Click here to switch to the map view.

The map label for this gene is ileS

Identifier: 15835645

GI number: 15835645

Start: 138366

End: 141497

Strand: Direct

Name: ileS

Synonym: CPj0109

Alternate gene names: 15835645

Gene position: 138366-141497 (Clockwise)

Preceding gene: 15835642

Following gene: 15835648

Centisome position: 11.28

GC content: 39.34

Gene sequence:

>3132_bases
ATGACAGCAGATGAGGTAGGGAAAAATAGCTTTGCAAAAAAAGAAGAACAGGTTTTGAAGTTTTGGAAAGACAATCAAAT
TTTTGAAAAGTCTTTGCAAAATCGTCAGGGAAAAACCCTATATTCTTTCTATGACGGCCCTCCTTTTGCTACAGGTCTTC
CACATTACGGTCACTTATTAGCAAGTACCATTAAGGATGTTGTTGGACGCTATGCTACCATGGACGGGTACTATGTGCCG
CGACGTTTTGGCTGGGATTGCCATGGGGTTCCTGTGGAATATGAGGTGGAAAAGTCTCTGAGTTTAACAGCACCCGGAGC
CATCGAAGATTTTGGTATAGCATCCTTTAACGAAGAGTGTCGTAAAATCGTATTTAGATACGTTCACGAGTGGGAATACT
ATATCAATCGTATAGGACGTTGGGTAGATTTTTCTTCTACTTGGAAAACTATGGACGCTTCTTTTATGGAAAGTGTCTGG
TGGGTTTTCCAATCTCTATATAACCAAGGATTAGTGTACGAAGGTACAAAAGTTGTCCCTTTTTCAACAGCATTAGGAAC
ACCTCTCTCTAATTTTGAAGCAAGCCAAAATTATAAAGAAGTCGATGACCCGTCTCTTGTTGTAAGAATGCCTCTTCAGA
ATGATTCCGCATCCTTGCTTGTATGGACAACGACTCCATGGACATTGCCTTCTAATATGGCTATAGCTGTAGGGGAAACT
CTGGTTTATGTCCGTATTCAAGATAAAAAAAGTGGAGAGCAGTGGATCCTAAGTCAGGGATGTGTTTCTCGTTGGTTTTC
AAATCCAGAAGAATTTGTAATTTTAGAGAGTTTTTCTGGGAAAGATCTTGTTGGTAGGACTTATGAGCCCCCTTTTACTT
TTTTCCAATCTAAGCGAGAGGAAGGAGCTTTTCGTGTCATTGCAGCTTCGTTTGTTGAGGAAAGTGAAGGAACAGGAGTC
GTACATATGGCTCCAGCGTTTGGTGAAGGAGACTTTTTAGTTTGTAAGGAGAACCATGTTCCTTTAGTCTGTCCTGTAGA
TGCTCACGGAAGTTTTACAGAAGAAATACCTCAATATCAAGGGCAATACATTAAACATGCTGACAAGGAAATCATCAAGT
TCTTGAAGAAAGAAGGAAGGATTTTTTACCACGGAACAGTAAAACACCGGTATCCTTTCTGTTGGAGAACGGATACTCCT
TTGATTTATAAAGCCGTGAATTCTTGGTTCGTCGCTGTAGAAAAGATTAAAGATAAGATGCTTCGTGCTAACAGCTCGAT
CCATTGGGTTCCTGAACATATCCAAGAAGGGCGTTTTGGAAAATGGTTGGAAGGCGCTCGTGATTGGGCTATCAGTAGAA
ATCGTTATTGGGGAACGCCAATTCCGATTTGGAAAAGTGCTGATGGCGAGATTCTTGTTGTAGGATCTATCCGAGAGCTA
GAAGAACTTACAGGAACTCAGATCACAGATATTCATAGGCATTTTATTGATGATTTGAACATTGTCAAAGATGGCAAGCC
CTTTCATCGAATTCCCTACGTTTTTGATTGCTGGTTCGACTCTGGAGCGATGCCTTATGCCCAAAATCATTATCCTTTTG
AAAATCAAAAGGAAACCGAAGAGGCATTTCCTGCAGACTTTATTGCTGAAGGGTTGGATCAGACGCGAGGATGGTTTTAT
ACTCTCACAGTGATTTCTGCAATTTTATTTGATCGTCCTGCATTTCGTAATGCCATTGTGAATGGGATTATTCTTGCAGA
AGACGGCAATAAAATGTCAAAACGTCTAAATAATTACCCTAGTCCTAAATACGTTTTAGATACTTATGGAGCTGACGCGC
TTCGTCTATATTTGCTTCATAGTGTTGTCGTAAAGGCTGAAGATCTTCGCTTTTCTGATAAAGGAATCGAGGGTGTTTTG
AAGCAAATCCTTCTTCCTCTAACGAACGTACTTTCCTTTTTTAATACCTATGCCGAGCTGTATGGTTTTGATCCGAAATC
ACAAGATATAGAACCAGCTTATACAGAGATTGATCAATGGATTTTATCCAATTTGTATAGTGTTGTAGGTAAAGTTCGTG
AGAGCATGAGTCAGTATCATTTAAACTTTGCTGTAGAACCCTTTGTGACCTTTATTGATGATCTGACTAACTGGTATATA
CGTCGCTGTCGTAGACGTTTTTGGGAAGCTGAAGATACTCCTGACCGTAGAGCTGCATTTTCTACTTTATATGAAGTTCT
CACAGTTTTTTGTAAGGTAATTGCTCCCTTCGTTCCTTTTCTTGCCGAAGATATCTATCAGAAGTTGAAGTTAGAAAAGG
AACCTGAATCTGTTCATCTCTGTGATTTTCCTCAAGTCGAGATGGATAAAATTCTCCCTGATCTAGAAAAGCGTATGCAC
GATATTCGGGAAATCGTAGGTTTAGGCCATTCTTTAAGAAAAGAACACAAGTTAAAAGTTCGTCAGCCTTTAGCAAACTT
TTATGTTGTCGGGTCTAAAGATAGATTGTCGCTTCTAAAAACATTTGAAGGGTTGATTGCTGAAGAGCTGAATGTGAAAA
ATGTGATTTTCTATGAAGAAGCTCCGAGTTTCATTTATACTACCGTCAAACCTAATTTTCGTATGCTTGGGAAAAAAGTT
GGATCTAAGATGAAAGAGGTCCAAAAAGCTCTCAGTGAACTGCCAAACAATGCTATAGATAAGCTGATTCAGGAAGAAAC
ATGGGTTTTAACCATTGATGATAGAGAAATAGCTTTGGATGGTGATGACGTCGTGATTTGTCGTCACACAGATCCTGGAT
ATATTGCCCGTAGTTCCGCTCTATTTAGTGTGATTTTAGATTGCCAGTTAAGAGAACCTCTTATAGTCGAAGGTATAGCA
AGAGAGCTAGTCAATAAGATTAATACTATGCGTCGAAATCAACAACTTCATGTTTCTGACCGCATCGCATTAAGAATAAA
AACCACAGAGGCTGTTCATCGCGCTTTCTTGGATTATGAAAACTATATTTGCGAAGAAACGTTAATTATAGCCTATGATT
TTACTCAGGATTCTGATTTCCAAGGGGAAAACTGGGATATTAATGGACATGCAACGCAAATTGAAATTACAGTTAGTTCT
ATAGATTCTTAG

Upstream 100 bases:

>100_bases
AACTTCTTAGAGATCTCTAGAGAGGTGGGCTATGGACGAAAACCTAAAAAACCTCTATTGTAAATATGTTTTCATATCAA
AATGTTCCTAAAGGCAAAAG

Downstream 100 bases:

>100_bases
AGATTTTCTAGAAACAACTGAAAAACCATAAGAATGGTTATTTCTTGTGGTTTTTCTCCTCTTTCTTAGGAAAGAGTCTG
CGTCGTTTTTGATAGTAGAC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1043; Mature: 1042

Protein sequence:

>1043_residues
MTADEVGKNSFAKKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYATMDGYYVP
RRFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEECRKIVFRYVHEWEYYINRIGRWVDFSSTWKTMDASFMESVW
WVFQSLYNQGLVYEGTKVVPFSTALGTPLSNFEASQNYKEVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGET
LVYVRIQDKKSGEQWILSQGCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKREEGAFRVIAASFVEESEGTGV
VHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQGQYIKHADKEIIKFLKKEGRIFYHGTVKHRYPFCWRTDTP
LIYKAVNSWFVAVEKIKDKMLRANSSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIREL
EELTGTQITDIHRHFIDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHYPFENQKETEEAFPADFIAEGLDQTRGWFY
TLTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKGIEGVL
KQILLPLTNVLSFFNTYAELYGFDPKSQDIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFIDDLTNWYI
RRCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPESVHLCDFPQVEMDKILPDLEKRMH
DIREIVGLGHSLRKEHKLKVRQPLANFYVVGSKDRLSLLKTFEGLIAEELNVKNVIFYEEAPSFIYTTVKPNFRMLGKKV
GSKMKEVQKALSELPNNAIDKLIQEETWVLTIDDREIALDGDDVVICRHTDPGYIARSSALFSVILDCQLREPLIVEGIA
RELVNKINTMRRNQQLHVSDRIALRIKTTEAVHRAFLDYENYICEETLIIAYDFTQDSDFQGENWDINGHATQIEITVSS
IDS

Sequences:

>Translated_1043_residues
MTADEVGKNSFAKKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYATMDGYYVP
RRFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEECRKIVFRYVHEWEYYINRIGRWVDFSSTWKTMDASFMESVW
WVFQSLYNQGLVYEGTKVVPFSTALGTPLSNFEASQNYKEVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGET
LVYVRIQDKKSGEQWILSQGCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKREEGAFRVIAASFVEESEGTGV
VHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQGQYIKHADKEIIKFLKKEGRIFYHGTVKHRYPFCWRTDTP
LIYKAVNSWFVAVEKIKDKMLRANSSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIREL
EELTGTQITDIHRHFIDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHYPFENQKETEEAFPADFIAEGLDQTRGWFY
TLTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKGIEGVL
KQILLPLTNVLSFFNTYAELYGFDPKSQDIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFIDDLTNWYI
RRCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPESVHLCDFPQVEMDKILPDLEKRMH
DIREIVGLGHSLRKEHKLKVRQPLANFYVVGSKDRLSLLKTFEGLIAEELNVKNVIFYEEAPSFIYTTVKPNFRMLGKKV
GSKMKEVQKALSELPNNAIDKLIQEETWVLTIDDREIALDGDDVVICRHTDPGYIARSSALFSVILDCQLREPLIVEGIA
RELVNKINTMRRNQQLHVSDRIALRIKTTEAVHRAFLDYENYICEETLIIAYDFTQDSDFQGENWDINGHATQIEITVSS
IDS
>Mature_1042_residues
TADEVGKNSFAKKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYATMDGYYVPR
RFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEECRKIVFRYVHEWEYYINRIGRWVDFSSTWKTMDASFMESVWW
VFQSLYNQGLVYEGTKVVPFSTALGTPLSNFEASQNYKEVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGETL
VYVRIQDKKSGEQWILSQGCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKREEGAFRVIAASFVEESEGTGVV
HMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQGQYIKHADKEIIKFLKKEGRIFYHGTVKHRYPFCWRTDTPL
IYKAVNSWFVAVEKIKDKMLRANSSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIRELE
ELTGTQITDIHRHFIDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHYPFENQKETEEAFPADFIAEGLDQTRGWFYT
LTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKGIEGVLK
QILLPLTNVLSFFNTYAELYGFDPKSQDIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFIDDLTNWYIR
RCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPESVHLCDFPQVEMDKILPDLEKRMHD
IREIVGLGHSLRKEHKLKVRQPLANFYVVGSKDRLSLLKTFEGLIAEELNVKNVIFYEEAPSFIYTTVKPNFRMLGKKVG
SKMKEVQKALSELPNNAIDKLIQEETWVLTIDDREIALDGDDVVICRHTDPGYIARSSALFSVILDCQLREPLIVEGIAR
ELVNKINTMRRNQQLHVSDRIALRIKTTEAVHRAFLDYENYICEETLIIAYDFTQDSDFQGENWDINGHATQIEITVSSI
DS

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1014, Percent_Identity=45.5621301775148, Blast_Score=915, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1014, Percent_Identity=45.5621301775148, Blast_Score=915, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=789, Percent_Identity=29.404309252218, Blast_Score=304, Evalue=3e-82,
Organism=Homo sapiens, GI5454158, Length=785, Percent_Identity=22.0382165605096, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI268370293, Length=879, Percent_Identity=21.9567690557452, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI268370295, Length=860, Percent_Identity=21.9767441860465, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI268370297, Length=879, Percent_Identity=21.9567690557452, Blast_Score=137, Evalue=6e-32,
Organism=Escherichia coli, GI2367096, Length=796, Percent_Identity=26.8844221105528, Blast_Score=303, Evalue=5e-83,
Organism=Escherichia coli, GI1790708, Length=852, Percent_Identity=21.1267605633803, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17541896, Length=1003, Percent_Identity=44.6660019940179, Blast_Score=863, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=888, Percent_Identity=24.6621621621622, Blast_Score=222, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17510661, Length=835, Percent_Identity=24.311377245509, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI72001587, Length=802, Percent_Identity=23.0673316708229, Blast_Score=148, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1067, Percent_Identity=42.174320524836, Blast_Score=828, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=791, Percent_Identity=25.031605562579, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321531, Length=770, Percent_Identity=21.6883116883117, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574730, Length=1008, Percent_Identity=43.9484126984127, Blast_Score=865, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1008, Percent_Identity=43.9484126984127, Blast_Score=865, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1008, Percent_Identity=43.9484126984127, Blast_Score=865, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=800, Percent_Identity=27.375, Blast_Score=267, Evalue=3e-71,
Organism=Drosophila melanogaster, GI17864482, Length=910, Percent_Identity=22.967032967033, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24653289, Length=910, Percent_Identity=22.967032967033, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI21355675, Length=553, Percent_Identity=20.6148282097649, Blast_Score=111, Evalue=3e-24,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_CHLPN (Q9Z972)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C81552
- PIR:   E72118
- PIR:   F86504
- RefSeq:   NP_224317.1
- RefSeq:   NP_300169.1
- RefSeq:   NP_445207.1
- RefSeq:   NP_876386.1
- ProteinModelPortal:   Q9Z972
- SMR:   Q9Z972
- GeneID:   1466793
- GeneID:   894633
- GeneID:   918769
- GeneID:   963852
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0665
- KEGG:   cpn:CPn0109
- KEGG:   cpt:CpB0110
- TIGR:   CP_0665
- HOGENOM:   HBG577712
- OMA:   VEYEVEK
- PhylomeDB:   Q9Z972
- ProtClustDB:   PRK06039
- BioCyc:   CPNE115711:CP_0665-MONOMER
- BioCyc:   CPNE115713:CPN0109-MONOMER
- BioCyc:   CPNE138677:CPJ0109-MONOMER
- BioCyc:   CPNE182082:CPB0110-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 120288; Mature: 120157

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 594-594

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADEVGKNSFAKKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLL
CCCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
ASTIKDVVGRYATMDGYYVPRRFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEEC
HHHHHHHHHHHCCCCCEECCHHCCCCCCCCCEEEECCCCEEECCCCCCHHCCCCHHHHHH
RKIVFRYVHEWEYYINRIGRWVDFSSTWKTMDASFMESVWWVFQSLYNQGLVYEGTKVVP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEE
FSTALGTPLSNFEASQNYKEVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGET
EHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEEEECCE
LVYVRIQDKKSGEQWILSQGCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKRE
EEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCC
EGAFRVIAASFVEESEGTGVVHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQ
CCCEEEHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHC
GQYIKHADKEIIKFLKKEGRIFYHGTVKHRYPFCWRTDTPLIYKAVNSWFVAVEKIKDKM
CHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
LRANSSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIREL
HHCCCCCEECHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEEECHHHH
EELTGTQITDIHRHFIDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHYPFENQKETE
HHHCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHH
EAFPADFIAEGLDQTRGWFYTLTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYP
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCHHHHHHCCCC
SPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKGIEGVLKQILLPLTNVLSFFNTYAEL
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGFDPKSQDIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFIDDLTNWYI
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHH
RRCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPESVHL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
CDFPQVEMDKILPDLEKRMHDIREIVGLGHSLRKEHKLKVRQPLANFYVVGSKDRLSLLK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
TFEGLIAEELNVKNVIFYEEAPSFIYTTVKPNFRMLGKKVGSKMKEVQKALSELPNNAID
HHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KLIQEETWVLTIDDREIALDGDDVVICRHTDPGYIARSSALFSVILDCQLREPLIVEGIA
HHHCCCCEEEEECCCEEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHCCCCCHHHHHHH
RELVNKINTMRRNQQLHVSDRIALRIKTTEAVHRAFLDYENYICEETLIIAYDFTQDSDF
HHHHHHHHHHHCCCCEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
QGENWDINGHATQIEITVSSIDS
CCCCCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
TADEVGKNSFAKKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLL
CCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
ASTIKDVVGRYATMDGYYVPRRFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEEC
HHHHHHHHHHHCCCCCEECCHHCCCCCCCCCEEEECCCCEEECCCCCCHHCCCCHHHHHH
RKIVFRYVHEWEYYINRIGRWVDFSSTWKTMDASFMESVWWVFQSLYNQGLVYEGTKVVP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEE
FSTALGTPLSNFEASQNYKEVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGET
EHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEEEECCE
LVYVRIQDKKSGEQWILSQGCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKRE
EEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCC
EGAFRVIAASFVEESEGTGVVHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQ
CCCEEEHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHC
GQYIKHADKEIIKFLKKEGRIFYHGTVKHRYPFCWRTDTPLIYKAVNSWFVAVEKIKDKM
CHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
LRANSSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIREL
HHCCCCCEECHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEEECHHHH
EELTGTQITDIHRHFIDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHYPFENQKETE
HHHCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHH
EAFPADFIAEGLDQTRGWFYTLTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYP
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCHHHHHHCCCC
SPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKGIEGVLKQILLPLTNVLSFFNTYAEL
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGFDPKSQDIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFIDDLTNWYI
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHH
RRCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPESVHL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
CDFPQVEMDKILPDLEKRMHDIREIVGLGHSLRKEHKLKVRQPLANFYVVGSKDRLSLLK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
TFEGLIAEELNVKNVIFYEEAPSFIYTTVKPNFRMLGKKVGSKMKEVQKALSELPNNAID
HHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KLIQEETWVLTIDDREIALDGDDVVICRHTDPGYIARSSALFSVILDCQLREPLIVEGIA
HHHCCCCEEEEECCCEEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHCCCCCHHHHHHH
RELVNKINTMRRNQQLHVSDRIALRIKTTEAVHRAFLDYENYICEETLIIAYDFTQDSDF
HHHHHHHHHHHCCCCEEECCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
QGENWDINGHATQIEITVSSIDS
CCCCCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362