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Identifier: 15835077

GI number: 15835077

Start: 557233

End: 558105

Strand: Reverse

Name: Not Available

Synonym: TC0459

Alternate gene names: 15835077

Gene position: 558105-557233 (Counterclockwise)

Preceding gene: 15835078

Following gene: 15835071

Centisome position: 52.02

GC content: 39.52

Gene sequence:

>873_bases
ATGGAAAGCTCTGCTTGGGACGCTCTTATACAAAGAGTGCGCGATCAGAAGGTTCCTTCTGCTATTATTTTGCATGGGCA
AGATTTGTCGACTTTGTCAACTTGCGCATATGAGTATGCTTCTTTAATTCTTAAAGAAGGCTCCCCGCATGCCTCTTATA
AAATAGCAAATAGATTGCACCCGGATATTTACGAGTATTCCCCTCAAGGGAAGGGACGTCTTCACACGATTGAGACTCCT
CGAGCTATTAGAAAAAATATCTGGATACATCCTTATGAAAGCTCTTATAAAATTTATATTATTTATGAAGCTGACAGGAT
ATCATTAGACGCTATATCAGCTTTTTTAAAACTTTTAGAAGATCCTCCGTATTACAGTATATTTATACTCGTTTCAGCAC
TTCCACAGAGGTTGCCGCCCACCATTCGATCTAGATGCGTGTCATTCCATATTCCTTTAGAAAAAAGGGATTTAATTGAT
AAGAAAGACATCTCATTTTTAATCAGCTTAGCAAAAGGTAAAGAATCTGTGATGCGAGTGGGATCTAGGGTAAAAGGAGC
ACCTGATGACGATAAGCAAGTGCTTCGAGATAAAACAAAAGCCATGTTAACCGTTCTTTTGCAGTTATTCAGGGATCGGT
TTTTCTTGGCCAAGAAGATGCCAGAGTCTCTACTTACCTATCCGGATTTTTTAGATGAGATAAAAACTATGCCGGTATAT
CCCCTGGAAGAGGTTCTTTCAATTATTACTCGGGCTGTGCAAGCTCTTGATACATACTCTTCCGCGTCAAGCTGTCTAGA
ATGGATGTCTTTGCAGTTATGGTCTTTTAGAAATCGTCAAAGGACAGCTATCCGCAATCGAAAAGGATGTTAA

Upstream 100 bases:

>100_bases
AGACAGGTATAAAATTTTAGATGCATTATTACCAACAGAGGTATCTGTCGATCAAGCTCTTTTACAGATTCGAGCATTGA
TATAGAAAGGGGGGGGAGAG

Downstream 100 bases:

>100_bases
AACATTTCTAATTTACATTCTGCAGGAATATCTGCAAGATCCGCCGCTCTACAACAATCAGATGACAATACCCATTGCAG
AGGATTTAGAGGAGTCCCTA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MESSAWDALIQRVRDQKVPSAIILHGQDLSTLSTCAYEYASLILKEGSPHASYKIANRLHPDIYEYSPQGKGRLHTIETP
RAIRKNIWIHPYESSYKIYIIYEADRISLDAISAFLKLLEDPPYYSIFILVSALPQRLPPTIRSRCVSFHIPLEKRDLID
KKDISFLISLAKGKESVMRVGSRVKGAPDDDKQVLRDKTKAMLTVLLQLFRDRFFLAKKMPESLLTYPDFLDEIKTMPVY
PLEEVLSIITRAVQALDTYSSASSCLEWMSLQLWSFRNRQRTAIRNRKGC

Sequences:

>Translated_290_residues
MESSAWDALIQRVRDQKVPSAIILHGQDLSTLSTCAYEYASLILKEGSPHASYKIANRLHPDIYEYSPQGKGRLHTIETP
RAIRKNIWIHPYESSYKIYIIYEADRISLDAISAFLKLLEDPPYYSIFILVSALPQRLPPTIRSRCVSFHIPLEKRDLID
KKDISFLISLAKGKESVMRVGSRVKGAPDDDKQVLRDKTKAMLTVLLQLFRDRFFLAKKMPESLLTYPDFLDEIKTMPVY
PLEEVLSIITRAVQALDTYSSASSCLEWMSLQLWSFRNRQRTAIRNRKGC
>Mature_290_residues
MESSAWDALIQRVRDQKVPSAIILHGQDLSTLSTCAYEYASLILKEGSPHASYKIANRLHPDIYEYSPQGKGRLHTIETP
RAIRKNIWIHPYESSYKIYIIYEADRISLDAISAFLKLLEDPPYYSIFILVSALPQRLPPTIRSRCVSFHIPLEKRDLID
KKDISFLISLAKGKESVMRVGSRVKGAPDDDKQVLRDKTKAMLTVLLQLFRDRFFLAKKMPESLLTYPDFLDEIKTMPVY
PLEEVLSIITRAVQALDTYSSASSCLEWMSLQLWSFRNRQRTAIRNRKGC

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=75, Percent_Identity=38.6666666666667, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 33387; Mature: 33387

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSAWDALIQRVRDQKVPSAIILHGQDLSTLSTCAYEYASLILKEGSPHASYKIANRLH
CCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
PDIYEYSPQGKGRLHTIETPRAIRKNIWIHPYESSYKIYIIYEADRISLDAISAFLKLLE
CHHHHCCCCCCCCEEEECCCHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHC
DPPYYSIFILVSALPQRLPPTIRSRCVSFHIPLEKRDLIDKKDISFLISLAKGKESVMRV
CCCCHHHHHHHHHHHHHCCHHHHHHHHEEECCCHHHHCCCHHHHHHHHHHHHCHHHHHHH
GSRVKGAPDDDKQVLRDKTKAMLTVLLQLFRDRFFLAKKMPESLLTYPDFLDEIKTMPVY
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCC
PLEEVLSIITRAVQALDTYSSASSCLEWMSLQLWSFRNRQRTAIRNRKGC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure
MESSAWDALIQRVRDQKVPSAIILHGQDLSTLSTCAYEYASLILKEGSPHASYKIANRLH
CCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
PDIYEYSPQGKGRLHTIETPRAIRKNIWIHPYESSYKIYIIYEADRISLDAISAFLKLLE
CHHHHCCCCCCCCEEEECCCHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHC
DPPYYSIFILVSALPQRLPPTIRSRCVSFHIPLEKRDLIDKKDISFLISLAKGKESVMRV
CCCCHHHHHHHHHHHHHCCHHHHHHHHEEECCCHHHHCCCHHHHHHHHHHHHCHHHHHHH
GSRVKGAPDDDKQVLRDKTKAMLTVLLQLFRDRFFLAKKMPESLLTYPDFLDEIKTMPVY
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCC
PLEEVLSIITRAVQALDTYSSASSCLEWMSLQLWSFRNRQRTAIRNRKGC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]