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The map label for this gene is mraY

Identifier: 15834758

GI number: 15834758

Start: 169373

End: 170380

Strand: Direct

Name: mraY

Synonym: TC0138

Alternate gene names: 15834758

Gene position: 169373-170380 (Clockwise)

Preceding gene: 15834757

Following gene: 15834759

Centisome position: 15.79

GC content: 40.48

Gene sequence:

>1008_bases
ATGCCCCCCCTATTTTGTGTTTTGAAAGCTTTTTTCATCGGTTTGGTTGTTAGCCTTATACTGGTGAAACCTCTTATTTG
GTTAAAAAAACAAGGCTTGCAAGATCGGATTCACAAAGATCATTGCGAAAAATTGGAAAAGCTACACAAAAACAAAGCAC
ATATCCCCACAGCGGGGGGAATCATTTTTGTTCTTTCTGTCGTTCTCTCAATTCTTTTATTATTGCCTTGCAATCTTTGG
TCGACATGGTTTCTTGTCGGGGCAACGCTGCTGTGGGGGGCTTTGGGATGGCGTGATGATCAGATAAAAAATAAGCGTAA
AGTAGGTCATGGCTTGTCGGCTAAGCGTAAGTTTTTTATCCAAAATTGTTTAGCGATCGGAACCGTTCTTCCTATCATGA
TCGCTTATGGAGAAAGCTTTTTATGTATGCATCTTCCCTTTGTGGGGATAGTATCTTTACCACATTGTTGGTTGGGCTAT
CTGTTTAGTTTTTCTATTGCAGTACTAGCAATTGTTGGAACCAGCAATTCTGTTAACCTGACAGATGGATTAGATGGTCT
TGCTGCAGGATCTATGGTGATAGCTTGTTTGGGCATGCTTATCGTGACTTTTGCTTATGGAGCCCCTTGGGCTTTCATTT
CTGGGGTGCTTTTAGCAACTTTAGCAGGAAGTTGTTTAGGATTTTTATACTATAATAGGTCTCCGGCTCGCATATTTATG
GGGGATACGGGGTCTCTATTTTTAGGTGGGATGCTCGGGATTTGTGCGGTATTATTACGAGCCGAGTTTATGCTCCTCTT
TATGGGAGGGATTTTTGTTCTTGAATCCTTGTCTGTCATTTTGCAGGTGGGGAGTTGTAAATTAAGAAAAAAAAGAGTTT
TTCTTTGCTCTCCTCTACATCACCATTATGAATATAAAGGGTATCCAGAAAAGGTTGTGGTGAGAAATTTTTGGATTATT
GAGTTCCTTTGTGTTGCCATTGGTATTTTCGCTGTATTTTGGGGTTAG

Upstream 100 bases:

>100_bases
TTTCTTTTTAAAATAAGAAAAGAAATAGTTAGTTTTTGATGCTTAAGTTTAAGATAGAGAACTCCTTATAGTCGACACTC
TCATAAACAAGAGAAAACAG

Downstream 100 bases:

>100_bases
AGGATAAGCGAATGGGATTAAAACGTGTTGTAGTTATTGGCTTAGGACTATCTGGTAAGTCTATTGCGCGTTTCTTAGCT
CGAAAAGGCGTGTATGTGTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPPLFCVLKAFFIGLVVSLILVKPLIWLKKQGLQDRIHKDHCEKLEKLHKNKAHIPTAGGIIFVLSVVLSILLLLPCNLW
STWFLVGATLLWGALGWRDDQIKNKRKVGHGLSAKRKFFIQNCLAIGTVLPIMIAYGESFLCMHLPFVGIVSLPHCWLGY
LFSFSIAVLAIVGTSNSVNLTDGLDGLAAGSMVIACLGMLIVTFAYGAPWAFISGVLLATLAGSCLGFLYYNRSPARIFM
GDTGSLFLGGMLGICAVLLRAEFMLLFMGGIFVLESLSVILQVGSCKLRKKRVFLCSPLHHHYEYKGYPEKVVVRNFWII
EFLCVAIGIFAVFWG

Sequences:

>Translated_335_residues
MPPLFCVLKAFFIGLVVSLILVKPLIWLKKQGLQDRIHKDHCEKLEKLHKNKAHIPTAGGIIFVLSVVLSILLLLPCNLW
STWFLVGATLLWGALGWRDDQIKNKRKVGHGLSAKRKFFIQNCLAIGTVLPIMIAYGESFLCMHLPFVGIVSLPHCWLGY
LFSFSIAVLAIVGTSNSVNLTDGLDGLAAGSMVIACLGMLIVTFAYGAPWAFISGVLLATLAGSCLGFLYYNRSPARIFM
GDTGSLFLGGMLGICAVLLRAEFMLLFMGGIFVLESLSVILQVGSCKLRKKRVFLCSPLHHHYEYKGYPEKVVVRNFWII
EFLCVAIGIFAVFWG
>Mature_334_residues
PPLFCVLKAFFIGLVVSLILVKPLIWLKKQGLQDRIHKDHCEKLEKLHKNKAHIPTAGGIIFVLSVVLSILLLLPCNLWS
TWFLVGATLLWGALGWRDDQIKNKRKVGHGLSAKRKFFIQNCLAIGTVLPIMIAYGESFLCMHLPFVGIVSLPHCWLGYL
FSFSIAVLAIVGTSNSVNLTDGLDGLAAGSMVIACLGMLIVTFAYGAPWAFISGVLLATLAGSCLGFLYYNRSPARIFMG
DTGSLFLGGMLGICAVLLRAEFMLLFMGGIFVLESLSVILQVGSCKLRKKRVFLCSPLHHHYEYKGYPEKVVVRNFWIIE
FLCVAIGIFAVFWG

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=317, Percent_Identity=41.9558359621451, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_CHLMU (Q9PLG6)

Other databases:

- EMBL:   AE002160
- PIR:   E81736
- RefSeq:   NP_296517.1
- GeneID:   1245672
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0138
- TIGR:   TC_0138
- HOGENOM:   HBG708263
- OMA:   RSPARIF
- ProtClustDB:   PRK00108
- BioCyc:   CMUR243161:TC_0138-MONOMER
- BRENDA:   2.7.8.13
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 36987; Mature: 36856

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb38da80)-; HASH(0xbdbaab8)-; HASH(0xae20cf0)-; HASH(0xbb98c00)-; HASH(0xae20c6c)-; HASH(0xc0e6f40)-; HASH(0xb2571ec)-; HASH(0xbb92a70)-; HASH(0xc0e6dcc)-;

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
PPLFCVLKAFFIGLVVSLILVKPLIWLKKQGLQDRIHKDHCEKLEKLHKNKAHIPTAGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH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HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10684935