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The map label for this gene is acpS

Identifier: 15835848

GI number: 15835848

Start: 354612

End: 354980

Strand: Direct

Name: acpS

Synonym: CPj0313

Alternate gene names: 15835848

Gene position: 354612-354980 (Clockwise)

Preceding gene: 15835847

Following gene: 15835850

Centisome position: 28.91

GC content: 42.28

Gene sequence:

>369_bases
ATGGAAATCATTCATATAGGAACCGATATTATTGAAATTAGCCGCATTCGCGAGGCAATTGCAACTCACGGCAATCGACT
ACTCAATAGAATCTTTACAGAAGCAGAACAGAAATATTGCTTAGAAAAGACCGATCCCATCCCTTCATTTGCAGGTCGCT
TTGCTGGAAAAGAAGCTGTAGCAAAAGCTTTAGGAACTGGCATAGGGAGCGTTGTTGCCTGGAAAGACATCGAAGTCTTT
AAAGTATCTCACGGACCCGAAGTTCTCCTCCCTTCGCATGTCTATGCAAAAATTGGAATTTCTAAAGTCATTCTCTCTAT
AAGCCACTGCAAAGAGTATGCCACAGCAACTGCAATCGCATTAGCCTAA

Upstream 100 bases:

>100_bases
GCTACAGTGGGCTATGCTCTCATTAAAACTGCCATCGCTTACTTCTCAAAATTACAGAATGCCCTAATGGAAAATCCTGA
AGGAAATTAGTGCGAACTCT

Downstream 100 bases:

>100_bases
GAATCTTTCAGCATCTAGTGCTGCTATACAACCACTTCCTGCAGAAGTAACCGCCTGACGATAGTACTTATCCTGAACAT
CTCCAGCAGCAAATACTCCA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MEIIHIGTDIIEISRIREAIATHGNRLLNRIFTEAEQKYCLEKTDPIPSFAGRFAGKEAVAKALGTGIGSVVAWKDIEVF
KVSHGPEVLLPSHVYAKIGISKVILSISHCKEYATATAIALA

Sequences:

>Translated_122_residues
MEIIHIGTDIIEISRIREAIATHGNRLLNRIFTEAEQKYCLEKTDPIPSFAGRFAGKEAVAKALGTGIGSVVAWKDIEVF
KVSHGPEVLLPSHVYAKIGISKVILSISHCKEYATATAIALA
>Mature_122_residues
MEIIHIGTDIIEISRIREAIATHGNRLLNRIFTEAEQKYCLEKTDPIPSFAGRFAGKEAVAKALGTGIGSVVAWKDIEVF
KVSHGPEVLLPSHVYAKIGISKVILSISHCKEYATATAIALA

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=37.3983739837398, Blast_Score=76, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CHLPN (Q9Z8M5)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   A86530
- PIR:   B72093
- RefSeq:   NP_224518.1
- RefSeq:   NP_300372.1
- RefSeq:   NP_444993.1
- RefSeq:   NP_876598.1
- ProteinModelPortal:   Q9Z8M5
- SMR:   Q9Z8M5
- GeneID:   1467005
- GeneID:   894726
- GeneID:   919853
- GeneID:   963712
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0445
- KEGG:   cpn:CPn0313
- KEGG:   cpt:CpB0323
- TIGR:   CP_0445
- HOGENOM:   HBG734479
- OMA:   HIGTDII
- PhylomeDB:   Q9Z8M5
- ProtClustDB:   PRK00070
- BioCyc:   CPNE115711:CP_0445-MONOMER
- BioCyc:   CPNE115713:CPN0313-MONOMER
- BioCyc:   CPNE138677:CPJ0313-MONOMER
- BioCyc:   CPNE182082:CPB0323-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13228; Mature: 13228

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIHIGTDIIEISRIREAIATHGNRLLNRIFTEAEQKYCLEKTDPIPSFAGRFAGKEAV
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHH
AKALGTGIGSVVAWKDIEVFKVSHGPEVLLPSHVYAKIGISKVILSISHCKEYATATAIA
HHHHHCCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LA
CC
>Mature Secondary Structure
MEIIHIGTDIIEISRIREAIATHGNRLLNRIFTEAEQKYCLEKTDPIPSFAGRFAGKEAV
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHH
AKALGTGIGSVVAWKDIEVFKVSHGPEVLLPSHVYAKIGISKVILSISHCKEYATATAIA
HHHHHCCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362