Click here to switch to the map view.

The map label for this gene is radA

Identifier: 15835188

GI number: 15835188

Start: 681305

End: 682789

Strand: Direct

Name: radA

Synonym: TC0571

Alternate gene names: 15835188

Gene position: 681305-682789 (Clockwise)

Preceding gene: 15835187

Following gene: 15835189

Centisome position: 63.5

GC content: 39.33

Gene sequence:

>1485_bases
ATGGCACTCCTGGATACCATGTACAAGTCTTCGTTAATGAAAAACTTTGGGGAGAGGGCTTTGCTGGATCAAAAAAGGAA
GCAGAAAAACTTGCAGCTAAACAGGCGTTATCAACACATGACGACAACAAAAATTAAAACACAATGGGCATGTTCAGAAT
GCGGCTCCTATTCTCCAAAATGGTTAGGACAATGCCCTGGATGCTTTCAATGGAATACTTTAGTTGAAGAAATACATTCT
TCTAAACTGAAAACCTCTTCTTATCCTCTCAGCTCTACAACTCCAGTTCCTCTTAACACTGTAAAATTTCAAGAAGAGAT
AAGAATTTCCACTCGTTCCAAAGGATGGAATCGCCTTCTTGGAGGGGGAACTGTATGTGGTAGTCTTACTTTACTAGGAG
GAGAACCTGGAATAGGAAAATCCACCTTATTACTTCAGATCTCTTCGCAATTTGCTGAGCAAGGCTATAAAGTATTGTAT
GTTTGTGGAGAAGAGTCTGTATCCCAAACTTCATTACGAGCACAACGCCTACAAATCTCTAGCAGCAATATTTTTCTATT
TCCAGAAACAAACCTTGAAGATATCAAGCAACAGATCTCCGATCTTGCTCCTGATATCCTAATCATTGATTCTATTCAGA
TTATTTTTTCCCCATCACTAAGCTCTGCTCCAGGATCAGTTGCTCAAGTTCGAGAAACTACAGCAGAACTCATGCATATT
GCAAAACAAAAACAAATTACGACTTTTATTATTGGGCATGTTACTAAATCAGGGGAAATCGCAGGACCACGTATTCTTGA
ACATTTAGTAGATACCGTCCTTTATTTTGAAGGCAATGCGCACACCAATTATCGCATGATCCGCTCTGTCAAAAATCGTT
TTGGCCCAACAAATGAGTTATTAATTTTATCTATGCAAACGGATGGGCTGCATGAAGTGGAAAATCCTTCAGGGTTCTTT
TTACAAGAAAAAGTTGTGGAAACAACAGGCTCGACAATTATCCCTATTGTAGAAGGATCTGAAACGCTTCTTGTAGAAGT
GCAAGCTCTAGTTTCTTCTTCTCCTTTCTCTAATCCAGTACGGAAAACTTCAGGATTTGATCCTAATCGGTTTTCTTTAC
TCTTAGCTGTTTTAGAAAAAAGAGCGAATGTCAAGTTATACACGTCTGATGTCTTTCTTTCGATAGCCGGTGGTTTAAAA
ATTACCCAACCTTCTGCAGATTTGGGAGCGGTTCTATCAGTTGTCTCCTCTCTATATAATCGCTACCTACCCAAGAATTA
TACCTACACTGGGGAAATTGGACTGGGCGGGGAGATTCGTCACGTCACACATATAGAGCATCGCATAAAAGAGAGCATTA
TCATGGGATTTAAGGGTATCGTCATGCCCTCTGGGCAAATAAAAGGCTTACCTAAAGAATATTTGGATCAAATTGATATT
ATTGGAGTAAAAACAATTAAAGATGCTGTCCGCCTACTACAATGA

Upstream 100 bases:

>100_bases
CCTCTAATGCTAGTTAATCCTAAAAATCGCTTACAACAATTCACTCAGCAGACATTAAAGGTTCTTCCTACATATATCGC
TCTTCCTTGGTCATCCGAAG

Downstream 100 bases:

>100_bases
CCCTTTTCTATCCGATTTTTGTTTAGGGAAGATCCCTTTACGTTTAGCATCTCGGAAGTCTCCTTTAGCCGTTCTACAAG
CCCATGAATGCCTAAGAAGA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MALLDTMYKSSLMKNFGERALLDQKRKQKNLQLNRRYQHMTTTKIKTQWACSECGSYSPKWLGQCPGCFQWNTLVEEIHS
SKLKTSSYPLSSTTPVPLNTVKFQEEIRISTRSKGWNRLLGGGTVCGSLTLLGGEPGIGKSTLLLQISSQFAEQGYKVLY
VCGEESVSQTSLRAQRLQISSSNIFLFPETNLEDIKQQISDLAPDILIIDSIQIIFSPSLSSAPGSVAQVRETTAELMHI
AKQKQITTFIIGHVTKSGEIAGPRILEHLVDTVLYFEGNAHTNYRMIRSVKNRFGPTNELLILSMQTDGLHEVENPSGFF
LQEKVVETTGSTIIPIVEGSETLLVEVQALVSSSPFSNPVRKTSGFDPNRFSLLLAVLEKRANVKLYTSDVFLSIAGGLK
ITQPSADLGAVLSVVSSLYNRYLPKNYTYTGEIGLGGEIRHVTHIEHRIKESIIMGFKGIVMPSGQIKGLPKEYLDQIDI
IGVKTIKDAVRLLQ

Sequences:

>Translated_494_residues
MALLDTMYKSSLMKNFGERALLDQKRKQKNLQLNRRYQHMTTTKIKTQWACSECGSYSPKWLGQCPGCFQWNTLVEEIHS
SKLKTSSYPLSSTTPVPLNTVKFQEEIRISTRSKGWNRLLGGGTVCGSLTLLGGEPGIGKSTLLLQISSQFAEQGYKVLY
VCGEESVSQTSLRAQRLQISSSNIFLFPETNLEDIKQQISDLAPDILIIDSIQIIFSPSLSSAPGSVAQVRETTAELMHI
AKQKQITTFIIGHVTKSGEIAGPRILEHLVDTVLYFEGNAHTNYRMIRSVKNRFGPTNELLILSMQTDGLHEVENPSGFF
LQEKVVETTGSTIIPIVEGSETLLVEVQALVSSSPFSNPVRKTSGFDPNRFSLLLAVLEKRANVKLYTSDVFLSIAGGLK
ITQPSADLGAVLSVVSSLYNRYLPKNYTYTGEIGLGGEIRHVTHIEHRIKESIIMGFKGIVMPSGQIKGLPKEYLDQIDI
IGVKTIKDAVRLLQ
>Mature_493_residues
ALLDTMYKSSLMKNFGERALLDQKRKQKNLQLNRRYQHMTTTKIKTQWACSECGSYSPKWLGQCPGCFQWNTLVEEIHSS
KLKTSSYPLSSTTPVPLNTVKFQEEIRISTRSKGWNRLLGGGTVCGSLTLLGGEPGIGKSTLLLQISSQFAEQGYKVLYV
CGEESVSQTSLRAQRLQISSSNIFLFPETNLEDIKQQISDLAPDILIIDSIQIIFSPSLSSAPGSVAQVRETTAELMHIA
KQKQITTFIIGHVTKSGEIAGPRILEHLVDTVLYFEGNAHTNYRMIRSVKNRFGPTNELLILSMQTDGLHEVENPSGFFL
QEKVVETTGSTIIPIVEGSETLLVEVQALVSSSPFSNPVRKTSGFDPNRFSLLLAVLEKRANVKLYTSDVFLSIAGGLKI
TQPSADLGAVLSVVSSLYNRYLPKNYTYTGEIGLGGEIRHVTHIEHRIKESIIMGFKGIVMPSGQIKGLPKEYLDQIDII
GVKTIKDAVRLLQ

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=453, Percent_Identity=41.9426048565121, Blast_Score=370, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 54703; Mature: 54572

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLDTMYKSSLMKNFGERALLDQKRKQKNLQLNRRYQHMTTTKIKTQWACSECGSYSPK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCH
WLGQCPGCFQWNTLVEEIHSSKLKTSSYPLSSTTPVPLNTVKFQEEIRISTRSKGWNRLL
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHEEECCCCCHHHHC
GGGTVCGSLTLLGGEPGIGKSTLLLQISSQFAEQGYKVLYVCGEESVSQTSLRAQRLQIS
CCCEEEEEEEEECCCCCCCCCEEEEEEHHHHHHCCCEEEEEECCCCHHHHHHHHHHEEEC
SSNIFLFPETNLEDIKQQISDLAPDILIIDSIQIIFSPSLSSAPGSVAQVRETTAELMHI
CCCEEEEECCCHHHHHHHHHHHCCCEEEEECEEEEECCCCCCCCCHHHHHHHHHHHHHHH
AKQKQITTFIIGHVTKSGEIAGPRILEHLVDTVLYFEGNAHTNYRMIRSVKNRFGPTNEL
HHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCE
LILSMQTDGLHEVENPSGFFLQEKVVETTGSTIIPIVEGSETLLVEVQALVSSSPFSNPV
EEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCEEEEEEHHHHCCCCCCCCH
RKTSGFDPNRFSLLLAVLEKRANVKLYTSDVFLSIAGGLKITQPSADLGAVLSVVSSLYN
HHCCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEEECCEEEECCCHHHHHHHHHHHHHHH
RYLPKNYTYTGEIGLGGEIRHVTHIEHRIKESIIMGFKGIVMPSGQIKGLPKEYLDQIDI
HHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCCCCE
IGVKTIKDAVRLLQ
EEHHHHHHHHHHCC
>Mature Secondary Structure 
ALLDTMYKSSLMKNFGERALLDQKRKQKNLQLNRRYQHMTTTKIKTQWACSECGSYSPK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCH
WLGQCPGCFQWNTLVEEIHSSKLKTSSYPLSSTTPVPLNTVKFQEEIRISTRSKGWNRLL
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHEEECCCCCHHHHC
GGGTVCGSLTLLGGEPGIGKSTLLLQISSQFAEQGYKVLYVCGEESVSQTSLRAQRLQIS
CCCEEEEEEEEECCCCCCCCCEEEEEEHHHHHHCCCEEEEEECCCCHHHHHHHHHHEEEC
SSNIFLFPETNLEDIKQQISDLAPDILIIDSIQIIFSPSLSSAPGSVAQVRETTAELMHI
CCCEEEEECCCHHHHHHHHHHHCCCEEEEECEEEEECCCCCCCCCHHHHHHHHHHHHHHH
AKQKQITTFIIGHVTKSGEIAGPRILEHLVDTVLYFEGNAHTNYRMIRSVKNRFGPTNEL
HHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCE
LILSMQTDGLHEVENPSGFFLQEKVVETTGSTIIPIVEGSETLLVEVQALVSSSPFSNPV
EEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCEEEEEEHHHHCCCCCCCCH
RKTSGFDPNRFSLLLAVLEKRANVKLYTSDVFLSIAGGLKITQPSADLGAVLSVVSSLYN
HHCCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEEECCEEEECCCHHHHHHHHHHHHHHH
RYLPKNYTYTGEIGLGGEIRHVTHIEHRIKESIIMGFKGIVMPSGQIKGLPKEYLDQIDI
HHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCCCCE
IGVKTIKDAVRLLQ
EEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]