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The map label for this gene is dnaZ

Identifier: 15835228

GI number: 15835228

Start: 735400

End: 736797

Strand: Direct

Name: dnaZ

Synonym: TC0611

Alternate gene names: 15835228

Gene position: 735400-736797 (Clockwise)

Preceding gene: 15835227

Following gene: 15835229

Centisome position: 68.54

GC content: 41.63

Gene sequence:

>1398_bases
ATGACCTCTTATCAAGTTTCTTCAAGAAGACATCGTCCCAATACTTTTTCAGAGATTCTTGGACAAGATATGGTCGTGTC
CATACTCAAAAATTCTCTTCGACTCAATCGTTCCGCCCATGCCTATATATTTTCTGGAATTCGCGGAACTGGAAAAACAA
CATTAGCACGAGTATTTGCTAAAGCCTTAAATTGCCAGTCCCCAACAGAAAATCAAGAACCCTGCAACCAGTGTGCTATT
TGTAAAGAAATCTCTCTTGGCACCTCAATGGATGTCATGGAAATCGATGGAGCTTCTCATCGAGGAATCGAAGATATTCG
GCAAATTAATGAAACTGTCCTCTTTGTTCCTTCAAAATCCCGATATAAAATTTATATTATCGATGAAGTGCACATGCTGA
CCAAGGAAGCTTTTAATTCATTACTGAAGACATTAGAAGAACCTCCTGCACATGTAAAATTTTTCCTTGCTACTACAGAA
ATTGCAAAAATTCCTAATACCATATCCAGTCGCTGTCAAAAAATGCTCTTAAAACGTATTCCTGAAGAGACTATTATTGA
TAAACTGACAACCATCGCAAAATTAGGAAAAATAGAAGCTTCTCGAGAAGCTCTTCTTCCCATTGCCAAGGCCGCACAAG
GAAGCCTCCGCGATGCCGAGTCGCTTTATGACTATGTAGTAGGCCTTTTCCCTGAGTCATTCACCCCAGAAGACACAGCT
AAGGCTCTTGGGATTCTTTCCGATGACACGCTATACCAAATAGCAGAAGCCATCACCACCCAAAACTATGAACAAGCTCT
TTCCCCAGTCTCCGACGCTATGCATATGGGGGTGGCACCAGCTCACTTTCTTCAAGATCTGACATTGCTTTTCCGCAGCT
TACTTTTAAAACAGCATTCTCAAAAATTTGATTCTATAGCTGTTAAGTACTCTTCTGAAAGTTTACTAGAAATTCTTGAT
TTTCTGGGCGAGTCTGCTCGACATGTCAATCTTGCACTTTTTGAAAAAACATTTTTAGAAACAGTGATTATTCGCCTTCT
GCGAATCTATTCTCGCCCTACGCTTTCTCAACTTGTCTCGCAAATAAAACAACCCGCCCAATCTCCATTACGCCCAATCC
CTTCTTCCCCAGTGCTAGATCCTGGCCCCTCCCCCACCAAATCTATCGTTAAAGAGGAAGTAAAAGCATTACCACAACCA
GTAGAAGCCAAATTTTCTCAGGGGAGCTTACTAACCCCACCCCCTTCGCAGCCTAAGAAAGAAACCCTTAATCAAGAAGT
ATCTGCTCCTTCATCGAGCACCCCTTCCTGTTCTGAAGCTGCTGCTATTGATACGTTATTACAATTTGCTGTTGTAGAAT
TTTCTGGAGTTTTAACTAAGGAGCCGAAACATGGGTAG

Upstream 100 bases:

>100_bases
AGATTAATACAGGGGAAAATGCGTAAACTAGTCAGGAAAAGAGACTCGCGAAATCCACTCGCAGTTTCCTTTATCAGGAT
AGCATACGGTTCTTTTAGTT

Downstream 100 bases:

>100_bases
CGGTTACGCTAAAAAGAAAAAAGAAGCCAAATTAATGGAACGCCAATTTATGGAAATGGAAGCCTCTCTCGAGCAAAAAC
GTTTCTCTGGAGAGGCTGGA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTSYQVSSRRHRPNTFSEILGQDMVVSILKNSLRLNRSAHAYIFSGIRGTGKTTLARVFAKALNCQSPTENQEPCNQCAI
CKEISLGTSMDVMEIDGASHRGIEDIRQINETVLFVPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPAHVKFFLATTE
IAKIPNTISSRCQKMLLKRIPEETIIDKLTTIAKLGKIEASREALLPIAKAAQGSLRDAESLYDYVVGLFPESFTPEDTA
KALGILSDDTLYQIAEAITTQNYEQALSPVSDAMHMGVAPAHFLQDLTLLFRSLLLKQHSQKFDSIAVKYSSESLLEILD
FLGESARHVNLALFEKTFLETVIIRLLRIYSRPTLSQLVSQIKQPAQSPLRPIPSSPVLDPGPSPTKSIVKEEVKALPQP
VEAKFSQGSLLTPPPSQPKKETLNQEVSAPSSSTPSCSEAAAIDTLLQFAVVEFSGVLTKEPKHG

Sequences:

>Translated_465_residues
MTSYQVSSRRHRPNTFSEILGQDMVVSILKNSLRLNRSAHAYIFSGIRGTGKTTLARVFAKALNCQSPTENQEPCNQCAI
CKEISLGTSMDVMEIDGASHRGIEDIRQINETVLFVPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPAHVKFFLATTE
IAKIPNTISSRCQKMLLKRIPEETIIDKLTTIAKLGKIEASREALLPIAKAAQGSLRDAESLYDYVVGLFPESFTPEDTA
KALGILSDDTLYQIAEAITTQNYEQALSPVSDAMHMGVAPAHFLQDLTLLFRSLLLKQHSQKFDSIAVKYSSESLLEILD
FLGESARHVNLALFEKTFLETVIIRLLRIYSRPTLSQLVSQIKQPAQSPLRPIPSSPVLDPGPSPTKSIVKEEVKALPQP
VEAKFSQGSLLTPPPSQPKKETLNQEVSAPSSSTPSCSEAAAIDTLLQFAVVEFSGVLTKEPKHG
>Mature_464_residues
TSYQVSSRRHRPNTFSEILGQDMVVSILKNSLRLNRSAHAYIFSGIRGTGKTTLARVFAKALNCQSPTENQEPCNQCAIC
KEISLGTSMDVMEIDGASHRGIEDIRQINETVLFVPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPAHVKFFLATTEI
AKIPNTISSRCQKMLLKRIPEETIIDKLTTIAKLGKIEASREALLPIAKAAQGSLRDAESLYDYVVGLFPESFTPEDTAK
ALGILSDDTLYQIAEAITTQNYEQALSPVSDAMHMGVAPAHFLQDLTLLFRSLLLKQHSQKFDSIAVKYSSESLLEILDF
LGESARHVNLALFEKTFLETVIIRLLRIYSRPTLSQLVSQIKQPAQSPLRPIPSSPVLDPGPSPTKSIVKEEVKALPQPV
EAKFSQGSLLTPPPSQPKKETLNQEVSAPSSSTPSCSEAAAIDTLLQFAVVEFSGVLTKEPKHG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=288, Percent_Identity=23.2638888888889, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI31881687, Length=288, Percent_Identity=23.2638888888889, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI31563534, Length=309, Percent_Identity=21.3592233009709, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1786676, Length=298, Percent_Identity=41.9463087248322, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1787341, Length=165, Percent_Identity=30.9090909090909, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17554730, Length=223, Percent_Identity=26.457399103139, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71986063, Length=260, Percent_Identity=25.7692307692308, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322528, Length=301, Percent_Identity=22.9235880398671, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324478, Length=253, Percent_Identity=23.3201581027668, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647857, Length=297, Percent_Identity=23.5690235690236, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 51306; Mature: 51174

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYQVSSRRHRPNTFSEILGQDMVVSILKNSLRLNRSAHAYIFSGIRGTGKTTLARVFA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCHHHHHHHHH
KALNCQSPTENQEPCNQCAICKEISLGTSMDVMEIDGASHRGIEDIRQINETVLFVPSKS
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCEEEEECCC
RYKIYIIDEVHMLTKEAFNSLLKTLEEPPAHVKFFLATTEIAKIPNTISSRCQKMLLKRI
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHC
PEETIIDKLTTIAKLGKIEASREALLPIAKAAQGSLRDAESLYDYVVGLFPESFTPEDTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHH
KALGILSDDTLYQIAEAITTQNYEQALSPVSDAMHMGVAPAHFLQDLTLLFRSLLLKQHS
HHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QKFDSIAVKYSSESLLEILDFLGESARHVNLALFEKTFLETVIIRLLRIYSRPTLSQLVS
HHHHHEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QIKQPAQSPLRPIPSSPVLDPGPSPTKSIVKEEVKALPQPVEAKFSQGSLLTPPPSQPKK
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHH
ETLNQEVSAPSSSTPSCSEAAAIDTLLQFAVVEFSGVLTKEPKHG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSYQVSSRRHRPNTFSEILGQDMVVSILKNSLRLNRSAHAYIFSGIRGTGKTTLARVFA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCHHHHHHHHH
KALNCQSPTENQEPCNQCAICKEISLGTSMDVMEIDGASHRGIEDIRQINETVLFVPSKS
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCEEEEECCC
RYKIYIIDEVHMLTKEAFNSLLKTLEEPPAHVKFFLATTEIAKIPNTISSRCQKMLLKRI
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHC
PEETIIDKLTTIAKLGKIEASREALLPIAKAAQGSLRDAESLYDYVVGLFPESFTPEDTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHH
KALGILSDDTLYQIAEAITTQNYEQALSPVSDAMHMGVAPAHFLQDLTLLFRSLLLKQHS
HHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QKFDSIAVKYSSESLLEILDFLGESARHVNLALFEKTFLETVIIRLLRIYSRPTLSQLVS
HHHHHEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QIKQPAQSPLRPIPSSPVLDPGPSPTKSIVKEEVKALPQPVEAKFSQGSLLTPPPSQPKK
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHH
ETLNQEVSAPSSSTPSCSEAAAIDTLLQFAVVEFSGVLTKEPKHG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]