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Identifier: 15835107

GI number: 15835107

Start: 594550

End: 595329

Strand: Direct

Name: Not Available

Synonym: TC0489

Alternate gene names: 15835107

Gene position: 594550-595329 (Clockwise)

Preceding gene: 15835106

Following gene: 15835109

Centisome position: 55.41

GC content: 42.05

Gene sequence:

>780_bases
ATGTTTACACTACGAAGCACCCCTCCATGGACAAAATCTGGGAAACGTGTTGAAAGCCTCATTCGTAAGGCATTGTACAC
TTATGCCATGTTAGAGAAGCATACGCATATCGCGGTTGCTCTAAGTGGAGGTAAAGACAGCCTATCTCTTCTGCTTATGC
TGAAAGCTATTTCTGGTAGAGGATTCCCAGAACTAACTATTCATGCGATCCATATTGGAGGCAAATATTCTTGCGGTGCA
GCAGTTAGCGGAAACTATCTTTCTTCTATTTGTGACAAGATTCAAGTCCCACTTATTTCTATTCCTTCCCCTTATGAGAC
AGAGAATCCTGAATGCTACACTTGCTCTCGAATCAGACGACGCCTTCTTTTTGATGCGGCTAAAAGCGTTGGAGCAACAG
CTGTTGCGTTTGGACATCATAGAGATGATGTTATTCAGACAGCACTAATGAATCTTCTTCACAAAGCAGAGTTTGCAGGC
ATGCTTCCTGTCGTAGATATGGTGAATTTTGGAATTACAATCCTGCGTCCCCTTATCTTCATCCCTGAAGAATTAATCCG
TAAATTTGCTAAGGAAAGTGGTTTTGCTCGAATCACCTGCCGTTGCCCAGTCATTTCTCTGCGAACCAAAACCGAAGAAG
CTCTAAAAACCTTAGAAACGATATTTCCTCAAGCAAGGCATAACATTGCTTTAGCTGTTAGAGAATCGGGGCTTATTAAA
GCTAATAACGTCGAGAAGACTGTTTCCATTCAGGACGACAAAAACGCTTTTTCCTTATAA

Upstream 100 bases:

>100_bases
TTAATTAAATAATTTATTCTTTAGTGACGGCCTTCATAAAAGGAAGGCCGTTCCTTCCTTGTTCCTGGATTTCTAATCCG
CAAATCTTTAAAATTCTTCC

Downstream 100 bases:

>100_bases
AGGAATTATGTGATTTGACGAATTGTGGTCGTTTCGACAATCCTACTTTTTGCAGCTTGCGTAATCTTGCTGTTATAGCA
GTTGGGCTACGTCCCGTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MFTLRSTPPWTKSGKRVESLIRKALYTYAMLEKHTHIAVALSGGKDSLSLLLMLKAISGRGFPELTIHAIHIGGKYSCGA
AVSGNYLSSICDKIQVPLISIPSPYETENPECYTCSRIRRRLLFDAAKSVGATAVAFGHHRDDVIQTALMNLLHKAEFAG
MLPVVDMVNFGITILRPLIFIPEELIRKFAKESGFARITCRCPVISLRTKTEEALKTLETIFPQARHNIALAVRESGLIK
ANNVEKTVSIQDDKNAFSL

Sequences:

>Translated_259_residues
MFTLRSTPPWTKSGKRVESLIRKALYTYAMLEKHTHIAVALSGGKDSLSLLLMLKAISGRGFPELTIHAIHIGGKYSCGA
AVSGNYLSSICDKIQVPLISIPSPYETENPECYTCSRIRRRLLFDAAKSVGATAVAFGHHRDDVIQTALMNLLHKAEFAG
MLPVVDMVNFGITILRPLIFIPEELIRKFAKESGFARITCRCPVISLRTKTEEALKTLETIFPQARHNIALAVRESGLIK
ANNVEKTVSIQDDKNAFSL
>Mature_259_residues
MFTLRSTPPWTKSGKRVESLIRKALYTYAMLEKHTHIAVALSGGKDSLSLLLMLKAISGRGFPELTIHAIHIGGKYSCGA
AVSGNYLSSICDKIQVPLISIPSPYETENPECYTCSRIRRRLLFDAAKSVGATAVAFGHHRDDVIQTALMNLLHKAEFAG
MLPVVDMVNFGITILRPLIFIPEELIRKFAKESGFARITCRCPVISLRTKTEEALKTLETIFPQARHNIALAVRESGLIK
ANNVEKTVSIQDDKNAFSL

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=195, Percent_Identity=29.7435897435897, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 28613; Mature: 28613

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLRSTPPWTKSGKRVESLIRKALYTYAMLEKHTHIAVALSGGKDSLSLLLMLKAISGR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCC
GFPELTIHAIHIGGKYSCGAAVSGNYLSSICDKIQVPLISIPSPYETENPECYTCSRIRR
CCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCEEEHHHHHH
RLLFDAAKSVGATAVAFGHHRDDVIQTALMNLLHKAEFAGMLPVVDMVNFGITILRPLIF
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IPEELIRKFAKESGFARITCRCPVISLRTKTEEALKTLETIFPQARHNIALAVRESGLIK
CCHHHHHHHHHHCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCEE
ANNVEKTVSIQDDKNAFSL
ECCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MFTLRSTPPWTKSGKRVESLIRKALYTYAMLEKHTHIAVALSGGKDSLSLLLMLKAISGR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCC
GFPELTIHAIHIGGKYSCGAAVSGNYLSSICDKIQVPLISIPSPYETENPECYTCSRIRR
CCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCEEEHHHHHH
RLLFDAAKSVGATAVAFGHHRDDVIQTALMNLLHKAEFAGMLPVVDMVNFGITILRPLIF
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IPEELIRKFAKESGFARITCRCPVISLRTKTEEALKTLETIFPQARHNIALAVRESGLIK
CCHHHHHHHHHHCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCEE
ANNVEKTVSIQDDKNAFSL
ECCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA