGGCAAGTGGTCTTCGTTATATACA
TTGCCTTATGTAATCAATAGTTATGGATACATAGAAGGTGAACTTACTGCTATAGATCCAGAGTCTCCTTTGCCACAACC
TCAAGAGAGGCTACAGCTTGGGGATCGCATTCTAGCTATTGATGGAACTCCTGTTTCTGGAAGTGTAGATATTTTACGTC
TTGTTCAGAACCATCGGGTCTCTATTATTGTTCAGCAGATGAGTCCGCAAGAACTTGAAGAGGTGAATTCTCGAGATGCT
GATAAGCGGTTTATCGCCTCTTATCATTCCGAAGATCTGTTACAAATTTTGAACCATTTAGGAGAGTCTCACCCAGTAGA
AGTCGCGGGTCCTTATCGTCTTCTTGACCCTGTTCAGCCTCGTCCTTGGATTGATGTTTATTCTTCGGAGAGTTTGGATA
AACAGTTGGAAGTAGCTAAGAAGATTAAGAACAAGGATAAACAAAGATACTATTTGGAGCGTCTTGATGCTGAGAAGCAA
AAACCATCTTTAGGGATTTCTTTGAAAGATCTTAAGGTGAGGTATAATCCTTCACCTGTGGTTATGTTATCAAATATTAC
TAAGGAAAGTTTGATCACCTTGAAAGCTTTAGTTACTGGACATCTGAGTCCACAATGGCTTTCAGGACCTGTGGGTATTG
TGCAGGTTTTACATACAGGATGGTCGGTAGGGTTTTCTGAAGTGCTCTTTTGGATCGGTCTAATTAGTATGAATTTGGCT
GTCTTGAATTTGCTTCCTATTCCTGTTTTGGATGGAGGTTATATCCTTCTATGTTTGTGGGAGATAGTCACAAGAAGACG
TTTGAATATGAAGATTGTGGAAAGGATTTTGGATCCGTTCACTTTTTTATTGATCATCTTCTTTATTTTTCTAACTTTTC
AGGATTTATTTCGTTTTTTTGGTTAA

Upstream 100 bases:

>100_bases
GGAATGTCATAAGGTTTATGCCTGCCACTCTTTAGAAGATATTTTAGAAGTAGATGGTGAGGCTAGAGCTCTTGCTCAAG
AAATATAATCGAGTAGGTAT

Downstream 100 bases:

>100_bases
GGCTCCATTTTTTTGGAAATCCGTAAAGGTTGTAAGGACGAGAACCAAAGCAGTGTATAACGTAGATGTCTTGGTTAGGG
TAAGGCTTAAGTCTTGAGTT

Product: metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTIIYFILAALALGILVLIHELGHLVVAKAVGMAVESFSIGFGPALFKKRIGGIEYRIGCIPFGGYVRIRGMERTKEKGE
KGKIDSVYDIPQGFFSKSPWKRILVLVAGPLANILLAVLAFSILYMNGGRSKNYSDCSKVVGWVHPVLQAEGLLPGDEIL
TCNGKPYVGDKDMLTTSLLEGHLNLEIKRPGYLTVPSKEFAIDVEFDPTKFGVPCSGASYLLYGNQVPLTKNSPMENSEL
RPNDRFVWMDGTLLFSMAQISQILNESYAFVKVARNDKIFFSRQPRVLASVLHYTPYLRNELIDTQYEAGLKGKWSSLYT
LPYVINSYGYIEGELTAIDPESPLPQPQERLQLGDRILAIDGTPVSGSVDILRLVQNHRVSIIVQQMSPQELEEVNSRDA
DKRFIASYHSEDLLQILNHLGESHPVEVAGPYRLLDPVQPRPWIDVYSSESLDKQLEVAKKIKNKDKQRYYLERLDAEKQ
KPSLGISLKDLKVRYNPSPVVMLSNITKESLITLKALVTGHLSPQWLSGPVGIVQVLHTGWSVGFSEVLFWIGLISMNLA
VLNLLPIPVLDGGYILLCLWEIVTRRRLNMKIVERILDPFTFLLIIFFIFLTFQDLFRFFG

Sequences:

>Translated_621_residues
MTIIYFILAALALGILVLIHELGHLVVAKAVGMAVESFSIGFGPALFKKRIGGIEYRIGCIPFGGYVRIRGMERTKEKGE
KGKIDSVYDIPQGFFSKSPWKRILVLVAGPLANILLAVLAFSILYMNGGRSKNYSDCSKVVGWVHPVLQAEGLLPGDEIL
TCNGKPYVGDKDMLTTSLLEGHLNLEIKRPGYLTVPSKEFAIDVEFDPTKFGVPCSGASYLLYGNQVPLTKNSPMENSEL
RPNDRFVWMDGTLLFSMAQISQILNESYAFVKVARNDKIFFSRQPRVLASVLHYTPYLRNELIDTQYEAGLKGKWSSLYT
LPYVINSYGYIEGELTAIDPESPLPQPQERLQLGDRILAIDGTPVSGSVDILRLVQNHRVSIIVQQMSPQELEEVNSRDA
DKRFIASYHSEDLLQILNHLGESHPVEVAGPYRLLDPVQPRPWIDVYSSESLDKQLEVAKKIKNKDKQRYYLERLDAEKQ
KPSLGISLKDLKVRYNPSPVVMLSNITKESLITLKALVTGHLSPQWLSGPVGIVQVLHTGWSVGFSEVLFWIGLISMNLA
VLNLLPIPVLDGGYILLCLWEIVTRRRLNMKIVERILDPFTFLLIIFFIFLTFQDLFRFFG
>Mature_620_residues
TIIYFILAALALGILVLIHELGHLVVAKAVGMAVESFSIGFGPALFKKRIGGIEYRIGCIPFGGYVRIRGMERTKEKGEK
GKIDSVYDIPQGFFSKSPWKRILVLVAGPLANILLAVLAFSILYMNGGRSKNYSDCSKVVGWVHPVLQAEGLLPGDEILT
CNGKPYVGDKDMLTTSLLEGHLNLEIKRPGYLTVPSKEFAIDVEFDPTKFGVPCSGASYLLYGNQVPLTKNSPMENSELR
PNDRFVWMDGTLLFSMAQISQILNESYAFVKVARNDKIFFSRQPRVLASVLHYTPYLRNELIDTQYEAGLKGKWSSLYTL
PYVINSYGYIEGELTAIDPESPLPQPQERLQLGDRILAIDGTPVSGSVDILRLVQNHRVSIIVQQMSPQELEEVNSRDAD
KRFIASYHSEDLLQILNHLGESHPVEVAGPYRLLDPVQPRPWIDVYSSESLDKQLEVAKKIKNKDKQRYYLERLDAEKQK
PSLGISLKDLKVRYNPSPVVMLSNITKESLITLKALVTGHLSPQWLSGPVGIVQVLHTGWSVGFSEVLFWIGLISMNLAV
LNLLPIPVLDGGYILLCLWEIVTRRRLNMKIVERILDPFTFLLIIFFIFLTFQDLFRFFG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M50B family [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=280, Percent_Identity=27.8571428571429, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 69837; Mature: 69706

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIYFILAALALGILVLIHELGHLVVAKAVGMAVESFSIGFGPALFKKRIGGIEYRIGC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEE
IPFGGYVRIRGMERTKEKGEKGKIDSVYDIPQGFFSKSPWKRILVLVAGPLANILLAVLA
EECCCEEEEECCHHHHHCCCCCCCCCHHHCCHHHCCCCCHHHEEHHHCCHHHHHHHHHHH
FSILYMNGGRSKNYSDCSKVVGWVHPVLQAEGLLPGDEILTCNGKPYVGDKDMLTTSLLE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHC
GHLNLEIKRPGYLTVPSKEFAIDVEFDPTKFGVPCSGASYLLYGNQVPLTKNSPMENSEL
CCEEEEEECCCEEEECCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
RPNDRFVWMDGTLLFSMAQISQILNESYAFVKVARNDKIFFSRQPRVLASVLHYTPYLRN
CCCCCEEEECHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCHHHHHHHHHCHHHHH
ELIDTQYEAGLKGKWSSLYTLPYVINSYGYIEGELTAIDPESPLPQPQERLQLGDRILAI
HHHCHHHHCCCCCCCCHHEEHHHHHCCCCEEECEEEEECCCCCCCCHHHHHHHCCEEEEE
DGTPVSGSVDILRLVQNHRVSIIVQQMSPQELEEVNSRDADKRFIASYHSEDLLQILNHL
CCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHC
GESHPVEVAGPYRLLDPVQPRPWIDVYSSESLDKQLEVAKKIKNKDKQRYYLERLDAEKQ
CCCCCEEECCCCHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHC
KPSLGISLKDLKVRYNPSPVVMLSNITKESLITLKALVTGHLSPQWLSGPVGIVQVLHTG
CCCCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCC
WSVGFSEVLFWIGLISMNLAVLNLLPIPVLDGGYILLCLWEIVTRRRLNMKIVERILDPF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
TFLLIIFFIFLTFQDLFRFFG
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIIYFILAALALGILVLIHELGHLVVAKAVGMAVESFSIGFGPALFKKRIGGIEYRIGC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEE
IPFGGYVRIRGMERTKEKGEKGKIDSVYDIPQGFFSKSPWKRILVLVAGPLANILLAVLA
EECCCEEEEECCHHHHHCCCCCCCCCHHHCCHHHCCCCCHHHEEHHHCCHHHHHHHHHHH
FSILYMNGGRSKNYSDCSKVVGWVHPVLQAEGLLPGDEILTCNGKPYVGDKDMLTTSLLE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHC
GHLNLEIKRPGYLTVPSKEFAIDVEFDPTKFGVPCSGASYLLYGNQVPLTKNSPMENSEL
CCEEEEEECCCEEEECCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
RPNDRFVWMDGTLLFSMAQISQILNESYAFVKVARNDKIFFSRQPRVLASVLHYTPYLRN
CCCCCEEEECHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCHHHHHHHHHCHHHHH
ELIDTQYEAGLKGKWSSLYTLPYVINSYGYIEGELTAIDPESPLPQPQERLQLGDRILAI
HHHCHHHHCCCCCCCCHHEEHHHHHCCCCEEECEEEEECCCCCCCCHHHHHHHCCEEEEE
DGTPVSGSVDILRLVQNHRVSIIVQQMSPQELEEVNSRDADKRFIASYHSEDLLQILNHL
CCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHC
GESHPVEVAGPYRLLDPVQPRPWIDVYSSESLDKQLEVAKKIKNKDKQRYYLERLDAEKQ
CCCCCEEECCCCHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHC
KPSLGISLKDLKVRYNPSPVVMLSNITKESLITLKALVTGHLSPQWLSGPVGIVQVLHTG
CCCCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCC
WSVGFSEVLFWIGLISMNLAVLNLLPIPVLDGGYILLCLWEIVTRRRLNMKIVERILDPF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
TFLLIIFFIFLTFQDLFRFFG
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]