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The map label for this gene is surE

Identifier: 15835797

GI number: 15835797

Start: 294713

End: 295558

Strand: Direct

Name: surE

Synonym: CPj0262

Alternate gene names: 15835797

Gene position: 294713-295558 (Clockwise)

Preceding gene: 15835796

Following gene: 15835798

Centisome position: 24.03

GC content: 40.9

Gene sequence:

>846_bases
TTGGTTCTCATGAATAAAAGATTAAAGATAATTCTAACTAATGATGATGGAATCACAGCTAAAGGAATGAGTTGCCTAGT
CTCTGCTCTATTGGAAGCAAATATTGGTGATATTTATATTGCAGCTCCCCAAGCCGAACAGTCGGGGAAAAGCATGGCAA
TCTCTCTGAACCAAGTAGTCTGCGCCTCTCCGTATGCATACCCGCAACCCGTTAAAGAAGCATGGGCAGTAGGAGGCTCT
CCTACAGATTGCGTTAGACTCGGCCTTAGAACACTTTTTGAATCGGTTTCCCCTGATTTAGTGATTTCAGGAATTAACTG
TGGGAACAACATATGCAAGAATGCTTGGTATTCAGGAACCATAGGCGCTGCAAAACAAGCCTTGGTCGATGGCATTCCAT
CGATGGCACTTTCTCAGGATAACCATATTTCTTTCTTTCAACAAGACAAGGCTCCTGAAATTTTAAAAGCATTAGTGATT
TATCTCTTGTCTCAACCCTTTCCTTGTTTAACTGGGTTAAATATTAACTTTCCTACCAGTCCTGGGGGTTCCTCTTGGGA
AGGTATGCGACTTGTGCCTCCAGGAGATGAATTTTTTTACGAGGAACCTCAATACCTAGGCTCTGTAAACAAAAATCAAT
ATTATGTAGGGAAAATTTCTGGAGTACGGATTGGAGAGCATCCATCAGAAGAACTCGCTTGCATGCTAGAAAACCATATC
AGCGTGTCTCCTATATTTTCACAAAACTCTCCTATCGGCTTAATGACTCTAGAGGAATTTCAAAAGACACAAGAAAATTT
CAATGCATCGCTTTTAAGCTCTGAGCTGACCACTAAAATTTTCTAA

Upstream 100 bases:

>100_bases
TTTGGCAATTCAAGAACATGGGTCATCCAAATCACAAAAAATTTGAGAGACACTTTGTTATTAATTAATTTTTAATATAA
ATAAGGAAGTAAAAGTTTAC

Downstream 100 bases:

>100_bases
AAGCCCCCTAGTCTTTGGTATCAGAGGTCTTTTTTTACAAAAGATCTCTTGTTTAATCGAGATTTAATCACTTAAATTGA
AAGAAAAATAATTGTGATTA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MVLMNKRLKIILTNDDGITAKGMSCLVSALLEANIGDIYIAAPQAEQSGKSMAISLNQVVCASPYAYPQPVKEAWAVGGS
PTDCVRLGLRTLFESVSPDLVISGINCGNNICKNAWYSGTIGAAKQALVDGIPSMALSQDNHISFFQQDKAPEILKALVI
YLLSQPFPCLTGLNINFPTSPGGSSWEGMRLVPPGDEFFYEEPQYLGSVNKNQYYVGKISGVRIGEHPSEELACMLENHI
SVSPIFSQNSPIGLMTLEEFQKTQENFNASLLSSELTTKIF

Sequences:

>Translated_281_residues
MVLMNKRLKIILTNDDGITAKGMSCLVSALLEANIGDIYIAAPQAEQSGKSMAISLNQVVCASPYAYPQPVKEAWAVGGS
PTDCVRLGLRTLFESVSPDLVISGINCGNNICKNAWYSGTIGAAKQALVDGIPSMALSQDNHISFFQQDKAPEILKALVI
YLLSQPFPCLTGLNINFPTSPGGSSWEGMRLVPPGDEFFYEEPQYLGSVNKNQYYVGKISGVRIGEHPSEELACMLENHI
SVSPIFSQNSPIGLMTLEEFQKTQENFNASLLSSELTTKIF
>Mature_281_residues
MVLMNKRLKIILTNDDGITAKGMSCLVSALLEANIGDIYIAAPQAEQSGKSMAISLNQVVCASPYAYPQPVKEAWAVGGS
PTDCVRLGLRTLFESVSPDLVISGINCGNNICKNAWYSGTIGAAKQALVDGIPSMALSQDNHISFFQQDKAPEILKALVI
YLLSQPFPCLTGLNINFPTSPGGSSWEGMRLVPPGDEFFYEEPQYLGSVNKNQYYVGKISGVRIGEHPSEELACMLENHI
SVSPIFSQNSPIGLMTLEEFQKTQENFNASLLSSELTTKIF

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=241, Percent_Identity=30.2904564315353, Blast_Score=100, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_CHLPN (Q9Z8S6)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   F72099
- PIR:   F86523
- RefSeq:   NP_224467.1
- RefSeq:   NP_300321.1
- RefSeq:   NP_445046.1
- RefSeq:   NP_876545.1
- ProteinModelPortal:   Q9Z8S6
- SMR:   Q9Z8S6
- GeneID:   1466952
- GeneID:   894926
- GeneID:   919034
- GeneID:   963782
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0499
- KEGG:   cpn:CPn0262
- KEGG:   cpt:CpB0269
- TIGR:   CP_0499
- HOGENOM:   HBG600532
- OMA:   DCVKMGI
- PhylomeDB:   Q9Z8S6
- ProtClustDB:   PRK00346
- BioCyc:   CPNE115711:CP_0499-MONOMER
- BioCyc:   CPNE115713:CPN0262-MONOMER
- BioCyc:   CPNE138677:CPJ0262-MONOMER
- BioCyc:   CPNE182082:CPB0269-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 30478; Mature: 30478

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLMNKRLKIILTNDDGITAKGMSCLVSALLEANIGDIYIAAPQAEQSGKSMAISLNQVV
CEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCEE
CASPYAYPQPVKEAWAVGGSPTDCVRLGLRTLFESVSPDLVISGINCGNNICKNAWYSGT
ECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCC
IGAAKQALVDGIPSMALSQDNHISFFQQDKAPEILKALVIYLLSQPFPCLTGLNINFPTS
HHHHHHHHHHCCCCHHCCCCCCEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCC
PGGSSWEGMRLVPPGDEFFYEEPQYLGSVNKNQYYVGKISGVRIGEHPSEELACMLENHI
CCCCCCCCCEECCCCHHHCCCCCHHHCCCCCCEEEEEEECCEECCCCCHHHHHHHHHCCC
SVSPIFSQNSPIGLMTLEEFQKTQENFNASLLSSELTTKIF
CCCEEECCCCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MVLMNKRLKIILTNDDGITAKGMSCLVSALLEANIGDIYIAAPQAEQSGKSMAISLNQVV
CEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCEE
CASPYAYPQPVKEAWAVGGSPTDCVRLGLRTLFESVSPDLVISGINCGNNICKNAWYSGT
ECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCC
IGAAKQALVDGIPSMALSQDNHISFFQQDKAPEILKALVIYLLSQPFPCLTGLNINFPTS
HHHHHHHHHHCCCCHHCCCCCCEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCC
PGGSSWEGMRLVPPGDEFFYEEPQYLGSVNKNQYYVGKISGVRIGEHPSEELACMLENHI
CCCCCCCCCEECCCCHHHCCCCCHHHCCCCCCEEEEEEECCEECCCCCHHHHHHHHHCCC
SVSPIFSQNSPIGLMTLEEFQKTQENFNASLLSSELTTKIF
CCCEEECCCCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362