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The map label for this gene is ffh

Identifier: 15835651

GI number: 15835651

Start: 146990

End: 148336

Strand: Direct

Name: ffh

Synonym: CPj0115

Alternate gene names: 15835651

Gene position: 146990-148336 (Clockwise)

Preceding gene: 15835650

Following gene: 15835652

Centisome position: 11.98

GC content: 38.75

Gene sequence:

>1347_bases
ATGATTAATTCTTTATCGCAAAAGCTATCTTCTATTTTTTCTTTTTTGGTTTCTTCTCGTAGAATTAATGAAGAAAATAT
TTCCGAATCTATTAGAGAAGTTCGTCTGGCTCTCTTGGATGCCGATGTAAATTATCATGTAGTTAAGGATTTTATTTCTA
AAGTTAAAGAAAAAATCCTTGGAGAAGAGATCTGGAAGCATGTTTCCCCAGGGCAACAGTTTATACGTTGTTTGCATGAG
GAATTAGTAGCATTTTTAAGCGATGGAAGAGAAGAGTTTACTATTCAGAAGACGCCTTCGATCATCCTTCTTTGCGGACT
CCAGGGGGCAGGAAAAACAACAACAGCTGCTAAGCTTGCTGATTATGTAATTAAGAATAAGAAAGCAAAAAAAGTCCTTG
TGGTTCCTTGTGATCTCAAAAGATTCGCTGCTGTAGATCAATTAAAAATTTTGGTTGCTCAAACGAAAGCTGAATTTTAC
CAAAGTCAAGAGAACAAGCCTATTGATGTTGTTGTTAAAGCGCTTGCATATGCTAAAGAAAATGGTCATGATTTTGTGAT
TCTGGATACTGCAGGGCGTCTCAATATAGATAACGAGCTTATGGAAGAGCTGACGGCGATACAAAAAGTTTCTCAAGCTA
ATGAGCGTCTTTTTGTGATGAATGTAGCTATGGGGCAAGATGTTTTAGCAACAGTGCAAGCTTTTGATCAGTCTTTAGAT
CTTACAGGCGTGATTCTTTCCATGACTGATGGAGATGCTCGAGCAGGCGCTGTTTTCTCAATTAAGCACGTCCTTGGTAA
GCCCATTAAATTTGAAGGATGCGGAGAACGCATTCAAGATCTTCGTTCATTCGATCCTCAATCTATGGCGGAACGCATTC
TTGGAATGGGGGATACCATAAATTTTGTTAAAGAAATGCGCGAGTATATTTCTGAGGAAGAAGACGCTGAGCTAGGTAAA
AAACTAGTTACTGCGGCTTTTACTTATGAAGACTATTATAAACAGATGAAAGCATTTCGTCGCATGGGACCTCTAAGAAA
ACTTTTGGGAATGATGCCTGGTTTTAATAATGCGAAACCTAGCCAAAAGGAAATCGAGGATTCTGAACAACAGATGAAAA
GAACGGAGGCGATTATCCTGTCCATGACTCCTGAAGAGAGAAAGGAGTTGGTGGAATTGGATATGAGCCGTATGAAGAGG
ATTGCTTCTGGTTGTGGTTTAACTTTAGGCGACGTGAACCAGTTTCGAAAACAGATGTCGCAATCGAAAAAATTTTTTAA
AGGAATGTCTAAAGGCAAGATGGAACAAGTTAGGAAAAAAATGTCAGGAGGAAATCAGTGGCGTTAA

Upstream 100 bases:

>100_bases
TCCATCAAGATTTGTCTGGACGCGATAGAATTTTTTTTCTTGAAATGGATGGGAGAGATCCTGTATCCTCGGGGGCTTAT
TCTTGATTTTTTCTGGATAA

Downstream 100 bases:

>100_bases
AAATTCGTTTAAGACAGCAAGGGCGTAGAAATCATGTTGTTTATAGATTAGTGCTCGCAGATGTCGAGTCTCCTCGTGAT
GGTAAATACATAGAATTATT

Product: signal recognition particle GTPase

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MINSLSQKLSSIFSFLVSSRRINEENISESIREVRLALLDADVNYHVVKDFISKVKEKILGEEIWKHVSPGQQFIRCLHE
ELVAFLSDGREEFTIQKTPSIILLCGLQGAGKTTTAAKLADYVIKNKKAKKVLVVPCDLKRFAAVDQLKILVAQTKAEFY
QSQENKPIDVVVKALAYAKENGHDFVILDTAGRLNIDNELMEELTAIQKVSQANERLFVMNVAMGQDVLATVQAFDQSLD
LTGVILSMTDGDARAGAVFSIKHVLGKPIKFEGCGERIQDLRSFDPQSMAERILGMGDTINFVKEMREYISEEEDAELGK
KLVTAAFTYEDYYKQMKAFRRMGPLRKLLGMMPGFNNAKPSQKEIEDSEQQMKRTEAIILSMTPEERKELVELDMSRMKR
IASGCGLTLGDVNQFRKQMSQSKKFFKGMSKGKMEQVRKKMSGGNQWR

Sequences:

>Translated_448_residues
MINSLSQKLSSIFSFLVSSRRINEENISESIREVRLALLDADVNYHVVKDFISKVKEKILGEEIWKHVSPGQQFIRCLHE
ELVAFLSDGREEFTIQKTPSIILLCGLQGAGKTTTAAKLADYVIKNKKAKKVLVVPCDLKRFAAVDQLKILVAQTKAEFY
QSQENKPIDVVVKALAYAKENGHDFVILDTAGRLNIDNELMEELTAIQKVSQANERLFVMNVAMGQDVLATVQAFDQSLD
LTGVILSMTDGDARAGAVFSIKHVLGKPIKFEGCGERIQDLRSFDPQSMAERILGMGDTINFVKEMREYISEEEDAELGK
KLVTAAFTYEDYYKQMKAFRRMGPLRKLLGMMPGFNNAKPSQKEIEDSEQQMKRTEAIILSMTPEERKELVELDMSRMKR
IASGCGLTLGDVNQFRKQMSQSKKFFKGMSKGKMEQVRKKMSGGNQWR
>Mature_448_residues
MINSLSQKLSSIFSFLVSSRRINEENISESIREVRLALLDADVNYHVVKDFISKVKEKILGEEIWKHVSPGQQFIRCLHE
ELVAFLSDGREEFTIQKTPSIILLCGLQGAGKTTTAAKLADYVIKNKKAKKVLVVPCDLKRFAAVDQLKILVAQTKAEFY
QSQENKPIDVVVKALAYAKENGHDFVILDTAGRLNIDNELMEELTAIQKVSQANERLFVMNVAMGQDVLATVQAFDQSLD
LTGVILSMTDGDARAGAVFSIKHVLGKPIKFEGCGERIQDLRSFDPQSMAERILGMGDTINFVKEMREYISEEEDAELGK
KLVTAAFTYEDYYKQMKAFRRMGPLRKLLGMMPGFNNAKPSQKEIEDSEQQMKRTEAIILSMTPEERKELVELDMSRMKR
IASGCGLTLGDVNQFRKQMSQSKKFFKGMSKGKMEQVRKKMSGGNQWR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=461, Percent_Identity=30.58568329718, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI226371618, Length=390, Percent_Identity=30, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI23308697, Length=312, Percent_Identity=24.0384615384615, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI295424842, Length=312, Percent_Identity=24.0384615384615, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI89061728, Length=150, Percent_Identity=29.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788963, Length=421, Percent_Identity=39.4299287410926, Blast_Score=321, Evalue=5e-89,
Organism=Escherichia coli, GI1789874, Length=275, Percent_Identity=30.1818181818182, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17539958, Length=452, Percent_Identity=30.3097345132743, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=319, Percent_Identity=25.3918495297806, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325345, Length=396, Percent_Identity=32.8282828282828, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6320498, Length=330, Percent_Identity=24.5454545454545, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647949, Length=414, Percent_Identity=29.4685990338164, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24641198, Length=319, Percent_Identity=25.0783699059561, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 50609; Mature: 50609

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSLSQKLSSIFSFLVSSRRINEENISESIREVRLALLDADVNYHVVKDFISKVKEKIL
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GEEIWKHVSPGQQFIRCLHEELVAFLSDGREEFTIQKTPSIILLCGLQGAGKTTTAAKLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCEEEEECCCCCCCCHHHHHHH
DYVIKNKKAKKVLVVPCDLKRFAAVDQLKILVAQTKAEFYQSQENKPIDVVVKALAYAKE
HHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
NGHDFVILDTAGRLNIDNELMEELTAIQKVSQANERLFVMNVAMGQDVLATVQAFDQSLD
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHCHHHHHHHHHHHHCCC
LTGVILSMTDGDARAGAVFSIKHVLGKPIKFEGCGERIQDLRSFDPQSMAERILGMGDTI
CCEEEEEECCCCCCCCHHEEEHHHHCCCCEECCHHHHHHHHHCCCHHHHHHHHHCCCCHH
NFVKEMREYISEEEDAELGKKLVTAAFTYEDYYKQMKAFRRMGPLRKLLGMMPGFNNAKP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
SQKEIEDSEQQMKRTEAIILSMTPEERKELVELDMSRMKRIASGCGLTLGDVNQFRKQMS
CHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSKKFFKGMSKGKMEQVRKKMSGGNQWR
HHHHHHHCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MINSLSQKLSSIFSFLVSSRRINEENISESIREVRLALLDADVNYHVVKDFISKVKEKIL
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GEEIWKHVSPGQQFIRCLHEELVAFLSDGREEFTIQKTPSIILLCGLQGAGKTTTAAKLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCEEEEECCCCCCCCHHHHHHH
DYVIKNKKAKKVLVVPCDLKRFAAVDQLKILVAQTKAEFYQSQENKPIDVVVKALAYAKE
HHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
NGHDFVILDTAGRLNIDNELMEELTAIQKVSQANERLFVMNVAMGQDVLATVQAFDQSLD
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHCHHHHHHHHHHHHCCC
LTGVILSMTDGDARAGAVFSIKHVLGKPIKFEGCGERIQDLRSFDPQSMAERILGMGDTI
CCEEEEEECCCCCCCCHHEEEHHHHCCCCEECCHHHHHHHHHCCCHHHHHHHHHCCCCHH
NFVKEMREYISEEEDAELGKKLVTAAFTYEDYYKQMKAFRRMGPLRKLLGMMPGFNNAKP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
SQKEIEDSEQQMKRTEAIILSMTPEERKELVELDMSRMKRIASGCGLTLGDVNQFRKQMS
CHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSKKFFKGMSKGKMEQVRKKMSGGNQWR
HHHHHHHCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12397186; 8763945 [H]