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Identifier: 15835147

GI number: 15835147

Start: 639872

End: 640996

Strand: Reverse

Name: Not Available

Synonym: TC0529

Alternate gene names: 15835147

Gene position: 640996-639872 (Counterclockwise)

Preceding gene: 15835148

Following gene: 15835144

Centisome position: 59.74

GC content: 41.24

Gene sequence:

>1125_bases
ATGACGATATACTTAGATACTAATGCTTCGGCTTTTTTAGATCCGGGCATCTTAATGTATTTACATTCTCTATTTATAGA
AGAAGGAGGGTTTGGGAATCCTTCTAGTGTTCATAGCTTTGGGAAAAAAACAAAACAGCTAATCAAAGAAACTTCCTCTC
TCATAGAAAAGGCTTTAGGGTTTGCTCGGTGTCGCGTGATTTACACTGCTGGAGCAACAGAAAGTCTTAATTTAGCGATT
CAAAATATTCCTCCGGGTAGCCATGTAATCACTTCTAGCATGGAACATCCTGCGGTTATTGAGCCTTTGAAAAAGGCGCA
GCTTTCTGTTACTTATTTAGACCCCATCCCAGGGAAATGTGTCGTTTCTCTAGAACAAATTAAGGACGCTGTCCAGTCGG
ATACTTCAGCTATTGTTTTAGGATGGGTAAATAGCGAGGTTGGGGTAAGGATTAACCTTGAGTCTATAGCTGCATTTGCT
AAAGAACGAAACCTTTTACTTATAGTTGATGCTACGGCGATTGTGGGGAAAGAGGTCATCCGTGTTCCAGAGGGAGTTTC
AATGCTGGCATTTTCTGGACATAAATTTCATGCTTTGTCTGGCATAGGGGTGCTTCTTACTGCCCCAAAAATTAAGCTAT
CTCCAATTATCTTGGGAGGAGGACAGCAGGGGGGGAGCCGTTCAGGGACAGAACATATTCATGGGATAGCTTCCTTACAT
TATATTTTAAAAAAAATATTGGCTGAGCAATCTATTATTTCTCAGACTATGTGCTCCTATCGAGATCTATTTGAATCACA
TTTGCAAGAAGCTTTTCCTGAGTGTGTTGTGCATTGCCAAAAAGAACCTCGAGTTAGCAATCTCTCTGCGATAGCTTTCC
CTGGATTAGAAGGGGAGGTTATGCAGATAGCTTTAGATCTTGAAGGTGTTGCTTGTGGTTATGGTTCCGCATGCTCTTCA
GGAGCAACTACGGTTTTTAAATCATTGACGGCTATGAAAGTGCCTCAGGAGCTTGCTATGGCGACTCTAAGATTTTCCTT
TAGTTATTTGCTTTCAGAACAGGAAGTTCTTACTGCTGTGCAGAAAGTGATTCATGTAGTGCGGCATTTGCAACAATATG
CTTAA

Upstream 100 bases:

>100_bases
CTACCTTAGAAGAAGGCGGGAATATCCTGATTTCCCTAGCAAATAGTCGGGGCGGTAGAGATAATGCTACTGTTGTACTT
GTTCGAATGCGTTAATTTTT

Downstream 100 bases:

>100_bases
CCCATTACAAGGTGTCTTTAATTTCAATGGTCTTGATGCCAGATAGAGAAATTTCTTTTACTTCCAATAGCAAGCCATTA
ATGATGATGGAGGCTCCGAC

Product: nifS protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTIYLDTNASAFLDPGILMYLHSLFIEEGGFGNPSSVHSFGKKTKQLIKETSSLIEKALGFARCRVIYTAGATESLNLAI
QNIPPGSHVITSSMEHPAVIEPLKKAQLSVTYLDPIPGKCVVSLEQIKDAVQSDTSAIVLGWVNSEVGVRINLESIAAFA
KERNLLLIVDATAIVGKEVIRVPEGVSMLAFSGHKFHALSGIGVLLTAPKIKLSPIILGGGQQGGSRSGTEHIHGIASLH
YILKKILAEQSIISQTMCSYRDLFESHLQEAFPECVVHCQKEPRVSNLSAIAFPGLEGEVMQIALDLEGVACGYGSACSS
GATTVFKSLTAMKVPQELAMATLRFSFSYLLSEQEVLTAVQKVIHVVRHLQQYA

Sequences:

>Translated_374_residues
MTIYLDTNASAFLDPGILMYLHSLFIEEGGFGNPSSVHSFGKKTKQLIKETSSLIEKALGFARCRVIYTAGATESLNLAI
QNIPPGSHVITSSMEHPAVIEPLKKAQLSVTYLDPIPGKCVVSLEQIKDAVQSDTSAIVLGWVNSEVGVRINLESIAAFA
KERNLLLIVDATAIVGKEVIRVPEGVSMLAFSGHKFHALSGIGVLLTAPKIKLSPIILGGGQQGGSRSGTEHIHGIASLH
YILKKILAEQSIISQTMCSYRDLFESHLQEAFPECVVHCQKEPRVSNLSAIAFPGLEGEVMQIALDLEGVACGYGSACSS
GATTVFKSLTAMKVPQELAMATLRFSFSYLLSEQEVLTAVQKVIHVVRHLQQYA
>Mature_373_residues
TIYLDTNASAFLDPGILMYLHSLFIEEGGFGNPSSVHSFGKKTKQLIKETSSLIEKALGFARCRVIYTAGATESLNLAIQ
NIPPGSHVITSSMEHPAVIEPLKKAQLSVTYLDPIPGKCVVSLEQIKDAVQSDTSAIVLGWVNSEVGVRINLESIAAFAK
ERNLLLIVDATAIVGKEVIRVPEGVSMLAFSGHKFHALSGIGVLLTAPKIKLSPIILGGGQQGGSRSGTEHIHGIASLHY
ILKKILAEQSIISQTMCSYRDLFESHLQEAFPECVVHCQKEPRVSNLSAIAFPGLEGEVMQIALDLEGVACGYGSACSSG
ATTVFKSLTAMKVPQELAMATLRFSFSYLLSEQEVLTAVQKVIHVVRHLQQYA

Specific function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine [H]

COG id: COG1104

COG function: function code E; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=382, Percent_Identity=26.7015706806283, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI156713448, Length=424, Percent_Identity=26.6509433962264, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI48994898, Length=385, Percent_Identity=29.8701298701299, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25143064, Length=398, Percent_Identity=27.6381909547739, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17533177, Length=323, Percent_Identity=28.1733746130031, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319831, Length=394, Percent_Identity=27.1573604060914, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI20129463, Length=386, Percent_Identity=27.979274611399, Blast_Score=149, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR016454
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 40273; Mature: 40142

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYLDTNASAFLDPGILMYLHSLFIEEGGFGNPSSVHSFGKKTKQLIKETSSLIEKALG
CEEEEECCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FARCRVIYTAGATESLNLAIQNIPPGSHVITSSMEHPAVIEPLKKAQLSVTYLDPIPGKC
HHHEEEEEECCCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHEEEEEEECCCCCHH
VVSLEQIKDAVQSDTSAIVLGWVNSEVGVRINLESIAAFAKERNLLLIVDATAIVGKEVI
EEEHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHCCCEEEEEECHHHHHHHHH
RVPEGVSMLAFSGHKFHALSGIGVLLTAPKIKLSPIILGGGQQGGSRSGTEHIHGIASLH
HCCCCCEEEEECCCCEEEECCCEEEEECCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
YILKKILAEQSIISQTMCSYRDLFESHLQEAFPECVVHCQKEPRVSNLSAIAFPGLEGEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCE
MQIALDLEGVACGYGSACSSGATTVFKSLTAMKVPQELAMATLRFSFSYLLSEQEVLTAV
EEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
QKVIHVVRHLQQYA
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TIYLDTNASAFLDPGILMYLHSLFIEEGGFGNPSSVHSFGKKTKQLIKETSSLIEKALG
EEEEECCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FARCRVIYTAGATESLNLAIQNIPPGSHVITSSMEHPAVIEPLKKAQLSVTYLDPIPGKC
HHHEEEEEECCCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHEEEEEEECCCCCHH
VVSLEQIKDAVQSDTSAIVLGWVNSEVGVRINLESIAAFAKERNLLLIVDATAIVGKEVI
EEEHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHCCCEEEEEECHHHHHHHHH
RVPEGVSMLAFSGHKFHALSGIGVLLTAPKIKLSPIILGGGQQGGSRSGTEHIHGIASLH
HCCCCCEEEEECCCCEEEECCCEEEEECCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
YILKKILAEQSIISQTMCSYRDLFESHLQEAFPECVVHCQKEPRVSNLSAIAFPGLEGEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCE
MQIALDLEGVACGYGSACSSGATTVFKSLTAMKVPQELAMATLRFSFSYLLSEQEVLTAV
EEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
QKVIHVVRHLQQYA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]