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The map label for this gene is rpoC

Identifier: 15835205

GI number: 15835205

Start: 700860

End: 705050

Strand: Reverse

Name: rpoC

Synonym: TC0588

Alternate gene names: 15835205

Gene position: 705050-700860 (Counterclockwise)

Preceding gene: 15835206

Following gene: 15835204

Centisome position: 65.71

GC content: 42.02

Gene sequence:

>4191_bases
ATGTTCAAAGAAGGTTCTCGAGACGATGCAGCCCTAGCAAAAGAAGGGTTGTTTGATAAGTTAGAAATTGGGATTGCTTC
AGATGTGACTATTCGCGACAAGTGGTCTTGTGGCGAAATTAAGAAACCTGAGACGATCAATTATCGCACATTCAAGCCTG
AAAAAGGCGGATTGTTTTGTGAGAAGATTTTCGGTCCTACTAAGGACTGGGAATGTTACTGCGGTAAATACAAGAAGATT
AAGCACAAAGGTATTGTGTGTGATCGTTGCGGAGTGGAAGTCACGCTGTCTAAGGTGCGACGAGAAAGAATGGCTCATAT
TGAATTAGCTGTTCCTATTGTTCACATTTGGTTTTTCAAAACTACTCCATCTAGAATTGGTAATGTTTTGGGAATGACAG
CTTCGGATTTGGAGCGTGTAATTTACTACGAAGAATACGTTGTCATTGATCCAGGTAATACTGATCTTGTGAAAAAACAA
CTTCTGAATGATGCAAAATATCGAGAAGTTGTTGAGAAATGGGGTAAAGATGCTTTTGTCGCCAAAATGGGGGGAGAAGC
TGTTTATGATCTTCTTAAATCCGAGGATTTAGAAAGCCTCCTTGGTGAGCTTAAAGATCGTTTGAGAAAAACAAAATCCC
AGCAAGCAAGAATGAAGCTTGCTAAGCGGTTGAAGATTGTAGAAGGGTTTGTATCTTCCTCTAACCGTCCAGAATGGATG
GTCTTGAAGAACATCCCTGTTGTTCCACCAGATCTTCGTCCTTTAGTTCCATTGGATGGAGGGCGTTTTGCTACTTCAGA
TCTGAACGATTTATATCGTAGGGTTATTAATCGAAATAATCGTTTGAAAGCTATCTTGCGCTTGAAGACTCCTGAGGTAA
TTGTTCGCAATGAGAAACGGATGTTACAGGAAGCTGTGGATGCTCTGTTTGATAATGGACGTCATGGACATCCTGTTATG
GGAGCAGGAAATAGACCCCTTAAGTCTCTATCAGAGATGTTAAAAGGGAAAAATGGTCGTTTCCGACAAAACTTATTAGG
TAAACGAGTAGACTACTCTGGCCGTTCTGTTATTATTGTTGGTCCCGAGTTGAAGTTTAATCAATGTGGTTTGCCCAAAG
AAATGGCGTTAGAGTTGTTCGAGCCATTCATTATCAAGCGACTAAAAGATCAGGGTAGTGTTTATACTATCCGTTCAGCA
AAGAAAATGATTCAACGAGGCGCACCAGAGGTTTGGGACGTTCTTGAGGAAATCATTAAAGGACACCCAGTCTTATTGAA
CCGAGCTCCTACTTTGCACCGATTGGGAATACAGGCTTTTGAGCCAGTGTTGATTGAAGGGAAAGCGATTCGGGTTCACC
CATTAGTGTGTGCAGCGTTTAACGCCGATTTCGATGGAGACCAAATGGCGGTTCACGTGCCTCTTTCTATTGAAGCTCAG
TTAGAGGCGAAGGTGTTAATGATGGCTCCTGATAACATTTTCTTGCCATCTTCTGGAAAACCTGTTGCCACACCTTCTAA
GGATATGACATTGGGCATCTATTATTTGATGGCTGATCCAACGTATTTTCCTGAAGAACACGGAGGGAAAACTAAAGTAT
TTAAAGATGAAGTAGAAGTACTTCGTGCTTTGAATGCTGGAGGTTTTATCCTTAAGGATGAGATATGTGGTTCTCGTCGG
GATGAAACTGGACGAGGGATTCATATTCATGAAGCCATTAAAGTTCGAATTGATGGTCAAATTATTGAGACCACTCCTGG
CCGCGTATTTTTCAACACAATCGTTCCTAAAGAACTTGGCTTCCAAAACTATAGTATGCCAAGTAAACGTATCAGTGAGC
TAATCTTGCAATGCTATAAGAAAGTTGGTTTAGAAGCTACTGTACGCTTTTTGGATGATTTGAAAGAGCTAGGTTTCGTG
CAATCTACGAAAGCTGCAATTTCTATGGGATTGAAGGATGTTCGAATTCCTGAAATTAAGAAAGAGATTTTGAAAGACGC
TTACGATAAGGTTGCTGTCGTTAAGAAACAATATGAAGACGGTATTATTACCGATGGGGAGCGGCATTCCAAGACAATTA
GTATCTGGACTGAAGTTTCCGATCTTTTATCTAATGCGTTGTATGCTGAGATCAAAAAGCAAACCAATAGCAAACATAAT
CCGCTGTTCTTAATGATTGATTCTGGAGCTAGAGGAAACAAATCTCAGTTGAAACAGCTTGGAGCTTTGCGGGGATTGAT
GGCTAAACCTAACGGAGCCATTATTGAATCTCCAATTACTTCTAACTTCCGAGAAGGATTGACAGTGCTTGAGTACTCTA
TTTCTTCTCACGGAGCTAGAAAAGGATTAGCAGACACAGCGCTTAAAACTGCGGATTCCGGATATTTAACCCGTCGTTTG
GTGGACGTTGCTCAGGATGTTATCATTACAGAAAAAGATTGTGGTACATTGAATCATATTGAGGTGTCGACAATCCGTCA
GGGGTCTGAAGAATTACTGCCTTTGAAAGACCGTATTTATGGACGTACAGTTTCTGAAAATGTCTATCAGCCAGGAGATA
AAAGTAACGTTTTAGCCTATGCTGGGGATGTATTAACTTCTTCCCAAGCTGAGGCTATTGATGATGCAGGTATTGATAGC
GTAAAAATCCGATCTACGCTTACTTGTGAAAGCCGGCGAGGAGTTTGTGCCAAGTGTTATGGTTTGAACCTTGCTAATGG
CCGGCTGATTGGATTAGGAGAAGCTGTTGGTATTATTGCTGCTCAATCCATTGGGGAACCTGGAACTCAGTTAACAATGA
GAACGTTCCACCTTGGGGGGATTGCTGCGACATCCTCAACTCCAGAAATCGTTGCCGAGTGTGATGGAATTCTTGTTTAC
TTAGACTTACGCTTTGTTGTAGACCAAGAAGGTAATAATCTTGTTCTGAATAAGATGGGAGCTCTTCACTTGGTCCGTGA
CGAAGGACGAAGTTTGAGTGAATACAAGAAGCTTTTGAGTACGAAGTCCATCGAAAGCTTAGCGACATTCCCAGTAGAAT
TGGGAGCTAAGATTTTGGTTGATGACGGTGCAGCTGTCACGGCCGGACAAAGAATTGCTGAAGTTGAGCTCCACAATATC
CCAATTATCTGTGATAAGCCAGGATTCGTTCACTATGAAGATTTAGTGGAAGGAGTTTCCACAGAGAAAGTCACGAATAA
GAACACGGGTCTTGTCGAATTAATTGTGAAACAACACAGGGGAGAATTGCATCCTCAGATTGCTATATATGCTGACGCCA
ATATGCAGGAATTGGTTGGTACATATGCCATTCCTTCTGGGGCTATTATCTCTGTTGAAGAGGGGCAACGTATTGCTCCA
GGAATGTTGTTAGCGAGATTGCCTCGAGGAGCAATTAAAACGAAGGATATTACTGGTGGTTTGCCTAGGGTTGCAGAGTT
AGTAGAAGCTCGTAAGCCTGAAGATGCCGCGGATATTGCTAAGATTGATGGGGTTGTAGACTTCAAAGGTATCCAGAAGA
ATAAGCGTATTCTTGTTGTGCGTGATGAAGTTACGGGAATGGAAGAAGAGCATCTGATTTCTTTGACCAAACACTTGATC
GTGCAACGTGGAGATAGCGTAATCAAAGGTCAGCAGTTAACGGACGGTTTAGTCGTTCCTCATGAAATTCTTGAAATTTG
TGGGGTTCGTGAATTGCAGAAATATTTGGTTAATGAGGTTCAAGAAGTATACCGACTGCAAGGTGTGGACATTAATGACA
AACACATTGAAATTATTGTTCGACAGATGTTGCAGAAAGTGCGTATTACTGATCCAGGTGATACAACCTTGTTGTTCGGA
GAGGATGTCGATAAGAAAGAGTTTTATGAAGAAAACCGCCGTACGGAAGAGGATGGAGGGAAACCTGCTCAAGCTGTTCC
AGTGCTGCTTGGAATCACTAAAGCTTCTTTGGGAACGGAGTCCTTTATTTCCGCGGCCTCATTCCAGGACACAACTCGAG
TTTTAACAGATGCTGCTTGCAGTAGTAAGACAGATTATCTGCTAGGATTCAAAGAGAATGTGATTATGGGGCACATGATC
CCTGGTGGTACAGGATTTGATACGCATAAACGTATTAAGCAGCACCTCGAAAAAGAGCAAGAAGACTTGGTCTTTGACTT
CGATAGTGAGTTTGAGTCTGTAGCAGGCTAA

Upstream 100 bases:

>100_bases
TGAGTCGTTCAATGTTTTGATTAAAGAAATGCAAGGTCTAGGGCTCGATGTTCGCCCTATGGTAGTAGATGCTTAAAAAA
CACTTGTTGGAGATAAGTTA

Downstream 100 bases:

>100_bases
GGGTCTGCCTCAAAAACTTGAAAGGGGGGAGTAATATGATCACAACCCCCTTGAATAGTATCATTTTTTTTGGTAGGCTT
CGCATAAAGTCAAAAATTGA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1396; Mature: 1396

Protein sequence:

>1396_residues
MFKEGSRDDAALAKEGLFDKLEIGIASDVTIRDKWSCGEIKKPETINYRTFKPEKGGLFCEKIFGPTKDWECYCGKYKKI
KHKGIVCDRCGVEVTLSKVRRERMAHIELAVPIVHIWFFKTTPSRIGNVLGMTASDLERVIYYEEYVVIDPGNTDLVKKQ
LLNDAKYREVVEKWGKDAFVAKMGGEAVYDLLKSEDLESLLGELKDRLRKTKSQQARMKLAKRLKIVEGFVSSSNRPEWM
VLKNIPVVPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILRLKTPEVIVRNEKRMLQEAVDALFDNGRHGHPVM
GAGNRPLKSLSEMLKGKNGRFRQNLLGKRVDYSGRSVIIVGPELKFNQCGLPKEMALELFEPFIIKRLKDQGSVYTIRSA
KKMIQRGAPEVWDVLEEIIKGHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRVHPLVCAAFNADFDGDQMAVHVPLSIEAQ
LEAKVLMMAPDNIFLPSSGKPVATPSKDMTLGIYYLMADPTYFPEEHGGKTKVFKDEVEVLRALNAGGFILKDEICGSRR
DETGRGIHIHEAIKVRIDGQIIETTPGRVFFNTIVPKELGFQNYSMPSKRISELILQCYKKVGLEATVRFLDDLKELGFV
QSTKAAISMGLKDVRIPEIKKEILKDAYDKVAVVKKQYEDGIITDGERHSKTISIWTEVSDLLSNALYAEIKKQTNSKHN
PLFLMIDSGARGNKSQLKQLGALRGLMAKPNGAIIESPITSNFREGLTVLEYSISSHGARKGLADTALKTADSGYLTRRL
VDVAQDVIITEKDCGTLNHIEVSTIRQGSEELLPLKDRIYGRTVSENVYQPGDKSNVLAYAGDVLTSSQAEAIDDAGIDS
VKIRSTLTCESRRGVCAKCYGLNLANGRLIGLGEAVGIIAAQSIGEPGTQLTMRTFHLGGIAATSSTPEIVAECDGILVY
LDLRFVVDQEGNNLVLNKMGALHLVRDEGRSLSEYKKLLSTKSIESLATFPVELGAKILVDDGAAVTAGQRIAEVELHNI
PIICDKPGFVHYEDLVEGVSTEKVTNKNTGLVELIVKQHRGELHPQIAIYADANMQELVGTYAIPSGAIISVEEGQRIAP
GMLLARLPRGAIKTKDITGGLPRVAELVEARKPEDAADIAKIDGVVDFKGIQKNKRILVVRDEVTGMEEEHLISLTKHLI
VQRGDSVIKGQQLTDGLVVPHEILEICGVRELQKYLVNEVQEVYRLQGVDINDKHIEIIVRQMLQKVRITDPGDTTLLFG
EDVDKKEFYEENRRTEEDGGKPAQAVPVLLGITKASLGTESFISAASFQDTTRVLTDAACSSKTDYLLGFKENVIMGHMI
PGGTGFDTHKRIKQHLEKEQEDLVFDFDSEFESVAG

Sequences:

>Translated_1396_residues
MFKEGSRDDAALAKEGLFDKLEIGIASDVTIRDKWSCGEIKKPETINYRTFKPEKGGLFCEKIFGPTKDWECYCGKYKKI
KHKGIVCDRCGVEVTLSKVRRERMAHIELAVPIVHIWFFKTTPSRIGNVLGMTASDLERVIYYEEYVVIDPGNTDLVKKQ
LLNDAKYREVVEKWGKDAFVAKMGGEAVYDLLKSEDLESLLGELKDRLRKTKSQQARMKLAKRLKIVEGFVSSSNRPEWM
VLKNIPVVPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILRLKTPEVIVRNEKRMLQEAVDALFDNGRHGHPVM
GAGNRPLKSLSEMLKGKNGRFRQNLLGKRVDYSGRSVIIVGPELKFNQCGLPKEMALELFEPFIIKRLKDQGSVYTIRSA
KKMIQRGAPEVWDVLEEIIKGHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRVHPLVCAAFNADFDGDQMAVHVPLSIEAQ
LEAKVLMMAPDNIFLPSSGKPVATPSKDMTLGIYYLMADPTYFPEEHGGKTKVFKDEVEVLRALNAGGFILKDEICGSRR
DETGRGIHIHEAIKVRIDGQIIETTPGRVFFNTIVPKELGFQNYSMPSKRISELILQCYKKVGLEATVRFLDDLKELGFV
QSTKAAISMGLKDVRIPEIKKEILKDAYDKVAVVKKQYEDGIITDGERHSKTISIWTEVSDLLSNALYAEIKKQTNSKHN
PLFLMIDSGARGNKSQLKQLGALRGLMAKPNGAIIESPITSNFREGLTVLEYSISSHGARKGLADTALKTADSGYLTRRL
VDVAQDVIITEKDCGTLNHIEVSTIRQGSEELLPLKDRIYGRTVSENVYQPGDKSNVLAYAGDVLTSSQAEAIDDAGIDS
VKIRSTLTCESRRGVCAKCYGLNLANGRLIGLGEAVGIIAAQSIGEPGTQLTMRTFHLGGIAATSSTPEIVAECDGILVY
LDLRFVVDQEGNNLVLNKMGALHLVRDEGRSLSEYKKLLSTKSIESLATFPVELGAKILVDDGAAVTAGQRIAEVELHNI
PIICDKPGFVHYEDLVEGVSTEKVTNKNTGLVELIVKQHRGELHPQIAIYADANMQELVGTYAIPSGAIISVEEGQRIAP
GMLLARLPRGAIKTKDITGGLPRVAELVEARKPEDAADIAKIDGVVDFKGIQKNKRILVVRDEVTGMEEEHLISLTKHLI
VQRGDSVIKGQQLTDGLVVPHEILEICGVRELQKYLVNEVQEVYRLQGVDINDKHIEIIVRQMLQKVRITDPGDTTLLFG
EDVDKKEFYEENRRTEEDGGKPAQAVPVLLGITKASLGTESFISAASFQDTTRVLTDAACSSKTDYLLGFKENVIMGHMI
PGGTGFDTHKRIKQHLEKEQEDLVFDFDSEFESVAG
>Mature_1396_residues
MFKEGSRDDAALAKEGLFDKLEIGIASDVTIRDKWSCGEIKKPETINYRTFKPEKGGLFCEKIFGPTKDWECYCGKYKKI
KHKGIVCDRCGVEVTLSKVRRERMAHIELAVPIVHIWFFKTTPSRIGNVLGMTASDLERVIYYEEYVVIDPGNTDLVKKQ
LLNDAKYREVVEKWGKDAFVAKMGGEAVYDLLKSEDLESLLGELKDRLRKTKSQQARMKLAKRLKIVEGFVSSSNRPEWM
VLKNIPVVPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILRLKTPEVIVRNEKRMLQEAVDALFDNGRHGHPVM
GAGNRPLKSLSEMLKGKNGRFRQNLLGKRVDYSGRSVIIVGPELKFNQCGLPKEMALELFEPFIIKRLKDQGSVYTIRSA
KKMIQRGAPEVWDVLEEIIKGHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRVHPLVCAAFNADFDGDQMAVHVPLSIEAQ
LEAKVLMMAPDNIFLPSSGKPVATPSKDMTLGIYYLMADPTYFPEEHGGKTKVFKDEVEVLRALNAGGFILKDEICGSRR
DETGRGIHIHEAIKVRIDGQIIETTPGRVFFNTIVPKELGFQNYSMPSKRISELILQCYKKVGLEATVRFLDDLKELGFV
QSTKAAISMGLKDVRIPEIKKEILKDAYDKVAVVKKQYEDGIITDGERHSKTISIWTEVSDLLSNALYAEIKKQTNSKHN
PLFLMIDSGARGNKSQLKQLGALRGLMAKPNGAIIESPITSNFREGLTVLEYSISSHGARKGLADTALKTADSGYLTRRL
VDVAQDVIITEKDCGTLNHIEVSTIRQGSEELLPLKDRIYGRTVSENVYQPGDKSNVLAYAGDVLTSSQAEAIDDAGIDS
VKIRSTLTCESRRGVCAKCYGLNLANGRLIGLGEAVGIIAAQSIGEPGTQLTMRTFHLGGIAATSSTPEIVAECDGILVY
LDLRFVVDQEGNNLVLNKMGALHLVRDEGRSLSEYKKLLSTKSIESLATFPVELGAKILVDDGAAVTAGQRIAEVELHNI
PIICDKPGFVHYEDLVEGVSTEKVTNKNTGLVELIVKQHRGELHPQIAIYADANMQELVGTYAIPSGAIISVEEGQRIAP
GMLLARLPRGAIKTKDITGGLPRVAELVEARKPEDAADIAKIDGVVDFKGIQKNKRILVVRDEVTGMEEEHLISLTKHLI
VQRGDSVIKGQQLTDGLVVPHEILEICGVRELQKYLVNEVQEVYRLQGVDINDKHIEIIVRQMLQKVRITDPGDTTLLFG
EDVDKKEFYEENRRTEEDGGKPAQAVPVLLGITKASLGTESFISAASFQDTTRVLTDAACSSKTDYLLGFKENVIMGHMI
PGGTGFDTHKRIKQHLEKEQEDLVFDFDSEFESVAG

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=865, Percent_Identity=25.5491329479769, Blast_Score=190, Evalue=7e-48,
Organism=Homo sapiens, GI39725938, Length=324, Percent_Identity=29.320987654321, Blast_Score=124, Evalue=8e-28,
Organism=Homo sapiens, GI103471997, Length=236, Percent_Identity=31.7796610169492, Blast_Score=105, Evalue=3e-22,
Organism=Escherichia coli, GI2367335, Length=1391, Percent_Identity=49.8921639108555, Blast_Score=1340, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=1046, Percent_Identity=24.0917782026769, Blast_Score=181, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71987878, Length=645, Percent_Identity=25.7364341085271, Blast_Score=174, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6320061, Length=657, Percent_Identity=27.3972602739726, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=496, Percent_Identity=26.6129032258064, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281360912, Length=1053, Percent_Identity=25.1661918328585, Blast_Score=192, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17530899, Length=644, Percent_Identity=25.6211180124224, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI17647875, Length=328, Percent_Identity=25, Blast_Score=99, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_CHLMU (Q9PK79)

Other databases:

- EMBL:   AE002160
- PIR:   F81686
- RefSeq:   NP_296964.1
- ProteinModelPortal:   Q9PK79
- GeneID:   1245947
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0588
- TIGR:   TC_0588
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q9PK79
- ProtClustDB:   PRK00566
- BioCyc:   CMUR243161:TC_0588-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 154901; Mature: 154901

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKEGSRDDAALAKEGLFDKLEIGIASDVTIRDKWSCGEIKKPETINYRTFKPEKGGLFC
CCCCCCCCHHHHHHHCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCEEH
EKIFGPTKDWECYCGKYKKIKHKGIVCDRCGVEVTLSKVRRERMAHIELAVPIVHIWFFK
HHHCCCCCCCHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEE
TTPSRIGNVLGMTASDLERVIYYEEYVVIDPGNTDLVKKQLLNDAKYREVVEKWGKDAFV
CCHHHHHHHHCCCHHHHHHHEEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCEEE
AKMGGEAVYDLLKSEDLESLLGELKDRLRKTKSQQARMKLAKRLKIVEGFVSSSNRPEWM
ECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VLKNIPVVPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILRLKTPEVIVRNEKR
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHEECCHHH
MLQEAVDALFDNGRHGHPVMGAGNRPLKSLSEMLKGKNGRFRQNLLGKRVDYSGRSVIIV
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEE
GPELKFNQCGLPKEMALELFEPFIIKRLKDQGSVYTIRSAKKMIQRGAPEVWDVLEEIIK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHC
GHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRVHPLVCAAFNADFDGDQMAVHVPLSIEAQ
CCCEEEECCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECEEEEEE
LEAKVLMMAPDNIFLPSSGKPVATPSKDMTLGIYYLMADPTYFPEEHGGKTKVFKDEVEV
ECEEEEEECCCCEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHH
LRALNAGGFILKDEICGSRRDETGRGIHIHEAIKVRIDGQIIETTPGRVFFNTIVPKELG
HHHHCCCCEEEEHHHCCCCCCCCCCCEEEEEEEEEEECCEEEECCCCEEEEEECCCHHHC
FQNYSMPSKRISELILQCYKKVGLEATVRFLDDLKELGFVQSTKAAISMGLKDVRIPEIK
CCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHH
KEILKDAYDKVAVVKKQYEDGIITDGERHSKTISIWTEVSDLLSNALYAEIKKQTNSKHN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
PLFLMIDSGARGNKSQLKQLGALRGLMAKPNGAIIESPITSNFREGLTVLEYSISSHGAR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCEEEEEEHHCCCCC
KGLADTALKTADSGYLTRRLVDVAQDVIITEKDCGTLNHIEVSTIRQGSEELLPLKDRIY
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHCCCHHCCCHHHHHC
GRTVSENVYQPGDKSNVLAYAGDVLTSSQAEAIDDAGIDSVKIRSTLTCESRRGVCAKCY
CCCHHCCCCCCCCCCCEEEEECCHHCCCCHHHHHHCCCCCEEEEEEEEECCCCCCEEEEE
GLNLANGRLIGLGEAVGIIAAQSIGEPGTQLTMRTFHLGGIAATSSTPEIVAECDGILVY
CCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCEEECCCCCHHHHCCCCEEEE
LDLRFVVDQEGNNLVLNKMGALHLVRDEGRSLSEYKKLLSTKSIESLATFPVELGAKILV
EEEEEEEECCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCEEEE
DDGAAVTAGQRIAEVELHNIPIICDKPGFVHYEDLVEGVSTEKVTNKNTGLVELIVKQHR
ECCCEEECCCEEEEEEECCCCEEECCCCCEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
GELHPQIAIYADANMQELVGTYAIPSGAIISVEEGQRIAPGMLLARLPRGAIKTKDITGG
CCCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCC
LPRVAELVEARKPEDAADIAKIDGVVDFKGIQKNKRILVVRDEVTGMEEEHLISLTKHLI
CHHHHHHHHHCCCCCHHHHHHHCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
VQRGDSVIKGQQLTDGLVVPHEILEICGVRELQKYLVNEVQEVYRLQGVDINDKHIEIIV
HHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RQMLQKVRITDPGDTTLLFGEDVDKKEFYEENRRTEEDGGKPAQAVPVLLGITKASLGTE
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHEEEHHHHCCHH
SFISAASFQDTTRVLTDAACSSKTDYLLGFKENVIMGHMIPGGTGFDTHKRIKQHLEKEQ
HHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHH
EDLVFDFDSEFESVAG
HCEEEECCHHHHHHCC
>Mature Secondary Structure
MFKEGSRDDAALAKEGLFDKLEIGIASDVTIRDKWSCGEIKKPETINYRTFKPEKGGLFC
CCCCCCCCHHHHHHHCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCEEH
EKIFGPTKDWECYCGKYKKIKHKGIVCDRCGVEVTLSKVRRERMAHIELAVPIVHIWFFK
HHHCCCCCCCHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEE
TTPSRIGNVLGMTASDLERVIYYEEYVVIDPGNTDLVKKQLLNDAKYREVVEKWGKDAFV
CCHHHHHHHHCCCHHHHHHHEEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCEEE
AKMGGEAVYDLLKSEDLESLLGELKDRLRKTKSQQARMKLAKRLKIVEGFVSSSNRPEWM
ECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VLKNIPVVPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILRLKTPEVIVRNEKR
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHEECCHHH
MLQEAVDALFDNGRHGHPVMGAGNRPLKSLSEMLKGKNGRFRQNLLGKRVDYSGRSVIIV
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEE
GPELKFNQCGLPKEMALELFEPFIIKRLKDQGSVYTIRSAKKMIQRGAPEVWDVLEEIIK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHC
GHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRVHPLVCAAFNADFDGDQMAVHVPLSIEAQ
CCCEEEECCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECEEEEEE
LEAKVLMMAPDNIFLPSSGKPVATPSKDMTLGIYYLMADPTYFPEEHGGKTKVFKDEVEV
ECEEEEEECCCCEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHH
LRALNAGGFILKDEICGSRRDETGRGIHIHEAIKVRIDGQIIETTPGRVFFNTIVPKELG
HHHHCCCCEEEEHHHCCCCCCCCCCCEEEEEEEEEEECCEEEECCCCEEEEEECCCHHHC
FQNYSMPSKRISELILQCYKKVGLEATVRFLDDLKELGFVQSTKAAISMGLKDVRIPEIK
CCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHH
KEILKDAYDKVAVVKKQYEDGIITDGERHSKTISIWTEVSDLLSNALYAEIKKQTNSKHN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
PLFLMIDSGARGNKSQLKQLGALRGLMAKPNGAIIESPITSNFREGLTVLEYSISSHGAR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCEEEEEEHHCCCCC
KGLADTALKTADSGYLTRRLVDVAQDVIITEKDCGTLNHIEVSTIRQGSEELLPLKDRIY
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHCCCHHCCCHHHHHC
GRTVSENVYQPGDKSNVLAYAGDVLTSSQAEAIDDAGIDSVKIRSTLTCESRRGVCAKCY
CCCHHCCCCCCCCCCCEEEEECCHHCCCCHHHHHHCCCCCEEEEEEEEECCCCCCEEEEE
GLNLANGRLIGLGEAVGIIAAQSIGEPGTQLTMRTFHLGGIAATSSTPEIVAECDGILVY
CCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCEEECCCCCHHHHCCCCEEEE
LDLRFVVDQEGNNLVLNKMGALHLVRDEGRSLSEYKKLLSTKSIESLATFPVELGAKILV
EEEEEEEECCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCEEEE
DDGAAVTAGQRIAEVELHNIPIICDKPGFVHYEDLVEGVSTEKVTNKNTGLVELIVKQHR
ECCCEEECCCEEEEEEECCCCEEECCCCCEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
GELHPQIAIYADANMQELVGTYAIPSGAIISVEEGQRIAPGMLLARLPRGAIKTKDITGG
CCCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCC
LPRVAELVEARKPEDAADIAKIDGVVDFKGIQKNKRILVVRDEVTGMEEEHLISLTKHLI
CHHHHHHHHHCCCCCHHHHHHHCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
VQRGDSVIKGQQLTDGLVVPHEILEICGVRELQKYLVNEVQEVYRLQGVDINDKHIEIIV
HHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RQMLQKVRITDPGDTTLLFGEDVDKKEFYEENRRTEEDGGKPAQAVPVLLGITKASLGTE
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHEEEHHHHCCHH
SFISAASFQDTTRVLTDAACSSKTDYLLGFKENVIMGHMIPGGTGFDTHKRIKQHLEKEQ
HHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHH
EDLVFDFDSEFESVAG
HCEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935; 2211507