Click here to switch to the map view.

The map label for this gene is murA

Identifier: 15835355

GI number: 15835355

Start: 881955

End: 883283

Strand: Reverse

Name: murA

Synonym: TC0740

Alternate gene names: 15835355

Gene position: 883283-881955 (Counterclockwise)

Preceding gene: 15835357

Following gene: 15835349

Centisome position: 82.32

GC content: 42.36

Gene sequence:

>1329_bases
ATGCCTGGTATTAAAGTTTTTGGAGGAACTGTCCTACAAGGGTCCGTACGTGTGTCAGGGGCTAAAAACGCTACAACTAA
ATTACTTGTGGCATCCTTACTTTCAGATAAGCGTACCATTTTGAAGAACGTTCCTAATATAGAGGATGTTCAACAAACGG
TTGATCTGTGCCGGGCTTTAGGGGCAATTGTAGATTGGGACAAGCAAGCGCAAGTTATTGACATTCACACGCCACGTATT
TTGTTATCCAAGGTTCCTCCGCAATTTTCTTGCGTAAACCGCATTCCTATTTTGCTGTTAGGTGCTTTGCTACGTCGTTG
TCCCTATGGAATTTTTGTTCCTATTTTGGGAGGAGATGCCATTGGTCCACGCACATTACATTTTCATCTCGAAGGGTTAA
AGAAACTTGGTGCAGAGATTATTGTGAGTGATGAAGGATATTGGGCAGCTGCTCCAGATGGTCTCATTGGAGCGCATATT
ACTTTGCCTTATCCTTCTGTAGGAGCTACAGAAAATCTTATCCTTGCATCTGTCGGTGCTCAAGGGAGAACGATTATTAA
GAATGCAGCTCTGGAAGTAGAGATTATTGATCTAATTGTTTTCTTACAGAAAGCTGGTGTAGAGATCACGACTGATAATG
ATAAAACAATCGAAATTTTTGGTTGCCAGGACTTTTATTCTGTTGAACACTCTATTATTCCAGATAAAATCGAAGCGGCT
TCTTTTGGTATGGCTGCAGTTGTTTCTCAAGGGAGAGTTTTTGTAGAGCATGCGCGTCATGAGCATATGATTCCTTTCTT
AAAAGCCCTAAGATCCATAGGCGGAGGGTTTTCAGTTCAAGAAAATGGCATCGAATTTTTTTATGATAAACCTTTAAAAG
GTGGGGTGCTCTTAGAGACAGATGTACATCCAGGGTTTATTACGGATTGGCAACAGCCTTTTGCTGTTTTACTGTCTCAA
GCAGAAGGCTGTTCTGTTATCCATGAAACGGTGCATGAGAATCGACTGGGGTATCTGAGTGGTTTAGCAAAAATGGGCGC
TCATTGCGATTTATTTCATGAATGTCTAAGTGCCAAGTCTTGTCGATACTCTACAGGGAATCATCCGCATAGTGCAGTCA
TTCATGGACCGACTCCTTTGCAGGCAACACATTTAGTGATCCCCGATTTGCGTGCGGGGTTTGCCTATGTTATGGCAGCT
CTTATTGCCGAGGGAGGGGTTTCTAAGATTGAGAATACAAAGATGTTAGACCGAGGGTACACAGACTGGCTAGGGAATTT
AGAAAGACTAGGAGCCAAAATACTCACAGAGAAAACAAGATGTGTCTAA

Upstream 100 bases:

>100_bases
TTGTTTGTTAATAAGATGTCTTTTAGAAAAATAAAGTTTTCGTGAAAAATAACAGCATACCGGTTAACGTTTGTGAAGAA
ATGCAATTAAGGGAATTGAA

Downstream 100 bases:

>100_bases
GGGAAGGATTTTAGACCTTCCCTTAGATTGTTTTTACAGGTGATCTAGAGTCTTCAGACCTAATAGGTGCATGCCTGTTT
CCAAGGTTTTTTCTGTCAGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MPGIKVFGGTVLQGSVRVSGAKNATTKLLVASLLSDKRTILKNVPNIEDVQQTVDLCRALGAIVDWDKQAQVIDIHTPRI
LLSKVPPQFSCVNRIPILLLGALLRRCPYGIFVPILGGDAIGPRTLHFHLEGLKKLGAEIIVSDEGYWAAAPDGLIGAHI
TLPYPSVGATENLILASVGAQGRTIIKNAALEVEIIDLIVFLQKAGVEITTDNDKTIEIFGCQDFYSVEHSIIPDKIEAA
SFGMAAVVSQGRVFVEHARHEHMIPFLKALRSIGGGFSVQENGIEFFYDKPLKGGVLLETDVHPGFITDWQQPFAVLLSQ
AEGCSVIHETVHENRLGYLSGLAKMGAHCDLFHECLSAKSCRYSTGNHPHSAVIHGPTPLQATHLVIPDLRAGFAYVMAA
LIAEGGVSKIENTKMLDRGYTDWLGNLERLGAKILTEKTRCV

Sequences:

>Translated_442_residues
MPGIKVFGGTVLQGSVRVSGAKNATTKLLVASLLSDKRTILKNVPNIEDVQQTVDLCRALGAIVDWDKQAQVIDIHTPRI
LLSKVPPQFSCVNRIPILLLGALLRRCPYGIFVPILGGDAIGPRTLHFHLEGLKKLGAEIIVSDEGYWAAAPDGLIGAHI
TLPYPSVGATENLILASVGAQGRTIIKNAALEVEIIDLIVFLQKAGVEITTDNDKTIEIFGCQDFYSVEHSIIPDKIEAA
SFGMAAVVSQGRVFVEHARHEHMIPFLKALRSIGGGFSVQENGIEFFYDKPLKGGVLLETDVHPGFITDWQQPFAVLLSQ
AEGCSVIHETVHENRLGYLSGLAKMGAHCDLFHECLSAKSCRYSTGNHPHSAVIHGPTPLQATHLVIPDLRAGFAYVMAA
LIAEGGVSKIENTKMLDRGYTDWLGNLERLGAKILTEKTRCV
>Mature_441_residues
PGIKVFGGTVLQGSVRVSGAKNATTKLLVASLLSDKRTILKNVPNIEDVQQTVDLCRALGAIVDWDKQAQVIDIHTPRIL
LSKVPPQFSCVNRIPILLLGALLRRCPYGIFVPILGGDAIGPRTLHFHLEGLKKLGAEIIVSDEGYWAAAPDGLIGAHIT
LPYPSVGATENLILASVGAQGRTIIKNAALEVEIIDLIVFLQKAGVEITTDNDKTIEIFGCQDFYSVEHSIIPDKIEAAS
FGMAAVVSQGRVFVEHARHEHMIPFLKALRSIGGGFSVQENGIEFFYDKPLKGGVLLETDVHPGFITDWQQPFAVLLSQA
EGCSVIHETVHENRLGYLSGLAKMGAHCDLFHECLSAKSCRYSTGNHPHSAVIHGPTPLQATHLVIPDLRAGFAYVMAAL
IAEGGVSKIENTKMLDRGYTDWLGNLERLGAKILTEKTRCV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=435, Percent_Identity=34.7126436781609, Blast_Score=211, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47885; Mature: 47754

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGIKVFGGTVLQGSVRVSGAKNATTKLLVASLLSDKRTILKNVPNIEDVQQTVDLCRAL
CCCCEEECCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GAIVDWDKQAQVIDIHTPRILLSKVPPQFSCVNRIPILLLGALLRRCPYGIFVPILGGDA
HHHHCCCCCCEEEEECCCHHHHHCCCCCHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCC
IGPRTLHFHLEGLKKLGAEIIVSDEGYWAAAPDGLIGAHITLPYPSVGATENLILASVGA
CCCCEEEEEHHHHHHCCCEEEEECCCCEEECCCCCEEEEEEECCCCCCCCCCEEEEECCC
QGRTIIKNAALEVEIIDLIVFLQKAGVEITTDNDKTIEIFGCQDFYSVEHSIIPDKIEAA
CCCEEHHHCCEEHHHHHHHHHHHHCCEEEECCCCCEEEEEECCHHHHHHHCCCCCHHHHH
SFGMAAVVSQGRVFVEHARHEHMIPFLKALRSIGGGFSVQENGIEFFYDKPLKGGVLLET
HCCHHHHHHCCCCEEHHHCCCHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCEEEEE
DVHPGFITDWQQPFAVLLSQAEGCSVIHETVHENRLGYLSGLAKMGAHCDLFHECLSAKS
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCC
CRYSTGNHPHSAVIHGPTPLQATHLVIPDLRAGFAYVMAALIAEGGVSKIENTKMLDRGY
CCCCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHCCC
TDWLGNLERLGAKILTEKTRCV
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGIKVFGGTVLQGSVRVSGAKNATTKLLVASLLSDKRTILKNVPNIEDVQQTVDLCRAL
CCCEEECCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GAIVDWDKQAQVIDIHTPRILLSKVPPQFSCVNRIPILLLGALLRRCPYGIFVPILGGDA
HHHHCCCCCCEEEEECCCHHHHHCCCCCHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCC
IGPRTLHFHLEGLKKLGAEIIVSDEGYWAAAPDGLIGAHITLPYPSVGATENLILASVGA
CCCCEEEEEHHHHHHCCCEEEEECCCCEEECCCCCEEEEEEECCCCCCCCCCEEEEECCC
QGRTIIKNAALEVEIIDLIVFLQKAGVEITTDNDKTIEIFGCQDFYSVEHSIIPDKIEAA
CCCEEHHHCCEEHHHHHHHHHHHHCCEEEECCCCCEEEEEECCHHHHHHHCCCCCHHHHH
SFGMAAVVSQGRVFVEHARHEHMIPFLKALRSIGGGFSVQENGIEFFYDKPLKGGVLLET
HCCHHHHHHCCCCEEHHHCCCHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCEEEEE
DVHPGFITDWQQPFAVLLSQAEGCSVIHETVHENRLGYLSGLAKMGAHCDLFHECLSAKS
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCC
CRYSTGNHPHSAVIHGPTPLQATHLVIPDLRAGFAYVMAALIAEGGVSKIENTKMLDRGY
CCCCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHCCC
TDWLGNLERLGAKILTEKTRCV
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA