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The map label for this gene is rpe

Identifier: 15835016

GI number: 15835016

Start: 458899

End: 459585

Strand: Direct

Name: rpe

Synonym: TC0397

Alternate gene names: 15835016

Gene position: 458899-459585 (Clockwise)

Preceding gene: 15835014

Following gene: 15835017

Centisome position: 42.77

GC content: 39.88

Gene sequence:

>687_bases
ATGAAAAAACAAGGGGTGTTAATTGCTCCATCTATTATGGGGGCCGACTTGGCTTGCCTAGGGGATGCAGCACGAAATAT
AGAAGAGTCTGGGGCAAATCTTATTCATATAGATGTCATGGATGGGCATTTTGTTCCGAATATTACCTTTGGTCCCGGTA
TTATTGCCGCAATCAATCGGTCAACAGATCTATTCCTTGAAGTTCATGCTATGATTTATACGCCGTTTGAATTTGTAGAG
GCTTTTGTTAAAGCTGGAGCAGATCGTATTATTGTGCACTTTGAGGCAGCAGAAAACCTTAAAGAAATTCTTGATTATAT
TCGAAAATGTGGAGTGCAGGCAGGGATCGCTTTTTCTCCAGAGACTTCTATTGAGTTCATCTCGGCTTTTATACCTTTGT
GTGATGTCATTCTACTTATGTCTGTACAACCGGGATTTTGTGGTCAAAAATTTATTCCTGATACGATAGAAAAGATTCGA
TTTGTTAGACAGGCAATACAAACTCTTGGGAAAGAGGGAAGTTGCTTGATCGAAGTTGACGGTGGTATTGATGAGGAGTC
TGCCCGAGCATGTAGAGAAGCCGGTGCCGATATTTTGGTTGCCGCTTCTTATTTTTTTAAAAAAGACTCTATAAATATGA
AAGAAAAAGTTTTGTTACTTCAAGGGGAAGAACATGGTGCTAAGTAG

Upstream 100 bases:

>100_bases
ACCATTGTACACTTTCCTCTTGTCATGAAGAGTGAAAAATTTTGATTACAGGGGTGATACCTGTATCAGCGTCTCTAGAG
AAGAAAGAGAGAGAAAGATC

Downstream 100 bases:

>100_bases
CCAACTCTCAGTAGGGATGTTTATCTCTACAAAAGATGGCCTGTATAAAGTGGTTTCTGTTTCAAAAGTTTCAGGAAGCA
AGGGAGATACCTTTATTAAG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKKQGVLIAPSIMGADLACLGDAARNIEESGANLIHIDVMDGHFVPNITFGPGIIAAINRSTDLFLEVHAMIYTPFEFVE
AFVKAGADRIIVHFEAAENLKEILDYIRKCGVQAGIAFSPETSIEFISAFIPLCDVILLMSVQPGFCGQKFIPDTIEKIR
FVRQAIQTLGKEGSCLIEVDGGIDEESARACREAGADILVAASYFFKKDSINMKEKVLLLQGEEHGAK

Sequences:

>Translated_228_residues
MKKQGVLIAPSIMGADLACLGDAARNIEESGANLIHIDVMDGHFVPNITFGPGIIAAINRSTDLFLEVHAMIYTPFEFVE
AFVKAGADRIIVHFEAAENLKEILDYIRKCGVQAGIAFSPETSIEFISAFIPLCDVILLMSVQPGFCGQKFIPDTIEKIR
FVRQAIQTLGKEGSCLIEVDGGIDEESARACREAGADILVAASYFFKKDSINMKEKVLLLQGEEHGAK
>Mature_228_residues
MKKQGVLIAPSIMGADLACLGDAARNIEESGANLIHIDVMDGHFVPNITFGPGIIAAINRSTDLFLEVHAMIYTPFEFVE
AFVKAGADRIIVHFEAAENLKEILDYIRKCGVQAGIAFSPETSIEFISAFIPLCDVILLMSVQPGFCGQKFIPDTIEKIR
FVRQAIQTLGKEGSCLIEVDGGIDEESARACREAGADILVAASYFFKKDSINMKEKVLLLQGEEHGAK

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family

Homologues:

Organism=Homo sapiens, GI40385883, Length=207, Percent_Identity=38.1642512077295, Blast_Score=164, Evalue=5e-41,
Organism=Homo sapiens, GI219879828, Length=207, Percent_Identity=36.7149758454106, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI24307923, Length=160, Percent_Identity=31.25, Blast_Score=98, Evalue=7e-21,
Organism=Escherichia coli, GI1789788, Length=203, Percent_Identity=40.8866995073892, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790523, Length=222, Percent_Identity=31.5315315315315, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1790754, Length=178, Percent_Identity=30.8988764044944, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=206, Percent_Identity=37.378640776699, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=36.2445414847162, Blast_Score=149, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24586301, Length=197, Percent_Identity=33.502538071066, Blast_Score=147, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPE_CHLMU (Q9PKR7)

Other databases:

- EMBL:   AE002160
- PIR:   A81708
- RefSeq:   NP_296775.1
- ProteinModelPortal:   Q9PKR7
- SMR:   Q9PKR7
- GeneID:   1245749
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0397
- TIGR:   TC_0397
- HOGENOM:   HBG571751
- OMA:   QSFINPM
- ProtClustDB:   PRK05581
- BioCyc:   CMUR243161:TC_0397-MONOMER
- BRENDA:   5.1.3.1
- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR11749
- PIRSF:   PIRSF001461
- TIGRFAMs:   TIGR01163

Pfam domain/function: PF00834 Ribul_P_3_epim; SSF51366 RibP_bind_barrel

EC number: =5.1.3.1

Molecular weight: Translated: 24823; Mature: 24823

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQGVLIAPSIMGADLACLGDAARNIEESGANLIHIDVMDGHFVPNITFGPGIIAAINR
CCCCCEEEECHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEECCCEEEEECC
STDLFLEVHAMIYTPFEFVEAFVKAGADRIIVHFEAAENLKEILDYIRKCGVQAGIAFSP
CCHHHEEHHHHHHCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEECC
ETSIEFISAFIPLCDVILLMSVQPGFCGQKFIPDTIEKIRFVRQAIQTLGKEGSCLIEVD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GGIDEESARACREAGADILVAASYFFKKDSINMKEKVLLLQGEEHGAK
CCCCHHHHHHHHHCCCCEEEEHHHHHCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKKQGVLIAPSIMGADLACLGDAARNIEESGANLIHIDVMDGHFVPNITFGPGIIAAINR
CCCCCEEEECHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEECCCEEEEECC
STDLFLEVHAMIYTPFEFVEAFVKAGADRIIVHFEAAENLKEILDYIRKCGVQAGIAFSP
CCHHHEEHHHHHHCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEECC
ETSIEFISAFIPLCDVILLMSVQPGFCGQKFIPDTIEKIRFVRQAIQTLGKEGSCLIEVD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GGIDEESARACREAGADILVAASYFFKKDSINMKEKVLLLQGEEHGAK
CCCCHHHHHHHHHCCCCEEEEHHHHHCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935