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The map label for this gene is nusG

Identifier: 15835211

GI number: 15835211

Start: 711395

End: 711943

Strand: Reverse

Name: nusG

Synonym: TC0594

Alternate gene names: 15835211

Gene position: 711943-711395 (Counterclockwise)

Preceding gene: 15835212

Following gene: 15835210

Centisome position: 66.35

GC content: 38.07

Gene sequence:

>549_bases
ATGTTTAAGTGGTATGTCGTCCAAGTTTTTACGGCTCAAGAGAAGAAAGTAAAAAAGTCTTTAGAGGATTTTAAAGAAGC
CTCAGGGATGTCTGATTTTATTCAGCAGATTATCCTCCCTTCCGAGAATGTCATGGAAGTAAAAAAAGGCGAACATAAGA
TTGTTGAAAAGTATATTTGGCCGGGCTACCTCTTAGTTAAGATGCATTTAACAGATGAATCTTGGTCCTATGTAAAGAAA
ACTCAGGGTGTAGTTGAATTTCTTGGAGGAGGGGCTCCTGTAGCTTTGTCCGAAGAAGAAGTAAAAAATATTCTAGCAGA
TCTAGAAGAGAAGAAATCTGGAGTTGTTCAGAAACATAAATTTGAAGTGGGATCCCAAGTTAAAATTAATGATGGTGTTT
TTGTTAATTTTGTTGGGGTTGTTTCAGAGGTATTTCATGACAAAGGACGGCTTAGTGTCATGGTTTCTATCTTTGGAAGA
GAGACTCGTGTTGATGATTTAGAGTTCTGGCAGGTAGAAGAAGTCGCTCCAGGACAAGAAAGTGAGTGA

Upstream 100 bases:

>100_bases
TATTTTTGGCTTTGGCTTTTCCATTTATTGTGTGGATTTAGTTCTTCGAAAGTCTCTTTCATTGTTAGGTAAAGTAACAA
GCTTTTTCTTTGGTTGATTC

Downstream 100 bases:

>100_bases
GAATAAGGAATTCTGTGTATTCTTATTCTCCTTGTTCTTATAATTTAACTTTTTCGTTTTTCCCCCTCGTTTTTGAGAGG
AATACTAAGGTAGAGTAGGG

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MFKWYVVQVFTAQEKKVKKSLEDFKEASGMSDFIQQIILPSENVMEVKKGEHKIVEKYIWPGYLLVKMHLTDESWSYVKK
TQGVVEFLGGGAPVALSEEEVKNILADLEEKKSGVVQKHKFEVGSQVKINDGVFVNFVGVVSEVFHDKGRLSVMVSIFGR
ETRVDDLEFWQVEEVAPGQESE

Sequences:

>Translated_182_residues
MFKWYVVQVFTAQEKKVKKSLEDFKEASGMSDFIQQIILPSENVMEVKKGEHKIVEKYIWPGYLLVKMHLTDESWSYVKK
TQGVVEFLGGGAPVALSEEEVKNILADLEEKKSGVVQKHKFEVGSQVKINDGVFVNFVGVVSEVFHDKGRLSVMVSIFGR
ETRVDDLEFWQVEEVAPGQESE
>Mature_182_residues
MFKWYVVQVFTAQEKKVKKSLEDFKEASGMSDFIQQIILPSENVMEVKKGEHKIVEKYIWPGYLLVKMHLTDESWSYVKK
TQGVVEFLGGGAPVALSEEEVKNILADLEEKKSGVVQKHKFEVGSQVKINDGVFVNFVGVVSEVFHDKGRLSVMVSIFGR
ETRVDDLEFWQVEEVAPGQESE

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=175, Percent_Identity=40, Blast_Score=131, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_CHLMU (Q9PK75)

Other databases:

- EMBL:   AE002160
- PIR:   D81685
- RefSeq:   NP_296970.1
- ProteinModelPortal:   Q9PK75
- SMR:   Q9PK75
- GeneID:   1245953
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0594
- TIGR:   TC_0594
- HOGENOM:   HBG751162
- OMA:   VASGCEK
- ProtClustDB:   PRK05609
- BioCyc:   CMUR243161:TC_0594-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20718; Mature: 20718

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKWYVVQVFTAQEKKVKKSLEDFKEASGMSDFIQQIILPSENVMEVKKGEHKIVEKYIW
CCEEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHCC
PGYLLVKMHLTDESWSYVKKTQGVVEFLGGGAPVALSEEEVKNILADLEEKKSGVVQKHK
CCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHH
FEVGSQVKINDGVFVNFVGVVSEVFHDKGRLSVMVSIFGRETRVDDLEFWQVEEVAPGQE
HCCCCEEEECCCEEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHEEECCCCCCCC
SE
CC
>Mature Secondary Structure
MFKWYVVQVFTAQEKKVKKSLEDFKEASGMSDFIQQIILPSENVMEVKKGEHKIVEKYIW
CCEEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHCC
PGYLLVKMHLTDESWSYVKKTQGVVEFLGGGAPVALSEEEVKNILADLEEKKSGVVQKHK
CCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHH
FEVGSQVKINDGVFVNFVGVVSEVFHDKGRLSVMVSIFGRETRVDDLEFWQVEEVAPGQE
HCCCCEEEECCCEEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHEEECCCCCCCC
SE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935