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Identifier: 15835334

GI number: 15835334

Start: 856717

End: 857769

Strand: Reverse

Name: Not Available

Synonym: TC0719

Alternate gene names: 15835334

Gene position: 857769-856717 (Counterclockwise)

Preceding gene: 15835335

Following gene: 15835331

Centisome position: 79.94

GC content: 37.89

Gene sequence:

>1053_bases
ATGTCTTTATTTGCTAAATTCAAAGCTCAGTGGATGGTTTTACATTCTCGTGAGCTTTGTTCTTATAATCAGGATGGCGG
GCAAACCTCTTTAGACCCAGTTTTTAAAATTATATGTGGTCCCGTTAATTCTGAAATCTCTTACAAGGTGGGGGATTCGT
TGGGGGTTTTTCCGACGAATCCTTCTTCTTTGGTTGATTCCATATTGTCCGTTTTACAGTATGATCCTCATACTGTCGTT
GTTTCTCGACATGCAGATACAACTCTCTCTATTCGAGAATTTCTTATTAGTTATGTAGATCTTGATAAGATTTCGAAAGT
TCTAAAGCCCTTTTTCCCTGAGGATTTGGATGATTCTTGGTCCTTATCTGAAGCGATTCTATTTTATCGTCCCCAGATTT
CTTTAGAAGAATTTGTTCAGGGAATAATGCCTTTATTACCTAGGTTTTACTCCATAGCTTCTTCACCAGAATATTCTCAT
GGACAATTAGAGTTGCTGGTGCGTTGTGTTAGCTTCCCAGGAAAGATGCAACTACGGTATGGATTGTGTTCGGCTTTTTT
ATGTAAAGATTTGCAAGAAGGAACGATTTTTCAAGGGTTTGTACAGCCAACAAAGCATTTTACATTACAACAGAATAGCT
TTGGGAAACCTCTGATTATGATTGGAGCGGGAACAGGAATTGCTCCCTATAAAGGATTTTTACAACATAGATTGTATCAC
CAGGATTTTGGTGCGAACATTCTATTTTTTGGTGAGCGTTTTGAGAAAAGCAACTTTTATTATCGGGATTTTTTGCAGGG
GCTGATTGCTTCAGGGAATCTACAATTGTTCACCGCGTTTTCTAGGGACTCTGAATCTAAAATGTATGTTCAGGATGCAA
TTGAACAGCAAAGGGAACTTATACAAGAAAATTATGAGAAAGGAGCCTTTTTCTTTGTGTGCGGGAAGAAGACCCTTGGG
ATAGAAACTAAACGCGCTTTGGGAAATATTTTAGGTTCAGAGTCAGTACAAGAGCTTGTTTTACAAAAAAGACTGGTTTT
AGACGTATATTAA

Upstream 100 bases:

>100_bases
TTTAGATCCTACAGGAAAAACAATCGATGCTTTGAAGATGTTGTCTTTGCCTGCTGGAGTCGATATTAAAATTAAGGCTG
CTTAATCTTTTGATTTGAGA

Downstream 100 bases:

>100_bases
CGTGGGCAGAATTCCATAACGGTTAAAACGCAGAAACATTGTACGCCATGTCCCTGGCCCATGCTCGTTAGCCCTTCTCC
AGAAGTTGCTGTGATGTTAA

Product: oxidoreductase, FAD-binding

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSLFAKFKAQWMVLHSRELCSYNQDGGQTSLDPVFKIICGPVNSEISYKVGDSLGVFPTNPSSLVDSILSVLQYDPHTVV
VSRHADTTLSIREFLISYVDLDKISKVLKPFFPEDLDDSWSLSEAILFYRPQISLEEFVQGIMPLLPRFYSIASSPEYSH
GQLELLVRCVSFPGKMQLRYGLCSAFLCKDLQEGTIFQGFVQPTKHFTLQQNSFGKPLIMIGAGTGIAPYKGFLQHRLYH
QDFGANILFFGERFEKSNFYYRDFLQGLIASGNLQLFTAFSRDSESKMYVQDAIEQQRELIQENYEKGAFFFVCGKKTLG
IETKRALGNILGSESVQELVLQKRLVLDVY

Sequences:

>Translated_350_residues
MSLFAKFKAQWMVLHSRELCSYNQDGGQTSLDPVFKIICGPVNSEISYKVGDSLGVFPTNPSSLVDSILSVLQYDPHTVV
VSRHADTTLSIREFLISYVDLDKISKVLKPFFPEDLDDSWSLSEAILFYRPQISLEEFVQGIMPLLPRFYSIASSPEYSH
GQLELLVRCVSFPGKMQLRYGLCSAFLCKDLQEGTIFQGFVQPTKHFTLQQNSFGKPLIMIGAGTGIAPYKGFLQHRLYH
QDFGANILFFGERFEKSNFYYRDFLQGLIASGNLQLFTAFSRDSESKMYVQDAIEQQRELIQENYEKGAFFFVCGKKTLG
IETKRALGNILGSESVQELVLQKRLVLDVY
>Mature_349_residues
SLFAKFKAQWMVLHSRELCSYNQDGGQTSLDPVFKIICGPVNSEISYKVGDSLGVFPTNPSSLVDSILSVLQYDPHTVVV
SRHADTTLSIREFLISYVDLDKISKVLKPFFPEDLDDSWSLSEAILFYRPQISLEEFVQGIMPLLPRFYSIASSPEYSHG
QLELLVRCVSFPGKMQLRYGLCSAFLCKDLQEGTIFQGFVQPTKHFTLQQNSFGKPLIMIGAGTGIAPYKGFLQHRLYHQ
DFGANILFFGERFEKSNFYYRDFLQGLIASGNLQLFTAFSRDSESKMYVQDAIEQQRELIQENYEKGAFFFVCGKKTLGI
ETKRALGNILGSESVQELVLQKRLVLDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI10835173, Length=377, Percent_Identity=27.5862068965517, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI7657393, Length=341, Percent_Identity=27.8592375366569, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI221316709, Length=341, Percent_Identity=27.8592375366569, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI127139033, Length=372, Percent_Identity=26.0752688172043, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI221316705, Length=350, Percent_Identity=27.1428571428571, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI221316707, Length=323, Percent_Identity=27.2445820433437, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40254422, Length=207, Percent_Identity=32.8502415458937, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24041029, Length=366, Percent_Identity=26.775956284153, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI169790956, Length=397, Percent_Identity=28.463476070529, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169790958, Length=453, Percent_Identity=27.3730684326711, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789123, Length=360, Percent_Identity=28.3333333333333, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17554134, Length=351, Percent_Identity=28.4900284900285, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17566446, Length=173, Percent_Identity=35.2601156069364, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321143, Length=357, Percent_Identity=27.4509803921569, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325305, Length=185, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321832, Length=125, Percent_Identity=36, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582192, Length=376, Percent_Identity=27.1276595744681, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI17137192, Length=376, Percent_Identity=27.1276595744681, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24660907, Length=212, Percent_Identity=35.377358490566, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24660903, Length=212, Percent_Identity=35.377358490566, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI78706872, Length=346, Percent_Identity=29.4797687861272, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24583543, Length=346, Percent_Identity=29.4797687861272, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706876, Length=346, Percent_Identity=29.4797687861272, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 39735; Mature: 39604

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFAKFKAQWMVLHSRELCSYNQDGGQTSLDPVFKIICGPVNSEISYKVGDSLGVFPTN
CCCHHHHHHHHHEEECHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
PSSLVDSILSVLQYDPHTVVVSRHADTTLSIREFLISYVDLDKISKVLKPFFPEDLDDSW
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
SLSEAILFYRPQISLEEFVQGIMPLLPRFYSIASSPEYSHGQLELLVRCVSFPGKMQLRY
CHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEHHH
GLCSAFLCKDLQEGTIFQGFVQPTKHFTLQQNSFGKPLIMIGAGTGIAPYKGFLQHRLYH
HHHHHHHHHHHHCCCEEHHHHCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
QDFGANILFFGERFEKSNFYYRDFLQGLIASGNLQLFTAFSRDSESKMYVQDAIEQQREL
HCCCCEEEEEECHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
IQENYEKGAFFFVCGKKTLGIETKRALGNILGSESVQELVLQKRLVLDVY
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLFAKFKAQWMVLHSRELCSYNQDGGQTSLDPVFKIICGPVNSEISYKVGDSLGVFPTN
CCHHHHHHHHHEEECHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
PSSLVDSILSVLQYDPHTVVVSRHADTTLSIREFLISYVDLDKISKVLKPFFPEDLDDSW
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
SLSEAILFYRPQISLEEFVQGIMPLLPRFYSIASSPEYSHGQLELLVRCVSFPGKMQLRY
CHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEHHH
GLCSAFLCKDLQEGTIFQGFVQPTKHFTLQQNSFGKPLIMIGAGTGIAPYKGFLQHRLYH
HHHHHHHHHHHHCCCEEHHHHCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
QDFGANILFFGERFEKSNFYYRDFLQGLIASGNLQLFTAFSRDSESKMYVQDAIEQQREL
HCCCCEEEEEECHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
IQENYEKGAFFFVCGKKTLGIETKRALGNILGSESVQELVLQKRLVLDVY
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA