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Identifier: 15835267

GI number: 15835267

Start: 779739

End: 780326

Strand: Direct

Name: Not Available

Synonym: TC0652

Alternate gene names: 15835267

Gene position: 779739-780326 (Clockwise)

Preceding gene: 15835266

Following gene: 15835268

Centisome position: 72.67

GC content: 39.46

Gene sequence:

>588_bases
ATGCCTTACGGAACTCGTTATCCAACATTAGCTTTTCATACAGGAGGCGTTGGCGAATCTGATGACGGAATGCCTCCTCA
ACCTTTTGAAACTTTCTGCTACGATTCGGCCTTACTTCAAGCAAAAATCGAAAATTTCAATATTGTTCCCTACACTTCAG
TTTTACCCAAAGAATTATTTGGAAACATCCTTCCTGTTGATCAATGTACAAAATTTTTCAAGCATGGTGCCGTGTTAGAA
GTCATTATGGCTGGTAAAGGTGCTGCTGTCGCGGAAGGAACACAGGCAATAGCAACAGGAGTAGGCATCTGTTGGGGGAA
AGATAAAAATGGAGACTTGATAGGCGGTTGGGCAGCTGAATATGTCGAATTTTTCCCGACCTGGATCGATGATGAAATCG
CTGAATCTCACGCAAAAATGTGGTTAAAAAAATCTCTGCAACATGAACTTGACCTGCGTTCTGTAAGCAAACACAGTGAA
TTTCAATATTTCCATAACTATATCAATATCAAAAAGAAATTCGGATTTTGCTTAACAGCTCTTGGCTTCTTAAATTTTGA
AAATGCAGATCCAGTTGTTATCCAATAA

Upstream 100 bases:

>100_bases
CTATAGCGTTCGCGCAAACCTAGCTATTTAGTAGGTTTGCACGAATACCTAGGGGGGCTTTGTAGTTAAATACCTTAATA
ACCCCAAAAAAGGAGGCATT

Downstream 100 bases:

>100_bases
GCAAGGGGGATTTTATGTTCTTGAAAAAACGCTCCTCTTCAGGAATTTTAGGGACATTGTCTCTTACTGGAGTTGTGATC
AGCTCCATGGTTGGAGGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: PvlArgDC; Biodegradative arginine decarboxylase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNILPVDQCTKFFKHGAVLE
VIMAGKGAAVAEGTQAIATGVGICWGKDKNGDLIGGWAAEYVEFFPTWIDDEIAESHAKMWLKKSLQHELDLRSVSKHSE
FQYFHNYINIKKKFGFCLTALGFLNFENADPVVIQ

Sequences:

>Translated_195_residues
MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNILPVDQCTKFFKHGAVLE
VIMAGKGAAVAEGTQAIATGVGICWGKDKNGDLIGGWAAEYVEFFPTWIDDEIAESHAKMWLKKSLQHELDLRSVSKHSE
FQYFHNYINIKKKFGFCLTALGFLNFENADPVVIQ
>Mature_194_residues
PYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNILPVDQCTKFFKHGAVLEV
IMAGKGAAVAEGTQAIATGVGICWGKDKNGDLIGGWAAEYVEFFPTWIDDEIAESHAKMWLKKSLQHELDLRSVSKHSEF
QYFHNYINIKKKFGFCLTALGFLNFENADPVVIQ

Specific function: Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response [H]

COG id: COG1945

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyruvoyl-dependent arginine decarboxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016104
- InterPro:   IPR016105
- InterPro:   IPR002724
- ProDom:   PD010449 [H]

Pfam domain/function: PF01862 PvlArgDC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 21707; Mature: 21576

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELF
CCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GNILPVDQCTKFFKHGAVLEVIMAGKGAAVAEGTQAIATGVGICWGKDKNGDLIGGWAAE
CCCCCHHHHHHHHHCCHHEEHEECCCCCCHHCCHHHHHHHCEEEECCCCCCCEECHHHHH
YVEFFPTWIDDEIAESHAKMWLKKSLQHELDLRSVSKHSEFQYFHNYINIKKKFGFCLTA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFLNFENADPVVIQ
HHHHCCCCCCCEEEC
>Mature Secondary Structure 
PYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELF
CCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GNILPVDQCTKFFKHGAVLEVIMAGKGAAVAEGTQAIATGVGICWGKDKNGDLIGGWAAE
CCCCCHHHHHHHHHCCHHEEHEECCCCCCHHCCHHHHHHHCEEEECCCCCCCEECHHHHH
YVEFFPTWIDDEIAESHAKMWLKKSLQHELDLRSVSKHSEFQYFHNYINIKKKFGFCLTA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFLNFENADPVVIQ
HHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA