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Identifier: 15834761

GI number: 15834761

Start: 172318

End: 173541

Strand: Direct

Name: Not Available

Synonym: TC0141

Alternate gene names: 15834761

Gene position: 172318-173541 (Clockwise)

Preceding gene: 15834760

Following gene: 15834762

Centisome position: 16.06

GC content: 40.85

Gene sequence:

>1224_bases
ATGAGCAGAAAGCTCGTAAGTTGCGTCCTGGAGATAGATTACGAATTCGATAGATCTCAGGCAATTGTTATGAAATGGTT
CCTGATTTCCTGTTTATTAGGAATTTTTTCTCTTGGGCTGATCATGGTATTCGATACCTCGTCGGCAGAAGTGTTGGATC
GGGCTTTGTCGTGTAGCACGCATAAAGCTTTGATCCGGCAGATAACCTATCTGGTGCTAGGGCTCTCTGTTGCGTCGTTC
ATTTATATTTTAGGATGGAAAGATTTTCTTAAGATGAGCCCTGTACTCCTCATCATGGTGGGGATGGCTTTGATTTTAGT
GCTTATTCCAGGTGTCGGTGTTTGTAGAAATGGAGCTAGACGTTGGTTAGGAGTAGGACAGCTAACATTGCAACCGTCCG
AGTTTGTTAAATATTTAATTCCTTGTGTTGCTATCGAATGTTTGACCACAAGAGTCGCTATTCGTAGTAGTTTTAAGCGA
TTCGTTGCTTTTGTTTCCTTGCTATTTATTCCTATTTTTTTGATTGCGATTGAGCCGGATAATGGATCTGCAGCGGTAAT
TGCTTTTTCTTTAATTCCTGTGTTTATTGTTACAGCGGTACGATTGCGTTATTGGCTCGTTCCTTTGCTCTGTATCCTTT
GTATCGGAGGCATTTTTGCTTATCGGCTTCCTTATGTTCGAAATCGTTTACAGGTTTATTTGCATCCAGAATTAGATATT
AAAGGGAGAGGGCATCAACCATATCAAGCAAAGATCGCAGCAGGATCTGGGAAGTTATTCGGTAAAGGTCCCGGAAAGGG
ATTGCAGAAATTAACCTATCTTCCAGAAGCTCAGAATGATTATATTGCAGCTATCTATGCGGAAGAGTTTGGTTTTGTTG
GGATGCTCCTATTGATTCTTCTCTATATGGGATTTATTTATAGTGGATATGTCATTGCTATGAGGGCTTCCCTTTTATCT
GGAGCAGCTCTTGCTATTTCAATTACTGTGATTATTGGGATGCAGGCATTTATCAATTTAGGAGTTGTTTCTGGGTTATT
GCCTAGTAAGGGAGTGAATCTTCCTTTTTTTAGTCAGGGAGGATCTTCTCTAATTGCTAATATGTGTGGCATTGGATTGC
TATTAAGGATATGTGATGAAGAAGATCAGCAAGGTTGTATTGGCAGTAGGGGGAACAGGGGGACACATTATCCCCGCTTT
AGCAGCCAGAGAGACTTTCATTAA

Upstream 100 bases:

>100_bases
CCAGAAGATTATTATGTGATTAAAGAAGGGGATAGTCCTTGGGCTATAGCTTTGAGTAATGGGATTCGATTAGATGAATT
GTTGAAATTGAATGGATTAG

Downstream 100 bases:

>100_bases
GGAGAAAGTAGAAGTTCTACTTTTAGGAAAGGGGTTAACGCGTTTCTTGGAAGGAGAACCAGATGTATTGTACTACGATA
TTCCTTCTGGATCTCCCTTT

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSRKLVSCVLEIDYEFDRSQAIVMKWFLISCLLGIFSLGLIMVFDTSSAEVLDRALSCSTHKALIRQITYLVLGLSVASF
IYILGWKDFLKMSPVLLIMVGMALILVLIPGVGVCRNGARRWLGVGQLTLQPSEFVKYLIPCVAIECLTTRVAIRSSFKR
FVAFVSLLFIPIFLIAIEPDNGSAAVIAFSLIPVFIVTAVRLRYWLVPLLCILCIGGIFAYRLPYVRNRLQVYLHPELDI
KGRGHQPYQAKIAAGSGKLFGKGPGKGLQKLTYLPEAQNDYIAAIYAEEFGFVGMLLLILLYMGFIYSGYVIAMRASLLS
GAALAISITVIIGMQAFINLGVVSGLLPSKGVNLPFFSQGGSSLIANMCGIGLLLRICDEEDQQGCIGSRGNRGTHYPRF
SSQRDFH

Sequences:

>Translated_407_residues
MSRKLVSCVLEIDYEFDRSQAIVMKWFLISCLLGIFSLGLIMVFDTSSAEVLDRALSCSTHKALIRQITYLVLGLSVASF
IYILGWKDFLKMSPVLLIMVGMALILVLIPGVGVCRNGARRWLGVGQLTLQPSEFVKYLIPCVAIECLTTRVAIRSSFKR
FVAFVSLLFIPIFLIAIEPDNGSAAVIAFSLIPVFIVTAVRLRYWLVPLLCILCIGGIFAYRLPYVRNRLQVYLHPELDI
KGRGHQPYQAKIAAGSGKLFGKGPGKGLQKLTYLPEAQNDYIAAIYAEEFGFVGMLLLILLYMGFIYSGYVIAMRASLLS
GAALAISITVIIGMQAFINLGVVSGLLPSKGVNLPFFSQGGSSLIANMCGIGLLLRICDEEDQQGCIGSRGNRGTHYPRF
SSQRDFH
>Mature_406_residues
SRKLVSCVLEIDYEFDRSQAIVMKWFLISCLLGIFSLGLIMVFDTSSAEVLDRALSCSTHKALIRQITYLVLGLSVASFI
YILGWKDFLKMSPVLLIMVGMALILVLIPGVGVCRNGARRWLGVGQLTLQPSEFVKYLIPCVAIECLTTRVAIRSSFKRF
VAFVSLLFIPIFLIAIEPDNGSAAVIAFSLIPVFIVTAVRLRYWLVPLLCILCIGGIFAYRLPYVRNRLQVYLHPELDIK
GRGHQPYQAKIAAGSGKLFGKGPGKGLQKLTYLPEAQNDYIAAIYAEEFGFVGMLLLILLYMGFIYSGYVIAMRASLLSG
AALAISITVIIGMQAFINLGVVSGLLPSKGVNLPFFSQGGSSLIANMCGIGLLLRICDEEDQQGCIGSRGNRGTHYPRFS
SQRDFH

Specific function: May play an essential role not only during sporulation, but also during vegetative growth [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=388, Percent_Identity=29.8969072164948, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1786853, Length=277, Percent_Identity=37.5451263537906, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- InterPro:   IPR013438 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44763; Mature: 44632

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKLVSCVLEIDYEFDRSQAIVMKWFLISCLLGIFSLGLIMVFDTSSAEVLDRALSCST
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCHH
HKALIRQITYLVLGLSVASFIYILGWKDFLKMSPVLLIMVGMALILVLIPGVGVCRNGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHH
RWLGVGQLTLQPSEFVKYLIPCVAIECLTTRVAIRSSFKRFVAFVSLLFIPIFLIAIEPD
HHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
NGSAAVIAFSLIPVFIVTAVRLRYWLVPLLCILCIGGIFAYRLPYVRNRLQVYLHPELDI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
KGRGHQPYQAKIAAGSGKLFGKGPGKGLQKLTYLPEAQNDYIAAIYAEEFGFVGMLLLIL
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEHHHCCHHHHHHHHH
LYMGFIYSGYVIAMRASLLSGAALAISITVIIGMQAFINLGVVSGLLPSKGVNLPFFSQG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GSSLIANMCGIGLLLRICDEEDQQGCIGSRGNRGTHYPRFSSQRDFH
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRKLVSCVLEIDYEFDRSQAIVMKWFLISCLLGIFSLGLIMVFDTSSAEVLDRALSCST
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCHH
HKALIRQITYLVLGLSVASFIYILGWKDFLKMSPVLLIMVGMALILVLIPGVGVCRNGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHH
RWLGVGQLTLQPSEFVKYLIPCVAIECLTTRVAIRSSFKRFVAFVSLLFIPIFLIAIEPD
HHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
NGSAAVIAFSLIPVFIVTAVRLRYWLVPLLCILCIGGIFAYRLPYVRNRLQVYLHPELDI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
KGRGHQPYQAKIAAGSGKLFGKGPGKGLQKLTYLPEAQNDYIAAIYAEEFGFVGMLLLIL
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEHHHCCHHHHHHHHH
LYMGFIYSGYVIAMRASLLSGAALAISITVIIGMQAFINLGVVSGLLPSKGVNLPFFSQG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GSSLIANMCGIGLLLRICDEEDQQGCIGSRGNRGTHYPRFSSQRDFH
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2115675; 3098901; 9384377; 8436954; 1391053 [H]